Mitogen-activated protein kinase signaling and its association with oxidative stress and apoptosis in lead-exposed hepatocytes

Environmental Toxicology

Volumn 30, Issue 5, 2015, Pages 513-529

  Mujaibel, Latifah M ^a   Kilarkaje, Narayana ^a  

^a KUWAIT UNIVERSITY   (Kuwait)

Author keywords

Apoptosis; Environmental toxicology; ERKs; Heavy metals; Hepatotoxicity; JNKs; Oxidative stress; P38 MAPK

Indexed keywords

ENZYME ACTIVITY; ENZYMES; HEAVY METALS; OXIDATIVE STRESS; PROTEINS; TOXICITY;

ENVIRONMENTAL TOXICOLOGY; ERKS; HEPATOTOXICITY; JNKS; P38 MAPK;

CELL DEATH;

LEAD; LEAD ACETATE; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 12; MITOGEN ACTIVATED PROTEIN KINASE 3; STRESS ACTIVATED PROTEIN KINASE 1; ANTIOXIDANT; ORGANOMETALLIC COMPOUND;

ADULT; ANIMAL EXPERIMENT; ANIMAL MODEL; APOPTOSIS; ARTICLE; CONFOCAL MICROSCOPY; CONTROLLED STUDY; DOWN REGULATION; ENVIRONMENTAL EXPOSURE; FEMALE; LIPID PEROXIDATION; LIVER TOXICITY; LIVER WEIGHT; LONG TERM EXPOSURE; MALE; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; SEX DIFFERENCE; TISSUE SECTION; UPREGULATION; WEIGHT CHANGE; WEIGHT GAIN; ANIMAL; DOSE RESPONSE; DRUG EFFECTS; LIVER CELL; METABOLISM; ORGAN SIZE; SEXUAL DEVELOPMENT; SIGNAL TRANSDUCTION; WISTAR RAT;

RATTUS NORVEGICUS;

ANIMALS; ANTIOXIDANTS; APOPTOSIS; DOSE-RESPONSE RELATIONSHIP, DRUG; FEMALE; HEPATOCYTES; LEAD; LIPID PEROXIDATION; MALE; MAP KINASE SIGNALING SYSTEM; MITOGEN-ACTIVATED PROTEIN KINASES; ORGAN SIZE; ORGANOMETALLIC COMPOUNDS; OXIDATIVE STRESS; RATS; RATS, WISTAR; SEX CHARACTERISTICS; WEIGHT GAIN;

EID: 84928285221     PISSN: 15204081     EISSN: 15227278     Source Type: Journal    
DOI: 10.1002/tox.21928     Document Type: Article

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