메뉴 건너뛰기




Volumn 89, Issue 10, 2015, Pages 5502-5514

Increased levels of macrophage inflammatory proteins result in resistance to R5-tropic HIV-1 in a subset of elite controllers

Author keywords

[No Author keywords available]

Indexed keywords

MACROPHAGE INFLAMMATORY PROTEIN 1ALPHA; MACROPHAGE INFLAMMATORY PROTEIN 1BETA; RANTES; BETA CHEMOKINE; CCL3 PROTEIN, HUMAN; CCL3L1 PROTEIN, HUMAN; CCL4 PROTEIN, HUMAN; CCL5 PROTEIN, HUMAN; CCR5 PROTEIN, HUMAN; CHEMOKINE RECEPTOR CCR5; CHEMOKINE RECEPTOR CXCR4; CXCR4 PROTEIN, HUMAN; MACROPHAGE INFLAMMATORY PROTEIN; MESSENGER RNA;

EID: 84928573402     PISSN: 0022538X     EISSN: 10985514     Source Type: Journal    
DOI: 10.1128/JVI.00118-15     Document Type: Article
Times cited : (30)

References (61)
  • 1
    • 34548689151 scopus 로고    scopus 로고
    • Human immunodeficiency virus controllers: mechanisms of durable virus control in the absence of antiretroviral therapy
    • Deeks SG, Walker BD. 2007. Human immunodeficiency virus controllers: mechanisms of durable virus control in the absence of antiretroviral therapy. Immunity 27:406-416. http://dx.doi.org/10.1016/j.immuni.2007.08.010.
    • (2007) Immunity , vol.27 , pp. 406-416
    • Deeks, S.G.1    Walker, B.D.2
  • 3
    • 70349762846 scopus 로고    scopus 로고
    • Natural viral suppressors of HIV-1 have a unique capacity to maintain gammadelta T cells
    • Riedel DJ, Sajadi MM, Armstrong CL, Cummings JS, Cairo C, Redfield RR, Pauza CD. 2009. Natural viral suppressors of HIV-1 have a unique capacity to maintain gammadelta T cells. AIDS 23:1955-1964. http://dx.doi.org/10.1097/QAD.0b013e32832ff1ff.
    • (2009) AIDS , vol.23 , pp. 1955-1964
    • Riedel, D.J.1    Sajadi, M.M.2    Armstrong, C.L.3    Cummings, J.S.4    Cairo, C.5    Redfield, R.R.6    Pauza, C.D.7
  • 7
    • 0027172407 scopus 로고
    • The characterization of non-progressors: long-term HIV-1 infection with stable CD4+T-cell levels
    • Sheppard HW, Lang W, Ascher MS, Vittinghoff E, Winkelstein W. 1993. The characterization of non-progressors: long-term HIV-1 infection with stable CD4+T-cell levels. AIDS 7:1159-1166. http://dx.doi.org/10.1097/00002030-199309000-00002.
    • (1993) AIDS , vol.7 , pp. 1159-1166
    • Sheppard, H.W.1    Lang, W.2    Ascher, M.S.3    Vittinghoff, E.4    Winkelstein, W.5
  • 11
    • 73549099347 scopus 로고    scopus 로고
    • Effector mechanisms in HIV-1 infected elite controllers: highly active immune responses?
    • Blankson JN. 2010. Effector mechanisms in HIV-1 infected elite controllers: highly active immune responses? Antiviral Res 85:295-302. http://dx.doi.org/10.1016/j.antiviral.2009.08.007.
    • (2010) Antiviral Res , vol.85 , pp. 295-302
    • Blankson, J.N.1
  • 12
    • 70449657764 scopus 로고    scopus 로고
    • Elucidating the elite: mechanisms of control in HIV-1 infection
    • O'Connell KA, Bailey JR, Blankson JN. 2009. Elucidating the elite: mechanisms of control in HIV-1 infection. Trends Pharmacol Sci 30:631-637. http://dx.doi.org/10.1016/j.tips.2009.09.005.
    • (2009) Trends Pharmacol Sci , vol.30 , pp. 631-637
    • O'Connell, K.A.1    Bailey, J.R.2    Blankson, J.N.3
  • 13
    • 27644489746 scopus 로고    scopus 로고
    • Phenotypic, functional, and kinetic parameters associated with apparent T-cell control of human immunodeficiency virus replication in individuals with and without antiretroviral treatment
    • Emu B, Sinclair E, Favre D, Moretto WJ, Hsue P, Hoh R, Martin JN, Nixon DF, McCune JM, Deeks SG. 2005. Phenotypic, functional, and kinetic parameters associated with apparent T-cell control of human immunodeficiency virus replication in individuals with and without antiretroviral treatment. J Virol 79:14169-14178. http://dx.doi.org/10.1128/JVI.79.22.14169-14178.2005.
    • (2005) J Virol , vol.79 , pp. 14169-14178
    • Emu, B.1    Sinclair, E.2    Favre, D.3    Moretto, W.J.4    Hsue, P.5    Hoh, R.6    Martin, J.N.7    Nixon, D.F.8    McCune, J.M.9    Deeks, S.G.10
  • 14
    • 43949124825 scopus 로고    scopus 로고
    • HLA class I-restricted T-cell responses may contribute to the control of human immunodeficiency virus infection, but such responses are not always necessary for long-term virus control
    • Emu B, Sinclair E, Hatano H, Ferre A, Shacklett B, Martin JN, McCune JM, Deeks SG. 2008. HLA class I-restricted T-cell responses may contribute to the control of human immunodeficiency virus infection, but such responses are not always necessary for long-term virus control. J Virol 82:5398-5407. http://dx.doi.org/10.1128/JVI.02176-07.
    • (2008) J Virol , vol.82 , pp. 5398-5407
    • Emu, B.1    Sinclair, E.2    Hatano, H.3    Ferre, A.4    Shacklett, B.5    Martin, J.N.6    McCune, J.M.7    Deeks, S.G.8
  • 18
    • 79952072932 scopus 로고    scopus 로고
    • Elite suppressors harbor low levels of integrated HIV DNA and high levels of 2-LTR circular HIV DNA compared to HIV+ patients on and off HAART
    • Graf EH, Mexas AM, Yu JJ, Shaheen F, Liszewski MK, Di Mascio M, Migueles SA, Connors M, O'Doherty U. 2011. Elite suppressors harbor low levels of integrated HIV DNA and high levels of 2-LTR circular HIV DNA compared to HIV+ patients on and off HAART. PLoS Pathog 7:e1001300. http://dx.doi.org/10.1371/journal.ppat.1001300.
    • (2011) PLoS Pathog , vol.7
    • Graf, E.H.1    Mexas, A.M.2    Yu, J.J.3    Shaheen, F.4    Liszewski, M.K.5    Di Mascio, M.6    Migueles, S.A.7    Connors, M.8    O'Doherty, U.9
  • 21
    • 18844454267 scopus 로고    scopus 로고
    • HIV-1-specific IFN-gamma/IL-2-secreting CD8 T cells support CD4-independent proliferation of HIV-1-specific CD8 T cells
    • Zimmerli SC, Harari A, Cellerai C, Vallelian F, Bart PA, Pantaleo G. 2005. HIV-1-specific IFN-gamma/IL-2-secreting CD8 T cells support CD4-independent proliferation of HIV-1-specific CD8 T cells. Proc Natl Acad Sci USA 102:7239-7244. http://dx.doi.org/10.1073/pnas.0502393102.
    • (2005) Proc Natl Acad Sci USA , vol.102 , pp. 7239-7244
    • Zimmerli, S.C.1    Harari, A.2    Cellerai, C.3    Vallelian, F.4    Bart, P.A.5    Pantaleo, G.6
  • 25
    • 33646453478 scopus 로고    scopus 로고
    • Neutralizing antibodies do not mediate suppression of human immunodeficiency virus type 1 in elite suppressors or selection of plasma virus variants in patients on highly active antiretroviral therapy
    • Bailey JR, Lassen KG, Yang HC, Quinn TC, Ray SC, Blankson JN, Siliciano RF. 2006. Neutralizing antibodies do not mediate suppression of human immunodeficiency virus type 1 in elite suppressors or selection of plasma virus variants in patients on highly active antiretroviral therapy. J Virol 80: 4758-4770. http://dx.doi.org/10.1128/JVI.80.10.4758-4770.2006.
    • (2006) J Virol , vol.80 , pp. 4758-4770
    • Bailey, J.R.1    Lassen, K.G.2    Yang, H.C.3    Quinn, T.C.4    Ray, S.C.5    Blankson, J.N.6    Siliciano, R.F.7
  • 26
    • 40149092360 scopus 로고    scopus 로고
    • Role of APOBEC3G/F-mediated hypermutation in the control of human immunodeficiency virus type 1 in elite suppressors
    • Gandhi SK, Siliciano JD, Bailey JR, Siliciano RF, Blankson JN. 2008. Role of APOBEC3G/F-mediated hypermutation in the control of human immunodeficiency virus type 1 in elite suppressors. J Virol 82:3125-3130. http://dx.doi.org/10.1128/JVI.01533-07.
    • (2008) J Virol , vol.82 , pp. 3125-3130
    • Gandhi, S.K.1    Siliciano, J.D.2    Bailey, J.R.3    Siliciano, R.F.4    Blankson, J.N.5
  • 27
    • 65349168831 scopus 로고    scopus 로고
    • Role of natural killer cells in a cohort of elite suppressors: low frequency of the protective KIR3DS1 allele and limited inhibition of human immunodeficiency virus type 1 replication in vitro
    • O'Connell KA, Han Y, Williams TM, Siliciano RF, Blankson JN. 2009. Role of natural killer cells in a cohort of elite suppressors: low frequency of the protective KIR3DS1 allele and limited inhibition of human immunodeficiency virus type 1 replication in vitro. J Virol 83:5028-5034. http://dx.doi.org/10.1128/JVI.02551-08.
    • (2009) J Virol , vol.83 , pp. 5028-5034
    • O'Connell, K.A.1    Han, Y.2    Williams, T.M.3    Siliciano, R.F.4    Blankson, J.N.5
  • 28
    • 77956672262 scopus 로고    scopus 로고
    • Ex vivo T cell-based HIV suppression assay to evaluate HIV-specific CD8+ T-cell responses
    • Saez-Cirion A, Shin SY, Versmisse P, Barre-Sinoussi F, Pancino G. 2010. Ex vivo T cell-based HIV suppression assay to evaluate HIV-specific CD8+ T-cell responses. Nat Protoc 5:1033-1041. http://dx.doi.org/10.1038/nprot.2010.73.
    • (2010) Nat Protoc , vol.5 , pp. 1033-1041
    • Saez-Cirion, A.1    Shin, S.Y.2    Versmisse, P.3    Barre-Sinoussi, F.4    Pancino, G.5
  • 32
    • 78650657805 scopus 로고    scopus 로고
    • Unstimulated primary CD4+ T cells from HIV-1-positive elite suppressors are fully susceptible to HIV-1 entry and productive infection
    • Rabi SA, O'Connell KA, Nikolaeva D, Bailey JR, Jilek BL, Shen L, Page KR, Siliciano RF, Blankson JN. 2011. Unstimulated primary CD4+ T cells from HIV-1-positive elite suppressors are fully susceptible to HIV-1 entry and productive infection. J Virol 85:979-986. http://dx.doi.org/10.1128/JVI.01721-10.
    • (2011) J Virol , vol.85 , pp. 979-986
    • Rabi, S.A.1    O'Connell, K.A.2    Nikolaeva, D.3    Bailey, J.R.4    Jilek, B.L.5    Shen, L.6    Page, K.R.7    Siliciano, R.F.8    Blankson, J.N.9
  • 33
    • 80053085028 scopus 로고    scopus 로고
    • CD4+ T cells from elite suppressors are more susceptible to HIV-1 but produce fewer virions than cells from chronic progressors
    • O'Connell KA, Rabi SA, Siliciano RF, Blankson JN. 2011. CD4+ T cells from elite suppressors are more susceptible to HIV-1 but produce fewer virions than cells from chronic progressors. Proc Natl Acad Sci U S A 108:E689-E698. http://dx.doi.org/10.1073/pnas.1108866108.
    • (2011) Proc Natl Acad Sci U S A , vol.108 , pp. E689-E698
    • O'Connell, K.A.1    Rabi, S.A.2    Siliciano, R.F.3    Blankson, J.N.4
  • 34
  • 35
    • 84876926824 scopus 로고    scopus 로고
    • LDL receptor and its family members serve as the cellular receptors for vesicular stomatitis virus
    • Finkelshtein D, Werman A, Novick D, Barak S, Rubinstein M. 2013. LDL receptor and its family members serve as the cellular receptors for vesicular stomatitis virus. Proc Natl Acad Sci U S A 110:7306-7311. http://dx.doi.org/10.1073/pnas.1214441110.
    • (2013) Proc Natl Acad Sci U S A , vol.110 , pp. 7306-7311
    • Finkelshtein, D.1    Werman, A.2    Novick, D.3    Barak, S.4    Rubinstein, M.5
  • 38
    • 84876996918 scopus 로고    scopus 로고
    • TopHat2: accurate alignment of transcriptomes in the presence of insertions, deletions and gene fusions
    • Kim D, Pertea G, Trapnell C, Pimentel H, Kelley R, Salzberg SL. 2013. TopHat2: accurate alignment of transcriptomes in the presence of insertions, deletions and gene fusions. Genome Biol 14:R36. http://dx.doi.org/10.1186/gb-2013-14-4-r36.
    • (2013) Genome Biol , vol.14 , pp. R36
    • Kim, D.1    Pertea, G.2    Trapnell, C.3    Pimentel, H.4    Kelley, R.5    Salzberg, S.L.6
  • 39
    • 79957842166 scopus 로고    scopus 로고
    • Computational methods for transcriptome annotation and quantification using RNA-seq
    • Garber M, Grabherr MG, Guttman M, Trapnell C. 2011. Computational methods for transcriptome annotation and quantification using RNA-seq. Nat Methods 8:469-477. http://dx.doi.org/10.1038/nmeth.1613.
    • (2011) Nat Methods , vol.8 , pp. 469-477
    • Garber, M.1    Grabherr, M.G.2    Guttman, M.3    Trapnell, C.4
  • 41
    • 0035145202 scopus 로고    scopus 로고
    • Spectrofluorimetric analysis of CCR5-delta 32 allele using real-time polymerase chain reaction: prevalence in southern Spanish HIV(+) patients and noninfected population
    • Ruiz A, Royo JL, Rubio A, Borrego S, Leal M, Sanchez B, Nunez-Roldan A, Antinolo G. 2001. Spectrofluorimetric analysis of CCR5-delta 32 allele using real-time polymerase chain reaction: prevalence in southern Spanish HIV(+) patients and noninfected population. AIDS Res Hum Retroviruses 17:191-193. http://dx.doi.org/10.1089/08892220150217283.
    • (2001) AIDS Res Hum Retroviruses , vol.17 , pp. 191-193
    • Ruiz, A.1    Royo, J.L.2    Rubio, A.3    Borrego, S.4    Leal, M.5    Sanchez, B.6    Nunez-Roldan, A.7    Antinolo, G.8
  • 42
    • 44449140104 scopus 로고    scopus 로고
    • IL-27 activates human monocytes via STAT1 and suppresses IL-10 production but the inflammatory functions of IL-27 are abrogated by TLRs and p38
    • Kalliolias GD, Ivashkiv LB. 2008. IL-27 activates human monocytes via STAT1 and suppresses IL-10 production but the inflammatory functions of IL-27 are abrogated by TLRs and p38. J Immunol 180:6325-6333. http://dx.doi.org/10.4049/jimmunol.180.9.6325.
    • (2008) J Immunol , vol.180 , pp. 6325-6333
    • Kalliolias, G.D.1    Ivashkiv, L.B.2
  • 43
    • 79957898600 scopus 로고    scopus 로고
    • C/EBP-alpha and C/EBP-beta-mediated adipogenesis of human mesenchymal stem cells (hMSCs) using PLGA nanoparticles complexed with poly(ethyleneimmine)
    • Yang HN, Park JS, Woo DG, Jeon SY, Do HJ, Lim HY, Kim JH, Park KH. 2011. C/EBP-alpha and C/EBP-beta-mediated adipogenesis of human mesenchymal stem cells (hMSCs) using PLGA nanoparticles complexed with poly(ethyleneimmine). Biomaterials 32:5924-5933. http://dx.doi.org/10.1016/j.biomaterials.2011.04.072.
    • (2011) Biomaterials , vol.32 , pp. 5924-5933
    • Yang, H.N.1    Park, J.S.2    Woo, D.G.3    Jeon, S.Y.4    Do, H.J.5    Lim, H.Y.6    Kim, J.H.7    Park, K.H.8
  • 44
    • 33747642956 scopus 로고    scopus 로고
    • Cigarette smoke extract enhances oxytocin-induced rhythmic contractions of rat and human preterm myometrium
    • Nakamoto T, Yasuda K, Yasuhara M, Nakajima T, Mizokami T, Okada H, Kanzaki H. 2006. Cigarette smoke extract enhances oxytocin-induced rhythmic contractions of rat and human preterm myometrium. Reproduction 132:343-353. http://dx.doi.org/10.1530/rep.1.00908.
    • (2006) Reproduction , vol.132 , pp. 343-353
    • Nakamoto, T.1    Yasuda, K.2    Yasuhara, M.3    Nakajima, T.4    Mizokami, T.5    Okada, H.6    Kanzaki, H.7
  • 46
    • 0036772531 scopus 로고    scopus 로고
    • Gene copy number regulates the production of the human chemokine CCL3-L1
    • Townson JR, Barcellos LF, Nibbs RJ. 2002. Gene copy number regulates the production of the human chemokine CCL3-L1. Eur J Immunol 32: 3016-3026. http://dx.doi.org/10.1002/1521-4141(2002010)32:10<3016::AID-IMMU3016>3.0.CO;2-D.
    • (2002) Eur J Immunol , vol.32 , pp. 3016-3026
    • Townson, J.R.1    Barcellos, L.F.2    Nibbs, R.J.3
  • 47
    • 77956545747 scopus 로고    scopus 로고
    • Copy number variation in chemokine superfamily: the complex scene of CCL3L-CCL4L genes in health and disease
    • Colobran R, Pedrosa E, Carretero-Iglesia L, Juan M. 2010. Copy number variation in chemokine superfamily: the complex scene of CCL3L-CCL4L genes in health and disease. Clin Exp Immunol 162:41-52. http://dx.doi.org/10.1111/j.1365-2249.2010.04224.x.
    • (2010) Clin Exp Immunol , vol.162 , pp. 41-52
    • Colobran, R.1    Pedrosa, E.2    Carretero-Iglesia, L.3    Juan, M.4
  • 49
    • 0029417004 scopus 로고
    • Identification of RANTES, MIP-1 alpha, and MIP-1 beta as the major HIV-suppressive factors produced by CD8+ T cells
    • Cocchi F, DeVico AL, Garzino-Demo A, Arya SK, Gallo RC, Lusso P. 1995. Identification of RANTES, MIP-1 alpha, and MIP-1 beta as the major HIV-suppressive factors produced by CD8+ T cells. Science 270: 1811-1815. http://dx.doi.org/10.1126/science.270.5243.1811.
    • (1995) Science , vol.270 , pp. 1811-1815
    • Cocchi, F.1    DeVico, A.L.2    Garzino-Demo, A.3    Arya, S.K.4    Gallo, R.C.5    Lusso, P.6
  • 50
    • 0031964686 scopus 로고    scopus 로고
    • Endogenous production of beta-chemokines by CD4+, but not CD8+, T-cell clones correlates with the clinical state of human immunodeficiency virus type 1 (HIV-1)-infected individuals and may be responsible for blocking infection with non-syncytium-inducing HIV-1 in vitro
    • Saha K, Bentsman G, Chess L, Volsky DJ. 1998. Endogenous production of beta-chemokines by CD4+, but not CD8+, T-cell clones correlates with the clinical state of human immunodeficiency virus type 1 (HIV-1)-infected individuals and may be responsible for blocking infection with non-syncytium-inducing HIV-1 in vitro. J Virol 72:876-881.
    • (1998) J Virol , vol.72 , pp. 876-881
    • Saha, K.1    Bentsman, G.2    Chess, L.3    Volsky, D.J.4
  • 52
    • 0033543083 scopus 로고    scopus 로고
    • Sustained suppression of plasma HIV RNA is associated with an increase in the production of mitogen-induced MIP-1alpha and MIP-1beta
    • Kumar D, Parato K, Kumar A, Sun E, Cameron DW, Angel JB. 1999. Sustained suppression of plasma HIV RNA is associated with an increase in the production of mitogen-induced MIP-1alpha and MIP-1beta. AIDS Res Hum Retroviruses 15:1073-1077. http://dx.doi.org/10.1089/088922299310368.
    • (1999) AIDS Res Hum Retroviruses , vol.15 , pp. 1073-1077
    • Kumar, D.1    Parato, K.2    Kumar, A.3    Sun, E.4    Cameron, D.W.5    Angel, J.B.6
  • 53
    • 0036889118 scopus 로고    scopus 로고
    • Macrophage inflammatory protein-1
    • Menten P, Wuyts A, Van Damme J. 2002. Macrophage inflammatory protein-1. Cytokine Growth Factor Rev 13:455-481. http://dx.doi.org/10.1016/S1359-6101(02)00045-X.
    • (2002) Cytokine Growth Factor Rev , vol.13 , pp. 455-481
    • Menten, P.1    Wuyts, A.2    Van Damme, J.3
  • 54
    • 0034744508 scopus 로고    scopus 로고
    • The LD78beta isoform of MIP-1alpha is the most potent CC-chemokine in inhibiting CCR5-dependent human immunodeficiency virus type 1 replication in human macrophages
    • Aquaro S, Menten P, Struyf S, Proost P, Van Damme J, De Clercq E, Schols D. 2001. The LD78beta isoform of MIP-1alpha is the most potent CC-chemokine in inhibiting CCR5-dependent human immunodeficiency virus type 1 replication in human macrophages. J Virol 75:4402-4406. http://dx.doi.org/10.1128/JVI.75.9.4402-4406.2001.
    • (2001) J Virol , vol.75 , pp. 4402-4406
    • Aquaro, S.1    Menten, P.2    Struyf, S.3    Proost, P.4    Van Damme, J.5    De Clercq, E.6    Schols, D.7
  • 55
    • 84910133583 scopus 로고    scopus 로고
    • Human gene copy number variation and infectious disease
    • Hollox EJ, Hoh BP. 2014. Human gene copy number variation and infectious disease. Hum Genet 133:1217-1233. http://dx.doi.org/10.1007/s00439-014-1457-x.
    • (2014) Hum Genet , vol.133 , pp. 1217-1233
    • Hollox, E.J.1    Hoh, B.P.2
  • 59
    • 34247608805 scopus 로고    scopus 로고
    • CCL3L1 and CCL4L1: variable gene copy number in adolescents with and without human immunodeficiency virus type 1 (HIV-1) infection
    • Shao W, Tang J, Song W, Wang C, Li Y, Wilson CM, Kaslow RA. 2007. CCL3L1 and CCL4L1: variable gene copy number in adolescents with and without human immunodeficiency virus type 1 (HIV-1) infection. Genes Immun 8:224-231. http://dx.doi.org/10.1038/sj.gene.6364378.
    • (2007) Genes Immun , vol.8 , pp. 224-231
    • Shao, W.1    Tang, J.2    Song, W.3    Wang, C.4    Li, Y.5    Wilson, C.M.6    Kaslow, R.A.7


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.