MNADK, a long-awaited human mitochondrion-localized NAD kinase

Journal of Cellular Physiology

Volumn 230, Issue 8, 2015, Pages 1697-1701

  Zhang, Ren ^a  

^a WAYNE STATE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

MITOCHONDRIAL NICOTINAMIDE ADENINE DINUCLEOTIDE; NICOTINAMIDE ADENINE DINUCLEOTIDE KINASE; UNCLASSIFIED DRUG; MITOCHONDRIAL PROTEIN; NADK2 PROTEIN, HUMAN; PHOSPHOTRANSFERASE;

ARABIDOPSIS THALIANA; CHLOROPLAST; CYTOSOL; ENZYME LOCALIZATION; FAILURE TO THRIVE; FRAMESHIFT MUTATION; HUMAN; MICROCEPHALY; MITOCHONDRIAL MEMBRANE; MITOCHONDRION; MUSCLE HYPOTONIA; NONHUMAN; NONSENSE MUTATION; NUCLEAR MAGNETIC RESONANCE IMAGING; OXIDATIVE STRESS; OXYGEN CONSUMPTION; PEROXISOME; PRIORITY JOURNAL; REVIEW; SACCHAROMYCES CEREVISIAE; STOP CODON; ANIMAL; ENZYMOLOGY; MOUSE; PHYSIOLOGY;

EUKARYOTA; MAMMALIA;

ANIMALS; HUMANS; MICE; MITOCHONDRIA; MITOCHONDRIAL PROTEINS; PHOSPHOTRANSFERASES (ALCOHOL GROUP ACCEPTOR);

EID: 84928399000     PISSN: 00219541     EISSN: 10974652     Source Type: Journal    
DOI: 10.1002/jcp.24926     Document Type: Review

References (39)

1. Agledal L, Niere M, Ziegler M. 2010. The phosphate makes a difference: Cellular functions of NADP. Redox Rep 15: 2-10.
2. Balaban RS, Nemoto S, Finkel T. 2005. Mitochondria, oxidants, and aging. Cell 120: 483-495.
3. Berrin JG, Pierrugues O, Brutesco C, Alonso B, Montillet JL, Roby D, Kazmaier M. 2005. Stress induces the expression of AtNADK-1, a gene encoding a NAD(H) kinase in Arabidopsis thaliana. Mol Genet Genomics 273: 10-19.
4. Bieganowski P, Seidle HF, Wojcik M, Brenner C. 2006. Synthetic lethal and biochemical analyses of NAD and NADH kinases in Saccharomyces cerevisiae establish separation of cellular functions. J Biol Chem 281: 22439-22445.
5. Chai MF, Chen QJ, An R, Chen YM, Chen J, Wang XC. 2005. NADK2, an Arabidopsis chloroplastic NAD kinase, plays a vital role in both chlorophyll synthesis and chloroplast protection. Plant Mol Biol 59: 553-564.
6. Colombini M. 1979. A candidate for the permeability pathway of the outer mitochondrial membrane. Nature 279: 643-645.
7. Dereeper A, Guignon V, Blanc G, Audic S, Buffet S, Chevenet F, Dufayard JF, Guindon S, Lefort V, Lescot M, Claverie JM, Gascuel O. 2008. Phylogeny.fr: Robust phylogenetic analysis for the non-specialist. Nucleic Acids Res 36:W465-W469.
8. Dieter P, Marme D. 1984. A Ca2 +, Calmodulin-dependent NAD kinase from corn is located in the outer mitochondrial membrane. J Biol Chem 259: 184-189.
9. Ghaemmaghami S, Huh WK, Bower K, Howson RW, Belle A, Dephoure N, O'Shea EK, Weissman JS. 2003. Global analysis of protein expression in yeast. Nature 425: 737-741.
10. Griendling KK, Sorescu D, Ushio-Fukai M. 2000. NAD(P)H oxidase: Role in cardiovascular biology and disease. Circ Res 86: 494-501.
11. Guse AH, Lee HC. 2008. NAADP: A universal Ca2+ trigger. Sci Signal 1: re10.
12. Houten SM, Denis S, Te Brinke H, Jongejan A, van Kampen AH, Bradley EJ, Baas F, Hennekam RC, Millington DS, Young SP, Frazier DM, Gucsavas-Calikoglu M, Wanders RJ. 2014. Mitochondrial NADP(H) deficiency due to a mutation in NADK2 causes dienoyl-CoA reductase deficiency with hyperlysinemia. Hum Mol Genet 23: 5009-5016.
13. Jeon SM, Chandel NS, Hay N. 2012. AMPK regulates NADPH homeostasis to promote tumour cell survival during energy stress. Nature 485: 661-665.
14. Kawai S, Murata K. 2008. Structure and function of NAD kinase and NADP phosphatase: Key enzymes that regulate the intracellular balance of NAD(H) and NADP(H). Biosci Biotechnol Biochem 72: 919-930.
15. Kawai S, Suzuki S, Mori S, Murata K. 2001. Molecular cloning and identification of UTR1 of a yeast Saccharomyces cerevisiae as a gene encoding an NAD kinase. FEMS Microbiol Lett 200: 181-184.
16. Krems B, Charizanis C, Entian KD. 1995. Mutants of Saccharomyces cerevisiae sensitive to oxidative and osmotic stress. Curr Genet 27: 427-434.
17. Lerner F, Niere M, Ludwig A, Ziegler M. 2001. Structural and functional characterization of human NAD kinase. Biochem Biophys Res Commun 288: 69-74.
18. Li Y, Huang TT, Carlson EJ, Melov S, Ursell PC, Olson JL, Noble LJ, Yoshimura MP, Berger C, Chan PH, Wallace DC, Epstein CJ. 1995. Dilated cardiomyopathy and neonatal lethality in mutant mice lacking manganese superoxide dismutase. Nat Genet 11: 376-381.
19. Luo J, Nikolaev AY, Imai S, Chen D, Su F, Shiloh A, Guarente L, Gu W. 2001. Negative control of p53 by Sir2alpha promotes cell survival under stress. Cell 107: 137-148.
20. McWilliam H, Li W, Uludag M, Squizzato S, Park YM, Buso N, Cowley AP, Lopez R. 2013. Analysis Tool Web Services from the EMBL-EBI. Nucleic Acids Res 41:W597-W600.
21. Muto S, Miyachi S. 1981. Light-induced conversion of nicotinamide adenine dinucleotide to nicotinamide adenine dinucleotide phosphate in higher plant leaves. Plant Physiol 68: 324-328.
22. Ohashi K, Kawai S, Murata K. 2012. Identification and characterization of a human mitochondrial NAD kinase. Nat Commun 3:1248.
23. Outten CE, Culotta VC. 2003. A novel NADH kinase is the mitochondrial source of NADPH in Saccharomyces cerevisiae. EMBO J 22: 2015-2024.
24. Pollak N, Dolle C, Ziegler M. 2007a. The power to reduce: Pyridine nucleotides-small molecules with a multitude of functions. Biochem J 402: 205-218.
25. Pollak N, Niere M, Ziegler M. 2007b. NAD kinase levels control the NADPH concentration in human cells. J Biol Chem 282: 33562-33571.
26. Raha S, Robinson BH. 2000. Mitochondria, oxygen free radicals, disease and ageing. Trends Biochem Sci 25: 502-508.
27. Schreiber V, Dantzer F, Ame JC, de Murcia G. 2006. Poly(ADP-ribose): Novel functions for an old molecule. Nat Rev Mol Cell Biol 7: 517-528.
28. Shi F, Kawai S, Mori S, Kono E, Murata K. 2005. Identification of ATP-NADH kinase isozymes and their contribution to supply of NADP(H) in Saccharomyces cerevisiae. FEBS J 272: 3337-3349.
29. Simon P, Dieter P, Bonzon M, Greppin H, Marme D. 1982. Calmodulin-dependent and independent NAD kinase activities from cytoplasmic and AT fractions of spinach (Spinacia oleracea L.). Plant Cell Rep 1: 119-122.
30. Smith JS, Brachmann CB, Celic I, Kenna MA, Muhammad S, Starai VJ, Avalos JL, Escalante-Semerena JC, Grubmeyer C, Wolberger C, Boeke JD. 2000. A phylogenetically conserved NAD + -dependent protein deacetylase activity in the Sir2 protein family. Proc Natl Acad Sci USA 97: 6658-6663.
31. Strand MK, Stuart GR, Longley MJ, Graziewicz MA, Dominick OC, Copeland WC. 2003. POS5 gene of Saccharomyces cerevisiae encodes a mitochondrial NADH kinase required for stability of mitochondrial DNA. Eukaryot Cell 2: 809-820.
32. Todisco S, Agrimi G, Castegna A, Palmieri F. 2006. Identification of the mitochondrial NAD+ transporter in Saccharomyces cerevisiae. J Biol Chem 281: 1524-1531.
33. Turner WL, Waller JC, Snedden WA. 2005. Identification, molecular cloning and functional characterization of a novel NADH kinase from Arabidopsis thaliana (thale cress). Biochem J 385: 217-223.
34. Turner WL, Waller JC, Vanderbeld B, Snedden WA. 2004. Cloning and characterization of two NAD kinases from Arabidopsis. identification of a calmodulin binding isoform. Plant Physiol 135: 1243-1255.
35. Valko M, Leibfritz D, Moncol J, Cronin MT, Mazur M, Telser J. 2007. Free radicals and antioxidants in normal physiological functions and human disease. Int J Biochem Cell Biol 39: 44-84.
36. Waller JC, Dhanoa PK, Schumann U, Mullen RT, Snedden WA. 2010. Subcellular and tissue localization of NAD kinases from Arabidopsis: Compartmentalization of de novo NADP biosynthesis. Planta 231: 305-317.
37. Williams MB, Jones HP. 1985. Calmodulin-dependent NAD kinase of human neutrophils. Arch Biochem Biophys 237: 80-87.
38. Wood JG, Rogina B, Lavu S, Howitz K, Helfand SL, Tatar M, Sinclair D. 2004. Sirtuin activators mimic caloric restriction and delay ageing in metazoans. Nature 430: 686-689.
39. Zhang R. 2013. MNADK, a novel liver-enriched mitochondrion-localized NAD kinase. Biol Open 2: 432-438.