Distribution of mRNAs encoding the arylhydrocarbon receptor, arylhydrocarbon receptor nuclear translocator, and arylhydrocarbon receptor nuclear translocator-2 in the rat brain and brainstem

Journal of Comparative Neurology

Volumn 427, Issue 3, 2000, Pages 428-439

  Petersen, Sandra L ^a   Curran, Meredith A ^a   Marconi, Sharon A ^a   Carpenter, Clifford D ^a   Lubbers, Laura S ^a   McAbee, Michael D ^a  

^a UNIVERSITY OF MASSACHUSETTS   (United States)

Author keywords

Appetite; Dioxins; DRE; Neurotoxicity; XRE

Indexed keywords

AROMATIC HYDROCARBON RECEPTOR; ARYLHYDROCARBON RECEPTOR NUCLEAR TRANSLOCATOR 2; CARRIER PROTEIN; DIGOXIN; HYPOXIA INDUCIBLE FACTOR 1BETA; MESSENGER RNA; UNCLASSIFIED DRUG;

ANIMAL TISSUE; ARCUATE NUCLEUS; ARTICLE; BRAIN; BRAIN REGION; BRAIN STEM; CONTROLLED STUDY; DIMERIZATION; DORSAL RAPHE NUCLEUS; GENE EXPRESSION; HISTOCHEMISTRY; HYPOTHALAMUS; HYPOTHALAMUS VENTROMEDIAL NUCLEUS; IN SITU HYBRIDIZATION; MALE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; RAPHE NUCLEUS; RAT; SOLITARY TRACT NUCLEUS; SUPRACHIASMATIC NUCLEUS; THALAMUS MIDLINE NUCLEUS;

ANIMALS; ARYL HYDROCARBON RECEPTOR NUCLEAR TRANSLOCATOR; BRAIN STEM; CEREBELLUM; DNA-BINDING PROTEINS; HYPOTHALAMUS; IN SITU HYBRIDIZATION; MALE; PHOSPHORUS RADIOISOTOPES; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, ARYL HYDROCARBON; RNA, MESSENGER; TELENCEPHALON; THALAMUS; TRANSCRIPTION FACTORS;

EID: 0034694248     PISSN: 00219967     EISSN: None     Source Type: Journal    
DOI: 10.1002/1096-9861(20001120)427:3<428::AID-CNE9>3.0.CO;2-P     Document Type: Article

References (51)

1. The Seveso studies on early and long-term effects of dioxin exposure: A review
2. Tetrachlorodibenzo-p-dioxin alters rat hypothalamic endorphin and mu opioid receptors
3. The mechanism of dioxin toxicity: Relationship to risk assessment
4. Cloning of the Ah-receptor cDNA reveals a distinctive ligand-activated transcription factor
5. Tissue specific expression of the rat Ah-receptor and ARNT mRNAs
6. Relationship of the wasting syndrome to lethality in rats treated with 2, 3, 7, 8-tetrachlorodibenzo-p-dioxin
7. Aryl hydrocarbon hydroxylase of rat brain mitochondria, properties of, and effect of inhibitors and inducers on enzyme activity
8. Toxicology of dioxins and related chemicals
9. Cloning and expression of a human Ah receptor cDNA
10. Cloning and selective expression in brain and kidney of ARNT2 homologous to the Ah receptor nuclear translocator (ARNT)
11. cDNA cloning and structure of mouse putative Ah receptor
12. Differential induction of two 2, 3, 7, 8-tetrachlorodibenzo-p-dioxin inducible forms of cytochrome P-450 in extrahepatic versus hepatic tissues
13. The PAS superfamily: Sensors of environmental and developmental signals
14. cDNA cloning and tissue-specific expression of a novel basic helix-loop-helix/PAS factor (Arnt2) with close sequence similarity to the aryl hydrocarbon receptor nuclear translocator (Arnt)
15. Subnuclear organization of the human caudal nucleus of the solitary tract
16. Regional and subcellular distribution of cytochrome P450-dependent drug metabolism in monkey brain. The olfactory bulb and the mitochondrial fraction have high levels of activity
17. Expression of ARNT, ARNT2, HIF1a, HIF2a and Ah receptor mRNAs in the developing mouse
18. Circadian alterations in prolactin, corticosterone, and thyroid hormone levels and down-regulation of prolactin receptor activity by 2, 3, 7, 8-tetrachlorodibenzo-p-dioxin
19. The dioxin receptor and its nuclear translocator in the rat brain
20. Interacting appetite-regulating pathways in the hypothalamic regulation of body weight
21. Hypophagia-induced weight loss in mice, rats and guinea pigs treated with 2, 3, 7, 8-tetrachlorodibenzo-p-dioxin
22. Hypothalamic serotonin: Pharmacological, biochemical and behavioral analysis of its feeding suppressive action
23. Cytochrome P-450 b and c in the rat brain and pituitary gland
24. Serotonergic innervation of the forebrain: Effect of lesions on serotonin and tryptophan hydroxylase levels
25. Use of dual-label in situ hybridization histochemistry to determine the receptor complement of specific neurons
26. GABAA receptor subunit mRNAs in cells of the preoptic area: Colocalization with LHRH mRNA using dual-label in situ hybridization histochemistry
27. Examination of steroid-induced changes in LHRH gene transcription using 33P- and 35S-labeled probes specific for intron 2
28. The wasting syndrome in 2, 3, 7, 8-tetrachlorodibenzo-p-dioxin toxicity: Basic features and their interpretation
29. Remarkable residual alterations in responses to feeding regulatory challenges in Han/Wistar rats after recovery from the acute toxicity of 2, 3, 7, 8-tetrachlorodibenzo-p-dioxin (TCDD)
30. Short-term toxicity of 2, 3, 7, 8-tetrachlorodibenzo-p-dioxin in laboratory animals: Effects, mechanisms and animal models
31. Tissue distribution, metabolism, and excretion of 14C-TCDD in a TCDD-susceptible and a TCDD-resistant rat strain
32. 2, 3, 7, 8-Tetrachlorodibenzo-p-dioxin and related aromatic hydrocarbons: Examination of the mechanisms of toxicity
33. Aryl hydrocarbon receptor-mediated signal transduction
34. Hypothalamic site of action of 2, 3, 7, 8-tetrachlorodibenzo-p-dioxin (TCDD)
35. Ah receptor agonists as endocrine disruptors: Antiestrogenic activity and mechanisms
36. Comparative toxicology and mechanism of action of polychlorinated dibenzo-p-dioxins and dibenzofurans
37. Modulation of gene expression and endocrine response pathways by 2, 3, 7, 8-tetrachlorodibenzo-p-dioxin and related compounds
38. Absolute requirement of aryl hydrocarbon receptor nuclear translocator protein for gene activation by hypoxia
39. Learning in monkeys exposed to 2, 3, 7, 8-tetrachlorodibenzo-p-dioxin (TCDD)
40. Effects of 2, 3, 7, 8-tetrachlorodibenzo-p-dioxin on behavior of monkeys in peer groups
41. Regional distribution and expression modulation of cytochrome P-450 and epoxide hydrolase mRNAs in the rat brain
42. Body weight regulation in rats treated with 2, 3, 7, 8-tetrachlorodibenzo-p-dioxin
43. Learning and memory in rats gestationally and lactationally exposed to 2, 3, 7, 8-tetrachlorodibenzo-p-dioxin (TCDD)
44. Expression of basic helix-loop-helix/PAS genes in the mouse suprachiasmatic nucleus
45. 2, 3, 7, 8-Tetrachlorodibenzo-p-dioxin-induced anorexia and wasting syndrome in rats: Aggravation after ventromedial hypothalamic lesion
46. 2, 3, 7, 8-Tetrachlorodibenzo-p-dioxin (TCDD) induced ethoxyresorufin-o-deethylase (EROD) and aldehyde dehydrogenase (ALDH3) activities in the brain and liver. A comparison between the most TCDD-susceptible and the most TCDD-resistant rat strains
47. Characterization of 2, 3, 7, 8-tetrachlorodibenzo-p-dioxin-induced brain serotonin metabolism in the rat
48. Dose response and time course of alterations in tryptophan metabolism by 2, 3, 7, 8-tetrachlorodibenzo-p-dioxin in the most TCDD-susceptible and the most TCDD-resistant rat strain: Relationship with lethality
49. Biochemical effects of 2, 3, 7, 8-tetrachlorodibenzo-p-dioxin (TCDD) and related compounds on the central nervous system
50. Induction of cytochrome P4501A1