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Volumn 9, Issue 6, 2015, Pages 2303-2310

Resveratrol suppresses TGF-β-induced VEGF synthesis in osteoblasts: Inhibition of the p44/p42 MAPKs and SAPK/JNK pathways

Author keywords

Osteoblast; Resveratrol; Transforming growth factor ; Vascular endothelial growth factor

Indexed keywords

MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE P38; RESVERATROL; SMAD PROTEIN; STRESS ACTIVATED PROTEIN KINASE; TRANSFORMING GROWTH FACTOR BETA; VASCULOTROPIN;

EID: 84928235199     PISSN: 17920981     EISSN: 17921015     Source Type: Journal    
DOI: 10.3892/etm.2015.2389     Document Type: Article
Times cited : (22)

References (27)
  • 1
    • 84863875184 scopus 로고    scopus 로고
    • An overview of the regulation of bone remodelling at the cellular level
    • Kular J, Tickner J, Chim SM and Xu J: An overview of the regulation of bone remodelling at the cellular level. Clin Biochem 45: 863-873, 2012.
    • (2012) Clin Biochem , vol.45 , pp. 863-873
    • Kular, J.1    Tickner, J.2    Chim, S.M.3    Xu, J.4
  • 3
    • 0036140080 scopus 로고    scopus 로고
    • Targeted and nontargeted bone remodeling: Relationship to basic multicellular unit origination and progression
    • Parfitt AM: Targeted and nontargeted bone remodeling: Relationship to basic multicellular unit origination and progression. Bone 30: 5-7, 2002.
    • (2002) Bone , vol.30 , pp. 5-7
    • Parfitt, A.M.1
  • 4
    • 70450187617 scopus 로고    scopus 로고
    • The regulation of TGFbeta signal transduction
    • Moustakas A and Heldin CH: The regulation of TGFbeta signal transduction. Development 136: 3699-3714, 2009.
    • (2009) Development , vol.136 , pp. 3699-3714
    • Moustakas, A.1    Heldin, C.H.2
  • 5
    • 67650506105 scopus 로고    scopus 로고
    • TGF-beta1-induced migration of bone mesenchymal stem cells couples bone resorption with formation
    • Tang Y, Wu X, Lei W, Pang L, Wan C, Shi Z, Zhao L, Nagy TR, Peng X, Hu J, et al: TGF-beta1-induced migration of bone mesenchymal stem cells couples bone resorption with formation. Nat Med 15: 757-765, 2009.
    • (2009) Nat Med , vol.15 , pp. 757-765
    • Tang, Y.1    Wu, X.2    Lei, W.3    Pang, L.4    Wan, C.5    Shi, Z.6    Zhao, L.7    Nagy, T.R.8    Peng, X.9    Hu, J.10
  • 6
    • 0036225281 scopus 로고    scopus 로고
    • Reaching a genetic and molecular understanding of skeletal development
    • Karsenty G and Wagner EF: Reaching a genetic and molecular understanding of skeletal development. Dev Cell 2: 389-406, 2002.
    • (2002) Dev Cell , vol.2 , pp. 389-406
    • Karsenty, G.1    Wagner, E.F.2
  • 7
    • 84899651687 scopus 로고    scopus 로고
    • Targeting TGFβ signaling in subchondral bone and articular cartilage homeostasis
    • Zhen G and Cao X: Targeting TGFβ signaling in subchondral bone and articular cartilage homeostasis. Trends Pharmacol Sci 35: 227-236, 2014.
    • (2014) Trends Pharmacol Sci , vol.35 , pp. 227-236
    • Zhen, G.1    Cao, X.2
  • 8
    • 84872410777 scopus 로고    scopus 로고
    • VEGF and bone cell signalling: An essential vessel for communication?
    • Clarkin CE and Gerstenfeld LC: VEGF and bone cell signalling: An essential vessel for communication? Cell Biochem Funct 31: 1-11, 2013.
    • (2013) Cell Biochem Funct , vol.31 , pp. 1-11
    • Clarkin, C.E.1    Gerstenfeld, L.C.2
  • 9
    • 0038172625 scopus 로고    scopus 로고
    • Involvement of MAP kinases in TGF-beta-stimulated vascular endothelial growth factor synthesis in osteoblasts
    • Tokuda H, Hatakeyama D, Akamatsu S, Tanabe K, Yoshida M, Shibata T and Kozawa O: Involvement of MAP kinases in TGF-beta-stimulated vascular endothelial growth factor synthesis in osteoblasts. Arch Biochem Biophys 415: 117-125, 2003.
    • (2003) Arch Biochem Biophys , vol.415 , pp. 117-125
    • Tokuda, H.1    Hatakeyama, D.2    Akamatsu, S.3    Tanabe, K.4    Yoshida, M.5    Shibata, T.6    Kozawa, O.7
  • 10
    • 17444363727 scopus 로고    scopus 로고
    • SAPK/JNK plays a role in transforming growth factor-beta-induced VEGF synthesis in osteoblasts
    • Kanno Y, Ishisaki A, Yoshida M, Tokuda H, Numata O and Kozawa O: SAPK/JNK plays a role in transforming growth factor-beta-induced VEGF synthesis in osteoblasts. Horm Metab Res 37: 140-145, 2005.
    • (2005) Horm Metab Res , vol.37 , pp. 140-145
    • Kanno, Y.1    Ishisaki, A.2    Yoshida, M.3    Tokuda, H.4    Numata, O.5    Kozawa, O.6
  • 11
    • 3943054839 scopus 로고    scopus 로고
    • The Sir2 family of protein deacetylases
    • Blander G and Guarente L: The Sir2 family of protein deacetylases. Annu Rev Biochem 73: 417-435, 2004.
    • (2004) Annu Rev Biochem , vol.73 , pp. 417-435
    • Blander, G.1    Guarente, L.2
  • 12
    • 33845442520 scopus 로고    scopus 로고
    • In vino veritas: A tale of two sirt1s?
    • Koo SH and Montminy M: In vino veritas: A tale of two sirt1s? Cell 127: 1091-1093, 2006.
    • (2006) Cell , vol.127 , pp. 1091-1093
    • Koo, S.H.1    Montminy, M.2
  • 13
    • 0026651085 scopus 로고
    • Wine, alcohol, platelets, and the French paradox for coronary heart disease
    • Renaud S and de Lorgeril M: Wine, alcohol, platelets, and the French paradox for coronary heart disease. Lancet 339: 1523-1526, 1992.
    • (1992) Lancet , vol.339 , pp. 1523-1526
    • Renaud, S.1    De Lorgeril, M.2
  • 16
    • 84891596798 scopus 로고    scopus 로고
    • Resveratrol suppresses prostaglandin F(2α)-induced osteoprotegerin synthesis in osteoblasts: Inhibition of the MAP kinase signaling
    • Kuroyanagi G, Tokuda H, Matsushima-Nishiwaki R, Kondo A, Mizutani J, Kozawa O and Otsuka T: Resveratrol suppresses prostaglandin F(2α)-induced osteoprotegerin synthesis in osteoblasts: Inhibition of the MAP kinase signaling. Arch Biochem Biophys 542: 39-45, 2014.
    • (2014) Arch Biochem Biophys , vol.542 , pp. 39-45
    • Kuroyanagi, G.1    Tokuda, H.2    Matsushima-Nishiwaki, R.3    Kondo, A.4    Mizutani, J.5    Kozawa, O.6    Otsuka, T.7
  • 18
    • 0020678843 scopus 로고
    • In vitro differentiation and calcification in a new clonal osteogenic cell line derived from newborn mouse calvaria
    • Sudo H, Kodama HA, Amagai Y, Yamamoto S and Kasai S: In vitro differentiation and calcification in a new clonal osteogenic cell line derived from newborn mouse calvaria. J Cell Biol 96: 191-198, 1983.
    • (1983) J Cell Biol , vol.96 , pp. 191-198
    • Sudo, H.1    Kodama, H.A.2    Amagai, Y.3    Yamamoto, S.4    Kasai, S.5
  • 19
    • 0026541952 scopus 로고
    • Cross-talk regulation between cyclic AMP production and phosphoinositide hydrolysis induced by prostaglandin E2 in osteoblast-like cells
    • Kozawa O, Tokuda H, Miwa M, Kotoyori J and Oiso Y: Cross-talk regulation between cyclic AMP production and phosphoinositide hydrolysis induced by prostaglandin E2 in osteoblast-like cells. Exp Cell Res 198: 130-134, 1992.
    • (1992) Exp Cell Res , vol.198 , pp. 130-134
    • Kozawa, O.1    Tokuda, H.2    Miwa, M.3    Kotoyori, J.4    Oiso, Y.5
  • 20
    • 0034609681 scopus 로고    scopus 로고
    • Retinal VEGF mRNA measured by SYBR green I fluorescence: A versatile approach to quantitative PCR
    • Simpson DA, Feeney S, Boyle C and Stitt AW: Retinal VEGF mRNA measured by SYBR green I fluorescence: A versatile approach to quantitative PCR. Mol Vis 6: 178-183, 2000.
    • (2000) Mol Vis , vol.6 , pp. 178-183
    • Simpson, D.A.1    Feeney, S.2    Boyle, C.3    Stitt, A.W.4
  • 21
    • 0014949207 scopus 로고
    • Cleavage of structural proteins during the assembly of the head of bacteriophage T4
    • Laemmli UK: Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature 227: 680-685, 1970.
    • (1970) Nature , vol.227 , pp. 680-685
    • Laemmli, U.K.1
  • 22
    • 0030058621 scopus 로고    scopus 로고
    • Modulation of the stress-induced synthesis of hsp27 and alpha B-crystallin by cyclic AMP in C6 rat glioma cells
    • Kato K, Ito H, Hasegawa K, Inaguma Y, Kozawa O and Asano T: Modulation of the stress-induced synthesis of hsp27 and alpha B-crystallin by cyclic AMP in C6 rat glioma cells. J Neurochem 66: 946-950, 1996.
    • (1996) J Neurochem , vol.66 , pp. 946-950
    • Kato, K.1    Ito, H.2    Hasegawa, K.3    Inaguma, Y.4    Kozawa, O.5    Asano, T.6
  • 23
    • 36749087548 scopus 로고    scopus 로고
    • Small molecule activators of SIRT1 as therapeutics for the treatment of type 2 diabetes
    • Milne JC, Lambert PD, Schenk S, et al: Small molecule activators of SIRT1 as therapeutics for the treatment of type 2 diabetes. Nature 450: 712-716, 2007.
    • (2007) Nature , vol.450 , pp. 712-716
    • Milne, J.C.1    Lambert, P.D.2    Schenk, S.3
  • 24
    • 58149216052 scopus 로고    scopus 로고
    • Signaling cross-talk between TGF-beta/BMP and other pathways
    • Guo X and Wang XF: Signaling cross-talk between TGF-beta/BMP and other pathways. Cell Res 19: 71-88, 2009.
    • (2009) Cell Res , vol.19 , pp. 71-88
    • Guo, X.1    Wang, X.F.2
  • 25
    • 0141719702 scopus 로고    scopus 로고
    • Small molecule activators of sirtuins extend Saccharomyces cerevisiae lifespan
    • Howitz KT, Bitterman KJ, Cohen HY, et al: Small molecule activators of sirtuins extend Saccharomyces cerevisiae lifespan. Nature 425: 191-196, 2003.
    • (2003) Nature , vol.425 , pp. 191-196
    • Howitz, K.T.1    Bitterman, K.J.2    Cohen, H.Y.3
  • 26
    • 33751072349 scopus 로고    scopus 로고
    • Resveratrol improves health and survival of mice on a high-calorie diet
    • Baur JA, Pearson KJ, Price NL, et al: Resveratrol improves health and survival of mice on a high-calorie diet. Nature 444: 337-342, 2006.
    • (2006) Nature , vol.444 , pp. 337-342
    • Baur, J.A.1    Pearson, K.J.2    Price, N.L.3
  • 27
    • 24944497786 scopus 로고    scopus 로고
    • Non-Smad TGF-beta signals
    • Moustakas A and Heldin CH: Non-Smad TGF-beta signals. J Cell Sci 118: 3573-3584, 2005.
    • (2005) J Cell Sci , vol.118 , pp. 3573-3584
    • Moustakas, A.1    Heldin, C.H.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.