-
1
-
-
41449086790
-
Cardiac plasticity
-
Hill J.A., Olson E.N. Cardiac plasticity. N. Engl. J. Med. 2008, 358:1370-1380. 10.1056/NEJMra072139.
-
(2008)
N. Engl. J. Med.
, vol.358
, pp. 1370-1380
-
-
Hill, J.A.1
Olson, E.N.2
-
2
-
-
0347444723
-
MicroRNAs: genomics, biogenesis, mechanism, and function
-
Bartel D.P. MicroRNAs: genomics, biogenesis, mechanism, and function. Cell 2004, 116:281-297. 10.1016/S0092-8674(04)00045-5.
-
(2004)
Cell
, vol.116
, pp. 281-297
-
-
Bartel, D.P.1
-
3
-
-
0141843656
-
The nuclear RNase III Drosha initiates microRNA processing
-
Lee Y., Ahn C., Han J., Choi H., Kim J., Yim J., Lee J., Provost P., Rådmark O., Kim S., Kim V.N. The nuclear RNase III Drosha initiates microRNA processing. Nature 2003, 425:415-419. 10.1038/nature01957.
-
(2003)
Nature
, vol.425
, pp. 415-419
-
-
Lee, Y.1
Ahn, C.2
Han, J.3
Choi, H.4
Kim, J.5
Yim, J.6
Lee, J.7
Provost, P.8
Rådmark, O.9
Kim, S.10
Kim, V.N.11
-
4
-
-
9144225636
-
The Microprocessor complex mediates the genesis of microRNAs
-
Gregory R.I., Yan K.P., Amuthan G., Chendrimada T., Doratotaj B., Cooch N., Shiekhattar R. The Microprocessor complex mediates the genesis of microRNAs. Nature 2004, 432:235-240. 10.1038/nature03049.
-
(2004)
Nature
, vol.432
, pp. 235-240
-
-
Gregory, R.I.1
Yan, K.P.2
Amuthan, G.3
Chendrimada, T.4
Doratotaj, B.5
Cooch, N.6
Shiekhattar, R.7
-
5
-
-
84861944845
-
BRCA1 regulates microRNA biogenesis via the DROSHA microprocessor complex
-
Kawai S., Amano A. BRCA1 regulates microRNA biogenesis via the DROSHA microprocessor complex. J. Cell Biol. 2012, 197:201-208. 10.1083/jcb.201110008.
-
(2012)
J. Cell Biol.
, vol.197
, pp. 201-208
-
-
Kawai, S.1
Amano, A.2
-
6
-
-
79960185923
-
Dicer recognizes the 5' end of RNA for efficient and accurate processing
-
Park J.E., Heo I., Tian Y., Simanshu D.K., Chang H., Jee D., Patel D.J., Kim V.N. Dicer recognizes the 5' end of RNA for efficient and accurate processing. Nature 2011, 475:201-205. 10.1038/nature10198.
-
(2011)
Nature
, vol.475
, pp. 201-205
-
-
Park, J.E.1
Heo, I.2
Tian, Y.3
Simanshu, D.K.4
Chang, H.5
Jee, D.6
Patel, D.J.7
Kim, V.N.8
-
7
-
-
34547115237
-
Human TRBP and PACT directly interact with each other and associate with Dicer to facilitate the production of small interfering RNA
-
(rna.283207[pii])
-
Kok K.H., Ng M.H., Ching Y.P., Jin D.Y. Human TRBP and PACT directly interact with each other and associate with Dicer to facilitate the production of small interfering RNA. J. Biol. Chem. 2007, 282:17649-17657. (doi:rna.283207[pii].10.1261/rna.283207).
-
(2007)
J. Biol. Chem.
, vol.282
, pp. 17649-17657
-
-
Kok, K.H.1
Ng, M.H.2
Ching, Y.P.3
Jin, D.Y.4
-
8
-
-
23644433363
-
TRBP recruits the Dicer complex to Ago2 for microRNA processing and gene silencing
-
Chendrimada T.P., Gregory R.I., Kumaraswamy E., Norman J., Cooch N., Nishikura K., Shiekhattar R. TRBP recruits the Dicer complex to Ago2 for microRNA processing and gene silencing. Nature 2005, 436:740-744. 10.1038/nature03868.
-
(2005)
Nature
, vol.436
, pp. 740-744
-
-
Chendrimada, T.P.1
Gregory, R.I.2
Kumaraswamy, E.3
Norman, J.4
Cooch, N.5
Nishikura, K.6
Shiekhattar, R.7
-
10
-
-
84856751210
-
Developing microRNA therapeutics
-
van Rooij E., Purcell A.L., Levin A.A. Developing microRNA therapeutics. Circ. Res. 2012, 110:496-507. 10.1161/CIRCRESAHA.111.247916.
-
(2012)
Circ. Res.
, vol.110
, pp. 496-507
-
-
van Rooij, E.1
Purcell, A.L.2
Levin, A.A.3
-
11
-
-
84891848945
-
MicroRNA therapeutics in cardiovascular disease models
-
Dangwal S., Thum T. microRNA therapeutics in cardiovascular disease models. Annu. Rev. Pharmacol. Toxicol. 2014, 54:185-203. 10.1146/annurev-pharmtox-011613-135957.
-
(2014)
Annu. Rev. Pharmacol. Toxicol.
, vol.54
, pp. 185-203
-
-
Dangwal, S.1
Thum, T.2
-
12
-
-
84899658554
-
MicroRNAs in cardiovascular diseases: current knowledge and the road ahead
-
Condorelli G., Latronico M.V., Cavarretta E. microRNAs in cardiovascular diseases: current knowledge and the road ahead. J. Am. Coll. Cardiol. 2014, 63:2177-2187. 10.1016/j.jacc.2014.01.050.
-
(2014)
J. Am. Coll. Cardiol.
, vol.63
, pp. 2177-2187
-
-
Condorelli, G.1
Latronico, M.V.2
Cavarretta, E.3
-
13
-
-
57749168828
-
MicroRNA-21 contributes to myocardial disease by stimulating MAP kinase signalling in fibroblasts
-
Thum T., Gross C., Fiedler J., Fischer T., Kissler S., Bussen M., Galuppo P., Just S., Rottbauer W., Frantz S., Castoldi M., Soutschek J., Koteliansky V., Rosenwald A., Basson M.A., Licht J.D., Pena J.T., Rouhanifard S.H., Muckenthaler M.U., Tuschl T., Martin G.R., Bauersachs J., Engelhardt S. MicroRNA-21 contributes to myocardial disease by stimulating MAP kinase signalling in fibroblasts. Nature 2008, 456:980-984. 10.1038/nature07511.
-
(2008)
Nature
, vol.456
, pp. 980-984
-
-
Thum, T.1
Gross, C.2
Fiedler, J.3
Fischer, T.4
Kissler, S.5
Bussen, M.6
Galuppo, P.7
Just, S.8
Rottbauer, W.9
Frantz, S.10
Castoldi, M.11
Soutschek, J.12
Koteliansky, V.13
Rosenwald, A.14
Basson, M.A.15
Licht, J.D.16
Pena, J.T.17
Rouhanifard, S.H.18
Muckenthaler, M.U.19
Tuschl, T.20
Martin, G.R.21
Bauersachs, J.22
Engelhardt, S.23
more..
-
14
-
-
84857972864
-
Non-cardiomyocyte microRNAs in heart failure
-
Tijsen A.J., Pinto Y.M., Creemers E.E. Non-cardiomyocyte microRNAs in heart failure. Cardiovasc. Res. 2012, 93:573-582. 10.1093/cvr/cvr344.
-
(2012)
Cardiovasc. Res.
, vol.93
, pp. 573-582
-
-
Tijsen, A.J.1
Pinto, Y.M.2
Creemers, E.E.3
-
15
-
-
84870915950
-
BAMBI (BMP and activin membrane-bound inhibitor) protects the murine heart from pressure-overload biomechanical stress by restraining TGF-β signaling
-
Villar A.V., García R., Llano M., Cobo M., Merino D., Lantero A., Tramullas M., Hurlé J.M., Hurlé M.A., Nistal J.F. BAMBI (BMP and activin membrane-bound inhibitor) protects the murine heart from pressure-overload biomechanical stress by restraining TGF-β signaling. Biochim. Biophys. Acta Mol. Basis Dis. 2013, 1832:323-335. 10.1016/j.bbadis.2012.11.007.
-
(2013)
Biochim. Biophys. Acta Mol. Basis Dis.
, vol.1832
, pp. 323-335
-
-
Villar, A.V.1
García, R.2
Llano, M.3
Cobo, M.4
Merino, D.5
Lantero, A.6
Tramullas, M.7
Hurlé, J.M.8
Hurlé, M.A.9
Nistal, J.F.10
-
16
-
-
84899128394
-
Cardiac fibroblast-derived microRNA passenger strand-enriched exosomes mediate cardiomyocyte hypertrophy
-
Bang C., Batkai S., Dangwal S., Gupta S.K., Foinquinos A., Holzmann A., Just A., Remke J., Zimmer K., Zeug A., Ponimaskin E., Schmiedl A., Yin X., Mayr M., Halder R., Fischer A., Engelhardt S., Wei Y., Schober A., Fiedler J., Thum T. Cardiac fibroblast-derived microRNA passenger strand-enriched exosomes mediate cardiomyocyte hypertrophy. J. Clin. Invest. 2014, 124:2136-2146. 10.1172/JCI70577.
-
(2014)
J. Clin. Invest.
, vol.124
, pp. 2136-2146
-
-
Bang, C.1
Batkai, S.2
Dangwal, S.3
Gupta, S.K.4
Foinquinos, A.5
Holzmann, A.6
Just, A.7
Remke, J.8
Zimmer, K.9
Zeug, A.10
Ponimaskin, E.11
Schmiedl, A.12
Yin, X.13
Mayr, M.14
Halder, R.15
Fischer, A.16
Engelhardt, S.17
Wei, Y.18
Schober, A.19
Fiedler, J.20
Thum, T.21
more..
-
17
-
-
80052819014
-
Transforming growth factor (TGF)-β signaling in cardiac remodeling
-
Dobaczewski M., Chen W., Frangogiannis N.G. Transforming growth factor (TGF)-β signaling in cardiac remodeling. J. Mol. Cell. Cardiol. 2011, 51:600-606. 10.1016/j.yjmcc.2010.10.033.
-
(2011)
J. Mol. Cell. Cardiol.
, vol.51
, pp. 600-606
-
-
Dobaczewski, M.1
Chen, W.2
Frangogiannis, N.G.3
-
18
-
-
78751507979
-
Molecular mechanisms that control interstitial fibrosis in the pressure-overloaded heart
-
Creemers E.E., Pinto Y.M. Molecular mechanisms that control interstitial fibrosis in the pressure-overloaded heart. Cardiovasc. Res. 2011, 89:265-272. 10.1093/cvr/cvq308.
-
(2011)
Cardiovasc. Res.
, vol.89
, pp. 265-272
-
-
Creemers, E.E.1
Pinto, Y.M.2
-
19
-
-
77955373730
-
MiR-21 mediates fibrogenic activation of pulmonary fibroblasts and lung fibrosis
-
Liu G., Friggeri A., Yang Y., Milosevic J., Ding Q., Thannickal V.J., Kaminski N., Abraham E. miR-21 mediates fibrogenic activation of pulmonary fibroblasts and lung fibrosis. J. Exp. Med. 2010, 207:1589-1597. 10.1084/jem.20100035.
-
(2010)
J. Exp. Med.
, vol.207
, pp. 1589-1597
-
-
Liu, G.1
Friggeri, A.2
Yang, Y.3
Milosevic, J.4
Ding, Q.5
Thannickal, V.J.6
Kaminski, N.7
Abraham, E.8
-
20
-
-
80052316668
-
Smad3-mediated upregulation of miR-21 promotes renal fibrosis
-
Zhong X., Chung A.C., Chen H.Y., Meng X.M., Lan H.Y. Smad3-mediated upregulation of miR-21 promotes renal fibrosis. J. Am. Soc. Nephrol. 2011, 22:1668-1681. 10.1681/ASN.2010111168.
-
(2011)
J. Am. Soc. Nephrol.
, vol.22
, pp. 1668-1681
-
-
Zhong, X.1
Chung, A.C.2
Chen, H.Y.3
Meng, X.M.4
Lan, H.Y.5
-
21
-
-
84880316996
-
MicroRNA-21 in scleroderma fibrosis and its function in TGF-β-regulated fibrosis-related genes expression
-
Zhu H., Luo H., Li Y., Zhou Y., Zhou Y., Jiang Y., Chai J., Xiao X., You Y., Zuo X. MicroRNA-21 in scleroderma fibrosis and its function in TGF-β-regulated fibrosis-related genes expression. J. Clin. Immunol. 2013, 33:1100-1109. 10.1007/s10875-013-9896-z.
-
(2013)
J. Clin. Immunol.
, vol.33
, pp. 1100-1109
-
-
Zhu, H.1
Luo, H.2
Li, Y.3
Zhou, Y.4
Zhou, Y.5
Jiang, Y.6
Chai, J.7
Xiao, X.8
You, Y.9
Zuo, X.10
-
22
-
-
84882771252
-
Myocardial and circulating levels of microRNA-21 reflect left ventricular fibrosis in aortic stenosis patients
-
Villar A.V., García R., Merino D., Llano M., Cobo M., Montalvo C., Martín-Durán R., Hurlé M.A., Nistal J.F. Myocardial and circulating levels of microRNA-21 reflect left ventricular fibrosis in aortic stenosis patients. Int. J. Cardiol. 2013, 167:2875-2878. 10.1016/j.ijcard.2012.07.021.
-
(2013)
Int. J. Cardiol.
, vol.167
, pp. 2875-2878
-
-
Villar, A.V.1
García, R.2
Merino, D.3
Llano, M.4
Cobo, M.5
Montalvo, C.6
Martín-Durán, R.7
Hurlé, M.A.8
Nistal, J.F.9
-
23
-
-
46449128469
-
SMAD proteins control DROSHA-mediated microRNA maturation
-
Davis B.N., Hilyard A.C., Lagna G., Hata A. SMAD proteins control DROSHA-mediated microRNA maturation. Nature 2008, 454:56-61. 10.1038/nature07086.
-
(2008)
Nature
, vol.454
, pp. 56-61
-
-
Davis, B.N.1
Hilyard, A.C.2
Lagna, G.3
Hata, A.4
-
24
-
-
77955484492
-
Smad proteins bind a conserved RNA sequence to promote microRNA maturation by Drosha
-
Davis B.N., Hilyard A.C., Nguyen P.H., Lagna G., Hata A. Smad proteins bind a conserved RNA sequence to promote microRNA maturation by Drosha. Mol. Cell 2010, 39:373-384. 10.1016/j.molcel.2010.07.011.
-
(2010)
Mol. Cell
, vol.39
, pp. 373-384
-
-
Davis, B.N.1
Hilyard, A.C.2
Nguyen, P.H.3
Lagna, G.4
Hata, A.5
-
25
-
-
79952227351
-
Smad-mediated miRNA processing: a critical role for a conserved RNA sequence
-
Davis-Dusenbery B.N., Hata A. Smad-mediated miRNA processing: a critical role for a conserved RNA sequence. RNA Biol. 2011, 8:71-76. 10.4161/rna.8.1.14299.
-
(2011)
RNA Biol.
, vol.8
, pp. 71-76
-
-
Davis-Dusenbery, B.N.1
Hata, A.2
-
26
-
-
33751252292
-
Direct observation of individual endogenous protein complexes in situ by proximity ligation
-
Söderberg O., Gullberg M., Jarvius M., Ridderstråle K., Leuchowius K.J., Jarvius J., Wester K., Hydbring P., Bahram F., Larsson L.G., Landegren U. Direct observation of individual endogenous protein complexes in situ by proximity ligation. Nat. Methods 2006, 3:995-1000. 10.1038/nmeth947.
-
(2006)
Nat. Methods
, vol.3
, pp. 995-1000
-
-
Söderberg, O.1
Gullberg, M.2
Jarvius, M.3
Ridderstråle, K.4
Leuchowius, K.J.5
Jarvius, J.6
Wester, K.7
Hydbring, P.8
Bahram, F.9
Larsson, L.G.10
Landegren, U.11
-
27
-
-
48049110299
-
Characterizing proteins and their interactions in cells and tissues using the in situ proximity ligation assay
-
Söderberg O., Leuchowius K.J., Gullberg M., Jarvius M., Weibrecht I., Larsson L.G., Landegren U. Characterizing proteins and their interactions in cells and tissues using the in situ proximity ligation assay. Methods 2008, 45:227-232. 10.1016/j.ymeth.2008.06.014.
-
(2008)
Methods
, vol.45
, pp. 227-232
-
-
Söderberg, O.1
Leuchowius, K.J.2
Gullberg, M.3
Jarvius, M.4
Weibrecht, I.5
Larsson, L.G.6
Landegren, U.7
-
28
-
-
84857972182
-
Novel techniques and targets in cardiovascular microRNA research
-
Dangwal S., Bang C., Thum T. Novel techniques and targets in cardiovascular microRNA research. Cardiovasc. Res. 2012, 93:545-554. 10.1093/cvr/cvr297.
-
(2012)
Cardiovasc. Res.
, vol.93
, pp. 545-554
-
-
Dangwal, S.1
Bang, C.2
Thum, T.3
-
30
-
-
84877928475
-
Regulation of miRNA biogenesis as an integrated component of growth factor signaling
-
Blahna M.T., Hata A. Regulation of miRNA biogenesis as an integrated component of growth factor signaling. Curr. Opin. Cell Biol. 2013, 25:233-242. 10.1016/j.ceb.2012.12.005.
-
(2013)
Curr. Opin. Cell Biol.
, vol.25
, pp. 233-242
-
-
Blahna, M.T.1
Hata, A.2
-
31
-
-
84876416274
-
The rough endoplasmatic reticulum is a central nucleation site of siRNA-mediated RNA silencing
-
Stalder L., Heusermann W., Sokol L., Trojer D., Wirz J., Hean J., Fritzsche A., Aeschimann F., Pfanzagl V., Basselet P., Weiler J., Hintersteiner M., Morrissey D.V., Meisner-Kober N.C. The rough endoplasmatic reticulum is a central nucleation site of siRNA-mediated RNA silencing. EMBO J. 2013, 32:1115-1127. 10.1038/emboj.2013.52.
-
(2013)
EMBO J.
, vol.32
, pp. 1115-1127
-
-
Stalder, L.1
Heusermann, W.2
Sokol, L.3
Trojer, D.4
Wirz, J.5
Hean, J.6
Fritzsche, A.7
Aeschimann, F.8
Pfanzagl, V.9
Basselet, P.10
Weiler, J.11
Hintersteiner, M.12
Morrissey, D.V.13
Meisner-Kober, N.C.14
-
32
-
-
78651089753
-
Posttranscriptional gene silencing in nuclei
-
Hoffer P., Ivashuta S., Pontes O., Vitins A., Pikaard C., Mroczka A., Wagner N., Voelker T. Posttranscriptional gene silencing in nuclei. Proc. Natl. Acad. Sci. U. S. A. 2011, 108:409-414. 10.1073/pnas.1009805108.
-
(2011)
Proc. Natl. Acad. Sci. U. S. A.
, vol.108
, pp. 409-414
-
-
Hoffer, P.1
Ivashuta, S.2
Pontes, O.3
Vitins, A.4
Pikaard, C.5
Mroczka, A.6
Wagner, N.7
Voelker, T.8
-
33
-
-
84876244055
-
RNA-induced silencing complex (RISC) proteins PACT, TRBP, and Dicer are SRA binding nuclear receptor coregulators
-
Redfern A.D., Colley S.M., Beveridge D.J., Ikeda N., Epis M.R., Li X., Foulds C.E., Stuart L.M., Barker A., Russell V.J., Ramsay K., Kobelke S.J., Li X., Hatchell E.C., Payne C., Giles K.M., Messineo A., Gatignol A., Lanz R.B., O'Malley B.W., Leedman P.J. RNA-induced silencing complex (RISC) proteins PACT, TRBP, and Dicer are SRA binding nuclear receptor coregulators. Proc. Natl. Acad. Sci. U. S. A. 2013, 110:6536-6541. 10.1073/pnas.1301620110.
-
(2013)
Proc. Natl. Acad. Sci. U. S. A.
, vol.110
, pp. 6536-6541
-
-
Redfern, A.D.1
Colley, S.M.2
Beveridge, D.J.3
Ikeda, N.4
Epis, M.R.5
Li, X.6
Foulds, C.E.7
Stuart, L.M.8
Barker, A.9
Russell, V.J.10
Ramsay, K.11
Kobelke, S.J.12
Li, X.13
Hatchell, E.C.14
Payne, C.15
Giles, K.M.16
Messineo, A.17
Gatignol, A.18
Lanz, R.B.19
O'Malley, B.W.20
Leedman, P.J.21
more..
-
34
-
-
77953032534
-
Emerging paradigms of regulated microRNA processing
-
Newman M.A., Hammond S.M. Emerging paradigms of regulated microRNA processing. Genes Dev. 2010, 24:1086-1092. 10.1101/gad.1919710.
-
(2010)
Genes Dev.
, vol.24
, pp. 1086-1092
-
-
Newman, M.A.1
Hammond, S.M.2
-
35
-
-
77951964981
-
Posttranscriptional regulation of microRNA biogenesis in animals
-
Siomi H., Siomi M.C. Posttranscriptional regulation of microRNA biogenesis in animals. Mol. Cell 2010, 38:323-332. 10.1016/j.molcel.2010.03.013.
-
(2010)
Mol. Cell
, vol.38
, pp. 323-332
-
-
Siomi, H.1
Siomi, M.C.2
-
36
-
-
77955902024
-
The widespread regulation of microRNA biogenesis, function and decay
-
Krol J., Loedige I., Filipowicz W. The widespread regulation of microRNA biogenesis, function and decay. Nat. Rev. Genet. 2010, 11:597-610. 10.1038/nrg2843.
-
(2010)
Nat. Rev. Genet.
, vol.11
, pp. 597-610
-
-
Krol, J.1
Loedige, I.2
Filipowicz, W.3
-
37
-
-
84857772495
-
TDP-43 promotes microRNA biogenesis as a component of the Drosha and Dicer complexes
-
Kawahara Y., Mieda-Sato A. TDP-43 promotes microRNA biogenesis as a component of the Drosha and Dicer complexes. Proc. Natl. Acad. Sci. U. S. A. 2012, 109:3347-3352. 10.1073/pnas.1112427109.
-
(2012)
Proc. Natl. Acad. Sci. U. S. A.
, vol.109
, pp. 3347-3352
-
-
Kawahara, Y.1
Mieda-Sato, A.2
-
38
-
-
84880720020
-
Deficiency of Smad7 enhances cardiac remodeling induced by angiotensin II infusion in a mouse model of hypertension
-
Wei L.H., Huang X.R., Zhang Y., Li Y.Q., Chen H.Y., Heuchel R., Yan B.P., Yu C.M., Lan H.Y. Deficiency of Smad7 enhances cardiac remodeling induced by angiotensin II infusion in a mouse model of hypertension. PLoS One 2013, 8:e70195. 10.1371/journal.pone.0070195.
-
(2013)
PLoS One
, vol.8
, pp. e70195
-
-
Wei, L.H.1
Huang, X.R.2
Zhang, Y.3
Li, Y.Q.4
Chen, H.Y.5
Heuchel, R.6
Yan, B.P.7
Yu, C.M.8
Lan, H.Y.9
-
39
-
-
24044458235
-
Combination of tumor necrosis factor-alpha ablation and matrix metalloproteinase inhibition prevents heart failure after pressure overload in tissue inhibitor of metalloproteinase-3 knock-out mice
-
Kassiri Z., Oudit G.Y., Sanchez O., Dawood F., Mohammed F.F., Nuttall R.K., Edwards D.R., Liu P.P., Backx P.H., Khokha R. Combination of tumor necrosis factor-alpha ablation and matrix metalloproteinase inhibition prevents heart failure after pressure overload in tissue inhibitor of metalloproteinase-3 knock-out mice. Circ. Res. 2005, 19:380-390. 10.1161/01.RES.0000178789.16929.cf.
-
(2005)
Circ. Res.
, vol.19
, pp. 380-390
-
-
Kassiri, Z.1
Oudit, G.Y.2
Sanchez, O.3
Dawood, F.4
Mohammed, F.F.5
Nuttall, R.K.6
Edwards, D.R.7
Liu, P.P.8
Backx, P.H.9
Khokha, R.10
|