Rho Kinase Pathway Alterations in the Brain and Leukocytes in Huntington’s Disease

Molecular Neurobiology

Volumn 53, Issue 4, 2016, Pages 2132-2140

  Narayanan, K Lakshmi ^a   Chopra, Vanita ^a   Rosas, H Diana ^a   Malarick, Keith ^a   Hersch, Steven ^a  

^a MASSACHUSETTS GENERAL HOSPITAL   (United States)

Author keywords

Biomarker; Huntington s disease; mRNA expression; Rho kinase pathway

Indexed keywords

BIOLOGICAL MARKER; COFILIN 1; LIM KINASE 1; RHO KINASE; RHOA GUANINE NUCLEOTIDE BINDING PROTEIN; ACTIN DEPOLYMERIZING FACTOR; PROFILIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BLOOD ANALYSIS; BRAIN TISSUE; COFILIN 1 GENE; CONTROLLED STUDY; DISEASE ASSOCIATION; DOWN REGULATION; ENZYME INHIBITION; ENZYME LOCALIZATION; GENE; GENE EXPRESSION REGULATION; HUMAN; HUMAN TISSUE; HUNTINGTON CHOREA; LEUKOCYTE; LIMK1 GENE; MALE; MOUSE; MYPT1 GENE; NONHUMAN; PRK2 GENE; PROFILIN 1 GENE; PROTEIN TARGETING; REAL TIME POLYMERASE CHAIN REACTION; RHOA GENE; ROCK1 GENE; SIGNAL TRANSDUCTION; TRANSGENIC MOUSE; UPREGULATION; WESTERN BLOTTING; ADULT; AGED; ANIMAL; BLOOD; BRAIN; C57BL MOUSE; DISEASE MODEL; ENZYMOLOGY; FEMALE; FRONTAL LOBE; GENETICS; METABOLISM; MIDDLE AGED; PATHOLOGY; POSTMORTEM CHANGE;

ACTIN DEPOLYMERIZING FACTORS; ADULT; AGED; ANIMALS; BLOTTING, WESTERN; BRAIN; DISEASE MODELS, ANIMAL; FEMALE; FRONTAL LOBE; GENE EXPRESSION REGULATION; HUMANS; HUNTINGTON DISEASE; LEUKOCYTES; MALE; MICE, INBRED C57BL; MICE, TRANSGENIC; MIDDLE AGED; POSTMORTEM CHANGES; PROFILINS; RHO-ASSOCIATED KINASES; SIGNAL TRANSDUCTION;

EID: 84928710726     PISSN: 08937648     EISSN: 15591182     Source Type: Journal    
DOI: 10.1007/s12035-015-9147-9     Document Type: Article

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