Medicinal value of asiaticoside for Alzheimer's disease as assessed using single-molecule-detection fluorescence correlation spectroscopy, laser-scanning microscopy, transmission electron microscopy, and in silico docking

BMC Complementary and Alternative Medicine

Volumn 15, Issue 1, 2015, Pages

  Hossain, Shahdat ^a,b   Hashimoto, Michio ^a   Katakura, Masanori ^a   Al Mamun, Abdullah ^a   Shido, Osamu ^a  

^a SHIMANE UNIVERSITY FACULTY OF MEDICINE   (Japan)

^b JAHANGIRNAGAR UNIVERSITY   (Bangladesh)

Author keywords

Amyloid fibrillation; Asiaticoside; Fluorescence correlation spectroscopy; Molecular Docking; Neurotoxicity

Indexed keywords

5 CARBOXYTETRAMETHYLRHODAMINE; AMYLOID BETA PROTEIN[1-42]; ASIATICOSIDE; FLUORESCENT DYE; MONOMER; TETRAMETHYLRHODAMINE; THIOFLAVINE; UNCLASSIFIED DRUG; 5-CARBOXYTETRAMETHYLRHODAMINE; AMYLOID; AMYLOID BETA PROTEIN; AMYLOID BETA-PROTEIN (1-42); PEPTIDE FRAGMENT; PLANT EXTRACT; RHODAMINE; TRITERPENE;

ALZHEIMER DISEASE; ARTICLE; BINDING SITE; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; DRUG EFFECT; DRUG PROTEIN BINDING; DRUG STRUCTURE; FLUORESCENCE ANALYSIS; FLUORESCENCE CORRELATION SPECTROSCOPY; FLUOROSPECTROSCOPY; INCUBATION TIME; INHIBITION KINETICS; LASER MICROSCOPY; MOLECULAR DOCKING; MOLECULAR INTERACTION; PROTEIN AGGREGATION; RESIDUE ANALYSIS; SPECTROSCOPY; STEADY STATE; TRANSMISSION ELECTRON MICROSCOPY; CENTELLA; CHEMISTRY; FLUORESCENCE; HUMAN; METABOLISM; MICROSCOPY; PHYTOTHERAPY; PROCEDURES;

ALZHEIMER DISEASE; AMYLOID; AMYLOID BETA-PEPTIDES; CENTELLA; FLUORESCENCE; HUMANS; MICROSCOPY; MOLECULAR DOCKING SIMULATION; PEPTIDE FRAGMENTS; PHYTOTHERAPY; PLANT EXTRACTS; RHODAMINES; SPECTRUM ANALYSIS; TRITERPENES;

EID: 84928818849     PISSN: None     EISSN: 14726882     Source Type: Journal    
DOI: 10.1186/s12906-015-0620-9     Document Type: Article

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