Tristetraprolin recruits the herpes simplex virion host shutoff RNase to AU-rich elements in stress response mrnas to enable their cleavage

Journal of Virology

Volumn 89, Issue 10, 2015, Pages 5643-5650

  Shu, Minfeng ^a   Taddeo, Brunella ^a   Roizman, Bernard ^a  

^a UNIVERSITY OF CHICAGO   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

RIBONUCLEASE; TRISTETRAPROLIN; UNCLASSIFIED DRUG; VIRION HOST SHUTOFF RIBONUCLEASE; 3' UNTRANSLATED REGION; APOPTOSIS REGULATORY PROTEIN; HYBRID PROTEIN; IER3 PROTEIN, HUMAN; MEMBRANE PROTEIN; MESSENGER RNA; VIRION HOST SHUTOFF PROTEIN, SIMPLEXVIRUS; VIRUS PROTEIN; ZFP36 PROTEIN, HUMAN;

3' UNTRANSLATED REGION; AMINO ACID SUBSTITUTION; ARTICLE; BINDING AFFINITY; BINDING SITE; CELLULAR STRESS RESPONSE; CONTROLLED STUDY; GENE MAPPING; HERPES SIMPLEX VIRUS; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN PROTEIN INTERACTION; PROTEIN RNA BINDING; RNA CLEAVAGE; WILD TYPE; AMINO ACID SEQUENCE; AU RICH ELEMENT; CHEMISTRY; GENETICS; HEK293 CELL LINE; HERPES SIMPLEX VIRUS 1; HOST PATHOGEN INTERACTION; HUMAN; METABOLISM; MOLECULAR GENETICS; NUCLEOTIDE SEQUENCE; SITE DIRECTED MUTAGENESIS; VIRION;

SIMPLEXVIRUS;

3' UNTRANSLATED REGIONS; AMINO ACID SEQUENCE; AMINO ACID SUBSTITUTION; APOPTOSIS REGULATORY PROTEINS; AU RICH ELEMENTS; BASE SEQUENCE; HEK293 CELLS; HERPESVIRUS 1, HUMAN; HOST-PATHOGEN INTERACTIONS; HUMANS; MEMBRANE PROTEINS; MOLECULAR SEQUENCE DATA; MUTAGENESIS, SITE-DIRECTED; PROTEIN INTERACTION DOMAINS AND MOTIFS; RECOMBINANT FUSION PROTEINS; RIBONUCLEASES; RNA, MESSENGER; TRISTETRAPROLIN; VIRAL PROTEINS; VIRION;

EID: 84928576496     PISSN: 0022538X     EISSN: 10985514     Source Type: Journal    
DOI: 10.1128/JVI.00091-15     Document Type: Article

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