Association of polymorphisms in toll-like receptors 4 and 9 with risk of pulmonary Tuberculosis: A meta-analysis

Medical Science Monitor

Volumn 21, Issue , 2015, Pages 1097-1106

  Zhao, Lianli ^a   Liu, Kehun ^a   Kong, Xiangjun ^b   Tao, Zhenxia ^a   Wang, Yanxia ^a   Liu, Ying ^a  

^a CANGZHOU CENTRAL HOSPITAL   (China)

^b NONE

Author keywords

Meta analysis; Polymorphism; Pulmonary; Single nucleotide; Toll like receptors; Tuberculosis

Indexed keywords

TOLL LIKE RECEPTOR 4; TOLL LIKE RECEPTOR 9; TLR4 PROTEIN, HUMAN; TLR9 PROTEIN, HUMAN;

AFRICAN; ARTICLE; ASIAN; DISEASE ASSOCIATION; DISEASE PREDISPOSITION; GENOTYPE; HUMAN; LUNG TUBERCULOSIS; META ANALYSIS; POPULATION RISK; RISK FACTOR; SENSITIVITY ANALYSIS; SINGLE NUCLEOTIDE POLYMORPHISM; GENETIC ASSOCIATION; GENETIC PREDISPOSITION; GENETICS; ODDS RATIO; PUBLISHING;

GENETIC ASSOCIATION STUDIES; GENETIC PREDISPOSITION TO DISEASE; HUMANS; ODDS RATIO; POLYMORPHISM, SINGLE NUCLEOTIDE; PUBLICATION BIAS; RISK FACTORS; TOLL-LIKE RECEPTOR 4; TOLL-LIKE RECEPTOR 9; TUBERCULOSIS, PULMONARY;

EID: 84928165487     PISSN: 12341010     EISSN: 16433750     Source Type: Journal    
DOI: 10.12659/MSM.893755     Document Type: Article

References (47)

1. Russell DG, VanderVen BC, Lee W et al: Mycobacterium tuberculosis wears what it eats. Cell Host Microbe, 2010; 8: 68–76
2. Stop TB partnership: The global plan to Stop TB. 2011-2015
3. McShane H: Susceptibility to tuberculosis – the importance of the pathogen as well as the host. Clin Exp Immunol, 2003; 133: 20–21
4. Boechat AL, Ogusku MM, Sadahiro A, dos Santos MC: Association between the PTPN22 1858C/T gene polymorphism and tuberculosis resistance. Infect Genet Evol, 2013; 16: 310–13
5. Thada S, Valluri VL, Gaddam SL: Influence of Toll-like receptor gene polymorphisms to tuberculosis susceptibility in humans. Scand J Immunol, 2013; 78: 221–29
6. Liu G, Zhang L, Zhao Y: Modulation of immune responses through direct activation of Toll-like receptors to T cells. Clin Exp Immunol, 2010; 160: 168–75
7. Lisa C, Moira K, Steven K, Ian S: The expression and roles of Toll-like receptors in the biology of the human neutrophil. J Leuko Biol, 2005; 77: 886–92
8. Krutzik SR, Modlin RL: The role of Toll-like receptors in combating mycobacteria. Semin Immunol, 2004; 16: 35–41
9. Jo EK: Mycobacterial interaction with innate receptors: TLRs, C-type lectins, and NLRs. Curr Opin Infect Dis, 2008; 21: 279–86
10. Yamamoto M, Sato S, Hemmi H et al: Role of adaptor TRIF in the MyD88- independent toll-like receptor signaling pathway. Science, 2003; 301: 640–43
11. Xu Y, Jagannath C, Liu XD, Sharafkhaneh A et al: Toll-like receptor 4 is a sensor for autophagy associated with innate immunity. Immunity, 2007; 27: 135–44
12. Covert MW, Leung TH, Gaston JE, Baltimore D: Achieving stability of lipopolysaccharide- induced NF-kappaB activation. Science, 2005; 309: 1854–57
13. Reiling N, Holscher C, Fehrenbach A et al: Cutting edge: Toll-like receptor (TLR)2- and TLR4-mediated pathogen recognition in resistance to airborne infection with Mycobacterium tuberculosis. J Immunol, 2002; 169: 3480–84
14. Drennan MB, Nicolle D, Quesniaux VJ et al: Toll-like receptor 2-deficient mice succumb to Mycobacterium tuberculosis infection. Am J Pathol, 2004; 164: 49–57
15. Sugawara I, Yamada H, Li C et al: Mycobacterial infection in TLR2 and TLR6 knockout mice. Microbiol Immunol, 2003; 47: 327–36
16. Abel B, Thieblemont N, Quesniaux VJ et al: Toll-like receptor 4 expression is required to control chronic Mycobacterium tuberculosis infection in mice. J Immunol, 2002; 169: 3155–62
17. Bafica A, Scanga CA, Feng CG et al: TLR9 regulates Th1 responses and cooperates with TLR2 in mediating optimal resistance to Mycobacterium tuberculosis. J Exp Med, 2005; 202: 1715–24
18. Wells G, Shea B, O’Connell D et al: The Newcastle-Ottawa Scale (NOS) for assessing the quality of nonrandomized studies in meta-analyses. http://www.ohri.ca/program/clinical_epidemiology/oxford.htm
19. DerSimonian R, Laird N: Meta-analysis in clinical trials. Control Clin Trials, 1986; 7: 177–88
20. Begg CB, Mazumdar M: Operating characteristics of a rank correlation test for publication bias. Biometrics, 1994; 50: 1088–101
21. Egger M, Davey Smith G, Schneider M, Minder C: Bias in meta-analysis detected by a simple, graphical test. BMJ, 1997; 315: 629–34
22. Lee PL, West C, Crain K, Wang L: Genetic polymorphisms and susceptibility to lung disease. J Negat Results Biomed, 2006; 5: 5
23. Collins RL, Hu T, Wejse C et al: Multifactor dimensionality reduction reveals a three-locus epistatic interaction associated with susceptibility to pulmonary tuberculosis. BioData Min, 2013; 6: 4
24. Velez DR, Hulme WF, Myers JL et al: NOS2A, TLR4, and IFNGR1 interactions influence pulmonary tuberculosis susceptibility in African-Americans. Hum Genet, 2009; 126: 643–53
25. Arji N, Busson M, Iraqi G et al: Genetic diversity of TLR2, TLR4, and VDR loci and pulmonary tuberculosis in Moroccan patients. J Infect Dev Ctries, 2014; 8: 430–40
26. Zaki HY, Leung KH, Yiu WC et al: Common polymorphisms in TLR4 gene associated with susceptibility to pulmonary tuberculosis in the Sudanese. Int J Tuberc Lung Dis, 2012; 16: 934–40
27. Velez DR, Wejse C, Stryjewski ME et al: Variants in toll-like receptors 2 and 9 influence susceptibility to pulmonary tuberculosis in Caucasians, African- Americans, and West Africans. Hum Genet, 2010; 127: 65–73
28. Bharti D, Kumar A, Mahla RS et al: The role of TLR9 polymorphism in susceptibility to pulmonary tuberculosis. Immunogenetics, 2014; 66(12): 675–81
29. Xue Y, Zhao ZQ, Wang HJ et al: Toll-like receptors 2 and 4 gene polymorphisms in a southeastern Chinese population with tuberculosis. Int J Immunogenet, 2010; 37: 135–38
30. Ferwerda B, Kibiki GS, Netea MG et al: The toll-like receptor 4 Asp299Gly variant and tuberculosis susceptibility in HIV-infected patients in Tanzania. AIDS, 2007; 21: 1375–77
31. Pulido I, Leal M, Genebat M et al: The TLR4 ASP299GLY polymorphism is a risk factor for active tuberculosis in Caucasian HIV-infected patients. Curr HIV Res, 2010; 8: 253–58
32. Kobayashi K, Yuliwulandari R, Yanai H et al: Association of TLR polymorphisms with development of tuberculosis in Indonesian females. Tissue Antigens, 2012; 79: 190–97
33. Olesen R, Wejse C, Velez DR et al: DC-SIGN (CD209), pentraxin 3 and vitamin D receptor gene variants associate with pulmonary tuberculosis risk in West Africans. Genes Immun, 2007; 8: 456–67
34. Selvaraj P, Harishankar M, Singh B et al: Toll-like receptor and TIRAP gene polymorphisms in pulmonary tuberculosis patients of South India. Tuberculosis (Edinb), 2010; 90: 306–10
35. Torres-Garcia D, Cruz-Lagunas A, Garcia-Sancho Figueroa MC et al: Variants in toll-like receptor 9 gene influence susceptibility to tuberculosis in a Mexican population. J Transl Med, 2013; 11: 220
36. Yang Y, Li X, Cui W et al: Potential association of pulmonary tuberculosis with genetic polymorphisms of toll-like receptor 9 and interferon-gamma in a Chinese population. BMC Infect Dis, 2013; 13: 511
37. Jahantigh D, Salimi S, Alavi-Naini R et al; Association between TLR4 and TLR9 gene polymorphisms with development of pulmonary tuberculosis in Zahedan, southeastern Iran. ScientificWorldJournal, 2013; 2013: 534053
38. Sanchez D, Lefebvre C, Rioux J et al: Evaluation of Toll-like receptor and adaptor molecule polymorphisms for susceptibility to tuberculosis in a Colombian population. Int J Immunogenet, 2012; 39: 216–23
39. Ma X, Liu Y, Gowen BB et al: Full-exon resequencing reveals toll-like receptor variants contribute to human susceptibility to tuberculosis disease. PLoS One, 2007; 2: e1318
40. Najmi N, Kaur G, Sharma SK, Mehra NK: Human Toll-like receptor 4 polymorphisms TLR4 Asp299Gly and Thr399Ile influence susceptibility and severity of pulmonary tuberculosis in the Asian Indian population. Tissue Antigens, 2010; 76: 102–9
41. Newport MJ, Allen A, Awomoyi AA et al: The toll-like receptor 4 Asp299Gly variant: no influence on LPS responsiveness or susceptibility to pulmonary tuberculosis in The Gambia. Tuberculosis (Edinb), 2004; 84: 347–52
42. Rosas-Taraco AG, Revol A, Salinas-Carmona MC et al: CD14 C(-159)T polymorphism is a risk factor for development of pulmonary tuberculosis. J Infect Dis, 2007; 196: 1698–706
43. Fitness J, Floyd S, Warndorff DK et al: Large-scale candidate gene study of tuberculosis susceptibility in the Karonga district of northern Malawi. Am J Trop Med Hyg, 2004; 71: 341–49
44. Krieg AM: CpG motifs in bacterial DNA and their immune effects. Annu Rev Immunol, 2002; 20: 709–60
45. Lazarus R, Klimecki WT, Raby BA et al: Single-nucleotide polymorphisms in the Toll-like receptor 9 gene (TLR9): frequencies, pairwise linkage disequilibrium, and haplotypes in three U.S. ethnic groups and exploratory casecontrol disease association studies. Genomics, 2003; 81: 85–91
46. Thye T, Vannberg FO, Wong SH et al: Genome-wide association analyses identifies a susceptibility locus for tuberculosis on chromosome 18q11. 2. Nat Genet, 2010; 42: 739–41
47. Png E, Alisjahbana B, Sahiratmadja E et al: A genome wide association study of pulmonary tuberculosis susceptibility in Indonesians. BMC Med Genet, 2012; 13: 5