Aryl hydrocarbon receptor mediates both proinflammatory and anti-inflammatory effects in lipopolysaccharide-activated microglia

GLIA

Volumn 63, Issue 7, 2015, Pages 1138-1154

  Lee, Yi Hsuan ^a   Lin, Chun Hua ^b   Hsu, Pei Chien ^a   Sun, Yu Yo ^c   Huang, Yu Jie ^a   Zhuo, Jiun Horng ^d,e   Wang, Chen Yu ^a   Gan, Yu Ling ^a   Hung, Chia Chi ^d   Kuan, Chia Yi ^c   Shie, Feng Shiun ^e  

^a NATIONAL YANG MING UNIVERSITY   (Taiwan)

^b Kang Ning Junior College of Medical Care and Management   (Taiwan)

^c EMORY UNIVERSITY SCHOOL OF MEDICINE   (United States)

^d TAIPEI MEDICAL UNIVERSITY   (Taiwan)

^e NATIONAL HEALTH RESEARCH INSTITUTES   (Taiwan)

Author keywords

Cytochrome P450 1A1; Inflammatory neurotoxicity; MEK1 2; NF kappaB; TNFalpha

Indexed keywords

1,4 DIAMINO 1,4 BIS(2 AMINOPHENYLTHIO) 2,3 DICYANOBUTADIENE; 4 (4 FLUOROPHENYL) 2 (4 METHYLSULFINYLPHENYL) 5 (4 PYRIDYL)IMIDAZOLE; ANTHRA[1,9 CD]PYRAZOL 6(2H) ONE; AROMATIC HYDROCARBON RECEPTOR; CYCLOOXYGENASE 2; CYTOCHROME P450 1A1; ELLIPTICINE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INDUCIBLE NITRIC OXIDE SYNTHASE; LIPOPOLYSACCHARIDE; MITOGEN ACTIVATED PROTEIN KINASE KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE KINASE 2; PARTHENOLIDE; STRESS ACTIVATED PROTEIN KINASE; SYNAPTOPHYSIN; SYNAPTOTAGMIN I; TRANSCRIPTION FACTOR RELA; TUMOR NECROSIS FACTOR ALPHA; AHR PROTEIN, MOUSE; BASIC HELIX LOOP HELIX TRANSCRIPTION FACTOR; CHROMATIN; MAP2K1 PROTEIN, MOUSE; MAP2K2 PROTEIN, MOUSE; NOS2 PROTEIN, MOUSE;

ANIMAL CELL; ANTIINFLAMMATORY ACTIVITY; ARTICLE; BONE MARROW CELL; BRAIN CORTEX; CELL DENSITY; CHROMATIN IMMUNOPRECIPITATION; CONTROLLED STUDY; DRUG ACTIVITY; ENZYME DEGRADATION; FEMALE; GENE EXPRESSION; GENETIC TRANSCRIPTION; IC50; IMMUNE RESPONSE; IMMUNOFLUORESCENCE TEST; IMMUNOHISTOCHEMISTRY; IMMUNOREACTIVITY; LIGAND BINDING; MACROPHAGE; MICROGLIA; MICROGLIAL CELL CULTURE; MOUSE; NERVOUS SYSTEM INFLAMMATION; NONHUMAN; PRIORITY JOURNAL; PROINFLAMMATORY EFFECT; PROMOTER REGION; PROTEIN EXPRESSION; RNA INTERFERENCE; SIGNAL TRANSDUCTION; UPREGULATION; WESTERN BLOTTING; XENOBIOTIC METABOLISM; ANIMAL; BAGG ALBINO MOUSE; CELL CULTURE; CELL DEATH; CELL LINE; CHROMATIN; GENE SILENCING; GENETICS; IMMUNOLOGY; KNOCKOUT MOUSE; METABOLISM; NERVE CELL; PHYSIOLOGY;

ANIMALS; BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTORS; CELL DEATH; CELL LINE; CELLS, CULTURED; CEREBRAL CORTEX; CHROMATIN; CYTOCHROME P-450 CYP1A1; GENE KNOCKDOWN TECHNIQUES; LIPOPOLYSACCHARIDES; MAP KINASE KINASE 1; MAP KINASE KINASE 2; MICE, INBRED BALB C; MICE, KNOCKOUT; MICROGLIA; NEURONS; NITRIC OXIDE SYNTHASE TYPE II; RECEPTORS, ARYL HYDROCARBON; SIGNAL TRANSDUCTION; TUMOR NECROSIS FACTOR-ALPHA;

EID: 84928209293     PISSN: 08941491     EISSN: 10981136     Source Type: Journal    
DOI: 10.1002/glia.22805     Document Type: Article

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