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Volumn 376, Issue 2, 2008, Pages 310-314

Identification of the RelA domain responsible for action of a new NF-κB inhibitor DHMEQ

Author keywords

DHMEQ; NF B inhibitor; p50; RelA

Indexed keywords

CYSTEINE; DEHYDROXYMETHYLEPOXYQUINOMICIN; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; PROTEIN P50; PROTEIN P52; TRANSCRIPTION FACTOR RELA; TRANSCRIPTION FACTOR RELB;

EID: 52949115652     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2008.08.148     Document Type: Article
Times cited : (33)

References (18)
  • 2
    • 33750466230 scopus 로고    scopus 로고
    • Introduction to NF-κB: players, pathways, perspectives
    • Gilmore T.D. Introduction to NF-κB: players, pathways, perspectives. Oncogene 25 (2006) 6680-6684
    • (2006) Oncogene , vol.25 , pp. 6680-6684
    • Gilmore, T.D.1
  • 3
    • 33750432183 scopus 로고    scopus 로고
    • Nuclear factor-κB and inhibitor of κB kinase pathways in oncogenic initiation and progression
    • Basseres D.S., and Baldwin A.S. Nuclear factor-κB and inhibitor of κB kinase pathways in oncogenic initiation and progression. Oncogene 25 (2006) 6817-6830
    • (2006) Oncogene , vol.25 , pp. 6817-6830
    • Basseres, D.S.1    Baldwin, A.S.2
  • 4
    • 33748311907 scopus 로고    scopus 로고
    • Inhibition of tumor growth by NF-κB inhibitors
    • Umezawa K. Inhibition of tumor growth by NF-κB inhibitors. Cancer Sci. 97 (2006) 990-995
    • (2006) Cancer Sci. , vol.97 , pp. 990-995
    • Umezawa, K.1
  • 5
    • 0037025347 scopus 로고    scopus 로고
    • Inhibition of tumor necrosis factor-α-induced nuclear translocation and activation of NF-κB by dehydroxymethylepoxyquinomicin
    • Ariga A., Namekawa J., Matsumoto N., Inoue J., and Umezawa K. Inhibition of tumor necrosis factor-α-induced nuclear translocation and activation of NF-κB by dehydroxymethylepoxyquinomicin. J. Biol. Chem. 277 (2002) 24625-24630
    • (2002) J. Biol. Chem. , vol.277 , pp. 24625-24630
    • Ariga, A.1    Namekawa, J.2    Matsumoto, N.3    Inoue, J.4    Umezawa, K.5
  • 8
    • 0025888264 scopus 로고
    • Efficient site-directed mutagenesis using uracil-containing DNA
    • Kunkel T.A., Bebenek K., and McClary J. Efficient site-directed mutagenesis using uracil-containing DNA. Methods Enzymol. 204 (1991) 125-139
    • (1991) Methods Enzymol. , vol.204 , pp. 125-139
    • Kunkel, T.A.1    Bebenek, K.2    McClary, J.3
  • 9
    • 0023806075 scopus 로고
    • Single-step purification of polypeptides expressed in Escherichia coli as fusions with glutathione S-transferase
    • Smith D.B., and Johnson K.S. Single-step purification of polypeptides expressed in Escherichia coli as fusions with glutathione S-transferase. Gene 67 (1988) 31-40
    • (1988) Gene , vol.67 , pp. 31-40
    • Smith, D.B.1    Johnson, K.S.2
  • 10
    • 33750448661 scopus 로고    scopus 로고
    • Transcriptional regulation via the NF-κB signaling module
    • Hoffmann A., Natoli G., and Ghosh G. Transcriptional regulation via the NF-κB signaling module. Oncogene 25 (2006) 6706-6716
    • (2006) Oncogene , vol.25 , pp. 6706-6716
    • Hoffmann, A.1    Natoli, G.2    Ghosh, G.3
  • 11
    • 0031897457 scopus 로고    scopus 로고
    • The N-terminal domain of IκBα masks the nuclear localization signal(s) of p50 and c-Rel homodimers
    • Latimer M., Ernst M.K., Dunn L.L., Drutskaya M., and Rice N.R. The N-terminal domain of IκBα masks the nuclear localization signal(s) of p50 and c-Rel homodimers. Mol. Cell. Biol. 18 (1998) 2640-2649
    • (1998) Mol. Cell. Biol. , vol.18 , pp. 2640-2649
    • Latimer, M.1    Ernst, M.K.2    Dunn, L.L.3    Drutskaya, M.4    Rice, N.R.5
  • 12
    • 15444363021 scopus 로고    scopus 로고
    • DNA binding of repressor nuclear factor-κB p50/p50 depends on phosphorylation of Ser337 by the protein kinase A catalytic subunit
    • Guan H., Hou S., and Ricciardi R.P. DNA binding of repressor nuclear factor-κB p50/p50 depends on phosphorylation of Ser337 by the protein kinase A catalytic subunit. J. Biol. Chem. 280 (2005) 9957-9962
    • (2005) J. Biol. Chem. , vol.280 , pp. 9957-9962
    • Guan, H.1    Hou, S.2    Ricciardi, R.P.3
  • 13
    • 12944273470 scopus 로고    scopus 로고
    • Targeting of nuclear factor κB Pathways by dehydroxymethylepoxyquinomicin, a novel inhibitor of breast carcinomas: antitumor and antiangiogenic potential in vivo
    • Matsumoto G., Namekawa J., Muta M., Nakamura T., Bando H., Tohyama K., Toi M., and Umezawa K. Targeting of nuclear factor κB Pathways by dehydroxymethylepoxyquinomicin, a novel inhibitor of breast carcinomas: antitumor and antiangiogenic potential in vivo. Clin. Cancer Res. 11 (2005) 1287-1293
    • (2005) Clin. Cancer Res. , vol.11 , pp. 1287-1293
    • Matsumoto, G.1    Namekawa, J.2    Muta, M.3    Nakamura, T.4    Bando, H.5    Tohyama, K.6    Toi, M.7    Umezawa, K.8
  • 14
    • 33749265867 scopus 로고    scopus 로고
    • The alternative NF-κB pathway from biochemistry to biology: pitfalls and promises for future drug development
    • Dejardin E. The alternative NF-κB pathway from biochemistry to biology: pitfalls and promises for future drug development. Biochem. Pharmacol. 72 (2006) 1161-1179
    • (2006) Biochem. Pharmacol. , vol.72 , pp. 1161-1179
    • Dejardin, E.1
  • 16
    • 2942618506 scopus 로고    scopus 로고
    • Role of cysteine residues of p65/NF-κB on the inhibition by the sesquiterpene lactone parthenolide and N-ethyl maleimide, and on its transactivating potential
    • Garcia-Pineres A.J., Lindenmeyer M.T., and Merfort I. Role of cysteine residues of p65/NF-κB on the inhibition by the sesquiterpene lactone parthenolide and N-ethyl maleimide, and on its transactivating potential. Life Sci. 75 (2004) 841-856
    • (2004) Life Sci. , vol.75 , pp. 841-856
    • Garcia-Pineres, A.J.1    Lindenmeyer, M.T.2    Merfort, I.3
  • 17
    • 39049178095 scopus 로고    scopus 로고
    • The synthetic epoxyquinoids jesterone dimer and epoxyquinone A monomer induce apoptosis and inhibit REL (human c-Rel) DNA binding in an IκBα-deficient diffuse large B-cell lymphoma cell line
    • Liang M.C., Bardhan S., Porco Jr. J.A., and Gilmore T.D. The synthetic epoxyquinoids jesterone dimer and epoxyquinone A monomer induce apoptosis and inhibit REL (human c-Rel) DNA binding in an IκBα-deficient diffuse large B-cell lymphoma cell line. Cancer Lett. 241 (2006) 69-78
    • (2006) Cancer Lett. , vol.241 , pp. 69-78
    • Liang, M.C.1    Bardhan, S.2    Porco Jr., J.A.3    Gilmore, T.D.4
  • 18
    • 0344549859 scopus 로고    scopus 로고
    • Regulation of RelA subcellular localization by a putative nuclear export signal and p50
    • Harhaj E.W., and Sun S.C. Regulation of RelA subcellular localization by a putative nuclear export signal and p50. Mol. Cell. Biol. 19 (1999) 7088-7095
    • (1999) Mol. Cell. Biol. , vol.19 , pp. 7088-7095
    • Harhaj, E.W.1    Sun, S.C.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.