Oropouche virus infection and pathogenesis are restricted by MAVs, IRF-3, IRF-7, and type I interferon signaling pathways in nonmyeloid cells

Journal of Virology

Volumn 89, Issue 9, 2015, Pages 4720-4737

  Proenca Modena, Jose Luiz ^a,b   Sesti Costa, Renata ^a,c   Pinto, Amelia K ^a   Richner, Justin M ^a   Lazear, Helen M ^a   Lucas, Tiffany ^a   Hyde, Jennifer L ^a   Diamond, Michael S ^a  

^a WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF CAMPINAS   (Brazil)

^c UNIVERSITY OF SÃO PAULO   (Brazil)

Author keywords

[No Author keywords available]

Indexed keywords

ALANINE AMINOTRANSFERASE; ALKALINE PHOSPHATASE; ASPARTATE AMINOTRANSFERASE; BETA INTERFERON; CELL PROTEIN; CREATINE KINASE; CREATININE; CXCL1 CHEMOKINE; GRANULOCYTE COLONY STIMULATING FACTOR; INTERFERON; INTERFERON RECEPTOR; INTERFERON REGULATORY FACTOR 3; INTERFERON REGULATORY FACTOR 7; INTERLEUKIN 12P40; INTERLEUKIN 1BETA; INTERLEUKIN 6; MACROPHAGE INFLAMMATORY PROTEIN 1ALPHA; MAVS PROTEIN; MONOCYTE CHEMOTACTIC PROTEIN 1; RANTES; RETINOIC ACID INDUCIBLE PROTEIN I; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG; IPS-1 PROTEIN, MOUSE; SIGNAL TRANSDUCING ADAPTOR PROTEIN;

ADULT; ALKALINE PHOSPHATASE BLOOD LEVEL; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BODY TEMPERATURE DISORDER; CELLS; CONTROLLED STUDY; CREATINE KINASE BLOOD LEVEL; CREATININE BLOOD LEVEL; CYTOKINE PRODUCTION; CYTOKINE STORM; DEATH; HUMAN; HUMAN CELL; IMMUNE RESPONSE; INNATE IMMUNITY; LETHARGY; LIVER INJURY; MOUSE; NEWBORN; NONHUMAN; NONMYELOID CELL; OROPOUCHE VIRUS INFECTION; ORTHOBUNYAVIRUS INFECTION; PRIORITY JOURNAL; PROTEIN FUNCTION; SIGNAL TRANSDUCTION; SURVIVAL TIME; UREA NITROGEN BLOOD LEVEL; VIRUS LOAD; VIRUS REPLICATION; WEIGHT REDUCTION; YOUNG ADULT; ANIMAL; BUNYAVIRUS INFECTION; C57BL MOUSE; CELL CULTURE; DISEASE MODEL; FIBROBLAST; IMMUNOLOGY; METABOLISM; ORTHOBUNYAVIRUS; PATHOLOGY; PHYSIOLOGY; SURVIVAL; VIROLOGY;

ANIMALIA; BUNYAVIRIDAE; HEXAPODA; LA CROSSE VIRUS; MUS; OROPOUCHE VIRUS; ORTHOBUNYAVIRUS;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; ANIMALS; BUNYAVIRIDAE INFECTIONS; CELLS, CULTURED; DISEASE MODELS, ANIMAL; FIBROBLASTS; INTERFERON REGULATORY FACTOR-3; INTERFERON REGULATORY FACTOR-7; INTERFERON TYPE I; MICE, INBRED C57BL; ORTHOBUNYAVIRUS; SIGNAL TRANSDUCTION; SURVIVAL ANALYSIS;

EID: 84928570469     PISSN: 0022538X     EISSN: 10985514     Source Type: Journal    
DOI: 10.1128/JVI.00077-15     Document Type: Article

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