Human pancreatic cancer stem cells are sensitive to dual inhibition of IGF-IR and ErbB receptors

BMC Cancer

Volumn 15, Issue 1, 2015, Pages

  Urtasun, Nerea ^a   Vidal Pla, Anna ^a   Pérez Torras, Sandra ^a,b   Mazo, Adela ^a,b  

^a UNIVERSITY OF BARCELONA   (Spain)

^b INSTITUTO DE SALUD CARLOS III   (Spain)

Author keywords

Cancer stem cells; EGFR; Her 2; IGF IR; Pancreatic ductal adenocarcinoma

Indexed keywords

EPIDERMAL GROWTH FACTOR RECEPTOR 2; GEMCITABINE; INSULIN RECEPTOR SUBSTRATE 1; LAPATINIB; MITOGEN ACTIVATED PROTEIN KINASE; NVP AEW 541; PROTEIN KINASE B; SOMATOMEDIN C RECEPTOR; ANTINEOPLASTIC AGENT; EPIDERMAL GROWTH FACTOR RECEPTOR; PROTEIN KINASE INHIBITOR; QUINAZOLINE DERIVATIVE;

ARTICLE; CANCER RESISTANCE; CANCER STEM CELL; CELL VIABILITY; CHEMOSENSITIVITY; CONTROLLED STUDY; HUMAN; HUMAN CELL; INHIBITION KINETICS; MOLECULAR INTERACTION; MTT ASSAY; PANCREATIC CANCER CELL LINE; SENSITIVITY ANALYSIS; SIGNAL TRANSDUCTION; WESTERN BLOTTING; WST-8 ASSAY; ANTAGONISTS AND INHIBITORS; CELL PROLIFERATION; CELL SURVIVAL; DRUG EFFECTS; DRUG RESISTANCE; METABOLISM; MULTICELLULAR SPHEROID; PANCREAS TUMOR; TUMOR CELL CULTURE; TUMOR CELL LINE;

ANTINEOPLASTIC AGENTS; CELL LINE, TUMOR; CELL PROLIFERATION; CELL SURVIVAL; DRUG RESISTANCE, NEOPLASM; ERBB RECEPTORS; HUMANS; NEOPLASTIC STEM CELLS; PANCREATIC NEOPLASMS; PROTEIN KINASE INHIBITORS; QUINAZOLINES; RECEPTOR, IGF TYPE 1; SIGNAL TRANSDUCTION; SPHEROIDS, CELLULAR; TUMOR CELLS, CULTURED;

EID: 84928155261     PISSN: None     EISSN: 14712407     Source Type: Journal    
DOI: 10.1186/s12885-015-1249-2     Document Type: Article

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