Crystal structure of the P38α-MAPKAP kinase 2 heterodimer

Journal of Biological Chemistry

Volumn 282, Issue 13, 2007, Pages 9733-9739

  Ter Haar, Ernst ^a   Prabakhar, Prakash ^a   Liu, Xun ^a   Lepre, Christopher ^a  

^a VERTEX PHARMACEUTICALS   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DOCKING GROOVES; HETERODIMER INTERFACES; PROINFLAMMATORY CYTOKINES;

BIOCHEMISTRY; CELLS; CRYSTAL STRUCTURE; ENZYMES; PHOSPHORYLATION;

DIMERS;

HETERODIMER; ISOENZYME; MITOGEN ACTIVATED PROTEIN KINASE 14; MITOGEN ACTIVATED PROTEIN KINASE ACTIVATED PROTEIN KINASE 2; UNCLASSIFIED DRUG; ADENOSINE TRIPHOSPHATE; MAP KINASE ACTIVATED KINASE 2; MAP-KINASE-ACTIVATED KINASE 2; PROTEIN SERINE THREONINE KINASE;

ARTICLE; CARBOXY TERMINAL SEQUENCE; CRYSTAL STRUCTURE; ENZYME CONFORMATION; ENZYME PHOSPHORYLATION; ENZYME STRUCTURE; ENZYME SUBSTRATE; ISOENZYME ANALYSIS; PRIORITY JOURNAL; PROTEIN DOMAIN; REGULATORY MECHANISM; STRUCTURE ANALYSIS; BINDING SITE; CHEMISTRY; DIMERIZATION; HUMAN; METABOLISM; PROTEIN TERTIARY STRUCTURE; X RAY CRYSTALLOGRAPHY;

ADENOSINE TRIPHOSPHATE; BINDING SITES; CRYSTALLOGRAPHY, X-RAY; DIMERIZATION; HUMANS; MITOGEN-ACTIVATED PROTEIN KINASE 14; PROTEIN STRUCTURE, TERTIARY; PROTEIN-SERINE-THREONINE KINASES;

EID: 34248200476     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M611165200     Document Type: Article

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