The virion-packaged endoribonuclease of herpes simplex virus 1 cleaves mRNA in polyribosomes

Proceedings of the National Academy of Sciences of the United States of America

Volumn 106, Issue 29, 2009, Pages 12139-12144

  Taddeo, Brunella ^a   Zhang, Weiran ^a   Roizman, Bernard ^a  

^a UNIVERSITY OF CHICAGO   (United States)

Author keywords

AU rich elements RNA; RNase

Indexed keywords

GLYCERALDEHYDE 3 PHOSPHATE DEHYDROGENASE; MESSENGER RNA; POLYADENYLIC ACID; RIBONUCLEASE;

3' UNTRANSLATED REGION; 5' UNTRANSLATED REGION; ARTICLE; CONTROLLED STUDY; CYTOPLASM; HERPES SIMPLEX VIRUS 1; HOUSEKEEPING GENE; HUMAN; HUMAN CELL; NONHUMAN; POLYSOME; PRIORITY JOURNAL; PROTEIN DOMAIN; RNA CLEAVAGE; RNA DEGRADATION; RNA TRANSLATION; SUCROSE GRADIENT; VIRION; VIRUS GENE; WILD TYPE;

APOPTOSIS REGULATORY PROTEINS; CYCLOHEXIMIDE; CYTOPLASMIC STRUCTURES; ENDORIBONUCLEASES; HELA CELLS; HERPES SIMPLEX; HERPESVIRUS 1, HUMAN; HUMANS; MEMBRANE PROTEINS; MODELS, BIOLOGICAL; POLYRIBOSOMES; RNA, MESSENGER; TIME FACTORS; VIRAL PROTEINS; VIRION; VIRUS ASSEMBLY;

HUMAN HERPESVIRUS 1;

EID: 67749088599     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.0905828106     Document Type: Article

References (30)

1. Taddeo B, Zhang W, Roizman B (2006) The UL41 protein of herpes simplex virus 1 degrades RNA by endonucleolytic cleavage in absence of other cellular or viral proteins. Proc Natl Acad Sci USA 103:2827-2832.
2. L41 of herpes simplex virus 1 is an endoribonuclease with a substrate specificity similar to that of RNase A. J Virol 80:9341-9345.
3. Smiley JR (2004) Herpes simplex virus virion host shutoff protein: Immune evasion mediated by a viral RNase? J Virol 78:1063-1068.
4. L41 gene-dependent destabilization of cellular RNAs is selective and may be sequence-specific. Proc Natl Acad Sci USA 101:3603-3608.
5. Esclatine A, Taddeo B, Roizman B (2004) The UL41 protein of herpes simplex virus mediates selective stabilization or degradation of cellular mRNAs. Proc Natl Acad Sci USA 101:18165-18170.
6. Garneau NL, Wilusz J, Wilusz CJ (2007) The highways and byways of mRNA decay. Nat Rev Mol Cell Biol 8:113-126.
7. Parker R, Song H (2004) The enzymes and control of eukaryotic mRNA turnover. Nat Struct Mol Biol 11:121-127.
8. Wilusz CJ, Wilusz J (2004) Bringing the role of mRNA decay in the control of gene expression into focus. Trends Genet 20:491-497.
9. Houseley J, LaCava J, Tollervey D (2006) RNA-quality control by the exosome. Nat Rev Mol Cell Biol 7:529-539.
10. Wilusz CJ, Wormington M, Peltz SW (2001) The cap-to-tail guide to mRNA turnover. Nat Rev Mol Cell Biol 2:237-246.
11. Dompenciel RE, Garnepudi VR, Schoenberg DR (1995) Purification and characterization of an estrogen-regulated Xenopus liver polysomal nuclease involved in selective destabilization of albumin mRNA. J Biol Chem 278:6108-6118.
12. Yang F, Schoenberg DR (2004) Endonuclease-mediated mRNA decay involves the selective targeting of PMR1 to polyribosome-bound substrate mRNA. Mol Cell 14:435-445.
13. Peng Y, Schoenberg DR (2007) c-Src activates endonuclease-mediated mRNA decay. Mol Cell 25:779-787.
14. Sheth U, Parker R (2003) Decapping and decay of messenger RNA occur in cytoplasmic processing bodies. Science 300:805-808.
15. Teixeira D, Sheth U, Vlencia-Sanchez MA, Brengues M, Parker R (2005) Processing bodies require RNA for assembly and contain nontranslating mRNAs. RNA 11:371-382.
16. Cougot N, Babajko S, Seraphin B (2004) Cytoplasmic foci are sites of mRNA decay in human cells. J Cell Biol 165:31-40.
17. Sydiskis RJ, Roizman B (1966) Polysomes and protein synthesis in cells infected with a DNA virus. Science 153:76-78.
18. Sydiskis RJ, Roizman B (1967) The disaggregation of host polyribosomes in productive and abortive infection with herpes simplex virus. Virology 32:678-686.
19. Fenwick L, Walker MJ (1978) Suppression of the synthesis of cellular macromolecules by herpes simplex virus. J Gen Virol 41:37-51.
20. Strom T, Frenkel N (1978) Effects of herpes simplex virus on mRNA stability. J Virol 61:2198-2207.
21. Kedersha N, Anderson P (2007) Mammalian stress granules and processing bodies. Methods Enzymol 431:61-81.
22. Everly DN, Jr, Feng P, Mian IS, Read GS (2002) mRNA degradation by the virion host shutoff (Vhs) protein of herpes simplex virus: Genetic and biochemical evidence that Vhs is a nuclease. J Virol 76:8560-8571.
23. Feng P, Everly DN, Jr, Read GS (2001) mRNA decay during herpesvirus infections: Interaction between a putative viral nuclease and a cellular translation factor. J Virol 75:10272-10280.
24. Feng P, Everly DN, Jr, Read GS (2005) mRNA decay during herpes simplex virus (HSV) infections: Protein-protein interactions involving the HSV virion host shutoff protein and translation factors eIF4H and eIF4A. J Virol 79:9651-9664.
25. Sarma N, Agarwal D, Shiflett LA, Read GS (2008) Small interfering RNAs that deplete the cellular translation factor eIF4H impede mRNA degradation by the virion host shutoff protein of herpes simplex virus. J Virol 82:6600-6609.
26. Sonenberg N, Hinnebusch AG (2009) Regulation of translation initiation in Eukaryotes: Mechanisms and biological targets. Cell 136:731-745.
27. Esclatine A, Taddeo B, Roizman B (2004) Herpes simplex virus 1 induces cytoplasmic accumulation of TIA-1/TIAR and both synthesis and cytoplasmic accumulation of tristetraprolin, two cellular proteins that bind and destabilize AU-rich RNAs. J Virol 78:8582-8592.
28. Poon AP, Roizman B (1997) Differentiation of the shutoff of protein synthesis by virion host shutoff and mutant γ134.5 genes of herpes simplex virus 1. Virology 229:98-105.
29. Fenger-Gron M, Fillman C, Norrild B, Lykke-Andersen J (2005) Multiple processing body factors and the ARE binding protein TTP activate mRNA decapping. Mol Cell 20:905-915.
30. Taddeo B, Esclatine A, Zhang W, Roizman B (2003) The stress-inducible immediateearly responsive gene IEX-1 is activated in cells infected with herpes simplex virus 1, but several viral mechanisms, including 3′ degradation of its RNA, preclude expression of the gene. J Virol 77:6178-6187.