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Volumn 34, Issue 2, 2015, Pages 134-142

Sex-driven differences in immunological responses: Challenges and opportunities for the immunotherapies of the third millennium

Author keywords

Cancer vaccines; Cancer testis atigens; Hormones; Immune response

Indexed keywords

CANCER TESTIS ANTIGEN; CANCER VACCINE; ESTROGEN; PROTEIN; ROPPORIN 1; TESTOSTERONE; UNCLASSIFIED DRUG; MEMBRANE PROTEIN; RHO GUANINE NUCLEOTIDE BINDING PROTEIN; ROPN1 PROTEIN, HUMAN; SEX HORMONE; TUMOR ANTIGEN;

EID: 84928549196     PISSN: 08830185     EISSN: 15635244     Source Type: Journal    
DOI: 10.3109/08830185.2015.1018417     Document Type: Review
Times cited : (41)

References (41)
  • 1
    • 78649903173 scopus 로고    scopus 로고
    • Sex bias in neuroscience and biomedical research
    • Beery AK, Zucker I. Sex bias in neuroscience and biomedical research. Neurosci Biobehav Rev 2011;35(3):565-572.
    • (2011) Neurosci Biobehav Rev , vol.35 , Issue.3 , pp. 565-572
    • Beery, A.K.1    Zucker, I.2
  • 2
    • 78649904536 scopus 로고    scopus 로고
    • Foreward: A historical overview of advocacy for research in sex-based biology
    • Marts SA, Keitt S. Foreward: A historical overview of advocacy for research in sex-based biology. Adv Mol Cell Biol 2004;34:v-xiii.
    • (2004) Adv Mol Cell Biol , vol.34 , pp. 5-13
    • Marts, S.A.1    Keitt, S.2
  • 3
    • 65349137639 scopus 로고    scopus 로고
    • Sex differences in pharmacokinetics and pharmacodynamics
    • Soldin OP, Mattison DR. Sex differences in pharmacokinetics and pharmacodynamics. Clin Pharmacokinet 2009;48(3):143-157.
    • (2009) Clin Pharmacokinet , vol.48 , Issue.3 , pp. 143-157
    • Soldin, O.P.1    Mattison, D.R.2
  • 4
    • 84892427565 scopus 로고    scopus 로고
    • Pharmacogenomics, pharmacokinetics and pharmacodynamics: Interaction with biological differences between men and women
    • Franconi F, Campesi I. Pharmacogenomics, pharmacokinetics and pharmacodynamics: Interaction with biological differences between men and women. Br J Pharmacol 2014;171(3):580-594.
    • (2014) Br J Pharmacol , vol.171 , Issue.3 , pp. 580-594
    • Franconi, F.1    Campesi, I.2
  • 5
    • 69249221632 scopus 로고    scopus 로고
    • Sex differences inmortality following acute coronary syndromes
    • Berger JS, Elliott L, Gallup D, et al. Sex differences inmortality following acute coronary syndromes. JAMA 2009;302(8):874-882.
    • (2009) JAMA , vol.302 , Issue.8 , pp. 874-882
    • Berger, J.S.1    Elliott, L.2    Gallup, D.3
  • 6
    • 79954597361 scopus 로고    scopus 로고
    • Gender-related variations in iron metabolism and liver diseases
    • Harrison-Findik DD. Gender-related variations in iron metabolism and liver diseases. World J hepatol 2010;2(8):302-310.
    • (2010) World J Hepatol , vol.2 , Issue.8 , pp. 302-310
    • Harrison-Findik, D.D.1
  • 7
    • 84857373685 scopus 로고    scopus 로고
    • Pattern of use ofDXA scans in men: A cross-sectional populationbased study
    • Frost M, Gudex C, Rubin KH, et al. Pattern of use ofDXA scans in men: A cross-sectional, populationbased study. Osteoporos Int 2012;23(1):183-191.
    • (2012) Osteoporos Int , vol.23 , Issue.1 , pp. 183-191
    • Frost, M.1    Gudex, C.2    Rubin, K.H.3
  • 8
    • 77956938954 scopus 로고    scopus 로고
    • Impact of age, sex, and comorbidity on cancer therapy and disease progression
    • Pal SK, Hurria A. Impact of age, sex, and comorbidity on cancer therapy and disease progression. J Clin Oncol 2010;28(26):4086-4093.
    • (2010) J Clin Oncol , vol.28 , Issue.26 , pp. 4086-4093
    • Pal, S.K.1    Hurria, A.2
  • 9
    • 0032971797 scopus 로고    scopus 로고
    • Estrogen enhances immunoglobulin production by human PBMCs
    • Kanda N, Tamaki K. Estrogen enhances immunoglobulin production by human PBMCs. J Allergy Clin Immunol 1999;103(2 Pt 1):282-288.
    • (1999) J Allergy Clin Immunol , vol.103 , Issue.2 , pp. 282-288
    • Kanda, N.1    Tamaki, K.2
  • 10
    • 0029827338 scopus 로고    scopus 로고
    • Testosterone inhibits immunoglobulin production by human peripheral blood mononuclear cells
    • Kanda N, Tsuchida T, Tamaki K. Testosterone inhibits immunoglobulin production by human peripheral blood mononuclear cells. Clin Exp Immunol 1996;106(2):410-415.
    • (1996) Clin Exp Immunol , vol.106 , Issue.2 , pp. 410-415
    • Kanda, N.1    Tsuchida, T.2    Tamaki, K.3
  • 11
    • 0028961264 scopus 로고
    • Protein tyrosine phosphatase 1C negatively regulates antigen receptor signaling in B lymphocytes and determines thresholds for negative selection
    • Cyster JG, Goodnow CC. Protein tyrosine phosphatase 1C negatively regulates antigen receptor signaling in B lymphocytes and determines thresholds for negative selection. Immunity 1995;2(1):13-24.
    • (1995) Immunity , vol.2 , Issue.1 , pp. 13-24
    • Cyster, J.G.1    Goodnow, C.C.2
  • 13
    • 0028105796 scopus 로고
    • Developmental regulation of the Bcl-2 protein and susceptibility to cell death in B lymphocytes
    • Merino R, Ding L, Veis DJ, et al. Developmental regulation of the Bcl-2 protein and susceptibility to cell death in B lymphocytes. EMBO J 1994;13(3):683-691.
    • (1994) EMBO J , vol.13 , Issue.3 , pp. 683-691
    • Merino, R.1    Ding, L.2    Veis, D.J.3
  • 14
    • 0032147065 scopus 로고    scopus 로고
    • CD22 negatively and positively regulates signal transduction through the B lymphocyte antigen receptor
    • Sato S, Tuscano JM, Inaoki M, Tedder TF. CD22 negatively and positively regulates signal transduction through the B lymphocyte antigen receptor. Semin Immunol 1998;10(4):287-297.
    • (1998) Semin Immunol , vol.10 , Issue.4 , pp. 287-297
    • Sato, S.1    Tuscano, J.M.2    Inaoki, M.3    Tedder, T.F.4
  • 15
    • 0023778073 scopus 로고
    • Regulation of theimmune response by sex hormones. i in vitro effects of estradiol and testosterone on pokeweed mitogen-induced human B cell differentiation
    • Sthoeger ZM, Chiorazzi N, LahitaRG. Regulation of theimmune response by sex hormones. I. In vitro effects of estradiol and testosterone on pokeweed mitogen-induced human B cell differentiation. J Immunol 1988;141(1):91-98.
    • (1988) J Immunol , vol.141 , Issue.1 , pp. 91-98
    • Sthoeger, Z.M.1    Chiorazzi, N.2    Lahita, R.G.3
  • 16
    • 84908457723 scopus 로고    scopus 로고
    • Sex disparities in melanoma outcomes:The role of biology
    • Nostrati A, Wei ML. Sex disparities in melanoma outcomes:The role of biology. Arch Biochem Biophys 2014;563:42-50.
    • (2014) Arch Biochem Biophys , vol.563 , pp. 42-50
    • Nostrati, A.1    Wei, M.L.2
  • 17
    • 0037378670 scopus 로고    scopus 로고
    • Beneficial effects of the anti-oestrogen tamoxifen on systemic lupus erythematosus of (NZBxNZW)F1 femalemice are associated with specific reduction of IgG3 autoantibodies
    • Sthoeger ZM, ZingerH, Mozes E. Beneficial effects of the anti-oestrogen tamoxifen on systemic lupus erythematosus of (NZBxNZW)F1 femalemice are associated with specific reduction of IgG3 autoantibodies. Ann Rheum Dis 2003;62(4):341-346.
    • (2003) Ann Rheum Dis , vol.62 , Issue.4 , pp. 341-346
    • Sthoeger, Z.M.1    Zinger, H.2    Mozes, E.3
  • 18
    • 50249179849 scopus 로고    scopus 로고
    • The X-files in immunity: Sex-based differences predispose immune responses
    • Fish EN.The X-files in immunity: Sex-based differences predispose immune responses. Nat Rev Immunol 2008;8(9):737-744.
    • (2008) Nat Rev Immunol , vol.8 , Issue.9 , pp. 737-744
    • Fish, E.N.1
  • 19
    • 0028868743 scopus 로고
    • Genetic control of the CD4/CD8 T-cell ratio in humans
    • Amadori A, Zamarchi R, De Silvestro G, et al. Genetic control of the CD4/CD8 T-cell ratio in humans. NatMed 1995;1(12):1279-1283.
    • (1995) Nat Med , vol.1 , Issue.12 , pp. 1279-1283
    • Amadori, A.1    Zamarchi, R.2    De Silvestro, G.3
  • 20
    • 33846899223 scopus 로고    scopus 로고
    • Expansion of CD4+CD25+and FOXP3 +regulatory T cells during the follicular phase of the menstrual cycle: Implications for human reproduction
    • Arruvito L, Sanz M, Banham AH, Fainboim L. Expansion of CD4+CD25+and FOXP3 +regulatory T cells during the follicular phase of the menstrual cycle: Implications for human reproduction. J Immunol 2007;178(4):2572-2578.
    • (2007) J Immunol , vol.178 , Issue.4 , pp. 2572-2578
    • Arruvito, L.1    Sanz, M.2    Banham, A.H.3    Fainboim, L.4
  • 21
    • 39449126502 scopus 로고    scopus 로고
    • The Foxp3+ regulatory T cell: A jack of all trades, master of regulation
    • Tang Q, Bluestone JA. The Foxp3+ regulatory T cell: A jack of all trades, master of regulation. Nat Immunol 2008;9(3):239-244.
    • (2008) Nat Immunol , vol.9 , Issue.3 , pp. 239-244
    • Tang, Q.1    Bluestone, J.A.2
  • 22
    • 33747605602 scopus 로고    scopus 로고
    • Early rheumatoid arthritis is associated with a deficit in the CD4+CD25high regulatory T cell population in peripheral blood
    • Lawson CA, Brown AK, Bejarano V, et al. Early rheumatoid arthritis is associated with a deficit in the CD4+CD25high regulatory T cell population in peripheral blood. Rheumatology (Oxford) 2006;45(10):1210-1217.
    • (2006) Rheumatology (Oxford) , vol.45 , Issue.10 , pp. 1210-1217
    • Lawson, C.A.1    Brown, A.K.2    Bejarano, V.3
  • 23
    • 18644385642 scopus 로고    scopus 로고
    • Estrogen regulates CCR gene expression and function in T lymphocytes
    • Mo R, Chen J, Grolleau-Julius A, et al. Estrogen regulates CCR gene expression and function in T lymphocytes. J Immunol 2005;174(10):6023-6029.
    • (2005) J Immunol , vol.174 , Issue.10 , pp. 6023-6029
    • Mo, R.1    Chen, J.2    Grolleau-Julius, A.3
  • 24
    • 34548321649 scopus 로고    scopus 로고
    • Estrogen and CD4+ T cells
    • Pernis AB. Estrogen and CD4+ T cells. Curr Opin Rheumatol 2007;19(5):414-420.
    • (2007) Curr Opin Rheumatol , vol.19 , Issue.5 , pp. 414-420
    • Pernis, A.B.1
  • 25
    • 35649000846 scopus 로고    scopus 로고
    • 17beta-Estradiol utilizes the estrogen receptor to regulate CD16 expression in monocytes
    • Kramer PR, Winger V, Kramer SF. 17beta-Estradiol utilizes the estrogen receptor to regulate CD16 expression in monocytes.Mol Cell Endocrinol 2007;279(1-2):16-25.
    • (2007) Mol Cell Endocrinol , vol.279 , Issue.1-2 , pp. 16-25
    • Kramer, P.R.1    Winger, V.2    Kramer, S.F.3
  • 26
    • 2642566162 scopus 로고    scopus 로고
    • 17 beta-estradiol regulates cytokine release through modulation of CD16 expression in monocytes and monocyte-derived macrophages
    • Kramer PR, Kramer SF, Guan G. 17 beta-estradiol regulates cytokine release through modulation of CD16 expression in monocytes and monocyte-derived macrophages. Arthritis Rheum 2004;50(6):1967-1975.
    • (2004) Arthritis Rheum , vol.50 , Issue.6 , pp. 1967-1975
    • Kramer, P.R.1    Kramer, S.F.2    Guan, G.3
  • 27
    • 21244442986 scopus 로고    scopus 로고
    • Sex hormones and the immune response in humans
    • Bouman A, Heineman MJ, Faas MM. Sex hormones and the immune response in humans. Hum Reprod Update 2005;11(4):411-423.
    • (2005) Hum Reprod Update , vol.11 , Issue.4 , pp. 411-423
    • Bouman, A.1    Heineman, M.J.2    Faas, M.M.3
  • 28
    • 0344771013 scopus 로고    scopus 로고
    • Estrogen stimulates neuronal nitric oxide synthase protein expression in human neutrophils
    • Garcia-Duran M, de Frutos T, Diaz-Recasens J, et al. Estrogen stimulates neuronal nitric oxide synthase protein expression in human neutrophils. Circ Res 1999;85(11):1020-1026.
    • (1999) Circ Res , vol.85 , Issue.11 , pp. 1020-1026
    • Garcia-Duran, M.1    De Frutos, T.2    Diaz-Recasens, J.3
  • 29
    • 0026544385 scopus 로고
    • Effects of sex hormones on chemotaxis of human peripheral polymorphonuclear leukocytes and monocytes
    • Miyagi M, Aoyama H, Morishita M, Iwamoto Y. Effects of sex hormones on chemotaxis of human peripheral polymorphonuclear leukocytes and monocytes. J Periodontol 1992;63(1):28-32.
    • (1992) J Periodontol , vol.63 , Issue.1 , pp. 28-32
    • Miyagi, M.1    Aoyama, H.2    Morishita, M.3    Iwamoto, Y.4
  • 30
    • 35848967602 scopus 로고    scopus 로고
    • Modulation of 17beta-estradiol on the number and cytotoxicity of NK cells in vivo related to MCM and activating receptors
    • Hao S, Zhao J, Zhou J, et al. Modulation of 17beta-estradiol on the number and cytotoxicity of NK cells in vivo related to MCM and activating receptors. Int Immunopharm 2007;7(13): 1765-75.
    • (2007) Int Immunopharm , vol.7 , Issue.13 , pp. 1765-1775
    • Hao, S.1    Zhao, J.2    Zhou, J.3
  • 31
    • 84878065445 scopus 로고    scopus 로고
    • Estradiol promotes functional responses in inflammatory and steady-state dendritic cells through differential requirement for activation function-1 of estrogen receptor alpha
    • Seillet C, Rouquie N, Foulon E, et al. Estradiol promotes functional responses in inflammatory and steady-state dendritic cells through differential requirement for activation function-1 of estrogen receptor alpha. J Immunol 2013;190(11):5459-5470.
    • (2013) J Immunol , vol.190 , Issue.11 , pp. 5459-5470
    • Seillet, C.1    Rouquie, N.2    Foulon, E.3
  • 32
    • 75649112342 scopus 로고    scopus 로고
    • Estrogen receptor signaling promotes dendritic cell differentiation by increasing expression of the transcription factor IRF4
    • Carreras E, Turner S, Frank MB, et al. Estrogen receptor signaling promotes dendritic cell differentiation by increasing expression of the transcription factor IRF4. Blood 2010;115(2):238-246.
    • (2010) Blood , vol.115 , Issue.2 , pp. 238-246
    • Carreras, E.1    Turner, S.2    Frank, M.B.3
  • 33
    • 40749092841 scopus 로고    scopus 로고
    • 17beta-estradiol alters the activity of conventional and IFN-producing killer dendritic cells
    • Siracusa MC, Overstreet MG, Housseau F, et al. 17beta-estradiol alters the activity of conventional and IFN-producing killer dendritic cells. J Immunol 2008;180(3):1423-1431.
    • (2008) J Immunol , vol.180 , Issue.3 , pp. 1423-1431
    • Siracusa, M.C.1    Overstreet, M.G.2    Housseau, F.3
  • 34
    • 0025009910 scopus 로고
    • A novel X-linked combined immunodeficiency disease
    • Brooks EG, Schmalstieg FC, Wirt DP, et al. A novel X-linked combined immunodeficiency disease. J Clin Invest 1990;86(5):1623-1631.
    • (1990) J Clin Invest , vol.86 , Issue.5 , pp. 1623-1631
    • Brooks, E.G.1    Schmalstieg, F.C.2    Wirt, D.P.3
  • 36
    • 84904112296 scopus 로고    scopus 로고
    • Immunotherapy in the treatment of non-small cell lung cancer
    • Sundar R, Soong R, Cho BC, et al. Immunotherapy in the treatment of non-small cell lung cancer. Lung Cancer (Amsterdam) 2014;85(2):101-109.
    • (2014) Lung Cancer (Amsterdam) , vol.85 , Issue.2 , pp. 101-109
    • Sundar, R.1    Soong, R.2    Cho, B.C.3
  • 37
    • 84908354848 scopus 로고    scopus 로고
    • Anti-programmed-death-receptor-1 treatment with pembrolizumab in ipilimumab-refractory advanced melanoma: A randomised dose-comparison cohort of a phase 1 trial
    • Robert C, Ribas A, Wolchok JD, et al. Anti-programmed-death-receptor-1 treatment with pembrolizumab in ipilimumab-refractory advanced melanoma: A randomised dose-comparison cohort of a phase 1 trial. Lancet 2014;384(9948):1109-1117.
    • (2014) Lancet , vol.384 , Issue.9948 , pp. 1109-1117
    • Robert, C.1    Ribas, A.2    Wolchok, J.D.3
  • 38
    • 78049406865 scopus 로고    scopus 로고
    • B7-H1-dependent sex-related differences in tumor immunity and immunotherapy responses
    • Lin PY, Sun L, Thibodeaux SR, et al. B7-H1-dependent sex-related differences in tumor immunity and immunotherapy responses. J Immunol 2010;185(5):2747-2753.
    • (2010) J Immunol , vol.185 , Issue.5 , pp. 2747-2753
    • Lin, P.Y.1    Sun, L.2    Thibodeaux, S.R.3
  • 39
    • 77649184901 scopus 로고    scopus 로고
    • Clinical significance of cancer/testis antigens expression in patients with non-small cell lung cancer
    • Shigematsu Y, Hanagiri T, Shiota H, et al. Clinical significance of cancer/testis antigens expression in patients with non-small cell lung cancer. Lung cancer (Amsterdam) 2010;68(1):105-110.
    • (2010) Lung Cancer (Amsterdam) , vol.68 , Issue.1 , pp. 105-110
    • Shigematsu, Y.1    Hanagiri, T.2    Shiota, H.3
  • 40
    • 28144457350 scopus 로고    scopus 로고
    • Cancer-testis genes are coordinately expressed and aremarkers of poor outcome in non-small cell lung cancer
    • GureAO, ChuaR, WilliamsonB, et al.Cancer-testis genes are coordinately expressed and aremarkers of poor outcome in non-small cell lung cancer. Clin Cancer Res 2005;11(22):8055-8062.
    • (2005) Clin Cancer Res , vol.11 , Issue.22 , pp. 8055-8062
    • Gure, A.O.1    Chua, R.2    Williamson, B.3
  • 41
    • 79959805554 scopus 로고    scopus 로고
    • Cancer testis antigen, ropporin, is a potential target for multiplemyeloma immunotherapy
    • International
    • Chiriva-InternatiM, Mirandola L, Yu Y, et al. Cancer testis antigen, ropporin, is a potential target for multiplemyeloma immunotherapy. J Immunother 2011;34(6):490-499. International
    • (2011) J Immunother , vol.34 , Issue.6 , pp. 490-499
    • Chiriva-Internati, M.1    Mirandola, L.2    Yu, Y.3


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