Abscisic acid acts as a blocker of the bitter taste G protein-coupled receptor T2R4

Biochemistry

Volumn 54, Issue 16, 2015, Pages 2622-2631

  Pydi, Sai P ^a   Jaggupilli, Appalaraju ^a   Nelson, Ken M ^c   Abrams, Suzanne R ^c   Bhullar, Rajinder P ^a   Loewen, Michele C ^b,c   Chelikani, Prashen ^a  

^a UNIVERSITY OF MANITOBA   (Canada)

^b NATIONAL RESEARCH COUNCIL CANADA   (Canada)

^c UNIVERSITY OF SASKATCHEWAN   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACIDS; HISTOLOGY; MOLECULAR MODELING; NEUROPHYSIOLOGY; PROTEINS; RESPIRATORY SYSTEM; TISSUE;

CENTRAL NERVOUS SYSTEMS; FUNCTIONAL ASSAYS; G PROTEIN COUPLED RECEPTORS; GAMMA-AMINOBUTYRIC ACIDS; MOLECULAR PATHWAYS; REPRODUCTIVE SYSTEMS; SITE DIRECTED MUTAGENESIS; STRUCTURE FUNCTIONS;

FORESTRY;

ABSCISIC ACID; G PROTEIN COUPLED RECEPTOR; G PROTEIN COUPLED RECEPTOR T2R4; UNCLASSIFIED DRUG; CAROTENOID; SESQUITERPENE; TASTE RECEPTORS, TYPE 2; XANTHOXIN; YOHIMBINE;

ARTICLE; BITTER TASTE; CALCIUM CELL LEVEL; CALCIUM MOBILIZATION; CALCIUM TRANSPORT; CELL COMMUNICATION; CONTROLLED STUDY; DRUG BINDING; HUMAN; HUMAN CELL; IC50; MAMMAL CELL; MOLECULAR DOCKING; MOLECULAR MODEL; MUTATIONAL ANALYSIS; PREDICTION; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; SITE DIRECTED MUTAGENESIS; AGONISTS; ANTAGONISTS AND INHIBITORS; BINDING SITE; CHEMICAL STRUCTURE; CHEMISTRY; GENETICS; METABOLISM; PHYSIOLOGY; STRUCTURE ACTIVITY RELATION; TASTE;

ABSCISIC ACID; BINDING SITES; CAROTENOIDS; HUMANS; MODELS, MOLECULAR; MUTAGENESIS, SITE-DIRECTED; RECEPTORS, G-PROTEIN-COUPLED; SESQUITERPENES; STRUCTURE-ACTIVITY RELATIONSHIP; TASTE PERCEPTION; YOHIMBINE;

EID: 84928653437     PISSN: 00062960     EISSN: 15204995     Source Type: Journal    
DOI: 10.1021/acs.biochem.5b00265     Document Type: Article

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