Dexamethasone treatment of newborn rats decreases cardiomyocyte endowment in the developing heart through epigenetic modifications

PLoS ONE

Volumn 10, Issue 4, 2015, Pages

  Gay, Maresha S ^a   Li, Yong ^a   Xiong, Fuxia ^a   Lin, Thant ^a   Zhang, Lubo ^a  

^a LOMA LINDA UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

5 AZA 2' DEOXYCYTIDINE; CYCLIN D2; DEXAMETHASONE; DNA; MIFEPRISTONE; PROTEIN P27; CCND2 PROTEIN, RAT; CDKN1B PROTEIN, RAT; CYCLIN DEPENDENT KINASE INHIBITOR 1B; GLUCOCORTICOID RECEPTOR;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CELL COUNT; CELL PROLIFERATION; CONTROLLED STUDY; DNA METHYLATION; DNA MODIFICATION; DOWN REGULATION; GENETIC REGULATION; HEART DEVELOPMENT; HEART MUSCLE CELL; NEWBORN; NONHUMAN; PROTEIN EXPRESSION; RAT; ANIMAL; BIOSYNTHESIS; CARDIAC MUSCLE CELL; DRUG EFFECTS; GENE EXPRESSION REGULATION; GENETIC EPIGENESIS; GROWTH, DEVELOPMENT AND AGING; HEART; HUMAN; METABOLISM; PATHOLOGY;

ANIMALIA; RATTUS;

ANIMALS; ANIMALS, NEWBORN; CELL PROLIFERATION; CYCLIN D2; CYCLIN-DEPENDENT KINASE INHIBITOR P27; DEXAMETHASONE; DNA METHYLATION; EPIGENESIS, GENETIC; GENE EXPRESSION REGULATION, DEVELOPMENTAL; HEART; HUMANS; MIFEPRISTONE; MYOCYTES, CARDIAC; RATS; RECEPTORS, GLUCOCORTICOID;

EID: 84928753684     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0125033     Document Type: Article

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