LRP5/6 directly bind to Frizzled and prevent Frizzled-regulated tumour metastasis

Nature Communications

Volumn 6, Issue , 2015, Pages

  Ren, Dan Ni ^a   Chen, Jinxiao ^b   Li, Zhi ^c   Yan, Hongwei ^b   Yin, Yan ^a   Wo, Da ^b   Zhang, Jiankang ^b   Ao, Luoquan ^b   Chen, Bo ^a   Ito, Takashi K ^c   Chen, Yihan ^a,b   Liu, Zhongmin ^a   Li, Yongyong ^b   Yang, Jianhua ^b   Lu, Xiaoling ^d   Peng, Yi ^d   Pan, Linghui ^d   Zhao, Yongxiang ^d   Liu, Shangfeng ^a,b   Zhu, Weidong ^a,b  

^a Tongji University   (China)

^b TONGJI UNIVERSITY SCHOOL OF MEDICINE   (China)

^c CHIBA UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^d GUANGXI MEDICAL UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

FRIZZLED PROTEIN; LOW DENSITY LIPOPROTEIN RECEPTOR RELATED PROTEIN 5; LOW DENSITY LIPOPROTEIN RECEPTOR RELATED PROTEIN 6; MEMBRANE RECEPTOR; RECOMBINANT PROTEIN; LRP5 PROTEIN, HUMAN; LRP5 PROTEIN, MOUSE; LRP6 PROTEIN, HUMAN; LRP6 PROTEIN, MOUSE;

CANCER; CHEMICAL BINDING; GENE EXPRESSION; MEMBRANE; PROTEIN; RODENT; SIGNALING; TUMOR;

ANIMAL CELL; ARTICLE; CANCER CELL; CELL MIGRATION; HUMAN; HUMAN CELL; IMMUNOPRECIPITATION; IN VITRO STUDY; IN VIVO STUDY; METASTASIS INHIBITION; MOUSE; NONHUMAN; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN INTERACTION; RECEPTOR BINDING; SIGNAL TRANSDUCTION; ANIMAL; BREAST TUMOR; CELL MOTION; GENE SILENCING; GENETICS; HEK293 CELL LINE; HEPG2 CELL LINE; METABOLISM; METASTASIS; SCID MOUSE;

ANIMALS; BREAST NEOPLASMS; CELL MOVEMENT; FRIZZLED RECEPTORS; GENE KNOCKDOWN TECHNIQUES; HEK293 CELLS; HEP G2 CELLS; HUMANS; IN VITRO TECHNIQUES; LOW DENSITY LIPOPROTEIN RECEPTOR-RELATED PROTEIN-5; LOW DENSITY LIPOPROTEIN RECEPTOR-RELATED PROTEIN-6; MICE; MICE, SCID; NEOPLASM METASTASIS;

EID: 84928799833     PISSN: None     EISSN: 20411723     Source Type: Journal    
DOI: 10.1038/ncomms7906     Document Type: Article

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