Tolerance of formulas containing prebiotics in healthy, term infants

Journal of Pediatric Gastroenterology and Nutrition

Volumn 59, Issue 5, 2014, Pages 653-658

  Williams, Timberly ^a   Choe, Yong ^a   Price, Pamela ^a   Katz, Gary ^a   Suarez, Fabrizis ^a   Paule, Charles ^a   Mackey, Amy ^a  

^a ABBOTT LABORATORIES   (United States)

Author keywords

Oligosaccharides; Prebiotic; Stool; Tolerance

Indexed keywords

GALACTOSE OLIGOSACCHARIDE; PREBIOTIC AGENT; GALACTOSE; OLIGOSACCHARIDE;

ARTICLE; ARTIFICIAL MILK; BREAST MILK; CHILD GROWTH; CHILD SAFETY; CONTROLLED STUDY; DOUBLE BLIND PROCEDURE; FECES ANALYSIS; FEEDING BEHAVIOR; FEMALE; FOOD INTAKE; GASTROINTESTINAL TOLERANCE; GASTROINTESTINAL TRACT FUNCTION; HEAD CIRCUMFERENCE; HUMAN; HUMAN EXPERIMENT; MALE; MULTICENTER STUDY; NEWBORN; NORMAL HUMAN; NUTRITIONAL TOLERANCE; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL; RELATIVE DENSITY; URINALYSIS; VOMITING; CHEMISTRY; CLINICAL TRIAL; DEFECATION; DRUG EFFECTS; FECES; TERM BIRTH;

DEFECATION; DOUBLE-BLIND METHOD; FECES; FEMALE; GALACTOSE; HUMANS; INFANT FORMULA; INFANT, NEWBORN; MALE; MILK, HUMAN; OLIGOSACCHARIDES; PREBIOTICS; TERM BIRTH; VOMITING;

EID: 84928273953     PISSN: 02772116     EISSN: 15364801     Source Type: Journal    
DOI: 10.1097/MPG.0000000000000513     Document Type: Article

References (34)

1. Coppa GV, Zampini L, Galeazzi T, et al. Prebiotics in human milk: a review. Dig Liver Dis 2006;38(suppl 2):S291-4.
2. Neville MC, Morton J. Physiology and endocrine changes underlying human lactogenesis II. J Nutr 2001;131:3005S-8.
3. Bode L. Human milk oligosaccharides: prebiotics and beyond. Nutr Rev 2009;67(suppl 2):S183-91.
4. Meijer K, de Vos P, Priebe MG. Butyrate and other short-chain fatty acids as modulators of immunity: what relevance for health? Curr Opin Clin Nutr Metab Care 2010;13:715-21.
5. Macfarlane GT, Steed H, Macfarlane S. Bacterial metabolism and health-related effects of galacto-oligosaccharides and other prebiotics. J Appl Microbiol 2008;104:305-44.
6. Willemsen LE, Koetsier MA, van Deventer SJ, et al. Short chain fatty acids stimulate epithelial mucin 2 expression through differential effects on prostaglandin E (1) and E (2) production by intestinal myofibroblasts. Gut 2003;52:1442-7.
7. Cummings JH, Macfarlane GT, Englyst HN. Prebiotic digestion and fermentation. Am J Clin Nutr 2001;73:415S-20S.
8. Ben XM, Zhou XY, Zhao WH, et al. Supplementation of milk formula with galacto-oligosaccharides improves intestinal microflora and fermentation in term infants. Chin Med J (Engl) 2004;117:927-31.
9. Fanaro S, Jelinek J, Stahl B, et al. Acidic oligosaccharides from pectin hydrolysate as new component for infant formulae: effect on intestinal flora, stool characteristics, and pH. J Pediatr Gastroenterol Nutr 2005;41:186-90.
10. Moro G, Arslanoglu S, Stahl B, et al. A mixture of prebiotic oligosaccharides reduces the incidence of atopic dermatitis during the first six months of age. Arch Dis Child 2006;91:814-9.
11. Moro G, Minoli I, Mosca M, et al. Dosage-related bifidogenic effects of galacto- and fructooligosaccharides in formula-fed term infants. J Pediatr Gastroenterol Nutr 2002;34:291-5.
12. Arslanoglu S, Moro GE, Boehm G. Early supplementation of prebiotic oligosaccharides protects formula-fed infants against infections during the first 6 months of life. J Nutr 2007;137:2420-4.
13. Knol J, Scholtens P, Kafka C, et al. Colon microflora in infants fed formula with galacto- and fructo-oligosaccharides: more like breast-fed infants. J Pediatr Gastroenterol Nutr 2005;40:36-42.
14. Magne F, Hachelaf W, Suau A, et al. Effects on faecal microbiota of dietary and acidic oligosaccharides in children during partial formula feeding. J Pediatr Gastroenterol Nutr 2008;46:580-8.
15. Ben XM, Li J, Feng ZT, et al. Low level of galacto-oligosaccharide in infant formula stimulates growth of intestinal Bifidobacteria and Lactobacilli. World J Gastroenterol 2008;14:6564-8.
16. Salvini F, Riva E, Salvatici E, et al. A specific prebiotic mixture added to starting infant formula has long-lasting bifidogenic effects. J Nutr 2011;141:1335-9.
17. Brunser O, Figueroa G, Gotteland M, et al. Effects of probiotic or prebiotic supplemented milk formulas on fecal microbiota composition of infants. Asia Pac J Clin Nutr 2006;15:368-76.
18. Bakker-Zierikzee AM, Alles MS, Knol J, et al. Effects of infant formula containing a mixture of galacto- and fructo-oligosaccharides or viable Bifidobacterium animalis on the intestinal microflora during the first 4 months of life. Br J Nutr 2005;94:783-90.
19. Bakker-Zierikzee AM, Tol EA, Kroes H, et al. Faecal SIgA secretion in infants fed on pre- or probiotic infant formula. Pediatr Allergy Immunol 2006;17:134-40.
20. Costalos C, Kapiki A, Apostolou M, et al. The effect of a prebiotic supplemented formula on growth and stool microbiology of term infants. Early Hum Dev 2008;84:45-9.
21. Moro GE, Mosca F, Miniello V, et al. Effects of a new mixture of prebiotics on faecal flora and stools in term infants. Acta Paediatr Suppl 2003;91:77-9.
22. Ziegler E, Vanderhoof JA, Petschow B, et al. Term infants fed formula supplemented with selected blends of prebiotics grow normally and have soft stools similar to those reported for breast-fed infants. J Pediatr Gastroenterol Nutr 2007;44:359-64.
23. Nakamura N, Gaskins HR, Collier CT, et al. Molecular ecological analysis of fecal bacterial populations from term infants fed formula supplemented with selected blends of prebiotics. Appl Environ Microbiol 2009;75:1121-8.
24. Xia Q, Williams T, Hustead D, et al. Quantitative analysis of intestinal bacterial populations from term infants fed formula supplemented with fructo-oligosaccharides. J Pediatr Gastroenterol Nutr 2012;55:314-20.
25. Friedman JN, Goldman RD, Srivastava R, et al. Development of a clinical dehydration scale for use in children between 1 and 36 months of age. J Pediatr 2004;145:201-7.
26. Braegger C, Chmielewska A, Decsi T, et al. Supplementation of infant formula with probiotics and/or prebiotics: a systematic review and comment by the ESPGHAN committee on nutrition. J Pediatr Gastroenterol Nutr 2011;52:238-50.
27. Rao S, Srinivasjois R, Patole S. Prebiotic supplementation in full-term neonates: a systematic review of randomized controlled trials. Arch Pediatr Adolesc Med 2009;163:755-64.
28. Thomas DW, Greer FR. Probiotics and prebiotics in pediatrics. Pediatrics 2010;126:1217-31.
29. Arslanoglu S, Moro GE, Schmitt J, et al. Early dietary intervention with a mixture of prebiotic oligosaccharides reduces the incidence of allergic manifestations and infections during the first two years of life. J Nutr 2008;138:1091-5.
30. Grüber C, van Stuijvenberg M, Mosca F, et al. Reduced occurrence of early atopic dermatitis because of immunoactive prebiotics among lowatopy-risk infants. J Allergy Clin Immunol 2010;126:791-7.
31. Eiwegger T, Stahl B, Schmitt J, et al. Human milk-derived oligosaccharides and plant-derived oligosaccharides stimulate cytokine production of cord blood T-cells in vitro. Pediatr Res 2004;56:536-40.
32. Eiwegger T, Stahl B, Haidl P, et al. Prebiotic oligosaccharides: in vitro evidence for gastrointestinal epithelial transfer and immunomodulatory properties. Pediatr Allergy Immunol 2010;21:1179-88.
33. Shoaf K, Mulvey GL, Armstrong GD, et al. Prebiotic galactooligosaccharides reduce adherence of enteropathogenic Escherichia coli to tissue culture cells. Infect Immun 2006;74:6920-8.
34. Vos AP, M'Rabet L, Stahl B, et al. Immune-modulatory effects and potential working mechanisms of orally applied nondigestible carbohydrates. Crit Rev Immunol 2007;27:97-140.