Homeostatic regulation of KCC2 activity by the zinc receptor mZnR/GPR39 during seizures

Neurobiology of Disease

Volumn 81, Issue , 2015, Pages 4-13

  Gilad, David ^a   Shorer, Sharon ^a   Ketzef, Maya ^a   Friedman, Alon ^a   Sekler, Israel ^a   Aizenman, Elias ^a,b   Hershfinkel, Michal ^a  

^a BEN GURION UNIVERSITY OF THE NEGEV   (Israel)

^b UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

Author keywords

Epilepsy; Hippocampus; Kainic acid; KCC2; MZnR GPR39; Seizure; Zinc receptor

Indexed keywords

G PROTEIN COUPLED RECEPTOR; G PROTEIN COUPLED RECEPTOR 39; GUANINE NUCLEOTIDE BINDING PROTEIN; GUANINE NUCLEOTIDE BINDING PROTEIN GQ ALPHA; KAINIC ACID; METABOTROPIC ZINC RECEPTOR; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; PHOSPHOLIPASE C; POTASSIUM CHLORIDE COTRANSPORTER 2; UNCLASSIFIED DRUG; AMINO ACID RECEPTOR STIMULATING AGENT; COTRANSPORTER; EDETIC ACID; FLUORESCEIN DERIVATIVE; GPR37 PROTEIN, MOUSE; POTASSIUM-CHLORIDE SYMPORTERS; ZINC; ZINPYR-1;

ADULT; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CATION TRANSPORT; CONTROLLED STUDY; DISEASE PREDISPOSITION; ENZYME ACTIVITY; ENZYME INHIBITION; ENZYME REGULATION; FEMALE; HIPPOCAMPUS; IN VIVO STUDY; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; SEIZURE; SIGNAL TRANSDUCTION; UPREGULATION; ZINC TRANSPORT; ACTION POTENTIAL; ANIMAL; CHEMICALLY INDUCED; DISEASE MODEL; DRUG EFFECTS; GAMMA RHYTHM; GENE EXPRESSION REGULATION; GENETICS; HOMEOSTASIS; IN VITRO STUDY; METABOLISM; NEWBORN; NONPARAMETRIC TEST; PATHOLOGY; PROTEIN TRANSPORT; TRANSGENIC MOUSE;

ACTION POTENTIALS; ANIMALS; ANIMALS, NEWBORN; DISEASE MODELS, ANIMAL; EDETIC ACID; EXCITATORY AMINO ACID AGONISTS; FLUORESCEINS; GAMMA RHYTHM; GENE EXPRESSION REGULATION; HIPPOCAMPUS; HOMEOSTASIS; IN VITRO TECHNIQUES; KAINIC ACID; MICE; MICE, TRANSGENIC; PROTEIN TRANSPORT; RECEPTORS, G-PROTEIN-COUPLED; SEIZURES; STATISTICS, NONPARAMETRIC; SYMPORTERS; ZINC;

EID: 84928815072     PISSN: 09699961     EISSN: 1095953X     Source Type: Journal    
DOI: 10.1016/j.nbd.2014.12.020     Document Type: Article

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