-
1
-
-
0042021703
-
Ocular melanoma: A review and the relationship to cutaneous melanoma
-
Hursi, E. A.; Harbour, J. W.; Cornelius, L. A. Ocular melanoma: A review and the relationship to cutaneous melanoma. Arch. Dermatol. 139:1067-1073;2003
-
(2003)
Arch. Dermatol.
, vol.139
, pp. 1067-1073
-
-
Hursi, E.A.1
Harbour, J.W.2
Cornelius, L.A.3
-
2
-
-
39149104690
-
Mela-analysis of phase II cooperative group trials in metastatic stage IV melanoma to determine progression-free and overall survival benchmarks Cor future Phase II trials
-
Korn, E. L.; Liu, P. Y; Lee, S. J.; Chapman, J. A.; Niedzwiccki, D.; Suman, V. J.; Moon, J.; Sondak, V. K.; Atkins, M. B.; Eisenhauer, E. A.; Parulekar, W.; Markovic, S. N.; Saxman, S.; Kirkwood, J. M. Mela-analysis of phase II cooperative group trials in metastatic stage IV melanoma to determine progression-free and overall survival benchmarks Cor future Phase II trials. J. Clin. Oncol. 26:527-534; 2008.
-
(2008)
J. Clin. Oncol.
, vol.26
, pp. 527-534
-
-
Korn, E.L.1
Liu, P.Y.2
Lee, S.J.3
Chapman, J.A.4
Niedzwiccki, D.5
Suman, V.J.6
Moon, J.7
Sondak, V.K.8
Atkins, M.B.9
Eisenhauer, E.A.10
Parulekar, W.11
Markovic, S.N.12
Saxman, S.13
Kirkwood, J.M.14
-
3
-
-
79959795786
-
Improved survival with vemurafenib in melanoma with BRAF V600E mutation
-
Chapman, P. B.; Hauschild, A.; Robert, C; Haanen, J. B.; Ascierto, P.; Larkin, J.; Dummer, R.; Garbe, C; Testori, A.; Maio, M.; Hogg, D.; Lorigan, P.; Lebbe, C; Jouary, T.; Schadendorf, D.; Ribas, A.; O'Day, S. J.; Sosman, J. A.; Kirkwood, J. M.; Eggermont, A. M.; Drcno, B.; Nolop, K.; Li, J.; Nelson, B.; Hou, J.; Lee, R. J.; Flaherty, K. T.; McArthur, G. A. Improved survival with vemurafenib in melanoma with BRAF V600E mutation. N. Engl. J. Med. 364:2507-2516;2011.
-
(2011)
N. Engl. J. Med.
, vol.364
, pp. 2507-2516
-
-
Chapman, P.B.1
Hauschild, A.2
Robert, C.3
Haanen, J.B.4
Ascierto, P.5
Larkin, J.6
Dummer, R.7
Garbe, C.8
Testori, A.9
Maio, M.10
Hogg, D.11
Lorigan, P.12
Lebbe, C.13
Jouary, T.14
Schadendorf, D.15
Ribas, A.16
O'Day, S.J.17
Sosman, J.A.18
Kirkwood, J.M.19
Eggermont, A.M.20
Drcno, B.21
Nolop, K.22
Li, J.23
Nelson, B.24
Hou, J.25
Lee, R.J.26
Flaherty, K.T.27
McArthur, G.A.28
more..
-
4
-
-
77954801079
-
Improved survival with ipilimumab in patients with metastatic melanoma
-
Hodi, F. S.; O'Day, S. J.; McDermott, D. E; Weber, R. W.; Sosman, J. A.; Haanen, J. B.; Gonzalez, R.; Robert, C; Schadendorf, D.; Hassel, J. C; Akerlcy, W.; Van Den Ecrtwegh, A. J.; Lulzky, J.; Lorigan, P.; Vaubel, J. M.; Linette, G. P.; Hogg, D.; Ottensmeier, C. H.; Lebbe, C; Peschcl, C; Quirt, I.; Clark, J. I.; Wolchok, J. D.; Weber, J. S.; Tian, J.; Yellin, M. J.; Nichol, G. M.; Hoos, A.; Urba, W. J. Improved survival with ipilimumab in patients with metastatic melanoma. N. Engl. J. Med. 363:711-723; 2010.
-
(2010)
N. Engl. J. Med.
, vol.363
, pp. 711-723
-
-
Hodi, F.S.1
O'Day, S.J.2
McDermott, D.E.3
Weber, R.W.4
Sosman, J.A.5
Haanen, J.B.6
Gonzalez, R.7
Robert, C.8
Schadendorf, D.9
Hassel, J.C.10
Akerlcy, W.11
Van Den Ecrtwegh, A.J.12
Lulzky, J.13
Lorigan, P.14
Vaubel, J.M.15
Linette, G.P.16
Hogg, D.17
Ottensmeier, C.H.18
Lebbe, C.19
Peschcl, C.20
Quirt, I.21
Clark, J.I.22
Wolchok, J.D.23
Weber, J.S.24
Tian, J.25
Yellin, M.J.26
Nichol, G.M.27
Hoos, A.28
Urba, W.J.29
more..
-
5
-
-
33750466230
-
Introduction to NF-κB: Players, pathways, perspectives
-
Gilmore, T. D. Introduction to NF-κB: Players, pathways, perspectives. Oncogene 25:6680-6684;2006.
-
(2006)
Oncogene
, vol.25
, pp. 6680-6684
-
-
Gilmore, T.D.1
-
6
-
-
77950929562
-
Melanoma: A model for testing new agents in combination therapies
-
Arl. 38
-
Ascierto, P. A.; Streicher, H. Z.; Sznol, M. Melanoma: A model for testing new agents in combination therapies. J. Transl. Med. 8(Arl. 38):1-7; 2010.
-
(2010)
J. Transl. Med.
, vol.8
, pp. 1-7
-
-
Ascierto, P.A.1
Streicher, H.Z.2
Sznol, M.3
-
7
-
-
1442356717
-
NF-κB in the vascular progression of melanoma
-
Kashani-Sabet, M.; Shaikh, L.; Miller, 3rd, J. R.; Nosrati, M.; Ferreira, C. M.; Debs, R. J.; Sagebiel, R. W. NF-κB in the vascular progression of melanoma. J. Clin. Oncol. 22:617-623; 2004.
-
(2004)
J. Clin. Oncol.
, vol.22
, pp. 617-623
-
-
Kashani-Sabet, M.1
Shaikh, L.2
Miller, J.R.3
Nosrati, M.4
Ferreira, C.M.5
Debs, R.J.6
Sagebiel, R.W.7
-
8
-
-
0033843211
-
Level of interleukin-8 expression by metastatic human melanoma cells directly correlates with constitutive NF-κB activity
-
Huang, S.; De Guzman, A.; Bucana, C. D.; Fidler, I. J. Level of interleukin-8 expression by metastatic human melanoma cells directly correlates with constitutive NF-κB activity. Cytokines Cell. Mol. Ther. 6:9-17; 2000.
-
(2000)
Cytokines Cell. Mol. Ther.
, vol.6
, pp. 9-17
-
-
Huang, S.1
De Guzman, A.2
Bucana, C.D.3
Fidler, I.J.4
-
9
-
-
0036270898
-
The role of chemokines in melanoma tumor growth and metastasis
-
Payne, A. S.; Cornelius, L. A. The role of chemokines in melanoma tumor growth and metastasis. J. Invest. Dermatol. 118:915-922; 2002.
-
(2002)
J. Invest. Dermatol.
, vol.118
, pp. 915-922
-
-
Payne, A.S.1
Cornelius, L.A.2
-
10
-
-
0036717195
-
NF-κB, chemokinc gene transcription and tumour growth
-
Richmond, A. NF-κB, chemokinc gene transcription and tumour growth. Nat. Rev. Immunol. 2:664-674; 2002.
-
(2002)
Nat. Rev. Immunol.
, vol.2
, pp. 664-674
-
-
Richmond, A.1
-
11
-
-
33947527353
-
Oncogenic BRAF regulates p-Trcp expression and NF-κB activity in human melanoma cells
-
Liu, J.; Surcsh Kumar, K. G.; Yu, D.; Mollon, S. A.; McMahon, M.: Herlyn, M.; Thomas-Tikhonenko, A.; Fuchs, S. Y. Oncogenic BRAF regulates p-Trcp expression and NF-κB activity in human melanoma cells. Oncogene 26:1954-1958:2007.
-
(2007)
Oncogene
, vol.26
, pp. 1954-1958
-
-
Liu, J.1
Surcsh Kumar, K.G.2
Yu, D.3
Mollon, S.A.4
McMahon, M.5
Herlyn, M.6
Thomas-Tikhonenko, A.7
Fuchs, S.Y.8
-
12
-
-
0037040901
-
A novel NF-κB-inducing kinase-MAPK signaling pathway up-regulates NF-κB activity in melanoma cells
-
Dhawan, P.; Richmond, A. A novel NF-κB-inducing kinase-MAPK signaling pathway up-regulates NF-κB activity in melanoma cells. J. Biol. Chem. 277:7920-7928;2002.
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 7920-7928
-
-
Dhawan, P.1
Richmond, A.2
-
13
-
-
84874389242
-
Pentoxifylline and the proleasomc inhibitor MG132 induce apoplosis in human leukemia U937 cells through a decrease in the expression of Bcl-2 and Bcl-XL and phosphorylation of p65..1
-
Bravo-Cuellar, A.; Hcrnandez-Flores, G.; Lerma-Diaz, J. M.; Dominguez-Rodriguez, J. R.; Jave-Suarez, L. F.; De Celis-Carrillo, R.; Aguilar-Lemarroy, A.; Gomez-Lomeli, P.; Ortiz-Lazareno, P. C. Pentoxifylline and the proleasomc inhibitor MG132 induce apoplosis in human leukemia U937 cells through a decrease in the expression of Bcl-2 and Bcl-XL and phosphorylation of p65..1. Biomed. Sci. 20(Art. 13):113; 2013.
-
(2013)
Biomed. Sci.
, vol.20
, pp. 113
-
-
Bravo-Cuellar, A.1
Hcrnandez-Flores, G.2
Lerma-Diaz, J.M.3
Dominguez-Rodriguez, J.R.4
Jave-Suarez, L.F.5
De Celis-Carrillo, R.6
Aguilar-Lemarroy, A.7
Gomez-Lomeli, P.8
Ortiz-Lazareno, P.C.9
-
14
-
-
84876260453
-
An evidence-based review of obatoclax mesylate in the treatment of hematological malignancies
-
Goard, C. A.; Schimmcr, A. D. An evidence-based review of obatoclax mesylate in the treatment of hematological malignancies. Core Evid. 8:15-26; 2013.
-
(2013)
Core Evid.
, vol.8
, pp. 15-26
-
-
Goard, C.A.1
Schimmcr, A.D.2
-
15
-
-
0034178264
-
Synthesis of NF-κB activation inhibitors derived from epoxyquinomicin C
-
Matsumoto, N.; Ariga, A.; To-E, S.; Nakamura, H.; Agata, N.; Hirano, S.; Inoue, J.; Umezawa, K. Synthesis of NF-κB activation inhibitors derived from epoxyquinomicin C. Bioorg. Med. Chem. Lett. 10:865-869; 2000.
-
(2000)
Bioorg. Med. Chem. Lett.
, vol.10
, pp. 865-869
-
-
Matsumoto, N.1
Ariga, A.2
To-E, S.3
Nakamura, H.4
Agata, N.5
Hirano, S.6
Inoue, J.7
Umezawa, K.8
-
16
-
-
52949115652
-
Identification of the RelA domain responsible for action of a new NF-κB inhibitor DHMEQ
-
Walanabe, M.; Nakashima, M.; Togano, T.; Higashihara, M.; Walanabe, T.; Umezawa, K.; Hone, R. Identification of the RelA domain responsible for action of a new NF-κB inhibitor DHMEQ. Biochem. Biophys. Res. Commun. 376:310-314; 2008.
-
(2008)
Biochem. Biophys. Res. Commun.
, vol.376
, pp. 310-314
-
-
Walanabe, M.1
Nakashima, M.2
Togano, T.3
Higashihara, M.4
Walanabe, T.5
Umezawa, K.6
Hone, R.7
-
17
-
-
52449131840
-
Inaclivation of NF-κB components by covaleni binding of (-)-dehydroxymelhylepoxyc|uinomicin to specific cysteine residues
-
Yamamoto, M.; Horie, R.; Takeiri, M.; Kozawa, I.; Umezawa, K. Inaclivation of NF-κB components by covaleni binding of (-)-dehydroxymelhylepoxyc|uinomicin to specific cysteine residues. J. Med. Chem. 51:5780-5788;2008.
-
(2008)
J. Med. Chem.
, vol.51
, pp. 5780-5788
-
-
Yamamoto, M.1
Horie, R.2
Takeiri, M.3
Kozawa, I.4
Umezawa, K.5
-
18
-
-
0026876577
-
Cytogenetic studies of human malignant melanoma cell lines
-
Yin, M.; Yoshida, M. A.; Tonomura, A.; Kasuga, T. Cytogenetic studies of human malignant melanoma cell lines. Bull. Tokyo Med. Dent. Univ. 39:43-54; 1992.
-
(1992)
Bull. Tokyo Med. Dent. Univ.
, vol.39
, pp. 43-54
-
-
Yin, M.1
Yoshida, M.A.2
Tonomura, A.3
Kasuga, T.4
-
19
-
-
0025730640
-
A rapid micropreparalion technique for extraction of DNA-binding proteins from limiting numbers of mammalian cells
-
Andrews, N. C; Faller, D. V. A rapid micropreparalion technique for extraction of DNA-binding proteins from limiting numbers of mammalian cells. Nucleic Acids Res. 19(9):2499;1991.
-
(1991)
Nucleic Acids Res.
, vol.19
, Issue.9
, pp. 2499
-
-
Andrews, N.C.1
Faller, D.V.2
-
20
-
-
85047695761
-
Ligand-independenl signaling by overexpressed CD30 drives NF-κB activation in Hodgkin-Reed-Sternberg cells
-
Horie, R.; Watanabe, T; Morishita, Y; Ito, K.; Ishida, T.; Kanegac, Y; Saito, I.; Higashihara, M.; Mori, S.; Kadin. M. E. Ligand-independenl signaling by overexpressed CD30 drives NF-κB activation in Hodgkin-Reed-Sternberg cells. Oncogene 21:2493-2503;2002.
-
(2002)
Oncogene
, vol.21
, pp. 2493-2503
-
-
Horie, R.1
Watanabe, T.2
Morishita, Y.3
Ito, K.4
Ishida, T.5
Kanegac, Y.6
Saito, I.7
Higashihara, M.8
Mori, S.9
Kadin, M.E.10
-
21
-
-
0021118703
-
Quantitative analysis of dose-effect relationships: The combined effects of multiple drugs or enzyme inhibitors
-
Chou, T C; Talalay, P. Quantitative analysis of dose-effect relationships: The combined effects of multiple drugs or enzyme inhibitors. Adv. Enzyme Regul. 22:27-55; 1984.
-
(1984)
Adv. Enzyme Regul.
, vol.22
, pp. 27-55
-
-
Chou, T.C.1
Talalay, P.2
-
22
-
-
36749092771
-
Lnlerferon-alpha induces transient upregulalion of c-FLIP through NF-κB activation
-
Kanetaka, Y; Hayashida, M.; Hoshika, A.; Yanase. N.; Mizuguchi, J. lnlerferon-alpha induces transient upregulalion of c-FLIP through NF-κB activation. Exp. Cell Res. 314:246-254:2008.
-
(2008)
Exp. Cell Res.
, vol.314
, pp. 246-254
-
-
Kanetaka, Y.1
Hayashida, M.2
Hoshika, A.3
Yanase, N.4
Mizuguchi, J.5
-
23
-
-
1842525717
-
Comparative expression of NFκB proteins in melanocytes of normal skin vs benign intradermal naevus and human metastatic melanoma biopsies
-
McNully, S. E.; Del Rosario, R.; Cen, D.; Meyskens, Jr., F. L.; Yang, S. Comparative expression of NFκB proteins in melanocytes of normal skin vs. benign intradermal naevus and human metastatic melanoma biopsies. Pigment Cell. Res. I 7:173-180; 2004.
-
(2004)
Pigment Cell. Res. I
, vol.7
, pp. 173-180
-
-
McNully, S.E.1
Del Rosario, R.2
Cen, D.3
Meyskens, F.L.4
Yang, S.5
-
24
-
-
34648847350
-
Cureumin downregulates the constitutive activity of NF-κB and induces apoptosis in novel mouse melanoma cells
-
Marin, Y. E.; Wall, B. A.; Wang, S.; Namkoong, J.; Marlino, J. J.; Suh, J.; Lee, H. J.; Rabson, A. B.; Yang, C. S.; Chen, S.; Ryu, J. H. Cureumin downregulates the constitutive activity of NF-κB and induces apoptosis in novel mouse melanoma cells. Melanoma Res. 17:274-283; 2007.
-
(2007)
Melanoma Res.
, vol.17
, pp. 274-283
-
-
Marin, Y.E.1
Wall, B.A.2
Wang, S.3
Namkoong, J.4
Marlino, J.J.5
Suh, J.6
Lee, H.J.7
Rabson, A.B.8
Yang, C.S.9
Chen, S.10
Ryu, J.H.11
-
25
-
-
77949541721
-
NF-κB inhibition through proteasome inhibition or IKKβ blockade increases the susceptibility of melanoma cells to cytostatic treatment through distinct pathways
-
Amschler, K.; Schon, M. P.; Pletz, N.; Wallbrecht, K.; Erpenbeck, L.; Schon, M. NF-κB inhibition through proteasome inhibition or IKKβ blockade increases the susceptibility of melanoma cells to cytostatic treatment through distinct pathways. J. Invest. Dermatol. 130:1073-1086;2010.
-
(2010)
J. Invest. Dermatol.
, vol.130
, pp. 1073-1086
-
-
Amschler, K.1
Schon, M.P.2
Pletz, N.3
Wallbrecht, K.4
Erpenbeck, L.5
Schon, M.6
-
26
-
-
32944468414
-
BMS-345541 targets inhibitor of κB kinase and induces apoptosis in melanoma: Involvement of nuclear factor \κB and mitochondria pathways
-
Yang, J.; Amiri, K. I.; Burke, J. R.; Schmid, J. A.; Richmond, A. BMS-345541 targets inhibitor of κB kinase and induces apoptosis in melanoma: Involvement of nuclear factor \κB and mitochondria pathways. Clin. Cancer Res. 12:950-960; 2006.
-
(2006)
Clin. Cancer Res.
, vol.12
, pp. 950-960
-
-
Yang, J.1
Amiri, K.I.2
Burke, J.R.3
Schmid, J.A.4
Richmond, A.5
-
27
-
-
84856213846
-
The diverse and complex roles of NF-κB subunits in cancer
-
Perkins, N. D. The diverse and complex roles of NF-κB subunits in cancer. Nat. Rev. Cancer 12:121-132; 2012.
-
(2012)
Nat. Rev. Cancer
, vol.12
, pp. 121-132
-
-
Perkins, N.D.1
-
28
-
-
68749103771
-
The NF-κB-independent functions of IKK subunits in immunity and cancer
-
Chariot, A. The NF-κB-independent functions of IKK subunits in immunity and cancer. Trends Cell Biol. 19:404-413; 2009.
-
(2009)
Trends Cell Biol.
, vol.19
, pp. 404-413
-
-
Chariot, A.1
-
29
-
-
77951239640
-
Characterizing the involvement of the nuclear factor-kappa B (NFκB) transcription factor in uveal melanoma. Invest
-
Dror, R.; Lederman, M.; Umezawa, K.; Barak, V.; Pe'er, J.; Chowcrs, I. Characterizing the involvement of the nuclear factor-kappa B (NFκB) transcription factor in uveal melanoma. Invest. Ophthalmol. Vis. Sci. 51:1811-1816;2010.
-
(2010)
Ophthalmol. Vis. Sci.
, vol.51
, pp. 1811-1816
-
-
Dror, R.1
Lederman, M.2
Umezawa, K.3
Barak, V.4
Pe'er, J.5
Chowcrs, I.6
-
30
-
-
80052066352
-
Role of NF-κB/Snail/RKIP loop in the response of tumor cells to photodynamic therapy
-
Rapozzi, V.; Umczawa, K.; Xodo, L. E. Role of NF-κB/Snail/RKIP loop in the response of tumor cells to photodynamic therapy. Lasers Surg. Med. 43:575-585; 2011.
-
(2011)
Lasers Surg. Med.
, vol.43
, pp. 575-585
-
-
Rapozzi, V.1
Umczawa, K.2
Xodo, L.E.3
-
31
-
-
33947526496
-
IκBα independent induction of NF-κB and its inhibition by DHMEQ in Hodgkin/Reed-Sternberg cells
-
Walanabe, M.; Dewan, M. Z.; Taira, M.; Shoda, M.; Honda, M.; Sata, T; Higashihara, M.; Kadin, M. E.; Watanabe, T; Yamamolo, N.; Umezawa, K.; Horic, R. IκBα independent induction of NF-κB and its inhibition by DHMEQ in Hodgkin/Reed-Sternberg cells. Lab. Invest. 87:372-382; 2007.
-
(2007)
Lab. Invest.
, vol.87
, pp. 372-382
-
-
Walanabe, M.1
Dewan, M.Z.2
Taira, M.3
Shoda, M.4
Honda, M.5
Sata, T.6
Higashihara, M.7
Kadin, M.E.8
Watanabe, T.9
Yamamolo, N.10
Umezawa, K.11
Horic, R.12
|