Astrocytes protect neurons from Aβ1-42 peptide-induced neurotoxicity increasing TFAM and PGC-1 and decreasing PPAR-γ and SIRT-1

International Journal of Medical Sciences

Volumn 12, Issue 1, 2015, Pages 48-56

  Aguirre Rueda, Diana ^a   Guerra Ojeda, Sol ^a   Aldasoro, Martin ^a   Iradi, Antonio ^a   Obrador, Elena ^a   Ortega, Angel ^a   Mauricio, M Dolores ^a   Vila, Jose Mª ^a   Valles, Soraya L ^a  

^a UNIVERSITY OF VALENCIA   (Spain)

Author keywords

Alzheimer s disease; MnSOD; NF B; PGC 1; PPAR ; TFAM

Indexed keywords

AMYLOID BETA PROTEIN[1-42]; CELL PROTEIN; I KAPPA B; MITOCHONDRIAL TRANSCRIPTION FACTOR A; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA COACTIVATOR 1; SIRTUIN 1; TRANSCRIPTION FACTOR RELA; UNCLASSIFIED DRUG; AMYLOID BETA PROTEIN; AMYLOID BETA-PROTEIN (1-42); AMYLOID BETA-PROTEIN (40-1); CASPASE 3; PEPTIDE FRAGMENT; PEROXIDE; PPARGC1A PROTEIN, RAT; RELA PROTEIN, RAT; SIRT1 PROTEIN, RAT; SUPEROXIDE DISMUTASE; TFAM PROTEIN, RAT; TRANSCRIPTION FACTOR;

ALZHEIMER DISEASE; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; APOPTOSIS; ARTICLE; ASTROCYTE; BIOGENESIS; BRAIN MITOCHONDRION; CELL VIABILITY; CONTROLLED STUDY; EPIGENETICS; FETUS; INFLAMMATION; LIPID PEROXIDATION; NERVE CELL NECROSIS; NERVE CELL STIMULATION; NEUROPROTECTION; NEUROTOXICITY; NONHUMAN; OXIDATIVE STRESS; PATHOPHYSIOLOGY; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN LOCALIZATION; PROTEIN PROTEIN INTERACTION; RAT; ANIMAL; CELL CULTURE; CELL DEATH; COCULTURE; CYTOLOGY; DRUG EFFECTS; METABOLISM; MITOCHONDRION; NERVE CELL; PATHOLOGY;

AMYLOID BETA-PEPTIDES; ANIMALS; ASTROCYTES; CASPASE 3; CELL DEATH; CELLS, CULTURED; COCULTURE TECHNIQUES; LIPID PEROXIDATION; MITOCHONDRIA; NEURONS; PEPTIDE FRAGMENTS; PEROXIDES; PPAR GAMMA; RATS; SIRTUIN 1; SUPEROXIDE DISMUTASE; TRANSCRIPTION FACTOR RELA; TRANSCRIPTION FACTORS;

EID: 84928800134     PISSN: 14491907     EISSN: None     Source Type: Journal    
DOI: 10.7150/ijms.10035     Document Type: Article

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