Effects of silver nanoparticles and gold nanoparticles on IL-2, IL-6, and TNF-α production via MAPK pathway in leukemic cell lines

Genetics and Molecular Research

Volumn 14, Issue 2, 2015, Pages 3650-3668

  Parnsamut, C ^a   Brimson, S ^a  

^a CHULALONGKORN UNIVERSITY   (Thailand)

Author keywords

C Jun N terminal kinase; Cytokines; Extracellular receptor kinase; Jurkat; Silver gold nanoparticles; U937

Indexed keywords

GOLD NANOPARTICLE; INTERLEUKIN 2; INTERLEUKIN 6; MITOGEN ACTIVATED PROTEIN KINASE; SILVER NANOPARTICLE; STRESS ACTIVATED PROTEIN KINASE; TUMOR NECROSIS FACTOR ALPHA; GOLD; LIPOPOLYSACCHARIDE; METAL NANOPARTICLE; PHORBOL 13 ACETATE 12 MYRISTATE; PHYTOHEMAGGLUTININ; SILVER; TUMOR NECROSIS FACTOR;

ANTINEOPLASTIC ACTIVITY; ANTIPROLIFERATIVE ACTIVITY; ARTICLE; CELL PROLIFERATION; CELL VIABILITY; CONCENTRATION RESPONSE; CONTROLLED STUDY; CYTOKINE PRODUCTION; CYTOKINE RELEASE; DRUG EFFECT; DRUG RESPONSE; ENZYME ACTIVATION; ENZYME ACTIVITY; HUMAN; HUMAN CELL; LEUKEMIA CELL LINE; MONOCYTIC LEUKEMIA; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; T CELL LEUKEMIA; BIOSYNTHESIS; CELL SURVIVAL; CHEMISTRY; DOSE RESPONSE; DRUG EFFECTS; ENZYME LINKED IMMUNOSORBENT ASSAY; JURKAT CELL LINE; LEUKEMIA; METABOLISM; PATHOLOGY; U937 CELL LINE; WESTERN BLOTTING;

BLOTTING, WESTERN; CELL PROLIFERATION; CELL SURVIVAL; DOSE-RESPONSE RELATIONSHIP, DRUG; ENZYME ACTIVATION; ENZYME-LINKED IMMUNOSORBENT ASSAY; GOLD; HUMANS; INTERLEUKIN-2; INTERLEUKIN-6; JURKAT CELLS; LEUKEMIA; LIPOPOLYSACCHARIDES; MAP KINASE SIGNALING SYSTEM; METAL NANOPARTICLES; MITOGEN-ACTIVATED PROTEIN KINASES; PHYTOHEMAGGLUTININS; SILVER; TETRADECANOYLPHORBOL ACETATE; TUMOR NECROSIS FACTOR-ALPHA; U937 CELLS;

EID: 84928125492     PISSN: None     EISSN: 16765680     Source Type: Journal    
DOI: 10.4238/2015.April.17.15     Document Type: Article

References (34)

1. Alarcon EI, Udekwu K, Skog M, Pacioni NL, et al. (2012). The biocompatibility and antibacterial properties of collagen-stabilized, photochemically prepared silver nanoparticles. Biomaterials 33: 4947-4956.
2. Arvizo RR, Rana S, Miranda OR, Bhattacharya R, et al. (2011). Mechanism of anti-angiogenic property of gold nanoparticles: role of nanoparticle size and surface charge. Nanomedicine 7: 580-587.
3. Bhattacharya R, Patra CR, Verma R and Kumar S (2007). Gold nanoparticles inhibit the proliferation of multiple myeloma cells. Adv. Mater. 19: 711-716.
4. Bogumila R, Andrea H, Andreas L and Kenneth AD (2013). Mechanisms of silver nanoparticle release, transformation and toxicity: A critical review of current knowledge and recommendations for future studies and applications. Materials 6: 2295-2350.
5. Bradley JR (2008). TNF-mediated inflammatory disease. J. Pathol. 214: 149-160.
6. Brown G, Hughes PJ, Ceredig R and Michell RH (2012). Versatility and nuances of the architecture of haematopoiesis - Implications for the nature of leukaemia. Leuk. Res. 36: 14-22.
7. Bubici C, Papa S, Pham CG, Zazzeroni F, et al. (2004). NF-kappaB and JNK: an intricate affair. Cell Cycle 3: 1524-1529.
8. Chang L and Karin M (2001). Mammalian MAP kinase signalling cascades. Nature 410: 37-40.
9. Choi SY, Jeong S, Jang SH, Park J, et al. (2012). In vitro toxicity of serum protein-adsorbed citrate-reduced gold nanoparticles in human lung adenocarcinoma cells. Toxicol. In Vitro 26: 229-237.
10. Comfort KK, Maurer EI, Braydich-Stolle LK and Hussain SM (2011). Interference of silver, gold, and iron oxide nanoparticles on epidermal growth factor signal transduction in epithelial cells. ACS Nano 5: 10000-10008.
11. de Haij S, Bakker AC, van der Geest RN, Haegeman G, et al. (2005). NF-kappaB mediated IL-6 production by renal epithelial cells is regulated by c-jun NH2-terminal kinase. J. Am. Soc. Nephrol. 16: 1603-1611.
12. Dhillon AS, Hagan S, Rath O and Kolch W (2007). MAP kinase signalling pathways in cancer. Oncogene 26: 3279-3290.
13. Eom HJ and Choi J (2010). p38 MAPK activation, DNA damage, cell cycle arrest and apoptosis as mechanisms of toxicity of silver nanoparticles in Jurkat T cells. Environ. Sci. Technol. 44: 8337-8342.
14. Eustis S (2006). Gold and Silver Nanoparticles: Characterization of Their Interesting Optical Properties and the Mechanism of Their Photochemical Formation. Doctoral thesis, Department of Chemistry and Biology Georgia Institute of Technology. Atlanta, 290.
15. Gaffen SL (2001). Signaling domains of the interleukin 2 receptor. Cytokine 14: 63-77.
16. Guo D, Zhu L, Huang Z, Zhou H, et al. (2013). Anti-leukemia activity of PVP-coated silver nanoparticles via generation of reactive oxygen species and release of silver ions. Biomaterials 34: 7884-7894.
17. Hsin YH, Chen CF, Huang S, Shih TS, et al. (2008). The apoptotic effect of nanosilver is mediated by a ROS- and JNK-dependent mechanism involving the mitochondrial pathway in NIH3T3 cells. Toxicol. Lett. 179: 130-139.
18. Kennedy NJ, Sluss HK, Jones SN, Bar-Sagi D, et al. (2003). Suppression of Ras-stimulated transformation by the JNK signal transduction pathway. Genes Dev. 17: 629-637.
19. Khan HA, Abdelhalim MA, Alhomida AS and Al-Ayed MS (2013). Effects of naked gold nanoparticles on proinflammatory cytokines mRNA expression in rat liver and kidney. Biomed. Res. Int. 590730.
20. Kim S, Choi JE, Choi J, Chung KH, et al. (2009). Oxidative stress-dependent toxicity of silver nanoparticles in human hepatoma cells. Toxicol. In Vitro 23: 1076-1084.
21. Kyriakis JM and Avruch J (2001). Mammalian mitogen-activated protein kinase signal transduction pathways activated by stress and inflammation. Physiol. Rev. 81: 807-869.
22. Lim D, Roh JY, Eom HJ, Choi JY, et al. (2012). Oxidative stress-related PMK-1 P38 MAPK activation as a mechanism for toxicity of silver nanoparticles to reproduction in the nematode Caenorhabditis elegans. Environ. Toxicol. Chem. 31: 585-592.
23. Marques-Fernandez F, Planells-Ferrer L, Gozzelino R, Galenkamp KM, et al. (2013). TNFα induces survival through the FLIP-L-dependent activation of the MAPK/ERK pathway. Cell Death. Dis. 4: e493.
24. O’Shea JJ, Tato CM and Siegel R (2008). Principles of Immune Recognition: Cytokines and Cytokine Receptors. In: Clinical Immunology. 3rd edn. (Rich RR, Shearer WT, Fleischer TA, Schroeder HW, et al., eds.). Elsevier, Amsterdam.
25. Panácek A, Kolár M, Vecerová R, Prucek R, et al. (2009). Antifungal activity of silver nanoparticles against Candida spp. Biomaterials 30: 6333-6340.
26. Piller G (1993). The history of leukemia: a personal perspective. Blood Cells 19: 521-529.
27. Platanias LC (2003). Map kinase signaling pathways and hematologic malignancies. Blood 101: 4667-4679.
28. Solomon SD, Bahadory M, Jeyarajasingam AV and Rutkowsky SA (2007). Synthesis and study of silver nanoparticles. J. Chem. Educ. 84: 322.
29. Turkevich J, Stevenson PC and Hillier J (1951). A study of the nucleation and growth processes in the synthesis of colloidal gold. Discuss. Faraday Soc. 11: 55-75.
30. Wang H, Qiao X, Chen J and Wang X (2005). Mechanisms of PVP in the preparation of silver nanoparticles. Mater. Chem. Phys. 94: 449-453.
31. Wong KK, Cheung SO, Huang L, Niu J, et al. (2009). Further evidence of the anti-inflammatory effects of silver nanoparticles. Chem. Med. Chem. 4: 1129-1135.
32. Yen HJ, Hsu SH and Tsai CL (2009). Cytotoxicity and immunological response of gold and silver nanoparticles of different sizes. Small 5: 1553-1561.
33. Yi C, Liu D, Fong CC and Zhang J, et al. (2010). Gold nanoparticles promote osteogenic differentiation of mesenchymal stem cells through p38 MAPK pathway. ACS Nano 4: 6439-6448.
34. Zhou GQ and Wang WY (2012). Synthesis of silver nanoparticles and their antiproliferation against human lung cancer cells in vitro. Orient. J. Chem. 28: 651.