메뉴 건너뛰기




Volumn 3, Issue 9, 2008, Pages

CCL3L1-CCR5 genotype improves the assessment of AIDS risk in HIV-1-infected individuals

(12)  Kulkarni, Hemant a,b   Agan, Brian K c,d,e,f   Marconi, Vincent C c,d,f   O'Connell, Robert J c,d   Camargo, Jose F a,b   He, Weijing a,b   Delmar, Judith c,d,f   Phelps, Kenneth R g,h   Crawford, George a   Clark, Robert A a   Dolan, Matthew J c,d,e,f   Ahuja, Sunil K a,b,i  


Author keywords

[No Author keywords available]

Indexed keywords

CHEMOKINE RECEPTOR CCR5; MACROPHAGE INFLAMMATORY PROTEIN 1ALPHA; BETA CHEMOKINE; CCL3L1 PROTEIN, HUMAN; UNCLASSIFIED DRUG;

EID: 52349086807     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0003165     Document Type: Article
Times cited : (20)

References (93)
  • 1
    • 33747132429 scopus 로고    scopus 로고
    • Biology of CCR5 and its role in HIV infection and treatment
    • Lederman MM, Penn-Nicholson A, Cho M, Mosier D (2006) Biology of CCR5 and its role in HIV infection and treatment. Jama 296: 815-826.
    • (2006) Jama , vol.296 , pp. 815-826
    • Lederman, M.M.1    Penn-Nicholson, A.2    Cho, M.3    Mosier, D.4
  • 2
    • 0036772531 scopus 로고    scopus 로고
    • Gene copy number regulates the production of the human chemokine CCL3-L1
    • Townson JR, Barcellos LF, Nibbs RJ (2002) Gene copy number regulates the production of the human chemokine CCL3-L1. Eur J Immunol 32: 3016-3026.
    • (2002) Eur J Immunol , vol.32 , pp. 3016-3026
    • Townson, J.R.1    Barcellos, L.F.2    Nibbs, R.J.3
  • 3
    • 0032745543 scopus 로고    scopus 로고
    • The LD78beta isoform of MIP-1 alpha is the most potent CCR5 agonist and HIV-1-inhibiting chemokine
    • Menten P, Struyf S, Schutyser E, Wuyts A, De Clercq E, et al. (1999) The LD78beta isoform of MIP-1 alpha is the most potent CCR5 agonist and HIV-1-inhibiting chemokine. J Clin Invest 104: R1-5.
    • (1999) J Clin Invest , vol.104
    • Menten, P.1    Struyf, S.2    Schutyser, E.3    Wuyts, A.4    De Clercq, E.5
  • 4
    • 0032798808 scopus 로고    scopus 로고
    • Enhanced anti-HIV-1 activity of CC-chemokine LD78beta, a non-allelic variant of MIP-1alpha/LD78alpha
    • Xin X, Shioda T, Kato A, Liu H, Sakai Y, et al. (1999) Enhanced anti-HIV-1 activity of CC-chemokine LD78beta, a non-allelic variant of MIP-1alpha/LD78alpha. FEBS Lett 457: 219-222.
    • (1999) FEBS Lett , vol.457 , pp. 219-222
    • Xin, X.1    Shioda, T.2    Kato, A.3    Liu, H.4    Sakai, Y.5
  • 5
    • 20044377204 scopus 로고    scopus 로고
    • The influence of CCL3L1 gene-containing segmental duplications on HIV-1/ AIDS susceptibility
    • Gonzalez E, Kulkarni H, Bolivar H, Mangano A, Sanchez R, et al. (2005) The influence of CCL3L1 gene-containing segmental duplications on HIV-1/ AIDS susceptibility. Science 307: 1434-1440.
    • (2005) Science , vol.307 , pp. 1434-1440
    • Gonzalez, E.1    Kulkarni, H.2    Bolivar, H.3    Mangano, A.4    Sanchez, R.5
  • 6
    • 0037124139 scopus 로고    scopus 로고
    • Guidelines for using antiretroviral agents among HIV-infected adults and adolescents. Recommendations of the Panel on Clinical Practices for Treatment of HIV
    • Dybul M, Fauci AS, Bartlett JG, Kaplan JE, Pau AK (2002) Guidelines for using antiretroviral agents among HIV-infected adults and adolescents. Recommendations of the Panel on Clinical Practices for Treatment of HIV. MMWR Recomm Rep 51: 1-55.
    • (2002) MMWR Recomm Rep , vol.51 , pp. 1-55
    • Dybul, M.1    Fauci, A.S.2    Bartlett, J.G.3    Kaplan, J.E.4    Pau, A.K.5
  • 7
    • 3042726798 scopus 로고    scopus 로고
    • Treatment for adult HIV infection: 2004 recommendations of the International AIDS Society-USA Panel
    • Yeni PG, Hammer SM, Hirsch MS, Saag MS, Schechter M, et al. (2004) Treatment for adult HIV infection: 2004 recommendations of the International AIDS Society-USA Panel. Jama 292: 251-265.
    • (2004) Jama , vol.292 , pp. 251-265
    • Yeni, P.G.1    Hammer, S.M.2    Hirsch, M.S.3    Saag, M.S.4    Schechter, M.5
  • 8
    • 52349099228 scopus 로고    scopus 로고
    • Guidelines for the Use of Antiretroviral Agents in HIV-Infected Adults and Adolescents
    • http://aidsinfo.nih.gov (2005) Guidelines for the Use of Antiretroviral Agents in HIV-Infected Adults and Adolescents.
    • (2005)
  • 9
    • 52349110344 scopus 로고    scopus 로고
    • http://www.aidsinfo.nih.gov/ContentFiles/AdultandAdolescentGL.pdf (2008) Guidelines for the use of antiretroviral agents in HIV-1-infected adults and adolescents: Department of Health and Human Services.
    • http://www.aidsinfo.nih.gov/ContentFiles/AdultandAdolescentGL.pdf (2008) Guidelines for the use of antiretroviral agents in HIV-1-infected adults and adolescents: Department of Health and Human Services.
  • 11
    • 9644254355 scopus 로고    scopus 로고
    • Antiretroviral therapy: The "when to start" debates
    • Cohen CJ, Boyle BA (2004) Antiretroviral therapy: the "when to start" debates. Clin Infect Dis 39: 1705-1708.
    • (2004) Clin Infect Dis , vol.39 , pp. 1705-1708
    • Cohen, C.J.1    Boyle, B.A.2
  • 12
    • 0032189130 scopus 로고    scopus 로고
    • CD4 cell count as a surrogate endpoint in HIV clinical trials: A meta-analysis of studies of the AIDS Clinical Trials Group
    • Hughes MD, Daniels MJ, Fischl MA, Kim S, Schooley RT (1998) CD4 cell count as a surrogate endpoint in HIV clinical trials: a meta-analysis of studies of the AIDS Clinical Trials Group. Aids 12: 1823-1832.
    • (1998) Aids , vol.12 , pp. 1823-1832
    • Hughes, M.D.1    Daniels, M.J.2    Fischl, M.A.3    Kim, S.4    Schooley, R.T.5
  • 13
    • 0034632793 scopus 로고    scopus 로고
    • a meta-analysis. HIV Surrogate Marker Collaborative Group
    • Human immunodeficiency virus type 1 RNA level and CD4 count as prognostic markers and surrogate end points
    • Human immunodeficiency virus type 1 RNA level and CD4 count as prognostic markers and surrogate end points: a meta-analysis. HIV Surrogate Marker Collaborative Group. AIDS Res Hum Retroviruses 16: 1123-1133.
    • AIDS Res Hum Retroviruses , vol.16 , pp. 1123-1133
  • 14
    • 0001633495 scopus 로고    scopus 로고
    • Genetic restriction of HIV-1 infection and progression to AIDS by a deletion allele of the CKR5 structural gene. Hemophilia Growth and Development Study, Multicenter AIDS Cohort Study, Multicenter Hemophilia Cohort Study, San Francisco City Cohort, ALIVE Study
    • Dean M, Carrington M, Winkler C, Huttley GA, Smith MW, et al. (1996) Genetic restriction of HIV-1 infection and progression to AIDS by a deletion allele of the CKR5 structural gene. Hemophilia Growth and Development Study, Multicenter AIDS Cohort Study, Multicenter Hemophilia Cohort Study, San Francisco City Cohort, ALIVE Study. Science 273: 1856-1862.
    • (1996) Science , vol.273 , pp. 1856-1862
    • Dean, M.1    Carrington, M.2    Winkler, C.3    Huttley, G.A.4    Smith, M.W.5
  • 15
    • 0032484088 scopus 로고    scopus 로고
    • Genetic acceleration of AIDS progression by a promoter variant of CCR5
    • Martin MP, Dean M, Smith MW, Winkler C, Gerrard B, et al. (1998) Genetic acceleration of AIDS progression by a promoter variant of CCR5. Science 282: 1907-1911.
    • (1998) Science , vol.282 , pp. 1907-1911
    • Martin, M.P.1    Dean, M.2    Smith, M.W.3    Winkler, C.4    Gerrard, B.5
  • 16
    • 2642563503 scopus 로고    scopus 로고
    • Human genes that limit AIDS
    • O'Brien SJ, Nelson GW (2004) Human genes that limit AIDS. Nat Genet 36: 565-574.
    • (2004) Nat Genet , vol.36 , pp. 565-574
    • O'Brien, S.J.1    Nelson, G.W.2
  • 17
    • 12444282714 scopus 로고    scopus 로고
    • Influence of host genetic variation on susceptibility to HIV type 1 infection
    • Kaslow RA, Dorak T, Tang JJ (2005) Influence of host genetic variation on susceptibility to HIV type 1 infection. J Infect Dis 191 Suppl 1: S68-77.
    • (2005) J Infect Dis , vol.191 , Issue.SUPPL. 1
    • Kaslow, R.A.1    Dorak, T.2    Tang, J.J.3
  • 18
    • 13044263875 scopus 로고    scopus 로고
    • Gonzalez E, Bamshad M, Sato N, Mummidi S, Dhanda R, et al. (1999) Race-specific HIV-1 disease-modifying effects associated with CCR5 haplotypes. Proc Natl Arad Sci U S A 96: 12004-12009.
    • Gonzalez E, Bamshad M, Sato N, Mummidi S, Dhanda R, et al. (1999) Race-specific HIV-1 disease-modifying effects associated with CCR5 haplotypes. Proc Natl Arad Sci U S A 96: 12004-12009.
  • 19
    • 0035370348 scopus 로고    scopus 로고
    • Concordance between the CC chemokine receptor 5 genetic determinants that alter risks of transmission and disease progression in children exposed perinatally to human immunodeficiency virus
    • Mangano A, Gonzalez E, Dhanda R, Catano G, Bamshad M, et al. (2001) Concordance between the CC chemokine receptor 5 genetic determinants that alter risks of transmission and disease progression in children exposed perinatally to human immunodeficiency virus. J Infect Dis 183: 1574-1585.
    • (2001) J Infect Dis , vol.183 , pp. 1574-1585
    • Mangano, A.1    Gonzalez, E.2    Dhanda, R.3    Catano, G.4    Bamshad, M.5
  • 20
    • 34548670468 scopus 로고    scopus 로고
    • CCL3L1 and CCR5 influence cell-mediated immunity and affect HIV-AIDS pathogenesis via viral entry-independent mechanisms
    • Dolan MJ, Kulkarni H, Camargo JF, He W, Smith A, et al. (2007) CCL3L1 and CCR5 influence cell-mediated immunity and affect HIV-AIDS pathogenesis via viral entry-independent mechanisms. Nat Inummol 8: 1324-1336.
    • (2007) Nat Inummol , vol.8 , pp. 1324-1336
    • Dolan, M.J.1    Kulkarni, H.2    Camargo, J.F.3    He, W.4    Smith, A.5
  • 21
    • 0034122740 scopus 로고    scopus 로고
    • Effect of chemokine receptor gene polymorphisms on the response to potent antiretroviral therapy
    • O'Brien TR, McDermott DH, Ioannidis JP, Carrington M, Murphy PM, et al. (2000) Effect of chemokine receptor gene polymorphisms on the response to potent antiretroviral therapy. Aids 14: 821-826.
    • (2000) Aids , vol.14 , pp. 821-826
    • O'Brien, T.R.1    McDermott, D.H.2    Ioannidis, J.P.3    Carrington, M.4    Murphy, P.M.5
  • 22
    • 42049092144 scopus 로고    scopus 로고
    • Hunt P, Carrington M (2008) Host genetic determinants of HIV pathogenesis: an immunologic perspective. Immune correlates of protection, activation and exhaustion. Current Opinion in HIV & AIDS 3: 342-348.
    • Hunt P, Carrington M (2008) Host genetic determinants of HIV pathogenesis: an immunologic perspective. Immune correlates of protection, activation and exhaustion. Current Opinion in HIV & AIDS 3: 342-348.
  • 23
    • 41849143395 scopus 로고    scopus 로고
    • CCL3L1-CCR5 genotype influences durability of immune recovery during antiretroviral therapy of HIV-1-infected individuals
    • Ahuja SK, Kulkarni H, Catano C, Agan BK, Camargo JF, et al. (2008) CCL3L1-CCR5 genotype influences durability of immune recovery during antiretroviral therapy of HIV-1-infected individuals. Nat Med 14: 413-420.
    • (2008) Nat Med , vol.14 , pp. 413-420
    • Ahuja, S.K.1    Kulkarni, H.2    Catano, C.3    Agan, B.K.4    Camargo, J.F.5
  • 24
    • 0038581912 scopus 로고    scopus 로고
    • The influence of HLA genotype on AIDS
    • Carrington M, O'Brien SJ (2003) The influence of HLA genotype on AIDS. Annu Rev Med 54: 535-551.
    • (2003) Annu Rev Med , vol.54 , pp. 535-551
    • Carrington, M.1    O'Brien, S.J.2
  • 25
    • 40349096074 scopus 로고    scopus 로고
    • Host factors associated with outcome from primary human immunodeficiency virus-1 infection. Current Opinion in HIV & AIDS
    • Telenti A, Carrington M (2008) Host factors associated with outcome from primary human immunodeficiency virus-1 infection. Current Opinion in HIV & AIDS 3: 28-35.
    • (2008) , vol.3 , pp. 28-35
    • Telenti, A.1    Carrington, M.2
  • 27
    • 22544453346 scopus 로고    scopus 로고
    • Characteristics, determinants, and clinical relevance of CD4 T cell recovery to <500 cells/microL in HIV type 1-infected individuals receiving potent antiretroviral therapy
    • Kaufmann GR, Furrer H, Ledergerber B, Perrin L, Opravil M, et al. (2005) Characteristics, determinants, and clinical relevance of CD4 T cell recovery to <500 cells/microL in HIV type 1-infected individuals receiving potent antiretroviral therapy. Clin Infect Dis 41: 361-372.
    • (2005) Clin Infect Dis , vol.41 , pp. 361-372
    • Kaufmann, G.R.1    Furrer, H.2    Ledergerber, B.3    Perrin, L.4    Opravil, M.5
  • 28
    • 0041631056 scopus 로고    scopus 로고
    • Factors associated with a reduced CD4 lymphocyte count response to HAART despite full viral suppression in the EuroSIDA study
    • Florence E, Lundgren J, Dreezen C, Fisher M, Kirk O, et al. (2003) Factors associated with a reduced CD4 lymphocyte count response to HAART despite full viral suppression in the EuroSIDA study. HIV Med 4: 255-262.
    • (2003) HIV Med , vol.4 , pp. 255-262
    • Florence, E.1    Lundgren, J.2    Dreezen, C.3    Fisher, M.4    Kirk, O.5
  • 29
    • 33846439783 scopus 로고    scopus 로고
    • CD4+ cell count 6 years after commencement of highly active antiretroviral therapy in persons with sustained virologic suppression
    • Moore RD, Keruly JC (2007) CD4+ cell count 6 years after commencement of highly active antiretroviral therapy in persons with sustained virologic suppression. Clin Infect Dis 44: 441-446.
    • (2007) Clin Infect Dis , vol.44 , pp. 441-446
    • Moore, R.D.1    Keruly, J.C.2
  • 30
    • 0034687071 scopus 로고    scopus 로고
    • Clinical outcome of patients with HIV-1 infection according to immunologic and virologic response after 6 months of highly active antiretroviral therapy
    • Grabar S, Le Moing V, Goujard C, Leport C, Kazatchkine MD, et al. (2000) Clinical outcome of patients with HIV-1 infection according to immunologic and virologic response after 6 months of highly active antiretroviral therapy. Ann Intern Med 133: 401-410.
    • (2000) Ann Intern Med , vol.133 , pp. 401-410
    • Grabar, S.1    Le Moing, V.2    Goujard, C.3    Leport, C.4    Kazatchkine, M.D.5
  • 31
    • 0035362495 scopus 로고    scopus 로고
    • Increase and plateau of CD4 T-cell counts in the 3(1/2) years after initiation of potent antiretroviral therapy
    • Tarwater PM, Margolick JB, Jin J, Phair JP, Detels R, et al. (2001) Increase and plateau of CD4 T-cell counts in the 3(1/2) years after initiation of potent antiretroviral therapy. J Acquit Immune Defic Syndr 27: 168-175.
    • (2001) J Acquit Immune Defic Syndr , vol.27 , pp. 168-175
    • Tarwater, P.M.1    Margolick, J.B.2    Jin, J.3    Phair, J.P.4    Detels, R.5
  • 32
    • 0041326880 scopus 로고    scopus 로고
    • Continued CD4 cell count increases in HIV-infected adults experiencing 4 years of viral suppression on antiretroviral therapy
    • Hunt PW, Deeks SC, Rodriguez B, Valdez H, Shade SB, et al. (2003) Continued CD4 cell count increases in HIV-infected adults experiencing 4 years of viral suppression on antiretroviral therapy. Aids 17: 1907-1915.
    • (2003) Aids , vol.17 , pp. 1907-1915
    • Hunt, P.W.1    Deeks, S.C.2    Rodriguez, B.3    Valdez, H.4    Shade, S.B.5
  • 33
    • 27444439823 scopus 로고    scopus 로고
    • Discordant immunologic and virologic responses to highly active antiretroviral therapy are associated with increased mortality and poor adherence to therapy
    • Moore DM, Hogg RS, Yip B, Wood E, Tyndall M, et al. (2005) Discordant immunologic and virologic responses to highly active antiretroviral therapy are associated with increased mortality and poor adherence to therapy. J Acquir Immune Defic Syndr 40: 288-293.
    • (2005) J Acquir Immune Defic Syndr , vol.40 , pp. 288-293
    • Moore, D.M.1    Hogg, R.S.2    Yip, B.3    Wood, E.4    Tyndall, M.5
  • 34
    • 0037183954 scopus 로고    scopus 로고
    • Limited immune restoration after 3 years' suppression of HIV-1 replication in patients with moderately advanced disease
    • Valdez H, Connick E, Smith KY, Lederman MM, Bosch RJ, et al. (2002) Limited immune restoration after 3 years' suppression of HIV-1 replication in patients with moderately advanced disease. Aids 16: 1859-1866.
    • (2002) Aids , vol.16 , pp. 1859-1866
    • Valdez, H.1    Connick, E.2    Smith, K.Y.3    Lederman, M.M.4    Bosch, R.J.5
  • 35
    • 33748039441 scopus 로고    scopus 로고
    • Factors associated with the development of opportunistic infections in HIV-1-infected adults with high CD4+ cell counts: A EuroSIDA study
    • Podlekareva D, Mocroft A, Dragsted UB, Ledergerber B, Beniowski M, et al. (2006) Factors associated with the development of opportunistic infections in HIV-1-infected adults with high CD4+ cell counts: a EuroSIDA study. J Infect Dis 194: 636-641.
    • (2006) J Infect Dis , vol.194 , pp. 636-641
    • Podlekareva, D.1    Mocroft, A.2    Dragsted, U.B.3    Ledergerber, B.4    Beniowski, M.5
  • 36
    • 52349104156 scopus 로고    scopus 로고
    • http://www.clinicaltrials.gov.
  • 37
    • 8244227329 scopus 로고    scopus 로고
    • Inherited resistance to HIV-1 conferred by an inactivating mutation in CC chemokine receptor 5: Studies in populations with contrasting clinical phenotypes, defined racial background, and quantified risk
    • Zimmerman PA, Buckler-White A, Alkhatib G, Spalding T, Kubofcik J, et al. (1997) Inherited resistance to HIV-1 conferred by an inactivating mutation in CC chemokine receptor 5: studies in populations with contrasting clinical phenotypes, defined racial background, and quantified risk. Mol Med 3: 23-36.
    • (1997) Mol Med , vol.3 , pp. 23-36
    • Zimmerman, P.A.1    Buckler-White, A.2    Alkhatib, G.3    Spalding, T.4    Kubofcik, J.5
  • 38
    • 0032511573 scopus 로고    scopus 로고
    • CCR5 promoter polymorphism and HIV-1 disease progression. Multicenter AIDS Cohort Study (MACS)
    • McDermott DH, Zimmerman PA, Guignard F, Kleeberger CA, Leitman SF, et al. (1998) CCR5 promoter polymorphism and HIV-1 disease progression. Multicenter AIDS Cohort Study (MACS). Lancet 352: 866-870.
    • (1998) Lancet , vol.352 , pp. 866-870
    • McDermott, D.H.1    Zimmerman, P.A.2    Guignard, F.3    Kleeberger, C.A.4    Leitman, S.F.5
  • 39
    • 24644465001 scopus 로고    scopus 로고
    • Combined effect of CCR5-Delta32 heterozygosity and the CCR5 promoter polymorphism -2459 A/G on CCR5 expression and resistance to human immunodeficiency virus type 1 transmission
    • Hladik F, Liu H, Speelmon E, Livingston-Rosanoff D, Wilson S, et al. (2005) Combined effect of CCR5-Delta32 heterozygosity and the CCR5 promoter polymorphism -2459 A/G on CCR5 expression and resistance to human immunodeficiency virus type 1 transmission. J Virol 79: 11677-11684.
    • (2005) J Virol , vol.79 , pp. 11677-11684
    • Hladik, F.1    Liu, H.2    Speelmon, E.3    Livingston-Rosanoff, D.4    Wilson, S.5
  • 40
    • 0033603784 scopus 로고    scopus 로고
    • Association of the CCR5delta32 mutation with improved response to antiretroviral therapy
    • Valdez H, Purvis SF, Lederman MM, Fillingame M, Zimmerman PA (1999) Association of the CCR5delta32 mutation with improved response to antiretroviral therapy. Jama 282: 734.
    • (1999) Jama , vol.282 , pp. 734
    • Valdez, H.1    Purvis, S.F.2    Lederman, M.M.3    Fillingame, M.4    Zimmerman, P.A.5
  • 42
    • 34249889344 scopus 로고    scopus 로고
    • Cell surface expression of CCR5 and other host factors influence the inhibition of HIV-1 infection of human lymphocytes by CCR5 ligands
    • Ketas TJ, Kuhmann SE, Palmer A, Zurita J, He W, et al. (2007) Cell surface expression of CCR5 and other host factors influence the inhibition of HIV-1 infection of human lymphocytes by CCR5 ligands. Virology 364: 281-290.
    • (2007) Virology , vol.364 , pp. 281-290
    • Ketas, T.J.1    Kuhmann, S.E.2    Palmer, A.3    Zurita, J.4    He, W.5
  • 44
    • 35348847181 scopus 로고    scopus 로고
    • Copy number variations of CCL3L1 and long-term prognosis of HIV-1 infection in asymptomatic HIV-infected Japanese with hemophilia
    • Nakajima T, Ohtani H, Naruse T, Shibata H, Mimaya JI, et al. (2007) Copy number variations of CCL3L1 and long-term prognosis of HIV-1 infection in asymptomatic HIV-infected Japanese with hemophilia. Immunogenetics 59: 793-798.
    • (2007) Immunogenetics , vol.59 , pp. 793-798
    • Nakajima, T.1    Ohtani, H.2    Naruse, T.3    Shibata, H.4    Mimaya, J.I.5
  • 45
    • 34547794820 scopus 로고    scopus 로고
    • African infants' CCL3 gene copies influence perinatal HIV transmission in the absence of maternal nevirapine
    • Kuhn L, Schramm DB, Donninger S, Meddows-Taylor S, Coovadia AH, et al. (2007) African infants' CCL3 gene copies influence perinatal HIV transmission in the absence of maternal nevirapine. Aids 21: 1753-1761.
    • (2007) Aids , vol.21 , pp. 1753-1761
    • Kuhn, L.1    Schramm, D.B.2    Donninger, S.3    Meddows-Taylor, S.4    Coovadia, A.H.5
  • 46
    • 33745608710 scopus 로고    scopus 로고
    • Reduced ability of newborns to produce CCL3 is associated with increased susceptibility to perinatal human immunodeficiency virus 1 transmission
    • Meddows-Taylor S, Donninger SL, Paximadis M, Schramm DB, Anthony FS, et al. (2006) Reduced ability of newborns to produce CCL3 is associated with increased susceptibility to perinatal human immunodeficiency virus 1 transmission. J Gen Virol 87: 2055-2065.
    • (2006) J Gen Virol , vol.87 , pp. 2055-2065
    • Meddows-Taylor, S.1    Donninger, S.L.2    Paximadis, M.3    Schramm, D.B.4    Anthony, F.S.5
  • 47
    • 47049091470 scopus 로고    scopus 로고
    • Host CCL3L1 gene copy number in relation to HIV-1-specific CD4+ and CD8+ T-cell responses and viral load in South African women
    • Shalekoff S, Meddows-Taylor S, Schramm DB, Donninger SL, Gray GE, et al. (2008) Host CCL3L1 gene copy number in relation to HIV-1-specific CD4+ and CD8+ T-cell responses and viral load in South African women. J Acquir Immune Defic Syndr 48: 245-254.
    • (2008) J Acquir Immune Defic Syndr , vol.48 , pp. 245-254
    • Shalekoff, S.1    Meddows-Taylor, S.2    Schramm, D.B.3    Donninger, S.L.4    Gray, G.E.5
  • 48
    • 0033012134 scopus 로고    scopus 로고
    • Molecular mechanisms of CD8+ T cell-mediated delayed hypersensitivity: Implications for allergies, asthma, and autoimmunity
    • Kalish RS, Askenase PW (1999) Molecular mechanisms of CD8+ T cell-mediated delayed hypersensitivity: implications for allergies, asthma, and autoimmunity. J Allergy Clin Immunol 103: 192-199.
    • (1999) J Allergy Clin Immunol , vol.103 , pp. 192-199
    • Kalish, R.S.1    Askenase, P.W.2
  • 49
    • 0021347789 scopus 로고
    • Multitest CMI for standardized measurement of delayed cutaneous hypersensitivity and cell-mediated immunity. Normal values and proposed scoring system for healthy adults in the U.S.A
    • Kniker WT, Anderson CT, McBryde JL, Roumiantzeff M, Lesourd B (1984) Multitest CMI for standardized measurement of delayed cutaneous hypersensitivity and cell-mediated immunity. Normal values and proposed scoring system for healthy adults in the U.S.A. Ann Allergy 52: 75-82.
    • (1984) Ann Allergy , vol.52 , pp. 75-82
    • Kniker, W.T.1    Anderson, C.T.2    McBryde, J.L.3    Roumiantzeff, M.4    Lesourd, B.5
  • 50
    • 0027361830 scopus 로고
    • The prognostic utility of delayed-type hypersensitivity skin testing in the evaluation of HIV-infected patients. Military Medical Consortium for Applied Retroviral Research
    • Birx DL, Brundage J, Larson K, Engler R, Smith L, et al. (1993) The prognostic utility of delayed-type hypersensitivity skin testing in the evaluation of HIV-infected patients. Military Medical Consortium for Applied Retroviral Research. J Acquir Immune Defic Syndr 6: 1248-1257.
    • (1993) J Acquir Immune Defic Syndr , vol.6 , pp. 1248-1257
    • Birx, D.L.1    Brundage, J.2    Larson, K.3    Engler, R.4    Smith, L.5
  • 51
    • 0028344909 scopus 로고
    • Delayed-type hypersensitivity skin tests are an independent predictor of human immunodeficiency virus disease progression. Department of Veterans Affairs Cooperative Study Group
    • Gordin FM, Harrigan PM, Klimas NG, Zolla-Pazner SB, Simberkoff MS, et al. (1994) Delayed-type hypersensitivity skin tests are an independent predictor of human immunodeficiency virus disease progression. Department of Veterans Affairs Cooperative Study Group. J Infect Dis 169: 893-897.
    • (1994) J Infect Dis , vol.169 , pp. 893-897
    • Gordin, F.M.1    Harrigan, P.M.2    Klimas, N.G.3    Zolla-Pazner, S.B.4    Simberkoff, M.S.5
  • 52
    • 0029031796 scopus 로고
    • In vitro T cell function, delayed-type hypersensitivity skin testing, and CD4+ T cell subset phenotyping independently predict survival time in patients infected with human immunodeficiency virus
    • Dolan MJ, Clerici M, Blatt SP, Hendrix CW, Melcher GP, et al. (1995) In vitro T cell function, delayed-type hypersensitivity skin testing, and CD4+ T cell subset phenotyping independently predict survival time in patients infected with human immunodeficiency virus. J Infect Dis 172: 79-87.
    • (1995) J Infect Dis , vol.172 , pp. 79-87
    • Dolan, M.J.1    Clerici, M.2    Blatt, S.P.3    Hendrix, C.W.4    Melcher, G.P.5
  • 53
    • 17344367358 scopus 로고    scopus 로고
    • In vivo delayed-type hypersensitivity skin test anergy in human immunodeficiency virus type 1 infection is associated with T cell nonresponsiveness in vitro
    • Maas JJ, Roos MT, Keet IP, Mensen EA, Krol, et al. (1998) In vivo delayed-type hypersensitivity skin test anergy in human immunodeficiency virus type 1 infection is associated with T cell nonresponsiveness in vitro. J Infect Dis 178: 1024-1029.
    • (1998) J Infect Dis , vol.178 , pp. 1024-1029
    • Maas, J.J.1    Roos, M.T.2    Keet, I.P.3    Mensen, E.A.4    Krol5
  • 54
    • 34247352040 scopus 로고    scopus 로고
    • Evolutionary and biomedical insights from the rhesus macaque genome
    • Gibbs RA, Rogers J, Katze MG, Bumgarner R, Weinstock GM, et al. (2007) Evolutionary and biomedical insights from the rhesus macaque genome. Science 316: 222-234.
    • (2007) Science , vol.316 , pp. 222-234
    • Gibbs, R.A.1    Rogers, J.2    Katze, M.G.3    Bumgarner, R.4    Weinstock, G.M.5
  • 55
    • 34548689151 scopus 로고    scopus 로고
    • Human immunodeficiency virus controllers: Mechanisms of durable virus control in the absence of antiretroviral therapy
    • Deeks SG, Walker BD (2007) Human immunodeficiency virus controllers: mechanisms of durable virus control in the absence of antiretroviral therapy. Immunity 27: 406-416.
    • (2007) Immunity , vol.27 , pp. 406-416
    • Deeks, S.G.1    Walker, B.D.2
  • 56
    • 19244384846 scopus 로고    scopus 로고
    • Global survey ofgenetic variation in CCR5, RANTES, and MIP-1alpha: Impact on the epidemiology of the HIV-1 pandemic
    • Gonzalez E, Dhanda R, Bamshad M, Mummidi S, Geevarghese R, et al. (2001) Global survey ofgenetic variation in CCR5, RANTES, and MIP-1alpha: impact on the epidemiology of the HIV-1 pandemic. Proc Natl Acad Sci U S A 98: 5199-5204.
    • (2001) Proc Natl Acad Sci U S A , vol.98 , pp. 5199-5204
    • Gonzalez, E.1    Dhanda, R.2    Bamshad, M.3    Mummidi, S.4    Geevarghese, R.5
  • 57
    • 0037108817 scopus 로고    scopus 로고
    • HIV-1 infection and AIDS dementia are influenced by a mutant MCP-1 allele linked to increased monocyte infiltration of tissues and MCP-1 levels
    • Gonzalez E, Rovin BH, Sen L, Cooke G, Dhanda R, et al. (2002) HIV-1 infection and AIDS dementia are influenced by a mutant MCP-1 allele linked to increased monocyte infiltration of tissues and MCP-1 levels. Proc Natl Acad Sci U S A 99: 13795-13800.
    • (2002) Proc Natl Acad Sci U S A , vol.99 , pp. 13795-13800
    • Gonzalez, E.1    Rovin, B.H.2    Sen, L.3    Cooke, G.4    Dhanda, R.5
  • 58
    • 33746192133 scopus 로고    scopus 로고
    • Effectiveness of highly-active antiretroviral therapy by race/ ethnicity
    • Silverberg MJ, Wegner SA, Milazzo MJ, McKaig RG, Williams CF, et al. (2006) Effectiveness of highly-active antiretroviral therapy by race/ ethnicity. Aids 20: 1531-1538.
    • (2006) Aids , vol.20 , pp. 1531-1538
    • Silverberg, M.J.1    Wegner, S.A.2    Milazzo, M.J.3    McKaig, R.G.4    Williams, C.F.5
  • 59
    • 0031896226 scopus 로고    scopus 로고
    • Clinical utility of likelihood ratios
    • Gallagher EJ (1998) Clinical utility of likelihood ratios. Ann Emerg Med 31: 391-397.
    • (1998) Ann Emerg Med , vol.31 , pp. 391-397
    • Gallagher, E.J.1
  • 60
    • 0036599514 scopus 로고    scopus 로고
    • Decision rule and utility of routine urine toxicology screening of trauma patients
    • Langdorf MI, Rudkin SE, Dellota K, Fox JC, Munden S (2002) Decision rule and utility of routine urine toxicology screening of trauma patients. Eur J Emerg Med 9: 115-121.
    • (2002) Eur J Emerg Med , vol.9 , pp. 115-121
    • Langdorf, M.I.1    Rudkin, S.E.2    Dellota, K.3    Fox, J.C.4    Munden, S.5
  • 61
    • 0348220947 scopus 로고    scopus 로고
    • Classification and regression tree analysis in public health: Methodological review and comparison with logistic regression
    • Lemon SC, Roy J, Clark MA, Friedmann PD, Rakowski W (2003) Classification and regression tree analysis in public health: methodological review and comparison with logistic regression. Ann Behav Med 26: 172-181.
    • (2003) Ann Behav Med , vol.26 , pp. 172-181
    • Lemon, S.C.1    Roy, J.2    Clark, M.A.3    Friedmann, P.D.4    Rakowski, W.5
  • 62
    • 0347093538 scopus 로고    scopus 로고
    • Selecting prescreening items for early intervention trials of dementia-a case study
    • Li L, Huang J, Sun S, Shen J, Unverzagt FW, et al. (2004) Selecting prescreening items for early intervention trials of dementia-a case study. Stat Med 23: 271-283.
    • (2004) Stat Med , vol.23 , pp. 271-283
    • Li, L.1    Huang, J.2    Sun, S.3    Shen, J.4    Unverzagt, F.W.5
  • 63
    • 0035227182 scopus 로고    scopus 로고
    • Classification methods for confronting heterogeneity
    • Province MA, Shannon WD, Rao DC (2001) Classification methods for confronting heterogeneity. Adv Genet 42: 273-286.
    • (2001) Adv Genet , vol.42 , pp. 273-286
    • Province, M.A.1    Shannon, W.D.2    Rao, D.C.3
  • 64
    • 0141502409 scopus 로고    scopus 로고
    • A novel approach toward development of a rapid blood test for breast cancer
    • Vlahou A, Laronga C, Wilson L, Gregory B, Fournier K, et al. (2003) A novel approach toward development of a rapid blood test for breast cancer. Clin Breast Cancer 4: 203-209.
    • (2003) Clin Breast Cancer , vol.4 , pp. 203-209
    • Vlahou, A.1    Laronga, C.2    Wilson, L.3    Gregory, B.4    Fournier, K.5
  • 65
    • 10744223487 scopus 로고    scopus 로고
    • The impact of early immune destruction on the kinetics of postacute viral replication in rhesus monkey infected with the simian-human immunodeficiency virus 89.6P
    • Zhang ZQ, Schleif WA, Casimiro DR, Handt L, Chen M, et al. (2004) The impact of early immune destruction on the kinetics of postacute viral replication in rhesus monkey infected with the simian-human immunodeficiency virus 89.6P. Virology 320: 75-84.
    • (2004) Virology , vol.320 , pp. 75-84
    • Zhang, Z.Q.1    Schleif, W.A.2    Casimiro, D.R.3    Handt, L.4    Chen, M.5
  • 66
    • 1842296349 scopus 로고    scopus 로고
    • Plasma viral load and CD4+ lymphocytes as prognostic markers of HIV-1 infection
    • Mellors JW, Munoz A, Giorgi JV, Margolick JB, Tassoni CJ, et al. (1997) Plasma viral load and CD4+ lymphocytes as prognostic markers of HIV-1 infection. Ann Intern Med 126: 946-954.
    • (1997) Ann Intern Med , vol.126 , pp. 946-954
    • Mellors, J.W.1    Munoz, A.2    Giorgi, J.V.3    Margolick, J.B.4    Tassoni, C.J.5
  • 67
    • 17344384248 scopus 로고    scopus 로고
    • Containment of simian immunodeficiency virus infection: Cellular immune responses and protection from rechallenge following transient postinoculation antiretroviral treatment
    • Lifson JD, Rossio JL, Arnaout R, Li L, Parks TL, et al. (2000) Containment of simian immunodeficiency virus infection: cellular immune responses and protection from rechallenge following transient postinoculation antiretroviral treatment. J Virol 74: 2584-2593.
    • (2000) J Virol , vol.74 , pp. 2584-2593
    • Lifson, J.D.1    Rossio, J.L.2    Arnaout, R.3    Li, L.4    Parks, T.L.5
  • 68
    • 0034705597 scopus 로고    scopus 로고
    • Evolution of human and non-human primate CC chemokine receptor 5 gene and mRNA. Potential roles for haplotype and mRNA diversity, differential haplotype-specific transcriptional activity, and altered transcription factor binding to polymorphic nucleotides in the pathogenesis of HIV-1 and simian immunodeficiency virus
    • Mummidi S, Bamshad M, Ahuja SS, Gonzalez E, Feuillet PM, et al. (2000) Evolution of human and non-human primate CC chemokine receptor 5 gene and mRNA. Potential roles for haplotype and mRNA diversity, differential haplotype-specific transcriptional activity, and altered transcription factor binding to polymorphic nucleotides in the pathogenesis of HIV-1 and simian immunodeficiency virus. J Biel Chem 275: 18946-18961.
    • (2000) J Biel Chem , vol.275 , pp. 18946-18961
    • Mummidi, S.1    Bamshad, M.2    Ahuja, S.S.3    Gonzalez, E.4    Feuillet, P.M.5
  • 69
    • 33748512788 scopus 로고    scopus 로고
    • CCR5 expression and duration of high risk sexual activity among HIV-seronegative men who have sex with men
    • Thomas SM, Tse DB, Ketner DS, Rochford G, Meyer DA, et al. (2006) CCR5 expression and duration of high risk sexual activity among HIV-seronegative men who have sex with men. Aids 20: 1879-1883.
    • (2006) Aids , vol.20 , pp. 1879-1883
    • Thomas, S.M.1    Tse, D.B.2    Ketner, D.S.3    Rochford, G.4    Meyer, D.A.5
  • 70
    • 0141565366 scopus 로고    scopus 로고
    • CCR5 promoter polymorphism determines macrophage CCR5 density and magnitude of HIV-1 propagation in vitro
    • Salkowitz JR, Bruse SE, Meyerson H, Valdez H, Mosier DE, et al. (2003) CCR5 promoter polymorphism determines macrophage CCR5 density and magnitude of HIV-1 propagation in vitro. Clin Immumol 108: 234-240.
    • (2003) Clin Immumol , vol.108 , pp. 234-240
    • Salkowitz, J.R.1    Bruse, S.E.2    Meyerson, H.3    Valdez, H.4    Mosier, D.E.5
  • 71
    • 0038153897 scopus 로고    scopus 로고
    • R5 HIV productively infects Langerhans cells, and infection levels are regulated by compound CCR5 polymorphisms
    • Kawamura T, Gulden FO, Sugaya M, McNamara DT, Borris DL, et al. (2003) R5 HIV productively infects Langerhans cells, and infection levels are regulated by compound CCR5 polymorphisms. Proc Natl Acad Sci U S A 100: 8401-8406.
    • (2003) Proc Natl Acad Sci U S A , vol.100 , pp. 8401-8406
    • Kawamura, T.1    Gulden, F.O.2    Sugaya, M.3    McNamara, D.T.4    Borris, D.L.5
  • 72
    • 0042915961 scopus 로고    scopus 로고
    • Low CD4+ T-cell surface CCR5 density as a cause of resistance to in vivo HIV-1 infection
    • Reynes J, Baillat V, Portales P, Clot J, Corbeau P (2003) Low CD4+ T-cell surface CCR5 density as a cause of resistance to in vivo HIV-1 infection. J Acquir Immune Defic Syndr 34: 114-116.
    • (2003) J Acquir Immune Defic Syndr , vol.34 , pp. 114-116
    • Reynes, J.1    Baillat, V.2    Portales, P.3    Clot, J.4    Corbeau, P.5
  • 73
    • 0034031324 scopus 로고    scopus 로고
    • CD4+ T cell surface CCR5 density as a determining factor of virus load in persons infected with human immunodeficiency virus type 1
    • Reynes J, Portales P, Segondy M, Baillat V, Andre P, et al. (2000) CD4+ T cell surface CCR5 density as a determining factor of virus load in persons infected with human immunodeficiency virus type 1. J Infect Dis 181: 927-932.
    • (2000) J Infect Dis , vol.181 , pp. 927-932
    • Reynes, J.1    Portales, P.2    Segondy, M.3    Baillat, V.4    Andre, P.5
  • 74
    • 0035822952 scopus 로고    scopus 로고
    • CD4 T cell surface CCR5 density as a host factor in HIV-1 disease progression
    • Reynes J, Portales P, Segondy M, Baillat V, Andre P, et al. (2001) CD4 T cell surface CCR5 density as a host factor in HIV-1 disease progression. Aids 15: 1627-1634.
    • (2001) Aids , vol.15 , pp. 1627-1634
    • Reynes, J.1    Portales, P.2    Segondy, M.3    Baillat, V.4    Andre, P.5
  • 75
    • 0037090331 scopus 로고    scopus 로고
    • Response to treatment and disease progression linked to CD4+ T cell surface CC chemokine receptor 5 density in human immunodeficiency virus type 1 vertical infection
    • Gervaix A, Nicolas J, Portales P, Posfay-Barbe K, Wyler CA, et al. (2002) Response to treatment and disease progression linked to CD4+ T cell surface CC chemokine receptor 5 density in human immunodeficiency virus type 1 vertical infection. J Infect Dis 185: 1055-1061.
    • (2002) J Infect Dis , vol.185 , pp. 1055-1061
    • Gervaix, A.1    Nicolas, J.2    Portales, P.3    Posfay-Barbe, K.4    Wyler, C.A.5
  • 76
    • 33750540192 scopus 로고    scopus 로고
    • The immunological response to highly active antiretroviral therapy is linked to CD4+ T-cell surface CCR5 density
    • Vincent T, Portales P, Baillat V, Eden A, CIot J, et al. (2006) The immunological response to highly active antiretroviral therapy is linked to CD4+ T-cell surface CCR5 density. J Acquir Immune Defic Syndr 43: 377-378.
    • (2006) J Acquir Immune Defic Syndr , vol.43 , pp. 377-378
    • Vincent, T.1    Portales, P.2    Baillat, V.3    Eden, A.4    CIot, J.5
  • 77
    • 0029942460 scopus 로고    scopus 로고
    • Chemokines and T lymphocyte activation: I. Beta chemokines costimulate human T lymphocyte activalion in vitro
    • Taub DD, Turcovski-Corrales SM, Key ML, Longo DL, Murphy WJ (1996) Chemokines and T lymphocyte activation: I. Beta chemokines costimulate human T lymphocyte activalion in vitro. J Immonul 156: 2095-2103.
    • (1996) J Immonul , vol.156 , pp. 2095-2103
    • Taub, D.D.1    Turcovski-Corrales, S.M.2    Key, M.L.3    Longo, D.L.4    Murphy, W.J.5
  • 78
    • 0031131879 scopus 로고    scopus 로고
    • Differential CC chemokine-induced enhancement of T helper cell cytokine production
    • Karpus WJ, Lukacs NW, Kennedy KJ, Smith WS, Hurst SD, et al. (1997) Differential CC chemokine-induced enhancement of T helper cell cytokine production. J Immunol 158: 4129-4136.
    • (1997) J Immunol , vol.158 , pp. 4129-4136
    • Karpus, W.J.1    Lukacs, N.W.2    Kennedy, K.J.3    Smith, W.S.4    Hurst, S.D.5
  • 79
    • 0034667785 scopus 로고    scopus 로고
    • Macrophage-derived dendritic cells have strong Th1-polarizing potential mediated by beta-chemokines rather than IL-12
    • Zou W, Borvak J, Marches F, Wei S, Galanaud P, et al. (2000) Macrophage-derived dendritic cells have strong Th1-polarizing potential mediated by beta-chemokines rather than IL-12. J Immunol 165: 4388-4396.
    • (2000) J Immunol , vol.165 , pp. 4388-4396
    • Zou, W.1    Borvak, J.2    Marches, F.3    Wei, S.4    Galanaud, P.5
  • 80
    • 0033938121 scopus 로고    scopus 로고
    • Beta-chemokines inhibit activation-induced death of lymphocytes from HIV-infected individuals
    • Pinto LA, Williams MS, Dolan MJ, Henkart PA, Shearer GM (2000) Beta-chemokines inhibit activation-induced death of lymphocytes from HIV-infected individuals. Eur J Immunol 30: 2048-2055.
    • (2000) Eur J Immunol , vol.30 , pp. 2048-2055
    • Pinto, L.A.1    Williams, M.S.2    Dolan, M.J.3    Henkart, P.A.4    Shearer, G.M.5
  • 81
    • 0035260758 scopus 로고    scopus 로고
    • Chemokines as regulators of T cell differentiation
    • Luther SA, Cyster JG (2001) Chemokines as regulators of T cell differentiation. Nat Immunol 2: 102-107.
    • (2001) Nat Immunol , vol.2 , pp. 102-107
    • Luther, S.A.1    Cyster, J.G.2
  • 82
    • 0344736656 scopus 로고    scopus 로고
    • Abdelwahah SF, Cocchi F, Bagley KC, Kamin-Lewis R, Gallo RC, et al. (2003) HIV-1-suppressive factors are secreted by CD4+ T cells during primary immune responses. Proc Natl Acad Sci U 8 A 100: 15006-15010.
    • Abdelwahah SF, Cocchi F, Bagley KC, Kamin-Lewis R, Gallo RC, et al. (2003) HIV-1-suppressive factors are secreted by CD4+ T cells during primary immune responses. Proc Natl Acad Sci U 8 A 100: 15006-15010.
  • 83
    • 0037289727 scopus 로고    scopus 로고
    • MIP-1alpha and MIP-1beta differentially mediate mucosal and systemic adaptive immunity
    • Lillard JW Jr, Singh UP, Boyaka PN, Singh S, Taub DD, et al. (2003) MIP-1alpha and MIP-1beta differentially mediate mucosal and systemic adaptive immunity. Blood 101: 807-814.
    • (2003) Blood , vol.101 , pp. 807-814
    • Lillard Jr, J.W.1    Singh, U.P.2    Boyaka, P.N.3    Singh, S.4    Taub, D.D.5
  • 84
    • 2542428442 scopus 로고    scopus 로고
    • Chemokines in innate and adaptive host defense: Basic chemokinese grammar for immune cells
    • Rot A, von Andrian UH (2004) Chemokines in innate and adaptive host defense: basic chemokinese grammar for immune cells. Anon Rev Immumol 22:891-928.
    • (2004) Anon Rev Immumol , vol.22 , pp. 891-928
    • Rot, A.1    von Andrian, U.H.2
  • 86
    • 33645866471 scopus 로고    scopus 로고
    • Chemokines enhance immunity by guiding naive CD8+ T cells to sites of CD4+ T cell-dendritic cell interaction
    • Castellino F, Huang AY, Altan-Bonnet G, Stoll S, Scheinecker C, et al. (2006) Chemokines enhance immunity by guiding naive CD8+ T cells to sites of CD4+ T cell-dendritic cell interaction. Nature 440: 890-895.
    • (2006) Nature , vol.440 , pp. 890-895
    • Castellino, F.1    Huang, A.Y.2    Altan-Bonnet, G.3    Stoll, S.4    Scheinecker, C.5
  • 87
    • 33748866330 scopus 로고    scopus 로고
    • Surface-bound chemokines capture and prime T cells for synapse formation
    • Friedman RS, Jacobelli J, Krummel MF (2006) Surface-bound chemokines capture and prime T cells for synapse formation. Nat Immunol 7: 1101-1108.
    • (2006) Nat Immunol , vol.7 , pp. 1101-1108
    • Friedman, R.S.1    Jacobelli, J.2    Krummel, M.F.3
  • 88
    • 0037180502 scopus 로고    scopus 로고
    • Cell surface CCR5 density determines the postentry efficiency of R5 HIV-1 infection
    • Lin YL, Mettling C, Portales P, Reynes J, Clot J, et al. (2002) Cell surface CCR5 density determines the postentry efficiency of R5 HIV-1 infection. Proc Natl Acad Sci U S A 99: 15590-15595.
    • (2002) Proc Natl Acad Sci U S A , vol.99 , pp. 15590-15595
    • Lin, Y.L.1    Mettling, C.2    Portales, P.3    Reynes, J.4    Clot, J.5
  • 89
    • 17444376444 scopus 로고    scopus 로고
    • Macrophage inflammatory protein lalpha inhibits postentry steps of human immunodeficiency virus type 1 infection via suppression of intracellular cyclic AMP
    • Amella CA, Sherry B, Shepp DH, Schmidtmayerova H (2005) Macrophage inflammatory protein lalpha inhibits postentry steps of human immunodeficiency virus type 1 infection via suppression of intracellular cyclic AMP. J Virol 79: 5625-5631.
    • (2005) J Virol , vol.79 , pp. 5625-5631
    • Amella, C.A.1    Sherry, B.2    Shepp, D.H.3    Schmidtmayerova, H.4
  • 90
    • 30744447910 scopus 로고    scopus 로고
    • CCL5-CCR5 interaction provides antiapoptotic signals for macrophage survival during viral infection
    • Tyner JW, Uchida O, Kajiwara N, Kim EY, Patel AC, et al. (2005) CCL5-CCR5 interaction provides antiapoptotic signals for macrophage survival during viral infection. Nat Med 11: 1180-1187.
    • (2005) Nat Med , vol.11 , pp. 1180-1187
    • Tyner, J.W.1    Uchida, O.2    Kajiwara, N.3    Kim, E.Y.4    Patel, A.C.5
  • 91
    • 33749079234 scopus 로고    scopus 로고
    • Predictive value of plasma HIV RNA level on rate of CD4 T-cell decline in untreated HIV infection
    • Rodriguez B, Sethi AK, Cheruvu VK, Mackay W, Bosch RJ, et al. (2006) Predictive value of plasma HIV RNA level on rate of CD4 T-cell decline in untreated HIV infection. Jama 296: 1498-1506.
    • (2006) Jama , vol.296 , pp. 1498-1506
    • Rodriguez, B.1    Sethi, A.K.2    Cheruvu, V.K.3    Mackay, W.4    Bosch, R.J.5
  • 92
    • 52349099229 scopus 로고    scopus 로고
    • Mayer H, Van der Ryst E, Saag M, Clotet B, Fatkenheuer G, et al. (2006) Safety and efficacy of maraviroc (MVC), a novel CCR5 antagonist, when used in combination with optimized background therapy (OBT) for the treatment of antiretroviral-experienced subjects infected with dual/ mixed-tropic HIV-1: 24-week results of a phase 2b exploratory trial. In: Programs and abstracts of the XVI International AIDS Conference. Abstract THLB0215. 2006.
    • Mayer H, Van der Ryst E, Saag M, Clotet B, Fatkenheuer G, et al. (2006) Safety and efficacy of maraviroc (MVC), a novel CCR5 antagonist, when used in combination with optimized background therapy (OBT) for the treatment of antiretroviral-experienced subjects infected with dual/ mixed-tropic HIV-1: 24-week results of a phase 2b exploratory trial. In: Programs and abstracts of the XVI International AIDS Conference. Abstract THLB0215. 2006.
  • 93
    • 40549092975 scopus 로고    scopus 로고
    • Safety, pharmacokinetics, and antiviral activity of HGS004, a novel Fully human IgG4 monoclonal antibody against CCR5, in HIV-1-infected patients
    • Lalezari J, Yadavalli GK, Para M, Richmond G, Dejesus E, et al. (2008) Safety, pharmacokinetics, and antiviral activity of HGS004, a novel Fully human IgG4 monoclonal antibody against CCR5, in HIV-1-infected patients. J Infect Dis 197: 721-727.
    • (2008) J Infect Dis , vol.197 , pp. 721-727
    • Lalezari, J.1    Yadavalli, G.K.2    Para, M.3    Richmond, G.4    Dejesus, E.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.