Engineered bromodomains to explore the acetylproteome

Proteomics

Volumn 15, Issue 9, 2015, Pages 1470-1475

  Bryson, Bryan D ^a,b   Del rosario, Amanda M ^b   Gootenberg, Jonathan S ^a   Yaffe, Michael B ^a,b   White, Forest M ^a,b  

^a Massachusetts Institute of Technology Cambridge   (United States)

^b MASSACHUSETTS INSTITUTE OF TECHNOLOGY   (United States)

Author keywords

Affinity reagent; Bromodomain; Lysine acetylation; Posttranslational modification; Protein engineering; Technology

Indexed keywords

RECOMBINANT PROTEIN; BDF1 PROTEIN, S CEREVISIAE; DNA BINDING PROTEIN; HISTONE; LYSINE; PEPTIDE; RSC COMPLEX, S CEREVISIAE; SACCHAROMYCES CEREVISIAE PROTEIN; TRANSCRIPTION FACTOR;

AMINO ACID SEQUENCE; ARTICLE; ENZYME SPECIFICITY; HISTONE ACETYLATION; MASS SPECTROMETRY; METABOLIC REGULATION; NONHUMAN; PEPTIDE LIBRARY; PRIORITY JOURNAL; PROTEIN ACETYLATION; PROTEIN DOMAIN; PROTEIN ENGINEERING; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; PROTEIN PROTEIN INTERACTION; REVERSED PHASE HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; ACETYLATION; CHEMISTRY; GENETICS; HUMAN; METABOLISM; MOLECULAR GENETICS; PROCEDURES; PROTEIN PROCESSING; PROTEIN TERTIARY STRUCTURE; PROTEOMICS; SACCHAROMYCES CEREVISIAE; TANDEM MASS SPECTROMETRY;

ACETYLATION; AMINO ACID SEQUENCE; DNA-BINDING PROTEINS; HISTONES; HUMANS; LYSINE; MOLECULAR SEQUENCE DATA; PEPTIDES; PROTEIN ENGINEERING; PROTEIN PROCESSING, POST-TRANSLATIONAL; PROTEIN STRUCTURE, TERTIARY; PROTEOMICS; RECOMBINANT PROTEINS; SACCHAROMYCES CEREVISIAE; SACCHAROMYCES CEREVISIAE PROTEINS; TANDEM MASS SPECTROMETRY; TRANSCRIPTION FACTORS;

EID: 84928211218     PISSN: 16159853     EISSN: 16159861     Source Type: Journal    
DOI: 10.1002/pmic.201400401     Document Type: Article

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