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Volumn 21, Issue 5, 2015, Pages 934-940

Bone marrow mesenchymal stromal cells from patients with acute and chronic graft-versus-host disease deploy normal phenotype, differentiation plasticity, and immune-suppressive activity

Author keywords

Autologous; GVHD; Immunosuppression; MSC; Tolerance

Indexed keywords

GAMMA INTERFERON; INDOLEAMINE 2,3 DIOXYGENASE;

EID: 84928124689     PISSN: 10838791     EISSN: 15236536     Source Type: Journal    
DOI: 10.1016/j.bbmt.2015.01.014     Document Type: Article
Times cited : (35)

References (52)
  • 1
    • 0034564569 scopus 로고    scopus 로고
    • Arandomized trial comparing prednisone with antithymocyte globulin/prednisone as an initial systemic therapy for moderately severe acute graft-versus-host disease
    • Cragg L., Blazar B.R., Defor T., et al. Arandomized trial comparing prednisone with antithymocyte globulin/prednisone as an initial systemic therapy for moderately severe acute graft-versus-host disease. Biol Blood Marrow Transplant 2000, 6:441-447.
    • (2000) Biol Blood Marrow Transplant , vol.6 , pp. 441-447
    • Cragg, L.1    Blazar, B.R.2    Defor, T.3
  • 2
    • 52949086615 scopus 로고    scopus 로고
    • Novel drugs for the prevention and treatment of acute GVHD
    • Cutler C., Antin J.H. Novel drugs for the prevention and treatment of acute GVHD. Curr Pharm Des 2008, 14:1962-1973.
    • (2008) Curr Pharm Des , vol.14 , pp. 1962-1973
    • Cutler, C.1    Antin, J.H.2
  • 3
    • 4444304402 scopus 로고    scopus 로고
    • Effect of up-front daclizumab when combined with steroids for the treatment of acute graft-versus-host disease: results of a randomized trial
    • Lee S.J., Zahrieh D., Agura E., et al. Effect of up-front daclizumab when combined with steroids for the treatment of acute graft-versus-host disease: results of a randomized trial. Blood 2004, 104:1559-1564.
    • (2004) Blood , vol.104 , pp. 1559-1564
    • Lee, S.J.1    Zahrieh, D.2    Agura, E.3
  • 4
    • 33947253595 scopus 로고    scopus 로고
    • Aphase 2/3 multicenter randomized clinical trial of ABX-CBL versus ATG as secondary therapy for steroid-resistant acute graft-versus-host disease
    • Macmillan M.L., Couriel D., Weisdorf D.J., et al. Aphase 2/3 multicenter randomized clinical trial of ABX-CBL versus ATG as secondary therapy for steroid-resistant acute graft-versus-host disease. Blood 2007, 109:2657-2662.
    • (2007) Blood , vol.109 , pp. 2657-2662
    • Macmillan, M.L.1    Couriel, D.2    Weisdorf, D.J.3
  • 6
    • 26944492726 scopus 로고    scopus 로고
    • Chronic graft-versus-host disease: where is promise for the future?
    • Weisdorf D.J. Chronic graft-versus-host disease: where is promise for the future?. Leukemia 2005, 19:1532-1535.
    • (2005) Leukemia , vol.19 , pp. 1532-1535
    • Weisdorf, D.J.1
  • 7
    • 84881260492 scopus 로고    scopus 로고
    • Mechanisms of immune modulation by mesenchymal stromal cells and clinical translation
    • Stagg J., Galipeau J. Mechanisms of immune modulation by mesenchymal stromal cells and clinical translation. Curr Mol Med 2013, 13:856-867.
    • (2013) Curr Mol Med , vol.13 , pp. 856-867
    • Stagg, J.1    Galipeau, J.2
  • 8
    • 84896710813 scopus 로고    scopus 로고
    • Treatment of graft versus host disease with mesenchymal stromal cells: a phase I study on 40 adult and pediatric patients
    • Introna M., Lucchini G., Dander E., et al. Treatment of graft versus host disease with mesenchymal stromal cells: a phase I study on 40 adult and pediatric patients. Biol Blood Marrow Transplant 2014, 20:375-381.
    • (2014) Biol Blood Marrow Transplant , vol.20 , pp. 375-381
    • Introna, M.1    Lucchini, G.2    Dander, E.3
  • 9
    • 43049103438 scopus 로고    scopus 로고
    • Mesenchymal stem cells for treatment of steroid-resistant, severe, acute graft-versus-host disease: a phase II study
    • Le Blanc K., Frassoni F., Ball L., et al. Mesenchymal stem cells for treatment of steroid-resistant, severe, acute graft-versus-host disease: a phase II study. Lancet 2008, 371:1579-1586.
    • (2008) Lancet , vol.371 , pp. 1579-1586
    • Le Blanc, K.1    Frassoni, F.2    Ball, L.3
  • 10
    • 2342482526 scopus 로고    scopus 로고
    • Treatment of severe acute graft-versus-host disease with third party haploidentical mesenchymal stem cells
    • Le Blanc K., Rasmusson I., Sundberg B., et al. Treatment of severe acute graft-versus-host disease with third party haploidentical mesenchymal stem cells. Lancet 2004, 363:1439-1441.
    • (2004) Lancet , vol.363 , pp. 1439-1441
    • Le Blanc, K.1    Rasmusson, I.2    Sundberg, B.3
  • 11
    • 77955509074 scopus 로고    scopus 로고
    • Platelet-lysate-expanded mesenchymal stromal cells as a salvage therapy for severe resistant graft-versus-host disease in a pediatric population
    • Lucchini G., Introna M., Dander E., et al. Platelet-lysate-expanded mesenchymal stromal cells as a salvage therapy for severe resistant graft-versus-host disease in a pediatric population. Biol Blood Marrow Transplant 2010, 16:1293-1301.
    • (2010) Biol Blood Marrow Transplant , vol.16 , pp. 1293-1301
    • Lucchini, G.1    Introna, M.2    Dander, E.3
  • 12
    • 33744913533 scopus 로고    scopus 로고
    • Mesenchymal stem cells for treatment of therapy-resistant graft-versus-host disease
    • Ringden O., Uzunel M., Rasmusson I., et al. Mesenchymal stem cells for treatment of therapy-resistant graft-versus-host disease. Transplantation 2006, 81:1390-1397.
    • (2006) Transplantation , vol.81 , pp. 1390-1397
    • Ringden, O.1    Uzunel, M.2    Rasmusson, I.3
  • 13
    • 60349129494 scopus 로고    scopus 로고
    • Treatment of refractory acute GVHD with third-party MSC expanded in platelet lysate-containing medium
    • von Bonin M., Stolzel F., Goedecke A., et al. Treatment of refractory acute GVHD with third-party MSC expanded in platelet lysate-containing medium. Bone Marrow Transplant 2009, 43:245-251.
    • (2009) Bone Marrow Transplant , vol.43 , pp. 245-251
    • von Bonin, M.1    Stolzel, F.2    Goedecke, A.3
  • 14
    • 84875468183 scopus 로고    scopus 로고
    • The mesenchymal stromal cells dilemma-does a negative phase III trial of random donor mesenchymal stromal cells in steroid-resistant graft-versus-host disease represent a death knell or a bump in the road?
    • Galipeau J. The mesenchymal stromal cells dilemma-does a negative phase III trial of random donor mesenchymal stromal cells in steroid-resistant graft-versus-host disease represent a death knell or a bump in the road?. Cytotherapy 2013, 15:2-8.
    • (2013) Cytotherapy , vol.15 , pp. 2-8
    • Galipeau, J.1
  • 15
    • 28844483809 scopus 로고    scopus 로고
    • Allogeneic marrow stromal cells are immune rejected by MHC class I- and class II-mismatched recipient mice
    • Eliopoulos N., Stagg J., Lejeune L., et al. Allogeneic marrow stromal cells are immune rejected by MHC class I- and class II-mismatched recipient mice. Blood 2005, 106:4057-4065.
    • (2005) Blood , vol.106 , pp. 4057-4065
    • Eliopoulos, N.1    Stagg, J.2    Lejeune, L.3
  • 16
    • 84900335160 scopus 로고    scopus 로고
    • Allo-reactivity of mesenchymal stem cells in rhesus macaques is dose and haplotype dependent and limits durable cell engraftment invivo
    • Isakova I.A., Lanclos C., Bruhn J., et al. Allo-reactivity of mesenchymal stem cells in rhesus macaques is dose and haplotype dependent and limits durable cell engraftment invivo. PLoS One 2014, 9:e87238.
    • (2014) PLoS One , vol.9 , pp. e87238
    • Isakova, I.A.1    Lanclos, C.2    Bruhn, J.3
  • 17
    • 33746514768 scopus 로고    scopus 로고
    • Donor-derived mesenchymal stem cells are immunogenic in an allogeneic host and stimulate donor graft rejection in a nonmyeloablative setting
    • Nauta A.J., Westerhuis G., Kruisselbrink A.B., et al. Donor-derived mesenchymal stem cells are immunogenic in an allogeneic host and stimulate donor graft rejection in a nonmyeloablative setting. Blood 2006, 108:2114-2120.
    • (2006) Blood , vol.108 , pp. 2114-2120
    • Nauta, A.J.1    Westerhuis, G.2    Kruisselbrink, A.B.3
  • 18
    • 0028881201 scopus 로고
    • Exvivo expansion and subsequent infusion of human bone marrow-derived stromal progenitor cells (mesenchymal progenitor cells): implications for therapeutic use
    • Lazarus H.M., Haynesworth S.E., Gerson S.L., et al. Exvivo expansion and subsequent infusion of human bone marrow-derived stromal progenitor cells (mesenchymal progenitor cells): implications for therapeutic use. Bone Marrow Transplant 1995, 16:557-564.
    • (1995) Bone Marrow Transplant , vol.16 , pp. 557-564
    • Lazarus, H.M.1    Haynesworth, S.E.2    Gerson, S.L.3
  • 19
    • 43549102915 scopus 로고    scopus 로고
    • Properties and potential of bone marrow mesenchymal stromal cells from children with hematologic diseases
    • Dimitriou H., Linardakis E., Martimianaki G., et al. Properties and potential of bone marrow mesenchymal stromal cells from children with hematologic diseases. Cytotherapy 2008, 10:125-133.
    • (2008) Cytotherapy , vol.10 , pp. 125-133
    • Dimitriou, H.1    Linardakis, E.2    Martimianaki, G.3
  • 20
    • 34548512229 scopus 로고    scopus 로고
    • Phenotypic and functional comparison of mesenchymal stem cells derived from the bone marrow of normal adults and patients with hematologic malignant diseases
    • Zhao Z.G., Liang Y., Li K., et al. Phenotypic and functional comparison of mesenchymal stem cells derived from the bone marrow of normal adults and patients with hematologic malignant diseases. Stem Cells Dev 2007, 16:637-648.
    • (2007) Stem Cells Dev , vol.16 , pp. 637-648
    • Zhao, Z.G.1    Liang, Y.2    Li, K.3
  • 21
    • 84875329801 scopus 로고    scopus 로고
    • Evidences of early senescence in multiple myeloma bone marrow mesenchymal stromal cells
    • Andre T., Meuleman N., Stamatopoulos B., et al. Evidences of early senescence in multiple myeloma bone marrow mesenchymal stromal cells. PLoS One 2013, 8:e59756.
    • (2013) PLoS One , vol.8 , pp. e59756
    • Andre, T.1    Meuleman, N.2    Stamatopoulos, B.3
  • 22
    • 84881026080 scopus 로고    scopus 로고
    • The effect of platelet lysate fibrinogen on the functionality of MSCs in immunotherapy
    • Copland I.B., Garcia M.A., Waller E.K., et al. The effect of platelet lysate fibrinogen on the functionality of MSCs in immunotherapy. Biomaterials 2013, 34:7840-7850.
    • (2013) Biomaterials , vol.34 , pp. 7840-7850
    • Copland, I.B.1    Garcia, M.A.2    Waller, E.K.3
  • 23
    • 34548630221 scopus 로고    scopus 로고
    • Regulation of MHC class II expression and antigen processing in murine and human mesenchymal stromal cells by IFN-gamma, TGF-beta, and cell density
    • Romieu-Mourez R., Francois M., Boivin M.N., et al. Regulation of MHC class II expression and antigen processing in murine and human mesenchymal stromal cells by IFN-gamma, TGF-beta, and cell density. JImmunol 2007, 179:1549-1558.
    • (2007) JImmunol , vol.179 , pp. 1549-1558
    • Romieu-Mourez, R.1    Francois, M.2    Boivin, M.N.3
  • 24
    • 67649209791 scopus 로고    scopus 로고
    • Cytokine modulation of TLR expression and activation in mesenchymal stromal cells leads to a proinflammatory phenotype
    • Romieu-Mourez R., Francois M., Boivin M.N., et al. Cytokine modulation of TLR expression and activation in mesenchymal stromal cells leads to a proinflammatory phenotype. JImmunol 2009, 182:7963-7973.
    • (2009) JImmunol , vol.182 , pp. 7963-7973
    • Romieu-Mourez, R.1    Francois, M.2    Boivin, M.N.3
  • 25
    • 0038725131 scopus 로고    scopus 로고
    • Allele frequencies for 15 autosomal STR loci on U.S. Caucasian, African American, and Hispanic populations
    • Butler J.M., Schoske R., Vallone P.M., et al. Allele frequencies for 15 autosomal STR loci on U.S. Caucasian, African American, and Hispanic populations. JForensic Sci 2003, 48:908-911.
    • (2003) JForensic Sci , vol.48 , pp. 908-911
    • Butler, J.M.1    Schoske, R.2    Vallone, P.M.3
  • 26
    • 59649091248 scopus 로고    scopus 로고
    • Mesenchymal stem cells remain host-derived independent of the source of the stem-cell graft and conditioning regimen used
    • Bartsch K., Al-Ali H., Reinhardt A., et al. Mesenchymal stem cells remain host-derived independent of the source of the stem-cell graft and conditioning regimen used. Transplantation 2009, 87:217-221.
    • (2009) Transplantation , vol.87 , pp. 217-221
    • Bartsch, K.1    Al-Ali, H.2    Reinhardt, A.3
  • 27
    • 20944450977 scopus 로고    scopus 로고
    • Mesenchymal stem cells remain of host origin even a long time after allogeneic peripheral blood stem cell or bone marrow transplantation
    • Rieger K., Marinets O., Fietz T., et al. Mesenchymal stem cells remain of host origin even a long time after allogeneic peripheral blood stem cell or bone marrow transplantation. Exp Hematol 2005, 33:605-611.
    • (2005) Exp Hematol , vol.33 , pp. 605-611
    • Rieger, K.1    Marinets, O.2    Fietz, T.3
  • 28
    • 24144465111 scopus 로고    scopus 로고
    • Mesenchymal stem cells in stem cell transplant recipients are damaged and remain of host origin
    • Wang J., Liu K., Lu D.P. Mesenchymal stem cells in stem cell transplant recipients are damaged and remain of host origin. Int J Hematol 2005, 82:152-158.
    • (2005) Int J Hematol , vol.82 , pp. 152-158
    • Wang, J.1    Liu, K.2    Lu, D.P.3
  • 29
    • 33745215431 scopus 로고    scopus 로고
    • Donor multipotent mesenchymal stromal cells may engraft in pediatric patients given either cord blood or bone marrow transplantation
    • Pozzi S., Lisini D., Podesta M., et al. Donor multipotent mesenchymal stromal cells may engraft in pediatric patients given either cord blood or bone marrow transplantation. Exp Hematol 2006, 34:934-942.
    • (2006) Exp Hematol , vol.34 , pp. 934-942
    • Pozzi, S.1    Lisini, D.2    Podesta, M.3
  • 30
    • 10444265863 scopus 로고    scopus 로고
    • Mesenchymal stem cells are present in peripheral blood and can engraft after allogeneic hematopoietic stem cell transplantation
    • Villaron E.M., Almeida J., Lopez-Holgado N., et al. Mesenchymal stem cells are present in peripheral blood and can engraft after allogeneic hematopoietic stem cell transplantation. Haematologica 2004, 89:1421-1427.
    • (2004) Haematologica , vol.89 , pp. 1421-1427
    • Villaron, E.M.1    Almeida, J.2    Lopez-Holgado, N.3
  • 31
    • 84881092225 scopus 로고    scopus 로고
    • Immunological characterization of multipotent mesenchymal stromal cells-The International Society for Cellular Therapy (ISCT) working proposal
    • Krampera M., Galipeau J., Shi Y., et al. Immunological characterization of multipotent mesenchymal stromal cells-The International Society for Cellular Therapy (ISCT) working proposal. Cytotherapy 2013, 15:1054-1061.
    • (2013) Cytotherapy , vol.15 , pp. 1054-1061
    • Krampera, M.1    Galipeau, J.2    Shi, Y.3
  • 32
    • 84925482125 scopus 로고    scopus 로고
    • Immune impairments in multiple myeloma bone marrow mesenchymal stromal cells
    • Andre T., Najar M., Stamatopoulos B., et al. Immune impairments in multiple myeloma bone marrow mesenchymal stromal cells. Cancer Immunol Immunother 2015, 64:213-224.
    • (2015) Cancer Immunol Immunother , vol.64 , pp. 213-224
    • Andre, T.1    Najar, M.2    Stamatopoulos, B.3
  • 33
    • 0017190491 scopus 로고
    • Effects of radiation on hematopoietic stroma
    • Fried W., Chamberlin W., Kedo A., et al. Effects of radiation on hematopoietic stroma. Exp Hematol 1976, 4:310-314.
    • (1976) Exp Hematol , vol.4 , pp. 310-314
    • Fried, W.1    Chamberlin, W.2    Kedo, A.3
  • 34
    • 0032822268 scopus 로고    scopus 로고
    • Stromal damage as consequence of high-dose chemo/radiotherapy in bone marrow transplant recipients
    • Galotto M., Berisso G., Delfino L., et al. Stromal damage as consequence of high-dose chemo/radiotherapy in bone marrow transplant recipients. Exp Hematol 1999, 27:1460-1466.
    • (1999) Exp Hematol , vol.27 , pp. 1460-1466
    • Galotto, M.1    Berisso, G.2    Delfino, L.3
  • 35
    • 0346992206 scopus 로고    scopus 로고
    • Bone marrow stroma damage induced by chemotherapy for acute lymphoblastic leukemia in children
    • Corazza F., Hermans C., Ferster A., et al. Bone marrow stroma damage induced by chemotherapy for acute lymphoblastic leukemia in children. Pediatr Res 2004, 55:152-158.
    • (2004) Pediatr Res , vol.55 , pp. 152-158
    • Corazza, F.1    Hermans, C.2    Ferster, A.3
  • 36
    • 7944222582 scopus 로고    scopus 로고
    • Differential damage and recovery of human mesenchymal stem cells after exposure to chemotherapeutic agents
    • Li J., Law H.K., Lau Y.L., Chan G.C. Differential damage and recovery of human mesenchymal stem cells after exposure to chemotherapeutic agents. Br J Haematol 2004, 127:326-334.
    • (2004) Br J Haematol , vol.127 , pp. 326-334
    • Li, J.1    Law, H.K.2    Lau, Y.L.3    Chan, G.C.4
  • 37
    • 70349850496 scopus 로고    scopus 로고
    • Human alternatives to fetal bovine serum for the expansion of mesenchymal stromal cells from bone marrow
    • Bieback K., Hecker A., Kocaomer A., et al. Human alternatives to fetal bovine serum for the expansion of mesenchymal stromal cells from bone marrow. Stem Cells 2009, 27:2331-2341.
    • (2009) Stem Cells , vol.27 , pp. 2331-2341
    • Bieback, K.1    Hecker, A.2    Kocaomer, A.3
  • 38
    • 84887121126 scopus 로고    scopus 로고
    • Human platelet lysate stimulates high-passage and senescent human multipotent mesenchymal stromal cell growth and rejuvenation invitro
    • Griffiths S., Baraniak P.R., Copland I.B., et al. Human platelet lysate stimulates high-passage and senescent human multipotent mesenchymal stromal cell growth and rejuvenation invitro. Cytotherapy 2013, 15:1469-1483.
    • (2013) Cytotherapy , vol.15 , pp. 1469-1483
    • Griffiths, S.1    Baraniak, P.R.2    Copland, I.B.3
  • 39
    • 79960254998 scopus 로고    scopus 로고
    • Alkylating chemotherapeutic agents cyclophosphamide and melphalan cause functional injury to human bone marrow-derived mesenchymal stem cells
    • Kemp K., Morse R., Sanders K., et al. Alkylating chemotherapeutic agents cyclophosphamide and melphalan cause functional injury to human bone marrow-derived mesenchymal stem cells. Ann Hematol 2011, 90:777-789.
    • (2011) Ann Hematol , vol.90 , pp. 777-789
    • Kemp, K.1    Morse, R.2    Sanders, K.3
  • 40
    • 41649116836 scopus 로고    scopus 로고
    • Effects of adjuvant chemotherapy on bone marrow mesenchymal stem cells of colorectal cancer patients
    • Cao J., Tan M.H., Yang P., et al. Effects of adjuvant chemotherapy on bone marrow mesenchymal stem cells of colorectal cancer patients. Cancer Lett 2008, 263:197-203.
    • (2008) Cancer Lett , vol.263 , pp. 197-203
    • Cao, J.1    Tan, M.H.2    Yang, P.3
  • 41
    • 0031684999 scopus 로고    scopus 로고
    • Post-chemotherapy and cytokine pretreated marrow stromal cell layers suppress hematopoiesis from normal donor CD34+ cells
    • Schwartz G.N., Warren M.K., Rothwell S.W., et al. Post-chemotherapy and cytokine pretreated marrow stromal cell layers suppress hematopoiesis from normal donor CD34+ cells. Bone Marrow Transplant 1998, 22:457-468.
    • (1998) Bone Marrow Transplant , vol.22 , pp. 457-468
    • Schwartz, G.N.1    Warren, M.K.2    Rothwell, S.W.3
  • 42
    • 0030815188 scopus 로고    scopus 로고
    • Effect of chemotherapy for acute myelogenous leukemia on hematopoietic and fibroblast marrow progenitors
    • Carlo-Stella C., Tabilio A., Regazzi E., et al. Effect of chemotherapy for acute myelogenous leukemia on hematopoietic and fibroblast marrow progenitors. Bone Marrow Transplant 1997, 20:465-471.
    • (1997) Bone Marrow Transplant , vol.20 , pp. 465-471
    • Carlo-Stella, C.1    Tabilio, A.2    Regazzi, E.3
  • 43
    • 33845513318 scopus 로고    scopus 로고
    • Phenotypic and functional characterization of bone marrow mesenchymal stem cells derived from patients with multiple myeloma
    • Arnulf B., Lecourt S., Soulier J., et al. Phenotypic and functional characterization of bone marrow mesenchymal stem cells derived from patients with multiple myeloma. Leukemia 2007, 21:158-163.
    • (2007) Leukemia , vol.21 , pp. 158-163
    • Arnulf, B.1    Lecourt, S.2    Soulier, J.3
  • 44
    • 78650749445 scopus 로고    scopus 로고
    • Impairment in immunomodulatory function of mesenchymal stem cells from multiple myeloma patients
    • Li B., Fu J., Chen P., Zhuang W. Impairment in immunomodulatory function of mesenchymal stem cells from multiple myeloma patients. Arch Med Res 2010, 41:623-633.
    • (2010) Arch Med Res , vol.41 , pp. 623-633
    • Li, B.1    Fu, J.2    Chen, P.3    Zhuang, W.4
  • 45
    • 84856960632 scopus 로고    scopus 로고
    • Human MSC suppression correlates with cytokine induction of indoleamine 2,3-dioxygenase and bystander M2 macrophage differentiation
    • Francois M., Romieu-Mourez R., Li M., Galipeau J. Human MSC suppression correlates with cytokine induction of indoleamine 2,3-dioxygenase and bystander M2 macrophage differentiation. Mol Ther 2012, 20:187-195.
    • (2012) Mol Ther , vol.20 , pp. 187-195
    • Francois, M.1    Romieu-Mourez, R.2    Li, M.3    Galipeau, J.4
  • 46
    • 84866324411 scopus 로고    scopus 로고
    • Impact of lenalidomide on the functional properties of human mesenchymal stromal cells
    • Wobus M., Benath G., Ferrer R.A., et al. Impact of lenalidomide on the functional properties of human mesenchymal stromal cells. Exp Hematol 2012, 40:867-876.
    • (2012) Exp Hematol , vol.40 , pp. 867-876
    • Wobus, M.1    Benath, G.2    Ferrer, R.A.3
  • 47
    • 84883614526 scopus 로고    scopus 로고
    • Multipotent stromal cells induce human regulatory T cells through a novel pathway involving skewing of monocytes toward anti-inflammatory macrophages
    • Melief S.M., Schrama E., Brugman M.H., et al. Multipotent stromal cells induce human regulatory T cells through a novel pathway involving skewing of monocytes toward anti-inflammatory macrophages. Stem Cells 2013, 31:1980-1991.
    • (2013) Stem Cells , vol.31 , pp. 1980-1991
    • Melief, S.M.1    Schrama, E.2    Brugman, M.H.3
  • 48
    • 84883375670 scopus 로고    scopus 로고
    • Alterations in the cellular immune compartment of patients treated with third-party mesenchymal stromal cells following allogeneic hematopoietic stem cell transplantation
    • Jitschin R., Mougiakakos D., Von Bahr L., et al. Alterations in the cellular immune compartment of patients treated with third-party mesenchymal stromal cells following allogeneic hematopoietic stem cell transplantation. Stem Cells 2013, 31:1715-1725.
    • (2013) Stem Cells , vol.31 , pp. 1715-1725
    • Jitschin, R.1    Mougiakakos, D.2    Von Bahr, L.3
  • 49
    • 77954957825 scopus 로고    scopus 로고
    • Advancement of mesenchymal stem cell therapy in solid organ transplantation (MISOT)
    • Hoogduijn M.J., Popp F.C., Grohnert A., et al. Advancement of mesenchymal stem cell therapy in solid organ transplantation (MISOT). Transplantation 2010, 90:124-126.
    • (2010) Transplantation , vol.90 , pp. 124-126
    • Hoogduijn, M.J.1    Popp, F.C.2    Grohnert, A.3
  • 50
    • 84863632604 scopus 로고    scopus 로고
    • Ethylenecarbodiimide-fixed donor splenocyte infusions differentially target direct and indirect pathways of allorecognition for induction of transplant tolerance
    • Kheradmand T., Wang S., Bryant J., et al. Ethylenecarbodiimide-fixed donor splenocyte infusions differentially target direct and indirect pathways of allorecognition for induction of transplant tolerance. JImmunol 2012, 189:804-812.
    • (2012) JImmunol , vol.189 , pp. 804-812
    • Kheradmand, T.1    Wang, S.2    Bryant, J.3
  • 51
    • 33846919872 scopus 로고    scopus 로고
    • Peripheral tolerance induction using ethylenecarbodiimide-fixed APCs uses both direct and indirect mechanisms of antigen presentation for prevention of experimentalautoimmune encephalomyelitis
    • Turley D.M., Miller S.D. Peripheral tolerance induction using ethylenecarbodiimide-fixed APCs uses both direct and indirect mechanisms of antigen presentation for prevention of experimentalautoimmune encephalomyelitis. JImmunol 2007, 178:2212-2220.
    • (2007) JImmunol , vol.178 , pp. 2212-2220
    • Turley, D.M.1    Miller, S.D.2
  • 52
    • 84908637422 scopus 로고    scopus 로고
    • Single dose of autologous apoptotic cells preceding transplantation significantly enhances survival in lethal murine graft versus host models
    • Florek M., Sega E.I., Leveson-Gower D.B., et al. Single dose of autologous apoptotic cells preceding transplantation significantly enhances survival in lethal murine graft versus host models. Blood 2014, 124(11):1832-1842.
    • (2014) Blood , vol.124 , Issue.11 , pp. 1832-1842
    • Florek, M.1    Sega, E.I.2    Leveson-Gower, D.B.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.