Selective distal enhancer control of the Mmp13 gene identified through clustered regularly interspaced short palindromic repeat (CRISPR) genomic deletions

Journal of Biological Chemistry

Volumn 290, Issue 17, 2015, Pages 11093-11107

  Meyer, Mark B ^a   Benkusky, Nancy A ^a   Pike, J Wesley ^a  

^a UNIVERSITY OF WISCONSIN MADISON   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BINDING SITES; CELL PROLIFERATION; CHROMOSOMES; GENE EXPRESSION; GENES; MOBILE SECURITY; TRANSCRIPTION FACTORS;

BACTERIAL ARTIFICIAL CHROMOSOMES; CCAAT/ENHANCER-BINDING PROTEINS; CELLULAR PROLIFERATIONS; MATRIX METALLOPROTEINASE 13; OSTEOBLAST MATURATION; PARATHYROID HORMONES; SEQUENCING ANALYSIS; VITAMIN D RECEPTOR;

TRANSCRIPTION;

CALCITRIOL; CCAAT ENHANCER BINDING PROTEIN BETA; COLLAGENASE 3; TRANSCRIPTION FACTOR RUNX2; VITAMIN D RECEPTOR; CALCITRIOL RECEPTOR; MMP13 PROTEIN, MOUSE; RUNX2 PROTEIN, MOUSE; VITAMIN;

ANIMAL CELL; ARTICLE; BACTERIAL ARTIFICIAL CHROMOSOME; BINDING SITE; CELL MATURATION; CELL PROLIFERATION; CHROMATIN IMMUNOPRECIPITATION; CLUSTERED REGULARLY INTERSPACED SHORT PALINDROMIC REPEAT; CONTROLLED STUDY; ENHANCER REGION; GENE CONTROL; GENE DELETION; GENE EXPRESSION; GENE REPRESSION; GENETIC ENGINEERING; GENETIC RECOMBINATION; MMP13 GENE; MOUSE; MUTAGENESIS; NONHUMAN; OSTEOBLAST; PRIORITY JOURNAL; PROTEIN BINDING; RECEPTOR OCCUPANCY; RECEPTOR UPREGULATION; SEQUENCE ANALYSIS; SIGNAL TRANSDUCTION; ANIMAL; BIOSYNTHESIS; CELL LINE; GENE EXPRESSION REGULATION; GENETIC TRANSCRIPTION; GENETICS; INVERTED REPEAT; METABOLISM; NUCLEOTIDE SEQUENCE; PHYSIOLOGY;

BACTERIA (MICROORGANISMS);

ANIMALS; BASE SEQUENCE; CALCITRIOL; CELL LINE; CORE BINDING FACTOR ALPHA 1 SUBUNIT; ENHANCER ELEMENTS, GENETIC; GENE EXPRESSION REGULATION, ENZYMOLOGIC; INVERTED REPEAT SEQUENCES; MATRIX METALLOPROTEINASE 13; MICE; RECEPTORS, CALCITRIOL; SEQUENCE DELETION; SIGNAL TRANSDUCTION; TRANSCRIPTION, GENETIC; VITAMINS;

EID: 84928392328     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M115.648394     Document Type: Article

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