Identification of a dengue virus-specific HLA-A*0201-restricted CD8+ T cell epitope

Journal of Medical Virology

Volumn 82, Issue 4, 2010, Pages 642-648

  Wen, Jinsheng ^a,b   Duan, Zhiliang ^b   Jiang, Lifang ^a  

^a SUN YAT SEN UNIVERSITY   (China)

^b WENZHOU MEDICAL UNIVERSITY   (China)

Author keywords

CD8+ T cell epitope; Dengue virus; ELISpot; ICS; MHC peptide complex stabilization

Indexed keywords

EPITOPE; GAMMA INTERFERON; HLA A ANTIGEN;

ADULT; ARTICLE; CD8+ T LYMPHOCYTE; CELL ISOLATION; CLINICAL ARTICLE; CONTROLLED STUDY; DENGUE; DENGUE VIRUS; ENZYME LINKED IMMUNOSPOT ASSAY; FEMALE; HUMAN; HUMAN CELL; IN VITRO SELECTION; MAJOR HISTOCOMPATIBILITY COMPLEX; MALE; NONHUMAN; NUCLEOTIDE SEQUENCE; PERIPHERAL BLOOD MONONUCLEAR CELL; STAINING; VIRUS IDENTIFICATION;

ADULT; CD8-POSITIVE T-LYMPHOCYTES; CELLS, CULTURED; COMPUTATIONAL BIOLOGY; DENGUE VIRUS; EPITOPE MAPPING; EPITOPES, T-LYMPHOCYTE; FEMALE; HLA-A ANTIGENS; HUMANS; INTERFERON-GAMMA; MALE; MIDDLE AGED; YOUNG ADULT;

DENGUE VIRUS;

EID: 77949396808     PISSN: 01466615     EISSN: 10969071     Source Type: Journal    
DOI: 10.1002/jmv.21736     Document Type: Article

References (22)

1. + T cells have both protective and pathogenic roles in dengue virus infection. Immunol Lett 95:167-174.
2. Appanna R, Huat TL, See LL, Tan PL, Vadivelu J, Devi S. 2007. Cross reactive T-cell responses to the nonstructural regions of dengue viruses among dengue fever and dengue hemorrhagic fever patients in Malaysia. Clin Vaccine Immunol 14:969-977.
3. + T cells display quantitative and qualitative differences in their response to variant epitopes of heterologous viral serotypes. J Immunol 176:2817-2824.
4. Bertoletti A, Maini M, Williams R. 2003. Role of hepatitis B virus specific cytotoxic T cells in liver damage and viral control. Antiviral Res 60:61-66.
5. + human cytotoxic T lymphocytes. J Virol 63:5086-5091.
6. +-T-cell responses to human cytomegalovirus reveals broad and multispecific reactivities in healthy virus carriers. J Virol 77:5226-5240.
7. Gomez-Nunez M, Pinilla-Ibarz J, Dao T, May RJ, Pao M, Jaggi JS, Scheinberg DA. 2006. Peptide binding motif predictive algorithms correspond with experimental binding of leukemia vaccine candidate peptides to HLA-A*0201 molecules. Leuk Res 30:1293-1298.
8. Gubler DJ. 1998. Dengue and dengue hemorrhagic fever. Clin Microbiol Rev 11:480-496.
9. Hotta H, Murakami I, Miyasaki K, TakedaY, Shirane H, Hotta S. 1981. Inoculation of dengue virus into nude mice. J Gen Virol 52(Pt 1): 71-76.
10. +T-cell epitopes on hepatitis delta virus. J Gen Virol 85:3089-3098.
11. Imrie A,Meeks J, Gurary A, SukhbataarM,Kitsutani P, Effler P, Zhao Z. 2007. Differential functional avidity of dengue virus-specific T-cell clones for variant peptides representing heterologous and previously encountered serotypes. J Virol 81:10081-10091.
12. Khanna R, Burrows SR. 2000. Role of cytotoxic T lymphocytes in Epstein-Barr virus-associated diseases. Annu Rev Microbiol 54: 19-48.
13. Kuno G, Gubler DJ, Santiago de Weil NS. 1985. Antigen capture ELISA for the identification of dengue viruses. J Virol Methods 12:93-103.
14. Kurane I, Ennis FA. 1994. Cytotoxic T lymphocytes in dengue virus infection. Curr Top Microbiol Immunol 189:93-108.
15. Lanciotti RS, Calisher CH, Gubler DJ, Chang GJ, Vorndam AV. 1992. Rapid detection and typing of dengue viruses from clinical samples by using reverse transcriptase-polymerase chain reaction. J Clin Microbiol 30:545-551.
16. + cytotoxic T lymphocyte (CTL) clones. Recognition of NS3 amino acids 500 to 508 by CTL clones of two different serotype specificities. J Immunol 154:1287-1295.
17. Ohno S, Moriya O, Yoshimoto T, Hayashi H, Akatsuka T, Matsui M. 2006. Immunogenic variation between multiple HLA-A*0201-restricted, Hepatitis C Virus-derived epitopes for cytotoxic T lymphocytes. Viral Immunol 19:458-467.
18. Reche PA, Glutting JP, Reinherz EL. 2002. Prediction of MHC class I binding peptides using profile motifs. Hum Immunol 63:701-709.
19. Rothman AL. 2004. Dengue: Defining protective versus pathologic immunity. J Clin Invest 113:946-951.
20. Simmons CP, Dong T, Chau NV, Dung NT, Chau TN, Thao le TT, Dung NT, Hien TT, Rowland-Jones S, Farrar J. 2005. Early T-cell responses to dengue virus epitopes in Vietnamese adults with secondary dengue virus infections. J Virol 79:5665-5675.
21. + T-cell epitopes. Virus Res 132:42-48.
22. Xia Q, Zhou WM, Liang YH, Ge HS, Liu HS, Wang JY, Gao M, Yang S, Zhang XJ. 2006. MHC haplotypic association in Chinese Han patients with vitiligo. J Eur Acad Dermatol Venereol 20:941-946.