FTY720 reduces migration and invasion of human glioblastoma cell lines via inhibiting the PI3K/AKT/mTOR/p70S6K signaling pathway

Tumor Biology

Volumn 35, Issue 11, 2014, Pages 10707-10714

  Zhang, Li ^a   Wang, Handong ^a   Zhu, Jianhong ^a   Ding, Ke ^a   Xu, Jianguo ^a  

^a NANJING UNIVERSITY   (China)

Author keywords

FTY720; Glioblastoma; Invasion; Migration; PI3K AKT mTOR p70S6K

Indexed keywords

FINGOLIMOD; IMMUNOSUPPRESSIVE AGENT; MTOR PROTEIN, HUMAN; PHOSPHATIDYLINOSITOL 3 KINASE; PROPANEDIOL DERIVATIVE; PROTEIN KINASE B; S6 KINASE; SPHINGOSINE; TARGET OF RAPAMYCIN KINASE;

ANALOGS AND DERIVATIVES; ANTAGONISTS AND INHIBITORS; APOPTOSIS; CELL MOTION; CELL PROLIFERATION; DRUG EFFECTS; GLIOBLASTOMA; HUMAN; METABOLISM; PATHOLOGY; SIGNAL TRANSDUCTION; TUMOR CELL CULTURE; TUMOR INVASION; WESTERN BLOTTING; WOUND HEALING;

APOPTOSIS; BLOTTING, WESTERN; CELL MOVEMENT; CELL PROLIFERATION; GLIOBLASTOMA; HUMANS; IMMUNOSUPPRESSIVE AGENTS; NEOPLASM INVASIVENESS; PHOSPHATIDYLINOSITOL 3-KINASES; PROPYLENE GLYCOLS; PROTO-ONCOGENE PROTEINS C-AKT; RIBOSOMAL PROTEIN S6 KINASES, 70-KDA; SIGNAL TRANSDUCTION; SPHINGOSINE; TOR SERINE-THREONINE KINASES; TUMOR CELLS, CULTURED; WOUND HEALING;

EID: 84928589926     PISSN: 10104283     EISSN: None     Source Type: Journal    
DOI: 10.1007/s13277-014-2386-y     Document Type: Article

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