메뉴 건너뛰기




Volumn 14, Issue 1, 2015, Pages 1-6

Short-term effects of a combined nutraceutical of insulin-sensitivity, lipid level and indexes of liver steatosis: A double-blind, randomized, cross-over clinical trial

Author keywords

Berberine; Chlorogenic acid; Insulin sensitivity; Lipoproteins; Liver steatosis; Nutraceutical

Indexed keywords

ALPHA TOCOTRIENOL; ASPARTATE AMINOTRANSFERASE; BERBERINE; CHLOROGENIC ACID; HIGH DENSITY LIPOPROTEIN CHOLESTEROL; INSULIN; LIPID; LOW DENSITY LIPOPROTEIN CHOLESTEROL; NUTRACEUTICAL; PLACEBO; TRIACYLGLYCEROL;

EID: 84928573383     PISSN: None     EISSN: 14752891     Source Type: Journal    
DOI: 10.1186/s12937-015-0019-y     Document Type: Article
Times cited : (26)

References (28)
  • 1
    • 84906882822 scopus 로고    scopus 로고
    • Global, regional, and national prevalence of overweight and obesity in children and adults during 1980-2013: a systematic analysis for the Global Burden of Disease Study 2013
    • Ng M, Fleming T, Robinson M, Thomson B, Graetz N, Margono C, et al. Global, regional, and national prevalence of overweight and obesity in children and adults during 1980-2013: a systematic analysis for the Global Burden of Disease Study 2013. Lancet. 2014;384(9945):766-81.
    • (2014) Lancet , vol.384 , Issue.9945 , pp. 766-781
    • Ng, M.1    Fleming, T.2    Robinson, M.3    Thomson, B.4    Graetz, N.5    Margono, C.6
  • 2
    • 84902490263 scopus 로고    scopus 로고
    • The burden of overweight and obesity on long-term care and Medicaid financing
    • Yang Z, Zhang N. The burden of overweight and obesity on long-term care and Medicaid financing. Med Care. 2014;52(7):658-63.
    • (2014) Med Care , vol.52 , Issue.7 , pp. 658-663
    • Yang, Z.1    Zhang, N.2
  • 3
    • 84903778851 scopus 로고    scopus 로고
    • Prevention of chronic disease in the 21st century: elimination of the leading preventable causes of premature death and disability in the USA
    • Bauer UE, Briss PA, Goodman RA, Bowman BA. Prevention of chronic disease in the 21st century: elimination of the leading preventable causes of premature death and disability in the USA. Lancet. 2014;384(9937):45-52.
    • (2014) Lancet , vol.384 , Issue.9937 , pp. 45-52
    • Bauer, U.E.1    Briss, P.A.2    Goodman, R.A.3    Bowman, B.A.4
  • 4
    • 84900831239 scopus 로고    scopus 로고
    • Prevention of cardiovascular disease: updating the immensity of the challenge and the role of risk factors
    • Kones R, Rumana U. Prevention of cardiovascular disease: updating the immensity of the challenge and the role of risk factors. Hosp Pract. 2014;42(1):92-100.
    • (2014) Hosp Pract , vol.42 , Issue.1 , pp. 92-100
    • Kones, R.1    Rumana, U.2
  • 5
    • 84905311927 scopus 로고    scopus 로고
    • Managing overweight and obesity in adults to reduce cardiovascular disease risk
    • Ebbert JO, Elrashidi MY, Jensen MD. Managing overweight and obesity in adults to reduce cardiovascular disease risk. Curr Atheroscler Rep. 2014;16(10):445.
    • (2014) Curr Atheroscler Rep , vol.16 , Issue.10 , pp. 445
    • Ebbert, J.O.1    Elrashidi, M.Y.2    Jensen, M.D.3
  • 6
    • 84902142242 scopus 로고    scopus 로고
    • Pharmacotherapy for weight loss
    • Rueda-Clausen CF, Padwal RS. Pharmacotherapy for weight loss. BMJ. 2014;348:g3526.
    • (2014) BMJ , vol.348
    • Rueda-Clausen, C.F.1    Padwal, R.S.2
  • 7
    • 84878845892 scopus 로고    scopus 로고
    • Functional foods and nutraceuticals as therapeutic tools for the treatment of diet-related diseases
    • 1:CAS:528:DC%2BC3sXosFahtb8%3D
    • Magrone T, Perez de Heredia F, Jirillo E, Morabito G, Marcos A, Serafini M. Functional foods and nutraceuticals as therapeutic tools for the treatment of diet-related diseases. Can J Physiol Pharmacol. 2013;91(6):387-96.
    • (2013) Can J Physiol Pharmacol , vol.91 , Issue.6 , pp. 387-396
    • Magrone, T.1    Perez De Heredia, F.2    Jirillo, E.3    Morabito, G.4    Marcos, A.5    Serafini, M.6
  • 8
    • 80155184615 scopus 로고    scopus 로고
    • Pathogenic obesity and nutraceuticals
    • 1:CAS:528:DC%2BC3MXhtlKjtrfL
    • Conroy KP, Davidson IM, Warnock M. Pathogenic obesity and nutraceuticals. Proc Nutr Soc. 2011;70(4):426-38.
    • (2011) Proc Nutr Soc , vol.70 , Issue.4 , pp. 426-438
    • Conroy, K.P.1    Davidson, I.M.2    Warnock, M.3
  • 9
    • 84904764401 scopus 로고    scopus 로고
    • Nutraceuticals for metabolic syndrome management: from laboratory to benchside
    • 1:CAS:528:DC%2BC2cXhtFOgs7%2FI
    • Cicero AF, Tartagni E, Ertek S. Nutraceuticals for metabolic syndrome management: from laboratory to benchside. Curr Vasc Pharmacol. 2014;12(4):565-71.
    • (2014) Curr Vasc Pharmacol , vol.12 , Issue.4 , pp. 565-571
    • Cicero, A.F.1    Tartagni, E.2    Ertek, S.3
  • 10
    • 0017358973 scopus 로고
    • Enzymatic determination of total cholesterol with the Greiner Selective Analyzer (GSA II)
    • Klose S, Borner K. Enzymatic determination of total cholesterol with the Greiner Selective Analyzer (GSA II). J Clin Chem Clin Biochem. 1977;15:121-30.
    • (1977) J Clin Chem Clin Biochem , vol.15 , pp. 121-130
    • Klose, S.1    Borner, K.2
  • 11
    • 33745026603 scopus 로고
    • The distribution and chemical composition of ultracentrifugally separated lipoproteins in human serum
    • 1:CAS:528:DyaG28XitFyn
    • Havel RJ, Eder HA, Bragdon JH. The distribution and chemical composition of ultracentrifugally separated lipoproteins in human serum. J Clin Invest. 1955;34:1345-53.
    • (1955) J Clin Invest , vol.34 , pp. 1345-1353
    • Havel, R.J.1    Eder, H.A.2    Bragdon, J.H.3
  • 12
    • 0000773441 scopus 로고
    • Triglycerides determination after enzymatic hydrolysis
    • H. Bermeyer editor. 2nd English ed. New York: Academic Press
    • Wahlefeld AW. Triglycerides determination after enzymatic hydrolysis. In: Bermeyer H, editor. Methods of Enzymatic Analysis. 2nd English ed. New York: Academic Press; 1974. p. 18-31.
    • (1974) Methods of Enzymatic Analysis , pp. 18-31
    • Wahlefeld, A.W.1
  • 13
    • 0015348189 scopus 로고
    • Estimation of the concentration of low density lipoprotein cholesterol in plasma, without use of the preparative ultracentrifuge
    • 1:CAS:528:DyaE38Xkslagsbw%3D
    • Friedewald WT, Levy RI, Fredrickson DS. Estimation of the concentration of low density lipoprotein cholesterol in plasma, without use of the preparative ultracentrifuge. Clin Chem. 1972;18:499-502.
    • (1972) Clin Chem , vol.18 , pp. 499-502
    • Friedewald, W.T.1    Levy, R.I.2    Fredrickson, D.S.3
  • 14
    • 0021813187 scopus 로고
    • Homeostasis model assessment: insulin resistance and beta-cell function from fasting plasma glucose and insulin concentrations in man
    • 1:CAS:528:DyaL2MXlslKnu7k%3D
    • Matthews DR, Hosker JP, Rudenski AS, Naylor BA, Treacher DF, Turner RC. Homeostasis model assessment: insulin resistance and beta-cell function from fasting plasma glucose and insulin concentrations in man. Diabetologia. 1985;28:412-9.
    • (1985) Diabetologia , vol.28 , pp. 412-419
    • Matthews, D.R.1    Hosker, J.P.2    Rudenski, A.S.3    Naylor, B.A.4    Treacher, D.F.5    Turner, R.C.6
  • 15
    • 0037048946 scopus 로고    scopus 로고
    • Coffee consumption and risk of type 2 diabetes mellitus
    • van Dam RM, Feskens EJM. Coffee consumption and risk of type 2 diabetes mellitus. Lancet. 2002;360(9344):1477-8.
    • (2002) Lancet , vol.360 , Issue.9344 , pp. 1477-1478
    • Van Dam, R.M.1    Feskens, E.J.M.2
  • 16
    • 84875723971 scopus 로고    scopus 로고
    • Hepatic Steatosis Index and Lipid Accumulation Product as middle-term predictors of incident metabolic syndrome in a large population sample: data from the Brisighella Heart Study
    • Cicero AFG, D'Addato S, Reggi A, Marchesini Reggiani G, Borghi C, on behalf of the Brisighella Heart Study. Hepatic Steatosis Index and Lipid Accumulation Product as middle-term predictors of incident metabolic syndrome in a large population sample: data from the Brisighella Heart Study. Intern Emerg Med. 2013;8(3):265-7.
    • (2013) Intern Emerg Med , vol.8 , Issue.3 , pp. 265-267
    • Cicero, A.F.G.1    D'Addato, S.2    Reggi, A.3    Marchesini Reggiani, G.4    Borghi, C.5
  • 17
    • 13444293166 scopus 로고    scopus 로고
    • A chlorogenic acid-induced increase in GLP-1 production may mediate the impact of heavy coffee consumption on diabetes risk
    • 1:CAS:528:DC%2BD2MXhtVOlsbc%3D
    • McCarty MF. A chlorogenic acid-induced increase in GLP-1 production may mediate the impact of heavy coffee consumption on diabetes risk. Med Hypotheses. 2005;64(4):848-53.
    • (2005) Med Hypotheses , vol.64 , Issue.4 , pp. 848-853
    • McCarty, M.F.1
  • 18
    • 84937937489 scopus 로고    scopus 로고
    • Caffeic and chlorogenic acids inhibit key enzymes linked to type 2 diabetes (in vitro): a comparative study
    • Oboh G, Agunloye OM, Adefegha SA, Akinyemi AJ, Ademiluyi AO. Caffeic and chlorogenic acids inhibit key enzymes linked to type 2 diabetes (in vitro): a comparative study. J Basic Clin Physiol Pharmacol. 2015;26(2):165-70.
    • (2015) J Basic Clin Physiol Pharmacol , vol.26 , Issue.2 , pp. 165-170
    • Oboh, G.1    Agunloye, O.M.2    Adefegha, S.A.3    Akinyemi, A.J.4    Ademiluyi, A.O.5
  • 19
    • 67650787239 scopus 로고    scopus 로고
    • Modulating effects of chlorogenic acid on lipids and glucose metabolism and expression of hepatic peroxisome proliferator-activated receptor-alpha in golden hamsters fed on high fat diet
    • 1:CAS:528:DC%2BD1MXmt1Shu7k%3D
    • Li SY, Chang CQ, Ma FY, Yu CL. Modulating effects of chlorogenic acid on lipids and glucose metabolism and expression of hepatic peroxisome proliferator-activated receptor-alpha in golden hamsters fed on high fat diet. Biomed Environ Sci. 2009;22(2):122-9.
    • (2009) Biomed Environ Sci , vol.22 , Issue.2 , pp. 122-129
    • Li, S.Y.1    Chang, C.Q.2    Ma, F.Y.3    Yu, C.L.4
  • 20
    • 84875703218 scopus 로고    scopus 로고
    • Anti-diabetic and anti-lipidemic effects of chlorogenic acid are mediated by ampk activation
    • 1:CAS:528:DC%2BC3sXjslWrsr4%3D
    • Ong KW, Hsu A, Tan BK. Anti-diabetic and anti-lipidemic effects of chlorogenic acid are mediated by ampk activation. Biochem Pharmacol. 2013;85(9):1341-51.
    • (2013) Biochem Pharmacol , vol.85 , Issue.9 , pp. 1341-1351
    • Ong, K.W.1    Hsu, A.2    Tan, B.K.3
  • 21
    • 84897656243 scopus 로고    scopus 로고
    • Coffee and non-alcoholic fatty liver disease: brewing evidence for hepatoprotection?
    • Chen S, Teoh NC, Chitturi S, Farrell GC. Coffee and non-alcoholic fatty liver disease: brewing evidence for hepatoprotection? J Gastroenterol Hepatol. 2014;29(3):435-41.
    • (2014) J Gastroenterol Hepatol , vol.29 , Issue.3 , pp. 435-441
    • Chen, S.1    Teoh, N.C.2    Chitturi, S.3    Farrell, G.C.4
  • 22
    • 77649177283 scopus 로고    scopus 로고
    • Metabolic and cardiovascular effects of berberine: from preclinical evidences to clinical trial results
    • 1:CAS:528:DC%2BD1MXhtFygsLrM
    • Cicero AFG, Ertek S. Metabolic and cardiovascular effects of berberine: from preclinical evidences to clinical trial results. Clin Lipidol. 2009;4(5):553-63.
    • (2009) Clin Lipidol , vol.4 , Issue.5 , pp. 553-563
    • Cicero, A.F.G.1    Ertek, S.2
  • 23
    • 84863789913 scopus 로고    scopus 로고
    • Berberine on metabolic and cardiovascular risk factors: an analysis from preclinical evidences to clinical trials
    • 1:CAS:528:DC%2BC38XhtVemurvP
    • Derosa G, Maffioli P, Cicero AFG. Berberine on metabolic and cardiovascular risk factors: an analysis from preclinical evidences to clinical trials. Expert Opin Biol Ther. 2012;12(8):1113-24.
    • (2012) Expert Opin Biol Ther , vol.12 , Issue.8 , pp. 1113-1124
    • Derosa, G.1    Maffioli, P.2    Cicero, A.F.G.3
  • 24
    • 84887324829 scopus 로고    scopus 로고
    • Berberine induced improvement in Hepatic Steatosis Index in overweight dyslipidaemic patients treated with lipid-lowering nutraceuticals
    • 1:CAS:528:DC%2BC3sXht1ChtLvN
    • Cicero AFG, Derosa G, Maffioli P, Reggi A, Parini A, Rosticci M, et al. Berberine induced improvement in Hepatic Steatosis Index in overweight dyslipidaemic patients treated with lipid-lowering nutraceuticals. Curr Topics Nutr Res. 2013;11(1-2):41-6.
    • (2013) Curr Topics Nutr Res , vol.11 , Issue.1-2 , pp. 41-46
    • Cicero, A.F.G.1    Derosa, G.2    Maffioli, P.3    Reggi, A.4    Parini, A.5    Rosticci, M.6
  • 25
    • 84897522177 scopus 로고    scopus 로고
    • A comprehensive review on metabolic syndrome
    • Kaur J. A comprehensive review on metabolic syndrome. Cardiol Res Pract. 2014;2014:943162.
    • (2014) Cardiol Res Pract , vol.2014 , pp. 943162
    • Kaur, J.1
  • 26
    • 84908430615 scopus 로고    scopus 로고
    • Nonalcoholic fatty liver disease: A main driver of insulin resistance or a dangerous liaison?
    • 1:CAS:528:DC%2BC2cXhtlymu73M
    • Gruben N, Shiri-Sverdlov R, Koonen DP, Hofker MH. Nonalcoholic fatty liver disease: A main driver of insulin resistance or a dangerous liaison? Biochim Biophys Acta. 2014;1842(11):2329-43.
    • (2014) Biochim Biophys Acta , vol.1842 , Issue.11 , pp. 2329-2343
    • Gruben, N.1    Shiri-Sverdlov, R.2    Koonen, D.P.3    Hofker, M.H.4
  • 27
    • 75749098907 scopus 로고    scopus 로고
    • Long-term effect of a dietary education program on postmenopausal cardiovascular risk and metabolic syndrome: the Brisighella Heart Study
    • Cicero AF, Dormi A, D'Addato S, Gaddi AV, Borghi C. Long-term effect of a dietary education program on postmenopausal cardiovascular risk and metabolic syndrome: the Brisighella Heart Study. J Womens Health. 2010;19(1):133-7.
    • (2010) J Womens Health , vol.19 , Issue.1 , pp. 133-137
    • Cicero, A.F.1    Dormi, A.2    D'Addato, S.3    Gaddi, A.V.4    Borghi, C.5
  • 28
    • 84908867375 scopus 로고    scopus 로고
    • Role of diet and lifestyle changes in nonalcoholic fatty liver disease
    • 1:CAS:528:DC%2BC2cXhs1OmtL3J
    • Nseir W, Hellou E, Assy N. Role of diet and lifestyle changes in nonalcoholic fatty liver disease. World J Gastroenterol. 2014;20(28):9338-44.
    • (2014) World J Gastroenterol , vol.20 , Issue.28 , pp. 9338-9344
    • Nseir, W.1    Hellou, E.2    Assy, N.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.