The redox status in rats treated with flaxseed oil and lead-induced hepatotoxicity

Biological Trace Element Research

Volumn 143, Issue 1, 2011, Pages 457-467

  Abdel Moneim, Ahmed E ^a   Dkhil, Mohamed A ^a,b   Al Quraishy, Saleh ^b  

^a Helwan University   (Egypt)

^b KING SAUD UNIVERSITY   (Saudi Arabia)

Author keywords

Flaxseed oil; Hepatotoxicity; Lead; Rat; Redox status

Indexed keywords

ALANINE AMINOTRANSFERASE; ALKALINE PHOSPHATASE; ASPARTATE AMINOTRANSFERASE; CATALASE; FLAXSEED OIL; GAMMA GLUTAMYLTRANSFERASE; GLUTATHIONE; GLUTATHIONE PEROXIDASE; GLUTATHIONE REDUCTASE; GLUTATHIONE TRANSFERASE; LEAD; NATURAL PRODUCT; NITRIC OXIDE; SUPEROXIDE DISMUTASE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DISEASE ASSOCIATION; DNA FRAGMENTATION; DRUG EFFECT; ENZYME ACTIVITY; ENZYME BLOOD LEVEL; HISTOPATHOLOGY; LINSEED; LIPID PEROXIDATION; LIVER PROTECTION; LIVER TOXICITY; MALE; NONHUMAN; OXIDATION REDUCTION STATE; OXIDATIVE STRESS; RAT;

ALANINE TRANSAMINASE; ALKALINE PHOSPHATASE; ANIMALS; ASPARTATE AMINOTRANSFERASES; BILIRUBIN; DNA FRAGMENTATION; GAMMA-GLUTAMYLTRANSFERASE; LEAD; LINSEED OIL; LIVER; MALE; OXIDATION-REDUCTION; RATS;

RATTUS;

EID: 80054772952     PISSN: 01634984     EISSN: 15590720     Source Type: Journal    
DOI: 10.1007/s12011-010-8882-z     Document Type: Article

References (52)

1. S Skerfving C Hogstedt H Welinder 2007 Broad overview of the history of Swedish occupational health research Scand J Work Environ Health 33 Suppl 1 6 19 18389568
2. F Barbosa Jr JE Tanus-Santos RF Gerlach PJ Parsons 2005 A critical review of biomarkers used for monitoring human exposure to lead: advantages, limitations, and future needs Environ Health Perspect 113 12 1669 1674 16330345 10.1289/ehp.7917 1:CAS:528:DC%2BD2MXhtleqsb3J
3. J Yu H Fujishiro H Miyataka TM Oyama T Hasegawa Y Seko, et al. 2009 Dichotomous effects of lead acetate on the expression of metallothionein in the liver and kidney of mice Biol Pharm Bull 32 6 1037 1042 19483311 10.1248/bpb.32.1037 1:CAS:528:DC%2BD1MXpvVymtbs%3D
4. GR Bratton J Zmudzki MC Bell LG Warnock 1981 Thiamin (vitamin b1) effects on lead intoxication and deposition of lead in tissues: therapeutic potential Toxicol Appl Pharmacol 59 1 164 172 7256755 10.1016/0041-008X(81)90464-6 1:CAS:528:DyaL3MXkslCrurw%3D
5. SJ Flora S Singh SK Tandon 1984 Prevention of lead intoxication by vitamin-B complex Z Gesamte Hyg 30 7 409 411 6485409 1:STN:280: DyaL2M%2FhvVGmtg%3D%3D
6. MG Traber L Packer 1995 Vitamin E: beyond antioxidant function Am J Clin Nutr 62 6 Suppl 1501S 1509S 7495251 1:CAS:528:DyaK28XmvFWquw%3D%3D
7. GO Korsrud JB Meldrum 1988 Effect of diet on the response in rats to lead acetate given orally or in the drinking water Biol Trace Elem Res 17 167 173 2484355 10.1007/BF02795454 1:CAS:528:DyaL1cXmt1Chsb0%3D
8. GO Korsrud JB Meldrum 1988 Effect on blood, liver, and kidney variables of age and of dosing rats with lead acetate orally or via the drinking water Biol Trace Elem Res 17 151 166 2484354 10.1007/BF02795453 1:CAS:528: DyaL1cXmt1Chsbw%3D
9. SL Cohen AM Moore WE Ward 2005 Flaxseed oil and inflammation-associated bone abnormalities in interleukin-10 knockout mice J Nutr Biochem 16 6 368 374 15936649 10.1016/j.jnutbio.2005.01.008 1:CAS:528:DC%2BD2MXltVehsb4%3D
10. K Vijaimohan M Jainu KE Sabitha S Subramaniyam C Anandhan CS Shyamala Devi 2006 Beneficial effects of alpha linolenic acid rich flaxseed oil on growth performance and hepatic cholesterol metabolism in high fat diet fed rats Life Sci 79 5 448 454 16490217 10.1016/j.lfs.2006.01.025 1:CAS:528: DC%2BD28XlsFGksLk%3D
11. MS Kurzer X Xu 1997 Dietary phytoestrogens Annu Rev Nutr 17 353 381 9240932 10.1146/annurev.nutr.17.1.353 1:CAS:528:DyaK2sXkvFGmtL0%3D
12. MM Jones MG Cherian 1990 The search for chelate antagonists for chronic cadmium intoxication Toxicology 62 1 1 25 2188397 10.1016/0300-483X(90)90027-E 1:CAS:528:DyaK3cXkslamtb4%3D
13. L Patrick 2002 Mercury toxicity and antioxidants: Part 1: role of glutathione and alpha-lipoic acid in the treatment of mercury toxicity Altern Med Rev 7 6 456 471 12495372
14. Y Ito Y Niiya H Kurita S Shima S Sarai 1985 Serum lipid peroxide level and blood superoxide dismutase activity in workers with occupational exposure to lead Int Arch Occup Environ Health 56 2 119 127 4055067 10.1007/BF00379383 1:CAS:528:DyaL28XnsVWgtw%3D%3D
15. AL Bhatia A Sharma S Patni AL Sharma 2007 Prophylactic effect of flaxseed oil against radiation-induced hepatotoxicity in mice Phytother Res 21 9 852 859 17486687 10.1002/ptr.2169 1:CAS:528:DC%2BD2sXhtFKgurnL
16. 2+-ATPase activities induced by the in vitro galactosaemia Pharmacol Res 49 5 475 479 14998558 10.1016/j.phrs.2003.11. 006 1:CAS:528:DC%2BD2cXhsleqt7k%3D
17. M Watabe Y Masuda S Nakajo T Yoshida Y Kuroiwa K Nakaya 1996 The cooperative interaction of two different signaling pathways in response to bufalin induces apoptosis in human leukemia U937 cells J Biol Chem 271 24 14067 14072 8662906 10.1074/jbc.271.24.14067 1:CAS:528:DyaK28Xjs1Oitr4%3D
18. S Reitman S Frankel 1957 A colorimetric method for the determination of serum glutamic oxalacetic and glutamic pyruvic transaminases Am J Clin Pathol 28 1 56 63 13458125 1:CAS:528:DyaG2sXpvFyiuw%3D%3D
19. M Schmidt J Eisenburg 1975 Serum bilirubin determination in newborn infants. A new micromethod for the determination of serum of plasma bilirubin in newborn infants Fortschr Med 93 30 1461 1466 1225803 1:CAS:528: DyaE28XktVeqtg%3D%3D
20. R Berkels S Purol-Schnabel R Roesen 2004 Measurement of nitric oxide by reconversion of nitrate/nitrite to NO Methods Mol Biol 279 1 8 15199232 1:CAS:528:DC%2BD2cXmsVOjurw%3D
21. H Ohkawa N Ohishi K Yagi 1979 Assay for lipid peroxides in animal tissues by thiobarbituric acid reaction Anal Biochem 95 2 351 358 36810 10.1016/0003-2697(79)90738-3 1:CAS:528:DyaE1MXksFaisbk%3D
22. GL Ellman 1959 Tissue sulfhydryl groups Arch Biochem Biophys 82 1 70 77 13650640 10.1016/0003-9861(59)90090-6 1:CAS:528:DyaG1MXotl2ksA%3D%3D
23. H Aebi 1984 Catalase in vitro Methods Enzymol 105 121 126 6727660 10.1016/S0076-6879(84)05016-3 1:CAS:528:DyaL2cXltVKis7s%3D
24. M Nishikimi N Appaji K Yagi 1972 The occurrence of superoxide anion in the reaction of reduced phenazine methosulfate and molecular oxygen Biochem Biophys Res Commun 46 2 849 854 4400444 10.1016/S0006-291X(72)80218-3 1:CAS:528:DyaE38Xps1Wisw%3D%3D
25. WH Habig MJ Pabst WB Jakoby 1974 Glutathione S-transferases. The first enzymatic step in mercapturic acid formation J Biol Chem 249 22 7130 7139 4436300 1:CAS:528:DyaE2MXltlahtg%3D%3D
26. DE Paglia WN Valentine 1967 Studies on the quantitative and qualitative characterization of erythrocyte glutathione peroxidase J Lab Clin Med 70 1 158 169 6066618 1:CAS:528:DyaF2sXks1Wjur8%3D
27. VM Factor A Kiss JT Woitach PJ Wirth SS Thorgeirsson 1998 Disruption of redox homeostasis in the transforming growth factor-alpha/c-myc transgenic mouse model of accelerated hepatocarcinogenesis J Biol Chem 273 25 15846 15853 9624185 10.1074/jbc.273.25.15846 1:CAS:528:DyaK1cXktVSls7g%3D
28. GO Ajayi TT Adeniyi DO Babayemi 2009 Hepatoprotective and some haematological effects of Allium sativum and vitamin C in lead-exposed wistar rats Inter J Med Med Sci 1 3 4
29. HL Needleman 1992 Effects of low levels of lead exposure Science 256 5055 294 295 1489377 10.1126/science.256.5055.294-a 1:STN:280:DyaK383ivFCmtQ%3D%3D
30. JR Miller KA Hudson-Edwards PJ Lechler D Preston MG Macklin 2004 Heavy metal contamination of water, soil and produce within riverine communities of the Rio Pilcomayo basin, Bolivia Sci Total Environ 320 2-3 189 209 15016507 1:CAS:528:DC%2BD2cXhvV2nu7Y%3D
31. P Pagliara A Chionna EC Carla S Caforio L Dini 2003 Lead nitrate and gadolinium chloride administration modify hepatocyte cell surfaces Cell Tissue Res 312 1 41 48 12684870 1:CAS:528:DC%2BD3sXjtFChsrc%3D
32. RC Patra D Swarup SK Dwivedi 2001 Antioxidant effects of alpha tocopherol, ascorbic acid and L-methionine on lead induced oxidative stress to the liver, kidney and brain in rats Toxicology 162 2 81 88 11337108 10.1016/S0300-483X(01)00345-6 1:CAS:528:DC%2BD3MXjtFCrurk%3D
33. AA El-Nekeety AA El-Kady MS Soliman NS Hassan MA Abdel-Wahhab 2009 Protective effect of Aquilegia vulgaris (L.) against lead acetate-induced oxidative stress in rats Food Chem Toxicol 47 9 2209 2215 19531368 10.1016/j.fct.2009.06.019 1:CAS:528:DC%2BD1MXps1eqs78%3D
34. MG Shalan MS Mostafa MM Hassouna SE El-Nabi A El-Refaie 2005 Amelioration of lead toxicity on rat liver with vitamin C and silymarin supplements Toxicology 206 1 1 15 15590105 10.1016/j.tox.2004.07.006 1:CAS:528: DC%2BD2cXhtVKksrzJ
35. OA Adaramoye DO Osaimoje AM Akinsanya CM Nneji MA Fafunso OG Ademowo 2008 Changes in antioxidant status and biochemical indices after acute administration of artemether, artemether-lumefantrine and halofantrine in rats Basic Clin Pharmacol Toxicol 102 4 412 418 18282195 10.1111/j.1742-7843.2008. 00211.x 1:CAS:528:DC%2BD1cXksFaqtbw%3D
36. V Sharma L Kansal A Sharma 2009 Prophylactic efficacy of Coriandrum sativum (Coriander) on testis of lead-exposed mice Biol Trace Elem Res 136 3 337 354 19902160 10.1007/s12011-009-8553-0
37. DS Herman M Geraldine T Venkatesh 2009 Influence of minerals on lead-induced alterations in liver function in rats exposed to long-term lead exposure J Hazard Mater 166 2-3 1410 1414 19167163 10.1016/j.jhazmat.2008.12.070
38. S Rahman S Sultana 2006 Chemopreventive activity of glycyrrhizin on lead acetate mediated hepatic oxidative stress and its hyperproliferative activity in Wistar rats Chem Biol Interact 160 1 61 69 16426592 10.1016/j.cbi.2005.12.003 1:CAS:528:DC%2BD28XhsF2hs78%3D
39. GT Ramesh AL Jadhav 2001 Levels of protein kinase C and nitric oxide synthase activity in rats exposed to sub chronic low level lead Mol Cell Biochem 223 1-2 27 33 11681719 10.1023/A:1017549003114 1:CAS:528:DC%2BD3MXnslGnsrk%3D
40. SM Deneke 2000 Thiol-based antioxidants Curr Top Cell Regul 36 151 180 10842751 10.1016/S0070-2137(01)80007-8 1:CAS:528:DC%2BD3cXivVehtbY%3D
41. N Ercal H Gurer-Orhan N Aykin-Burns 2001 Toxic metals and oxidative stress part I: mechanisms involved in metal-induced oxidative damage Curr Top Med Chem 1 6 529 539 11895129 10.2174/1568026013394831 1:CAS:528: DC%2BD3MXos1ait7s%3D
42. R Anane EE Creppy 2001 Lipid peroxidation as pathway of aluminium cytotoxicity in human skin fibroblast cultures: prevention by superoxide dismutase∈+∈catalase and vitamins E and C Hum Exp Toxicol 20 9 477 481 11776410 10.1191/096032701682693053 1:CAS:528:DC%2BD38XkslSgtg%3D%3D
43. LJ Lawton WE Donaldson 1991 Lead-induced tissue fatty acid alterations and lipid peroxidation Biol Trace Elem Res 28 2 83 97 1709034 10.1007/BF02863075 1:CAS:528:DyaK3MXhsFykurg%3D
44. A Sharma V Sharma L Kansal 2009 Therapeutic Effects of Allium sativum on Lead-induced Biochemical changes in Soft tissues of Swiss Albino Mice Phcog Mag 5 364 371 10.4103/0973-1296.58568
45. V Sharma A Sharma L Kansal 2010 The effect of oral administration of Allium sativum extracts on lead nitrate induced toxicity in male mice Food Chem Toxicol 48 3 928 936 20060875 10.1016/j.fct.2010.01.002 1:CAS:528: DC%2BC3cXit1Orur4%3D
46. V Sharma D Pandey 2010 Protective role of Tinospora cordifolia against lead-induced hepatotoxicity Toxicol Int 17 12 17 21042467 10.4103/0971-6580. 68343 1:STN:280:DC%2BC3cbktVWksQ%3D%3D
47. A Sharma V Sharma L Kansal 2010 Amelioration of lead induced hepatotoxicity by Allium sativum extracts in Swiss albino mice Libyan J Med 5 4621 10.4176/091107
48. DD Kitts YV Yuan AN Wijewickreme LU Thompson 1999 Antioxidant activity of the flaxseed lignan secoisolariciresinol diglycoside and its mammalian lignan metabolites enterodiol and enterolactone Mol Cell Biochem 202 1-2 91 100 10705999 10.1023/A:1007022329660 1:CAS:528:DC%2BD3cXhsFGjurk%3D
49. MG Hertog EJ Feskens PC Hollman MB Katan D Kromhout 1993 Dietary antioxidant flavonoids and risk of coronary heart disease: the Zutphen Elderly Study Lancet 342 8878 1007 1011 8105262 10.1016/0140-6736(93)92876-U 1:STN:280:DyaK2c%2FhvVajsQ%3D%3D
50. K Prasad 2005 Hypocholesterolemic and antiatherosclerotic effect of flax lignan complex isolated from flaxseed Atherosclerosis 179 2 269 275 15777541 10.1016/j.atherosclerosis.2004.11.012 1:CAS:528:DC%2BD2MXitlCjuro%3D
51. LU Thompson P Robb M Serraino F Cheung 1991 Mammalian lignan production from various foods Nutr Cancer 16 1 43 52 1656395 10.1080/01635589109514139 1:CAS:528:DyaK38Xht1Onu74%3D
52. AS Newairy HM Abdou 2009 Protective role of flax lignans against lead acetate induced oxidative damage and hyperlipidemia in rats Food Chem Toxicol 47 4 813 818 19271316 10.1016/j.fct.2009.01.012 1:CAS:528:DC%2BD1MXis1aqsrg%3D