-
1
-
-
0033621479
-
Characterization of the Taxol binding site on the microtubul
-
Rao S, He L, Chakravarty S, Ojima I, Orr GA, Horwitz SB: Characterization of the Taxol binding site on the microtubule. Identification of Arg(282) in beta-tubulin as the site of photoincorporation of a 7-benzophenone analogue of Taxol. J Biol Chem 1999, 274:37990-37994.
-
(1999)
Identification of Arg(282) in beta-tubulin as the site of photoincorporation of a 7-benzophenone analogue of Taxol. J Biol Chem
, vol.274
, pp. 37990-37994
-
-
Rao, S.1
He, L.2
Chakravarty, S.3
Ojima, I.4
Orr, G.A.5
Horwitz, S.B.6
-
2
-
-
84884835990
-
Beyond taxol: microtubule-based treatment of disease and injury of the nervous system
-
Baas PW, Ahmad FJ: Beyond taxol: microtubule-based treatment of disease and injury of the nervous system. Brain 2013, 136:2937-2951.
-
(2013)
Brain
, vol.136
, pp. 2937-2951
-
-
Baas, P.W.1
Ahmad, F.J.2
-
4
-
-
33746665258
-
Sensory neurons and their supporting cells located in the trigeminal, thoracic and lumbar ganglia differentially express markers of injury following intravenous administration of paclitaxel in the rat
-
Jimenez-Andrade JM, Peters CM, Mejia NA, Ghilardi JR, Kuskowski MA, Mantyh PW: Sensory neurons and their supporting cells located in the trigeminal, thoracic and lumbar ganglia differentially express markers of injury following intravenous administration of paclitaxel in the rat. Neurosci Lett 2006, 405:62-67.
-
(2006)
Neurosci Lett
, vol.405
, pp. 62-67
-
-
Jimenez-Andrade, J.M.1
Peters, C.M.2
Mejia, N.A.3
Ghilardi, J.R.4
Kuskowski, M.A.5
Mantyh, P.W.6
-
5
-
-
0033970658
-
Taxol impairs anterograde axonal transport of microinjected horseradish peroxidase in dorsal root ganglia neurons in vitro
-
Theiss C, Meller K: Taxol impairs anterograde axonal transport of microinjected horseradish peroxidase in dorsal root ganglia neurons in vitro. Cell Tissue Res 2000, 299:213-224.
-
(2000)
Cell Tissue Res
, vol.299
, pp. 213-224
-
-
Theiss, C.1
Meller, K.2
-
6
-
-
33847178181
-
The MAPT H1c risk haplotype is associated with increased expression of tau and especially of 4 repeat containing transcripts
-
Myers AJ, Pittman AM, Zhao AS, Rohrer K, Kaleem M, Marlowe L, Lees A, Leung D, McKeith IG, Perry RH, Morris CM, Trojanowski JQ, Clark C, Karlawish J, Arnold S, Forman MS, Van Deerlin V, de Silva R, Hardy J: The MAPT H1c risk haplotype is associated with increased expression of tau and especially of 4 repeat containing transcripts. Neurobiol Dis 2007, 25:561-70.
-
(2007)
Neurobiol Dis
, vol.25
, pp. 561-570
-
-
Myers, A.J.1
Pittman, A.M.2
Zhao, A.S.3
Rohrer, K.4
Kaleem, M.5
Marlowe, L.6
Lees, A.7
Leung, D.8
McKeith, I.G.9
Perry, R.H.10
Morris, C.M.11
Trojanowski, J.Q.12
Clark, C.13
Karlawish, J.14
Arnold, S.15
Forman, M.S.16
Van Deerlin, V.17
de Silva, R.18
Hardy, J.19
-
7
-
-
0033041179
-
Association of an extended haplotype in the tau gene with progressive supranuclear palsy
-
Baker M, Litvan I, Houlden H, Adamson J, Dickson D, Perez-Tur J, Hardy J, Lynch T, Bigio E, Hutton M: Association of an extended haplotype in the tau gene with progressive supranuclear palsy. Human Mol Genet 1999, 8:711-715.
-
(1999)
Human Mol Genet
, vol.8
, pp. 711-715
-
-
Baker, M.1
Litvan, I.2
Houlden, H.3
Adamson, J.4
Dickson, D.5
Perez-Tur, J.6
Hardy, J.7
Lynch, T.8
Bigio, E.9
Hutton, M.10
-
8
-
-
1442304904
-
Tau haplotypes regulate transcription and are associated with Parkinson's disease
-
Kwok JB, Teber ET, Loy C, Hallupp M, Nicholson G, Mellick GD, Buchanan DD, Silburn PA, Schofield PR: Tau haplotypes regulate transcription and are associated with Parkinson's disease. Ann Neurol 2004, 55:329-334.
-
(2004)
Ann Neurol
, vol.55
, pp. 329-334
-
-
Kwok, J.B.1
Teber, E.T.2
Loy, C.3
Hallupp, M.4
Nicholson, G.5
Mellick, G.D.6
Buchanan, D.D.7
Silburn, P.A.8
Schofield, P.R.9
-
9
-
-
20444388706
-
Microtubule-associated protein tau: a marker of paclitaxel sensitivity in breast cancer
-
Rouzier R, Rajan R, Wagner P, Hess KR, Gold DL, Stec J, Ayers M, Ross JS, Zhang P, Buchholz TA, Kuerer H, Green M, Arun B, Hortobagyi GN, Symmans WF, Pusztai L: Microtubule-associated protein tau: a marker of paclitaxel sensitivity in breast cancer. Proc Natl Acad Sci USA 2005, 102:8315-20.
-
(2005)
Proc Natl Acad Sci USA
, vol.102
, pp. 8315-8320
-
-
Rouzier, R.1
Rajan, R.2
Wagner, P.3
Hess, K.R.4
Gold, D.L.5
Stec, J.6
Ayers, M.7
Ross, J.S.8
Zhang, P.9
Buchholz, T.A.10
Kuerer, H.11
Green, M.12
Arun, B.13
Hortobagyi, G.N.14
Symmans, W.F.15
Pusztai, L.16
-
10
-
-
0028675873
-
Alzheimer's disease-like phosphorylation of the microtubule-associated protein tau by glycogen synthase kinase-3 in transfected mammalian cells
-
Lovestone S, Reynolds CH, Latimer D, Davis DR, Anderton BH, Gallo JM, Hanger D, Mulot S, Marquardt B, Stabel S: Alzheimer's disease-like phosphorylation of the microtubule-associated protein tau by glycogen synthase kinase-3 in transfected mammalian cells. Current Biology 1994, 4:1077-1086.
-
(1994)
Current Biology
, vol.4
, pp. 1077-1086
-
-
Lovestone, S.1
Reynolds, C.H.2
Latimer, D.3
Davis, D.R.4
Anderton, B.H.5
Gallo, J.M.6
Hanger, D.7
Mulot, S.8
Marquardt, B.9
Stabel, S.10
-
11
-
-
80051652238
-
Overexpression of glycogen synthase kinase-3 in ovarian carcinoma cells with acquired paclitaxel resistance
-
Fu Y, Hu D, Qiu J, Xie X, Ye F, Lu WG: Overexpression of glycogen synthase kinase-3 in ovarian carcinoma cells with acquired paclitaxel resistance. Int J Gynecol Cancer 2011, 21:439-444.
-
(2011)
Int J Gynecol Cancer
, vol.21
, pp. 439-444
-
-
Fu, Y.1
Hu, D.2
Qiu, J.3
Xie, X.4
Ye, F.5
Lu, W.G.6
-
12
-
-
4444220596
-
Tau induces cooperative Taxol binding to microtubules
-
Ross JL, Santangelo CD, Makrides V, Fygenson DK: Tau induces cooperative Taxol binding to microtubules. Proc Natl Acad Sci USA 2004, 101:12910-12915.
-
(2004)
Proc Natl Acad Sci USA
, vol.101
, pp. 12910-12915
-
-
Ross, J.L.1
Santangelo, C.D.2
Makrides, V.3
Fygenson, D.K.4
-
13
-
-
0037413708
-
Repeat motifs of tau bind to the insides of microtubules in the absence of taxol
-
Kar S, Fan J, Smith MJ, Goedert M, Amos LA: Repeat motifs of tau bind to the insides of microtubules in the absence of taxol. The EMBO journal 2003, 22:70-77.
-
(2003)
The EMBO journal
, vol.22
, pp. 70-77
-
-
Kar, S.1
Fan, J.2
Smith, M.J.3
Goedert, M.4
Amos, L.A.5
-
14
-
-
34548637553
-
The Total Neuropathy Score as an assessment tool for grading the course of chemotherapy-induced peripheral neurotoxicity: comparison with the National Cancer Institute-Common Toxicity Scale
-
Cavaletti G, Frigeni B, Lanzani F, Piatti M, Rota S, Briani C, Zara G, Plasmati R, Pastorelli F, Caraceni A, Pace A, Manicone M, Lissoni A, Colombo N, Bianchi G,Zanna C, Italian NETox Group: The Total Neuropathy Score as an assessment tool for grading the course of chemotherapy-induced peripheral neurotoxicity: comparison with the National Cancer Institute-Common Toxicity Scale. J Peripher Nerv Syst 2007, 12:210-5.
-
(2007)
J Peripher Nerv Syst
, vol.12
, pp. 210-215
-
-
Cavaletti, G.1
Frigeni, B.2
Lanzani, F.3
Piatti, M.4
Rota, S.5
Briani, C.6
Zara, G.7
Plasmati, R.8
Pastorelli, F.9
Caraceni, A.10
Pace, A.11
Manicone, M.12
Lissoni, A.13
Colombo, N.14
Bianchi, G.15
Zanna, C.16
Italian N.E.Tox, Group.17
-
15
-
-
79951927821
-
Early, progressive, and sustained dysfunction of sensory axons underlies paclitaxel-induced neuropathy
-
Park SB, Lin CS, Krishnan AV, Friedlander ML, Lewis CR, Kiernan MC: Early, progressive, and sustained dysfunction of sensory axons underlies paclitaxel-induced neuropathy. Muscle Nerve 2011, 43:367-374.
-
(2011)
Muscle Nerve
, vol.43
, pp. 367-374
-
-
Park, S.B.1
Lin, C.S.2
Krishnan, A.V.3
Friedlander, M.L.4
Lewis, C.R.5
Kiernan, M.C.6
-
16
-
-
84879474820
-
CYP3A4*22 genotype and systemic exposure affect paclitaxel-induced neurotoxicity
-
de Graan AJ, Elens L, Sprowl JA, Sparreboom A, Friberg LE, van der Holt B, de Raaf PJ, de Bruijn P, Engels FK, Eskens FA, Wiemer EA, Verweij J, Mathijssen RH, van Schaik RH: CYP3A4*22 genotype and systemic exposure affect paclitaxel-induced neurotoxicity. Clin Cancer Res 2013, 19:3316-24.
-
(2013)
Clin Cancer Res
, vol.19
, pp. 3316-3324
-
-
de Graan, A.J.1
Elens, L.2
Sprowl, J.A.3
Sparreboom, A.4
Friberg, L.E.5
van der Holt, B.6
de Raaf, P.J.7
de Bruijn, P.8
Engels, F.K.9
Eskens, F.A.10
Wiemer, E.A.11
Verweij, J.12
Mathijssen, R.H.13
van Schaik, R.H.14
-
17
-
-
82255162927
-
Genetic predictors of taxane-induced neurotoxicity in a SWOG phase III intergroup adjuvant breast cancer treatment trials (S0221)
-
Sucheston LE, Zhao H, Yao S, Zirpoli G, Liu S, Barlow WE, Moore HC, Thomas Budd G, Hershman DL, Davis W, Ciupak GL, Stewart JA, Isaacs C, Hobday TJ, Salim M, Hortobagyi GN, Gralow JR, Livingston RB, Albain KS, Hayes DF, Ambrosone CB: Genetic predictors of taxane-induced neurotoxicity in a SWOG phase III intergroup adjuvant breast cancer treatment trials (S0221). Breast Cancer Res Treat 2011, 130:993-1002.
-
(2011)
Breast Cancer Res Treat
, vol.130
, pp. 993-1002
-
-
Sucheston, L.E.1
Zhao, H.2
Yao, S.3
Zirpoli, G.4
Liu, S.5
Barlow, W.E.6
Moore, H.C.7
Thomas Budd, G.8
Hershman, D.L.9
Davis, W.10
Ciupak, G.L.11
Stewart, J.A.12
Isaacs, C.13
Hobday, T.J.14
Salim, M.15
Hortobagyi, G.N.16
Gralow, J.R.17
Livingston, R.B.18
Albain, K.S.19
Hayes, D.F.20
Ambrosone, C.B.21
more..
-
18
-
-
84899708847
-
Replication of genetic polymorphisms reported to be associated with taxane-related sensory neuropathy in patients with early breast cancer treated with Paclitaxel
-
Abraham JE, Guo Q, Dorling L, Tyrer J, Ingle S, Hardy R, Vallier AL, Hiller L, Burns R, Jones L, Bowden SJ, Dunn JA, Poole CJ, Caldas C, Pharoah PP, Earl HM: Replication of genetic polymorphisms reported to be associated with taxane-related sensory neuropathy in patients with early breast cancer treated with Paclitaxel. Clin Cancer Res 2014, 20:2466-75.
-
(2014)
Clin Cancer Res
, vol.20
, pp. 2466-2475
-
-
Abraham, J.E.1
Guo, Q.2
Dorling, L.3
Tyrer, J.4
Ingle, S.5
Hardy, R.6
Vallier, A.L.7
Hiller, L.8
Burns, R.9
Jones, L.10
Bowden, S.J.11
Dunn, J.A.12
Poole, C.J.13
Caldas, C.14
Pharoah, P.P.15
Earl, H.M.16
-
19
-
-
79953052657
-
Polymorphisms in cytochromes P450 2C8 and 3A5 are associated with paclitaxel neurotoxicity
-
Leskelä S, Jara C, Leandro-García LJ, Martínez A, García-Donas J, Hernando S, Hurtado A, Vicario JC, Montero-Conde C, Landa I, López-Jiménez E, Cascón A, Milne RL, Robledo M, Rodríguez-Antona C: Polymorphisms in cytochromes P450 2C8 and 3A5 are associated with paclitaxel neurotoxicity. Pharmacogenomics J 2011, 11:121-9.
-
(2011)
Pharmacogenomics J
, vol.11
, pp. 121-129
-
-
Leskelä, S.1
Jara, C.2
Leandro-García, L.J.3
Martínez, A.4
García-Donas, J.5
Hernando, S.6
Hurtado, A.7
Vicario, J.C.8
Montero-Conde, C.9
Landa, I.10
López-Jiménez, E.11
Cascón, A.12
Milne, R.L.13
Robledo, M.14
Rodríguez-Antona, C.15
-
20
-
-
84863981895
-
CYP2C8*3 predicts benefit/risk profile in breast cancer patients receiving neoadjuvant paclitaxel
-
Hertz DL, Motsinger-Reif AA, Drobish A, Winham SJ, McLeod HL, Carey LA, Dees EC: CYP2C8*3 predicts benefit/risk profile in breast cancer patients receiving neoadjuvant paclitaxel. Breast Cancer Res Treat 2012, 134:401-410.
-
(2012)
Breast Cancer Res Treat
, vol.134
, pp. 401-410
-
-
Hertz, D.L.1
Motsinger-Reif, A.A.2
Drobish, A.3
Winham, S.J.4
McLeod, H.L.5
Carey, L.A.6
Dees, E.C.7
-
21
-
-
84872549256
-
Integration of cell line and clinical trial genome-wide analyses supports a polygenic architecture of Paclitaxelinduced sensory peripheral neuropathy
-
Wheeler HE, Gamazon ER, Wing C, Njiaju UO, Njoku C, Baldwin RM, Owzar K, Jiang C, Watson D, Shterev I, Kubo M, Zembutsu H, Winer EP, Hudis CA, Shulman LN, Nakamura Y, Ratain MJ, Kroetz DL, Cancer and Leukemia Group B, Cox NJ, Dolan ME: Integration of cell line and clinical trial genome-wide analyses supports a polygenic architecture of Paclitaxelinduced sensory peripheral neuropathy. Clin Cancer Res 2013, 19:491-9.
-
(2013)
Clin Cancer Res
, vol.19
, pp. 491-499
-
-
Wheeler, H.E.1
Gamazon, E.R.2
Wing, C.3
Njiaju, U.O.4
Njoku, C.5
Baldwin, R.M.6
Owzar, K.7
Jiang, C.8
Watson, D.9
Shterev, I.10
Kubo, M.11
Zembutsu, H.12
Winer, E.P.13
Hudis, C.A.14
Shulman, L.N.15
Nakamura, Y.16
Ratain, M.J.17
Kroetz, D.L.18
Cox, N.J.19
Dolan, M.E.20
more..
-
22
-
-
84866415102
-
A genome-wide association study identifies novel loci for paclitaxelinduced sensory peripheral neuropathy in CALGB 40101
-
Baldwin RM, Owzar K, Zembutsu H, Chhibber A, Kubo M, Jiang C, Watson D, Eclov RJ, Mefford J, McLeod HL, Friedman PN, Hudis CA, Winer EP, Jorgenson EM, Witte JS, Shulman LN, Nakamura Y, Ratain MJ, Kroetz DL: A genome-wide association study identifies novel loci for paclitaxelinduced sensory peripheral neuropathy in CALGB 40101. Clin Cancer Res 2012, 18:5099-109.
-
(2012)
Clin Cancer Res
, vol.18
, pp. 5099-5109
-
-
Baldwin, R.M.1
Owzar, K.2
Zembutsu, H.3
Chhibber, A.4
Kubo, M.5
Jiang, C.6
Watson, D.7
Eclov, R.J.8
Mefford, J.9
McLeod, H.L.10
Friedman, P.N.11
Hudis, C.A.12
Winer, E.P.13
Jorgenson, E.M.14
Witte, J.S.15
Shulman, L.N.16
Nakamura, Y.17
Ratain, M.J.18
Kroetz, D.L.19
-
23
-
-
84883172515
-
Genome-wide association study identifies ephrin type A receptors implicated in paclitaxel induced peripheral sensory neuropathy
-
Leandro-García LJ, Inglada-Pérez L, Pita G, Hjerpe E, Leskelä S, Jara C, Mielgo X, González-Neira A, Robledo M, Avall-Lundqvist E, Gréen H, Rodríguez-Antona C: Genome-wide association study identifies ephrin type A receptors implicated in paclitaxel induced peripheral sensory neuropathy. J Med Genet 2013, 50:599-605.
-
(2013)
J Med Genet
, vol.50
, pp. 599-605
-
-
Leandro-García, L.J.1
Inglada-Pérez, L.2
Pita, G.3
Hjerpe, E.4
Leskelä, S.5
Jara, C.6
Mielgo, X.7
González-Neira, A.8
Robledo, M.9
Avall-Lundqvist, E.10
Gréen, H.11
Rodríguez-Antona, C.12
-
24
-
-
84886417617
-
Cumulative genetic risk predicts platinum/taxane-induced neurotoxicity
-
McWhinney-Glass S, Winham SJ, Hertz DL, Yen Revollo J, Paul J, He Y, Brown R, Motsinger-Reif AA, McLeod HL, Scottish Gynaecological Clinical Trials Group: Cumulative genetic risk predicts platinum/taxane-induced neurotoxicity. Clin Cancer Res 2013, 19:5769-76.
-
(2013)
Clin Cancer Res
, vol.19
, pp. 5769-5776
-
-
McWhinney-Glass, S.1
Winham, S.J.2
Hertz, D.L.3
Yen Revollo, J.4
Paul, J.5
He, Y.6
Brown, R.7
Motsinger-Reif, A.A.8
McLeod, H.L.9
Scottish Gynaecological Clinical Trials, Group.10
-
25
-
-
84865077921
-
Regulatory polymorphisms in ß-tubulin IIa are associated with paclitaxel-induced peripheral neuropathy
-
Leandro-García LJ, Leskelä S, Jara C, Gréen H, Avall-Lundqvist E, Wheeler HE, Dolan ME, Inglada-Perez L, Maliszewska A, de Cubas AA, Comino-Méndez I, Mancikova V, Cascón A, Robledo M, Rodríguez-Antona C: Regulatory polymorphisms in ß-tubulin IIa are associated with paclitaxel-induced peripheral neuropathy. Clin Cancer Res 2012, 18:4441-8.
-
(2012)
Clin Cancer Res
, vol.18
, pp. 4441-4448
-
-
Leandro-García, L.J.1
Leskelä, S.2
Jara, C.3
Gréen, H.4
Avall-Lundqvist, E.5
Wheeler, H.E.6
Dolan, M.E.7
Inglada-Perez, L.8
Maliszewska, A.9
de Cubas, A.A.10
Comino-Méndez, I.11
Mancikova, V.12
Cascón, A.13
Robledo, M.14
Rodríguez-Antona, C.15
-
26
-
-
42549102569
-
Protein abundance of class III beta-tubulin but not Delta2-alpha-tubulin or tau is related to paclitaxel response in carcinomas of unknown primary site
-
Sève P, Reiman T, Isaac S, Trillet-Lenoir V, Lafanechere L, Sawyer M, Dumontet C: Protein abundance of class III beta-tubulin but not Delta2-alpha-tubulin or tau is related to paclitaxel response in carcinomas of unknown primary site. Anticancer Res 2008, 28:1161-1167.
-
(2008)
Anticancer Res
, vol.28
, pp. 1161-1167
-
-
Sève, P.1
Reiman, T.2
Isaac, S.3
Trillet-Lenoir, V.4
Lafanechere, L.5
Sawyer, M.6
Dumontet, C.7
-
27
-
-
55849090651
-
Glycogen synthase kinase-3beta and tau genes interact in Alzheimer's disease
-
Kwok JB, Loy CT, Hamilton G, Lau E, Hallupp M, Williams J, Owen MJ, Broe GA, Tang N, Lam L, Powell JF, Lovestone S, Schofield PR: Glycogen synthase kinase-3beta and tau genes interact in Alzheimer's disease. Ann Neurol 2008, 64:446-454.
-
(2008)
Ann Neurol
, vol.64
, pp. 446-454
-
-
Kwok, J.B.1
Loy, C.T.2
Hamilton, G.3
Lau, E.4
Hallupp, M.5
Williams, J.6
Owen, M.J.7
Broe, G.A.8
Tang, N.9
Lam, L.10
Powell, J.F.11
Lovestone, S.12
Schofield, P.R.13
-
28
-
-
28544435240
-
GSK3B polymorphisms alter transcription and splicing in Parkinson's disease
-
Kwok JB, Hallupp M, Loy CT, Chan DK, Woo J, Mellick GD, Buchanan DD, Silburn PA, Halliday GM, Schofield PR: GSK3B polymorphisms alter transcription and splicing in Parkinson's disease. Ann Neurol 2005, 58:829-839.
-
(2005)
Ann Neurol
, vol.58
, pp. 829-839
-
-
Kwok, J.B.1
Hallupp, M.2
Loy, C.T.3
Chan, D.K.4
Woo, J.5
Mellick, G.D.6
Buchanan, D.D.7
Silburn, P.A.8
Halliday, G.M.9
Schofield, P.R.10
-
29
-
-
0034731461
-
Glycogen synthase kinase-3beta phosphorylates protein tau and rescues the axonopathy in the central nervous system of human four-repeat tau transgenic mice
-
Spittaels K, Van den Haute C, Van Dorpe J, Geerts H, Mercken M, Bruynseels K, Lasrado R, Vandezande K, Laenen I, Boon T, Van Lint J, Vandenheede J, Moechars D, Loos R, Van Leuven F: Glycogen synthase kinase-3beta phosphorylates protein tau and rescues the axonopathy in the central nervous system of human four-repeat tau transgenic mice. J Biol Chem 2000, 275:41340-9.
-
(2000)
J Biol Chem
, vol.275
, pp. 41340-41349
-
-
Spittaels, K.1
Van den Haute, C.2
Van Dorpe, J.3
Geerts, H.4
Mercken, M.5
Bruynseels, K.6
Lasrado, R.7
Vandezande, K.8
Laenen, I.9
Boon, T.10
Van Lint, J.11
Vandenheede, J.12
Moechars, D.13
Loos, R.14
Van Leuven, F.15
-
30
-
-
77952546195
-
GSK3: a possible link between beta amyloid peptide and tau protein
-
Hernandez F, Gomez de Barreda E, Fuster-Matanzo A, Lucas JJ, Avila J: GSK3: a possible link between beta amyloid peptide and tau protein. Exp Neurol 2010, 223:322-325.
-
(2010)
Exp Neurol
, vol.223
, pp. 322-325
-
-
Hernandez, F.1
Gomez de Barreda, E.2
Fuster-Matanzo, A.3
Lucas, J.J.4
Avila, J.5
|