The microenvironment in mature b-cell malignancies: A target for new treatment strategies
Burger JA, Ghia P, Rosenwald A, Caligaris-Cappio F. The microenvironment in mature B-cell malignancies: a target for new treatment strategies. Blood. 2009;114(16):3367-3375.
The lymph node microenvironment promotes b-cell receptor signaling, nf-kappab activation, and tumor proliferation in chronic lymphocytic leukemia
Herishanu Y, Pérez-Galán P, Liu D, et al. The lymph node microenvironment promotes B-cell receptor signaling, NF-kappaB activation, and tumor proliferation in chronic lymphocytic leukemia. Blood. 2011;117(2):563-574.
Involvement of baff and april in the resistance to apoptosis of b-cll through an autocrine pathway
Kern C, Cornuel JF, Billard C, et al. Involvement of BAFF and APRIL in the resistance to apoptosis of B-CLL through an autocrine pathway. Blood. 2004;103(2):679-688.
Nurselike cells express baff and april, which can promote survival of chronic lymphocytic leukemia cells via a paracrine pathway distinct from that of sdf-1alpha
Nishio M, Endo T, Tsukada N, et al. Nurselike cells express BAFF and APRIL, which can promote survival of chronic lymphocytic leukemia cells via a paracrine pathway distinct from that of SDF-1alpha. Blood. 2005;106(3):1012-1020.
April but not blys serum levels are increased in chronic lymphocytic leukemia: Prognostic relevance of april for survival
Planelles L, Castillo-Gutiérrez S, Medema JP, Morales-Luque A, Merle-Béral H, Hahne M. APRIL but not BLyS serum levels are increased in chronic lymphocytic leukemia: prognostic relevance of APRIL for survival. Haematologica. 2007;92(9):1284-1285.
Development and characterization of april antagonistic monoclonal antibodies for treatment of b-cell lymphomas
Guadagnoli M, Kimberley FC, Phan U, et al. Development and characterization of APRIL antagonistic monoclonal antibodies for treatment of B-cell lymphomas. Blood. 2011;117(25): 6856-6865.
Chronic lymphocytic leukemia of emu-tcl1 transgenic mice undergoes rapid cell turnover that can be offset by extrinsic cd257 to accelerate disease progression
Enzler T, Kater AP, Zhang W, et al. Chronic lymphocytic leukemia of Emu-TCL1 transgenic mice undergoes rapid cell turnover that can be offset by extrinsic CD257 to accelerate disease progression. Blood. 2009;114(20): 4469-4476.
Human chronic lymphocytic leukemia modeled in mouse by targeted tcl1 expression
Bichi R, Shinton SA, Martin ES, et al. Human chronic lymphocytic leukemia modeled in mouse by targeted TCL1 expression. Proc Natl Acad Sci USA. 2002;99(10):6955-6960.
The design and characterization of receptor-selective april variants
Kimberley FC, van der Sloot AM, Guadagnoli M, et al. The design and characterization of receptor-selective APRIL variants. J Biol Chem. 2012; 287(44):37434-37446.
(2012)J Biol Chem, vol.287, Issue.44, pp. 37434-37446
Structure and function of the hematopoietic cancer niche: Focus on chronic lymphocytic leukemia
Schol Ed
Fecteau JF, Kipps TJ. Structure and function of the hematopoietic cancer niche: focus on chronic lymphocytic leukemia. Front Biosci (Schol Ed). 2012;4:61-73.