Modulation of 17β-estradiol on the number and cytotoxicity of NK cells in vivo related to MCM and activating receptors

International Immunopharmacology

Volumn 7, Issue 13, 2007, Pages 1765-1775

  Hao, Sha ^a   Zhao, Junli ^a   Zhou, Jianjun ^b   Zhao, Shuli ^a   Hu, Yali ^b   Hou, Yayi ^a  

^a NANJING UNIVERSITY   (China)

^b MEDICAL SCHOOL OF NANJING UNIVERSITY   (China)

Author keywords

17 beta estradiol; Cytotoxicity; Natural killer cell; NK cell receptor; Ovariectomy

Indexed keywords

CD69 ANTIGEN; DNA; ESTRADIOL; GAMMA INTERFERON; GRANZYME B; MINICHROMOSOME MAINTENANCE PROTEIN; CD244 PROTEIN, MOUSE; CELL CYCLE PROTEIN; DNA BINDING PROTEIN; IMMUNOGLOBULIN RECEPTOR; LEUKOCYTE ANTIGEN; MCM7 PROTEIN, MOUSE; MEMBRANE PROTEIN; NATURAL KILLER CELL ACTIVATING RECEPTORS; NUCLEAR PROTEIN; T LYMPHOCYTE ANTIGEN; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL PROLIFERATION; CONTROLLED STUDY; CYTOTOXICITY; DNA REPLICATION; DOWN REGULATION; FEMALE; IN VIVO STUDY; LYMPHOCYTE COUNT; MOUSE; NATURAL KILLER CELL; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN EXPRESSION; SPLEEN CELL; UPREGULATION; ANIMAL; BIOSYNTHESIS; BLOOD; C57BL MOUSE; CELL LINE; CYTOLOGY; DNA MICROARRAY; DRUG EFFECT; GENE EXPRESSION REGULATION; GENETICS; IMMUNOLOGY; METABOLISM; SPLEEN; UTERUS;

ANIMALS; ANTIGENS, CD; ANTIGENS, DIFFERENTIATION, T-LYMPHOCYTE; CELL CYCLE PROTEINS; CELL LINE; CYTOTOXICITY, IMMUNOLOGIC; DNA-BINDING PROTEINS; ESTRADIOL; FEMALE; GENE EXPRESSION REGULATION; INTERFERON TYPE II; KILLER CELLS, NATURAL; MEMBRANE GLYCOPROTEINS; MICE; MICE, INBRED C57BL; NUCLEAR PROTEINS; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; RECEPTORS, IMMUNOLOGIC; SPLEEN; UTERUS;

EID: 35848967602     PISSN: 15675769     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.intimp.2007.09.017     Document Type: Article

References (29)

1. Hoffman-Goetz L. Effect of estradiol and exercise on lymphocyte proliferation responses in female mice. Physiol Behav 68 (1999) 169-174
2. Karpuzoglu-Sahin E., Zhi-Jun Y., Lengi A.N., et al. Effects of long-term estrogen treatment on IFN-γ, IL-2 and IL-4 gene expression and protein synthesis in spleen and thymus of normal C57BL/6 mice. Cytokine 14 4 (2001) 208-217
3. Ahmed S.A. The immune system as a potential target for environmental estrogens (endocrine disrupters): a new emerging field. Toxicology 150 (2000) 191-206
4. Nakaya M., Tachibana H., and Yamada K. Effect of estrogens on the interferon-g producing cell population of mouse splenocytes. Biosci Biotechnol Biochem 70 1 (2006) 47-53
5. Curran E.M., Berghaus L.J., Vernetti N.J., et al. Natural killer cells express estrogen receptor-α and estrogen receptor-β and can respond to estrogen via a non-estrogen receptor-α-mediated pathway. Cell Immunol 214 (2001) 12-20
6. Sorachi K., Kumagai S., Sugita M., et al. Enhancing effect of 17β-estradiol on human NK cell activity. Immunol Lett 36 (1993) 31-35
7. Dosiou C., and Giudice L.C. Natural killer cells in pregnancy and recurrent pregnancy loss: endocrine and immunologic perspectives. Endocr Rev 26 1 (2005) 44-62
8. Souza S.S., Castro F.A., Mendonc H.C., et al. Influence of menstrual cycle on NK activity. J Reprod Immunol 50 (2001) 151-159
9. Baral E., Nagy E., and Berczi I. Modulation of natural killer cell mediated cytotoxicity by tamoxifen and estradiol. Cancer 75 (1995) 591-599
10. Sulke A.N., Jones D.B., and Wood P.J. Hormonal modulation of human natural killer cell activity in vitro. J Reprod Immunol 7 2 (1985) 105-110
11. Human J.U. NK cell activity is not inhibited by pregnancy and cord serum factors and female steroid hormones in vitro. J Reprod Immunol 7 (1985) 111-120
12. Friberg D.D., Bryant J.L., and Whiteside T.L. Measurements of natural killer (NK) activity and NK-cell quantification. Methods: A Companion to Methods in Enzymology 9 (1996) 316-326
13. Stahl M.M., and Cederbrant K. A flow-cytometric NK-cytotoxicity assay adapted for use in rat repeated dose toxicity studies. Toxicology 193 (2003) 269-279
14. Takeda K., Cretney E., Hayakawa Y., et al. TRAIL identifies immature natural killer cells in newborn mice and adult mouse liver. Blood (2005) 2082-2089
15. Yovel G., Shakhar K., and Eliyahu S.B. The effects of sex, menstrual cycle, and oral contraceptives on the number and activity of natural killer cells. Gynecol Oncol 81 (2000) 1254-1262
16. Maiorano D., Lutzmann M., and Mechali M. MCM proteins and DNA replication. Curr Opin Cell Biol 18 (2006) 130-136
17. Ricke R.M., and Bielinsky A.K. Mcm10 regulates the stability and chromatin association of dna polymerase-a. Mol Cell 16 (2004) 173-185
18. Pan H.Y., Deng Y., and Pollard J.W. Progesterone blocks estrogen-induced DNA synthesis through the inhibition of replication licensing. PNAS 103 38 (2006) 14021-14026
19. Beagley K.W., and Gockel C.M. Regulation of innate and adaptive immunity by the female sex hormones oestradiol and progesterone. FEMS Immunol Med Microbiol 38 (2003) 13-22
20. Yokoyama W.M., and Plougastel B.F.M. Immune functions encoded by the natural killer gene complex. Nat Rev, Immunol 3 (2003) 304-316
21. Raulet D.H. Interplay of natural killer cells and their receptors with the adaptive immune response. Nat Immunol 5 10 (2004) 996-1002
22. Ashkar A.A., and Croy B.A. Interferon-γ contributes to the normalcy of murine pregnancy. Biol Reprod 61 (1999) 493-502
23. Nakaya M., Yamasaki M., Miyazaki Y., et al. Estrogenic compounds suppressed interferon-gamma production in mouse splenocytes through direct cell-cell interaction in vitro. Cell Dev Biol Anim 39 8-9 (2003) 383-387
24. Zhang C., Zhang J., Tian Z.G., et al. Opposing effect of IFNg and IFNa on expression of NKG2 receptors: negative regulation of IFNg on NK cells. Int. Immunopharmacol. 5 (2005) 1057-1106
25. Bosea A., and Baral R. IFNα2b stimulated release of IFNγ differentially regulates T cell and NK cell mediated tumor cell cytotoxicity. Immunol Lett 108 1 (2007) 68-77
26. Kagi D., Ledermann B., Burki K., et al. Cytotoxicity mediated by T cells and natural killer cells is greatly impaired in perforin deficient mice. Nature 369 (1994) 31-37
27. Eriksson M., Leitz G., Fallman E., et al. Inhibitory receptors alter natural killer cell interactions with target cells yet allow simultaneous killing of susceptible targets. J Exp Med 190 (1999) 1005-1012
28. Screpanti V., Wallin R.P., Ljunggren H.G., and Grandien A. A central role for death receptor-mediated apoptosis in the rejection of tumors by NK cells. J Immunol 167 (2001) 2068
29. Li A., He M., Wang H., et al. All-trans retinoic acid negatively regulates cytotoxic activities of nature killer cell line 92. Biochem Biophys Res Commun 352 (2007) 42-47