-
1
-
-
0034178264
-
Synthesis of NF-κB activation inhibitors derived from epoxyquinomicin C
-
Matsumoto N., Ariga A., To-e S., Nakamura H., Agata N., Hirano S., Inoue J., and Umezawa K. Synthesis of NF-κB activation inhibitors derived from epoxyquinomicin C. Bioorg. Med. Chem. Lett. 10 (2000) 865-869
-
(2000)
Bioorg. Med. Chem. Lett.
, vol.10
, pp. 865-869
-
-
Matsumoto, N.1
Ariga, A.2
To-e, S.3
Nakamura, H.4
Agata, N.5
Hirano, S.6
Inoue, J.7
Umezawa, K.8
-
2
-
-
33750466230
-
Introduction to NF-κB: players, pathways, perspectives
-
Gilmore T.D. Introduction to NF-κB: players, pathways, perspectives. Oncogene 25 (2006) 6680-6684
-
(2006)
Oncogene
, vol.25
, pp. 6680-6684
-
-
Gilmore, T.D.1
-
3
-
-
33750432183
-
Nuclear factor-κB and inhibitor of κB kinase pathways in oncogenic initiation and progression
-
Basseres D.S., and Baldwin A.S. Nuclear factor-κB and inhibitor of κB kinase pathways in oncogenic initiation and progression. Oncogene 25 (2006) 6817-6830
-
(2006)
Oncogene
, vol.25
, pp. 6817-6830
-
-
Basseres, D.S.1
Baldwin, A.S.2
-
4
-
-
33748311907
-
Inhibition of tumor growth by NF-κB inhibitors
-
Umezawa K. Inhibition of tumor growth by NF-κB inhibitors. Cancer Sci. 97 (2006) 990-995
-
(2006)
Cancer Sci.
, vol.97
, pp. 990-995
-
-
Umezawa, K.1
-
5
-
-
0037025347
-
Inhibition of tumor necrosis factor-α-induced nuclear translocation and activation of NF-κB by dehydroxymethylepoxyquinomicin
-
Ariga A., Namekawa J., Matsumoto N., Inoue J., and Umezawa K. Inhibition of tumor necrosis factor-α-induced nuclear translocation and activation of NF-κB by dehydroxymethylepoxyquinomicin. J. Biol. Chem. 277 (2002) 24625-24630
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 24625-24630
-
-
Ariga, A.1
Namekawa, J.2
Matsumoto, N.3
Inoue, J.4
Umezawa, K.5
-
6
-
-
13244252299
-
A novel NF-κB inhibitor DHMEQ selectively targets constitutive NF-κB activity and induces apoptosis of multiple myeloma cells in vitro and in vivo
-
Watanabe M., Dewan M.Z., Okamura T., Sasaki M., Itoh K., Higashihara M., Mizoguchi H., Honda M., Sata T., Watanabe T., Yamamoto N., Umezawa K., and Horie R. A novel NF-κB inhibitor DHMEQ selectively targets constitutive NF-κB activity and induces apoptosis of multiple myeloma cells in vitro and in vivo. Int. J. Cancer 114 (2005) 32-38
-
(2005)
Int. J. Cancer
, vol.114
, pp. 32-38
-
-
Watanabe, M.1
Dewan, M.Z.2
Okamura, T.3
Sasaki, M.4
Itoh, K.5
Higashihara, M.6
Mizoguchi, H.7
Honda, M.8
Sata, T.9
Watanabe, T.10
Yamamoto, N.11
Umezawa, K.12
Horie, R.13
-
7
-
-
27144476790
-
Dual targeting of transformed and untransformed HTLV-1-infected T cells by DHMEQ, a potent and selective inhibitor of NF-κB, as a strategy for chemoprevention and therapy of adult T-cell leukemia
-
Watanabe M., Ohsugi T., Shoda M., Ishida T., Aizawa S., Maruyama-Nagai M., Utsunomiya A., Koga S., Yamada Y., Kamihira S., Okayama A., Kikuchi H., Uozumi K., Yamaguchi K., Higashihara M., Umezawa K., Watanabe T., and Horie R. Dual targeting of transformed and untransformed HTLV-1-infected T cells by DHMEQ, a potent and selective inhibitor of NF-κB, as a strategy for chemoprevention and therapy of adult T-cell leukemia. Blood 106 (2005) 2462-2471
-
(2005)
Blood
, vol.106
, pp. 2462-2471
-
-
Watanabe, M.1
Ohsugi, T.2
Shoda, M.3
Ishida, T.4
Aizawa, S.5
Maruyama-Nagai, M.6
Utsunomiya, A.7
Koga, S.8
Yamada, Y.9
Kamihira, S.10
Okayama, A.11
Kikuchi, H.12
Uozumi, K.13
Yamaguchi, K.14
Higashihara, M.15
Umezawa, K.16
Watanabe, T.17
Horie, R.18
-
8
-
-
0025888264
-
Efficient site-directed mutagenesis using uracil-containing DNA
-
Kunkel T.A., Bebenek K., and McClary J. Efficient site-directed mutagenesis using uracil-containing DNA. Methods Enzymol. 204 (1991) 125-139
-
(1991)
Methods Enzymol.
, vol.204
, pp. 125-139
-
-
Kunkel, T.A.1
Bebenek, K.2
McClary, J.3
-
9
-
-
0023806075
-
Single-step purification of polypeptides expressed in Escherichia coli as fusions with glutathione S-transferase
-
Smith D.B., and Johnson K.S. Single-step purification of polypeptides expressed in Escherichia coli as fusions with glutathione S-transferase. Gene 67 (1988) 31-40
-
(1988)
Gene
, vol.67
, pp. 31-40
-
-
Smith, D.B.1
Johnson, K.S.2
-
10
-
-
33750448661
-
Transcriptional regulation via the NF-κB signaling module
-
Hoffmann A., Natoli G., and Ghosh G. Transcriptional regulation via the NF-κB signaling module. Oncogene 25 (2006) 6706-6716
-
(2006)
Oncogene
, vol.25
, pp. 6706-6716
-
-
Hoffmann, A.1
Natoli, G.2
Ghosh, G.3
-
11
-
-
0031897457
-
The N-terminal domain of IκBα masks the nuclear localization signal(s) of p50 and c-Rel homodimers
-
Latimer M., Ernst M.K., Dunn L.L., Drutskaya M., and Rice N.R. The N-terminal domain of IκBα masks the nuclear localization signal(s) of p50 and c-Rel homodimers. Mol. Cell. Biol. 18 (1998) 2640-2649
-
(1998)
Mol. Cell. Biol.
, vol.18
, pp. 2640-2649
-
-
Latimer, M.1
Ernst, M.K.2
Dunn, L.L.3
Drutskaya, M.4
Rice, N.R.5
-
12
-
-
15444363021
-
DNA binding of repressor nuclear factor-κB p50/p50 depends on phosphorylation of Ser337 by the protein kinase A catalytic subunit
-
Guan H., Hou S., and Ricciardi R.P. DNA binding of repressor nuclear factor-κB p50/p50 depends on phosphorylation of Ser337 by the protein kinase A catalytic subunit. J. Biol. Chem. 280 (2005) 9957-9962
-
(2005)
J. Biol. Chem.
, vol.280
, pp. 9957-9962
-
-
Guan, H.1
Hou, S.2
Ricciardi, R.P.3
-
13
-
-
12944273470
-
Targeting of nuclear factor κB Pathways by dehydroxymethylepoxyquinomicin, a novel inhibitor of breast carcinomas: antitumor and antiangiogenic potential in vivo
-
Matsumoto G., Namekawa J., Muta M., Nakamura T., Bando H., Tohyama K., Toi M., and Umezawa K. Targeting of nuclear factor κB Pathways by dehydroxymethylepoxyquinomicin, a novel inhibitor of breast carcinomas: antitumor and antiangiogenic potential in vivo. Clin. Cancer Res. 11 (2005) 1287-1293
-
(2005)
Clin. Cancer Res.
, vol.11
, pp. 1287-1293
-
-
Matsumoto, G.1
Namekawa, J.2
Muta, M.3
Nakamura, T.4
Bando, H.5
Tohyama, K.6
Toi, M.7
Umezawa, K.8
-
14
-
-
33749265867
-
The alternative NF-κB pathway from biochemistry to biology: pitfalls and promises for future drug development
-
Dejardin E. The alternative NF-κB pathway from biochemistry to biology: pitfalls and promises for future drug development. Biochem. Pharmacol. 72 (2006) 1161-1179
-
(2006)
Biochem. Pharmacol.
, vol.72
, pp. 1161-1179
-
-
Dejardin, E.1
-
15
-
-
0035955729
-
Cysteine 38 in p65/NF-κB plays a crucial role in DNA binding inhibition by sesquiterpene lactones
-
Garcia-Pineres A.J., Castro V., Mora G., Schmidt T.J., Strunck E., Pahl H.L., and Merfort I. Cysteine 38 in p65/NF-κB plays a crucial role in DNA binding inhibition by sesquiterpene lactones. J. Biol. Chem. 276 (2001) 39713-39720
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 39713-39720
-
-
Garcia-Pineres, A.J.1
Castro, V.2
Mora, G.3
Schmidt, T.J.4
Strunck, E.5
Pahl, H.L.6
Merfort, I.7
-
16
-
-
2942618506
-
Role of cysteine residues of p65/NF-κB on the inhibition by the sesquiterpene lactone parthenolide and N-ethyl maleimide, and on its transactivating potential
-
Garcia-Pineres A.J., Lindenmeyer M.T., and Merfort I. Role of cysteine residues of p65/NF-κB on the inhibition by the sesquiterpene lactone parthenolide and N-ethyl maleimide, and on its transactivating potential. Life Sci. 75 (2004) 841-856
-
(2004)
Life Sci.
, vol.75
, pp. 841-856
-
-
Garcia-Pineres, A.J.1
Lindenmeyer, M.T.2
Merfort, I.3
-
17
-
-
39049178095
-
The synthetic epoxyquinoids jesterone dimer and epoxyquinone A monomer induce apoptosis and inhibit REL (human c-Rel) DNA binding in an IκBα-deficient diffuse large B-cell lymphoma cell line
-
Liang M.C., Bardhan S., Porco Jr. J.A., and Gilmore T.D. The synthetic epoxyquinoids jesterone dimer and epoxyquinone A monomer induce apoptosis and inhibit REL (human c-Rel) DNA binding in an IκBα-deficient diffuse large B-cell lymphoma cell line. Cancer Lett. 241 (2006) 69-78
-
(2006)
Cancer Lett.
, vol.241
, pp. 69-78
-
-
Liang, M.C.1
Bardhan, S.2
Porco Jr., J.A.3
Gilmore, T.D.4
-
18
-
-
0344549859
-
Regulation of RelA subcellular localization by a putative nuclear export signal and p50
-
Harhaj E.W., and Sun S.C. Regulation of RelA subcellular localization by a putative nuclear export signal and p50. Mol. Cell. Biol. 19 (1999) 7088-7095
-
(1999)
Mol. Cell. Biol.
, vol.19
, pp. 7088-7095
-
-
Harhaj, E.W.1
Sun, S.C.2
|