Identification of cytotoxic T lymphocyte epitopes in dengue virus serotype 1

Journal of Medical Virology

Volumn 87, Issue 7, 2015, Pages 1077-1089

  Duan, Zhiliang ^a,b   Guo, Jianglong ^a   Huang, Xi ^a,c   Liu, Huifang ^a   Chen, Xinyu ^b   Jiang, Minghua ^b   Wen, Jinsheng ^a  

^a WENZHOU MEDICAL UNIVERSITY   (China)

^b THE SECOND AFFILIATED HOSPITAL AND YUYING CHILDREN S HOSPITAL OF WENZHOU MEDICAL UNIVERSITY   (China)

^c SUN YAT SEN UNIVERSITY   (China)

Author keywords

Cytotoxic T lymphocyte; Dengue virus; Epitope

Indexed keywords

EPITOPE; GAMMA INTERFERON; NONSTRUCTURAL PROTEIN 2; NONSTRUCTURAL PROTEIN 2B; NONSTRUCTURAL PROTEIN 3; NONSTRUCTURAL PROTEIN 4A; NONSTRUCTURAL PROTEIN 4B; NONSTRUCTURAL PROTEIN 5; UNCLASSIFIED DRUG; HLA A ANTIGEN; HLA A1 ANTIGEN; HLA A2 ANTIGEN; PEPTIDE; PROTEIN BINDING;

AMINO ACID SEQUENCE; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BINDING AFFINITY; BINDING ASSAY; CONTROLLED STUDY; CYTOTOXIC T LYMPHOCYTE; DENGUE; DENGUE VIRUS 1 INFECTION; ENZYME LINKED IMMUNOSPOT ASSAY; ENZYME SPECIFICITY; HUMAN; HUMAN CELL; IMMUNOGENICITY; MONOCYTE; MOUSE; NONHUMAN; PERIPHERAL BLOOD MONONUCLEAR CELL; SPLEEN CELL; TRANSGENIC MOUSE; ANIMAL; B LYMPHOCYTE; BIOSYNTHESIS; CALLITHRIX; CHEMISTRY; CLASSIFICATION; DENGUE VIRUS; GENETICS; IMMUNOLOGY; METABOLISM; MONONUCLEAR CELL; PATHOLOGY; SEROTYPE; TRANSFORMED CELL LINE; VIROLOGY;

DENGUE VIRUS; MUS MUSCULUS;

AMINO ACID SEQUENCE; ANIMALS; B-LYMPHOCYTES; CALLITHRIX; CELL LINE, TRANSFORMED; DENGUE; DENGUE VIRUS; EPITOPES, T-LYMPHOCYTE; HLA-A ANTIGENS; HLA-A1 ANTIGEN; HLA-A2 ANTIGEN; HUMANS; INTERFERON-GAMMA; LEUKOCYTES, MONONUCLEAR; MICE; MICE, TRANSGENIC; PEPTIDES; PROTEIN BINDING; SEROGROUP; T-LYMPHOCYTES, CYTOTOXIC;

EID: 84928761749     PISSN: 01466615     EISSN: 10969071     Source Type: Journal    
DOI: 10.1002/jmv.24167     Document Type: Article

References (42)

1. al-Ramadi BK, Jelonek MT, Boyd LF, Margulies DH, Bothwell AL. 1995. Lack of strict correlation of functional sensitization with the apparent affinity of MHC/peptide complexes for the TCR. J Immunol 155:662-673.
2. An J, Zhou DS, Zhang JL, Morida H, Wang JL, Yasui K. 2004. Dengue specific CD8+ T cells have both protective and pathogenic roles in dengue virus infection. Immunol Lett 95:167-174.
3. Barber DL, Wherry EJ, Ahmed R. 2003. Cutting edge: rapid in vivo killing by memory CD8 T cells. J Immunol 171:27-31.
4. Chakraborty S, Chakravorty R, Ahmed M, Rahman A, Waise TM, Hassan F, Rahman M, Shamsuzzaman S. 2010. A computational approach for identification of epitopes in dengue virus envelope protein: a step towards designing a universal dengue vaccine targeting endemic regions. In Silico Biol 10:235-246.
5. Chan KR, Zhang SL, Tan HC, Chan YK, Chow A, Lim AP, Vasudevan SG, Hanson BJ, Ooi EE. 2011. Ligation of Fc gamma receptor 11Binhibits antibody-dependent enhancement of dengue virus infection. Proc Natl Acad Sci USA 108:12479-12484.
6. Coles RM, Mueller SN, Heath WR, Carbone FR, Brooks AG. 2002. Progression of armed CTL from draining lymph node to spleen shortly after localized infection with herpes simplex virus. J Immunol 168:834-838.
7. Dejnirattisai W, Jumnainsong A, Onsirisakul N, Fitton P, Vasanawathana S, Limpitikul W, Puttikhunt C, Edwards C, Duangchinda T, Supasa S, Chawansuntati K, Malasit P, Mongkolsapaya J, Screaton G. 2010. Cross-reacting antibodies enhance dengue virus infection in humans. Science 328:745-748.
8. Diamond MS, Harris E. 2001. Interferon inhibits dengue virus infection by preventing translation of viral RNA through a PKR-independent mechanism. Virology 289:297-311.
9. Diamond MS, Roberts TG, Edgil D, Lu B, Ernst J, Harris E. 2000. Modulation of dengue virus infection in human cells by alpha, beta, and gamma interferons. J Virol 74:4957-4966.
10. Duan ZL, Li Q, Wang ZB, Xia KD, Guo JL, Liu WQ, Wen JS. 2012. HLA-A*0201-restricted CD8+ T-cell epitopes identified in dengue viruses. Virol J 9:259.
11. Duan ZL, Wang ZB, Guo JL, Liu WQ, Hu J, Li J, Wang SN, Li Q, Wen JS. 2013. Two novel squamous cell carcinoma antigen-derived HLA-A*0201-binding peptides induce in vitro and in vivo CD8+ cytotoxic T lymphocyte responses. Int J Oncol 42:1482-1492.
12. Friberg H, Bashyam H, Toyosaki-Maeda T, Potts JA, Greenough T, Kalayanarooj S, Gibbons RV, Nisalak A, Srikiatkhachorn A, Green S, Stephens HA, Rothman AL, Mathew A. 2011. Cross-reactivity and expansion of dengue-specific T cells during acute primary and secondary infections in humans. Sci Rep 1:51.
13. Imrie A, Meeks J, Gurary A, Sukhbataar M, Kitsutani P, Effler P, Zhao Z. 2007. Differential functional avidity of dengue virus-specific T-cell clones for variant peptides representing heterologous and previously encountered serotypes. J Virol 81:10081-10091.
14. Jiang L, Wu X, Wu Y, Bai Z, Jing Q, Luo L, Dong Z, Yang Z, Xu Y, Cao Y, Di B, Wang Y, Wang M. 2013. Molecular epidemiological and virological study of dengue virus infections in Guangzhou, China, during 2001-2010. Virol J 10:4.
15. Kessler JH, Mommaas B, Mutis T, Huijbers I, Vissers D, Benckhuijsen WE, Schreuder GM, Offringa R, Goulmy E, Melief CJ, van der Burg SH, Drijfhout JW. 2003. Competition-based cellular peptide binding assays for 13 prevalent HLA class I alleles using fluorescein-labeled synthetic peptides. Hum Immunol 64:245-255.
16. Kyle JL, Beatty PR, Harris E. 2007. Dengue virus infects macrophages and dendritic cells in a mouse model of infection. J Infect Dis 195:1808-1817.
17. Li S, Peng L, Zhao W, Zhong H, Zhang F, Yan Z, Cao H. 2011. Synthetic peptides containing B- and T-cell epitope of dengue virus-2 E domain III provoked B- and T-cell responses. Vaccine 29:3695-3702.
18. Lin HE, Tsai WY, Liu IJ, Li PC, Liao MY, Tsai JJ, Wu YC, Lai CY, Lu CH, Huang JH, Chang GJ, Wu HC, Wang WK. 2012. Analysis of epitopes on dengue virus envelope protein recognized by monoclonal antibodies and polyclonal human sera by a high throughput assay. PLoS Negl Trop Dis 6:e1447.
19. Lund O, Nascimento EJ, Maciel MJr, Nielsen M, Larsen MV, Lundegaard C, Harndahl M, Lamberth K, Buus S, Salmon J, August TJ. 2011. Marques ET Jr Human leukocyte antigen (HLA) class I restricted epitope discovery in yellow fewer and dengue viruses: importance of HLA binding strength PLoS One 6:e26494.
20. Matevosyan L, Chattopadhyay S, Madelian V, Avagyan S, Nazaretyan M, Hyussian A, Vardapetyan E, Arutunyan R, Jordan F. 2011. HLA-A, HLA-B, and HLA-DRB1 allele distribution in a large Armenian population sample. Tissue Antigens 78:21-30.
21. Mathew A, Rothman AL. 2008. Understanding the contribution of cellular immunity to dengue disease pathogenesis. Immunol Rev 225:300-313.
22. Mongkolsapaya J, Dejnirattisai W, Xu XN, Vasanawathana S, Tangthawornchaikul N, Chairunsri A, Sawasdivorn S, Duangchinda T, Dong T, Rowland-Jones S, Yenchitsomanus PT, McMichael A, Malasit P, Screaton G. 2003. Original antigenic sin and apoptosis in the pathogenesis of dengue hemorrhagic fever. Nat Med 9:921-927.
23. Olsen LR, Zhang GL, Keskin DB, Reinherz EL, Brusic V. 2011. Conservation analysis of dengue virus T-cell epitope-based vaccine candidates using peptide block entropy. Front Immunol 2:69.
24. Pan QQ, Fan S, Wang XY, Pan M, Zhao X, Zhou XY, Wang CY, Shen J. 2011. The distribution of human leukocyte antigen-A, -B, and -DRB1 alleles and haplotypes based on high-resolution genotyping of 167 families from Jiangsu Province, China Hum Immunol 72:872-876.
25. Petersen J, Wurzbacher SJ, Williamson NA, Ramarathinam SH, Reid HH, Nair AK, Zhao AY, Nastovska R, Rudge G, Rossjohn J, Purcell AW. 2009. Phosphorylated self-peptides alter human leukocyte antigen class I-restricted antigen presentation and generate tumor-specific epitopes. Proc Natl Acad Sci USA 106:2776-2781.
26. Prestwood TR, May MM, Plummer EM, Morar MM, Yauch LE, Shresta S. 2012. Trafficking and replication patterns reveal splenic macrophages as major targets of dengue virus in mice. J Virol 86:12138-12147.
27. Shrestha B, Brien JD, Sukupolvi-Petty S, Austin SK, Edeling MA, Kim T, O'Brien KM, Nelson CA, Johnson S, other authors. 2010. The development of therapeutic antibodies that neutralize homologous and heterologous genotypes of dengue virus type 1. PLoS Pathog 6:e1000823.
28. Simmons CP, Dong T, Chau NV, Dung NT, Chau TN, Thao le TT, Dung NT, Hien TT, Rowland-Jones S, Farrar J. 2005. Early T-cell responses to dengue virus epitopes in Vietnamese adults with secondary dengue virus infections. J Virol 79:5665-5675.
29. Steidel M, Fragnoud R, Guillotte M, Roesch C, Michel S, Meunier T, Paranhos-Baccala G, Gervasi G, Bedin F. 2012. Nonstructural protein NS1 immunodominant epitope detected specifically in dengue virus infected material by a SELDI-TOF/MS based assay. J Med Virol 84:490-499.
30. Testa JS, Shetty V, Sinnathamby G, Nickens Z, Hafner J, Kamal S, Zhang X, Jett M, Philip R. 2012. Conserved MHC class I-presented dengue virus epitopes identified by immunoproteomics analysis are targets for cross-serotype reactive T-cell response. J Infect Dis 205:647-655.
31. Tosato G, Cohen JI. 2007. Generation of Epstein-Barr virus (EBV)-immortalized B cell lines. Curr Protoc Immunol Chapter 7, Unit 7 22.
32. van der Burg SH, Ras E, Drijfhout JW, Benckhuijsen WE, Bremers AJ, Melief CJ, Kast WM. 1995. An HLA class I peptide-binding assay based on competition for binding to class I molecules on intact human B cells identification of conserved HIV-1 polymerase peptides binding to HLA-A*0301. Hum Immunol 44:189-198.
33. van der Burg SH, Visseren MJ, Brandt RM, Kast WM, Melief CJ. 1996. Immunogenicity of peptides bound to MHC class I molecules depends on the MHC-peptide complex stability. J Immunol 156:3308-3314.
34. Villabona-Arenas CJ, Zanotto PM. 2013. Worldwide spread of dengue virus type 1. PLOS ONE 8:e62649.
35. Wahala WM, Donaldson EF, de Alwis R, Accavitti-Loper MA, Baric RS, de Silva AM. 2010. Natural strain variation and antibody neutralization of dengue serotype 3 viruses. PLoS Pathog 6:e1000821.
36. Weiskopf D, Yauch LE, Angelo MA, John DV, Greenbaum JA, Sidney J, Kolla RV, De Silva AD, de Silva AM, Grey H, Peters B, Shresta S, Sette A. 2011. Insights into HLA-restricted T cell responses in a novel mouse model of dengue virus infection point toward new implications for vaccine design. J Immunol 187:4268-4279.
37. Wen J, Duan Z, Jiang L. 2010. Identification of a dengue virus-specific HLA-A*0201-restricted CD8(+) T cell epitope. J Med Virol 82:642-648.
38. Whitehead SS, Blaney JE, Durbin AP, Murphy BR. 2007. Prospects for a dengue virus vaccine. Nat Rev Microbiol 5:518-528.
39. Wu W, Bai Z, Zhou H, Tu Z, Fang M, Tang B, Liu J, Liu L, Liu J, Chen W. 2011. Molecular epidemiology of dengue viruses in southern China from 1978 to 2006. Virol J 8:322.
40. Yauch LE, Prestwood TR, May MM, Morar MM, Zellweger RM, Peters B, Sette A, Shresta S. 2010. CD4+ T cells are not required for the induction of dengue virus-specific CD8+ T cell or antibody responses but contribute to protection after vaccination. J Immunol 185:5405-5416.
41. Yauch LE, Zellweger RM, Kotturi MF, Qutubuddin A, Sidney J, Peters B, Prestwood TR, Sette A, Shresta S. 2009. A protective role for dengue virus-specific CD8+ T cells. J Immunol 182:4865-4873.
42. Zimbwa P, Milicic A, Frater J, Scriba TJ, Willis A, Goulder PJ, Pillay T, Gunthard H, Weber JN, Zhang HT, Phillips RE. 2007. Precise identification of a human immunodeficiency virus type 1 antigen processing mutant. J Virol 81:2031-2038.