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Volumn 8, Issue 3, 2013, Pages

Evidences of Early Senescence in Multiple Myeloma Bone Marrow Mesenchymal Stromal Cells

Author keywords

[No Author keywords available]

Indexed keywords

BETA GALACTOSIDASE; BORTEZOMIB; CHEMOKINE; CYTOKINE; LENALIDOMIDE; PROTEIN P21; PROTEIN P53; THALIDOMIDE;

EID: 84875329801     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0059756     Document Type: Article
Times cited : (85)

References (66)
  • 2
    • 79961027391 scopus 로고    scopus 로고
    • Treatment of multiple myeloma
    • Rajkumar SV, (2011) Treatment of multiple myeloma. Nat Rev Clin Oncol 8: 479-491.
    • (2011) Nat Rev Clin Oncol , vol.8 , pp. 479-491
    • Rajkumar, S.V.1
  • 7
    • 51649109321 scopus 로고    scopus 로고
    • Pathogenesis and progression of monoclonal gammopathy of undetermined significance
    • Blade J, Rosinol L, Cibeira MT, de Larrea CF, (2008) Pathogenesis and progression of monoclonal gammopathy of undetermined significance. Leukemia 22: 1651-1657.
    • (2008) Leukemia , vol.22 , pp. 1651-1657
    • Blade, J.1    Rosinol, L.2    Cibeira, M.T.3    de Larrea, C.F.4
  • 8
    • 0031048247 scopus 로고    scopus 로고
    • Risk of malignant transformation in patients with monoclonal gammopathy of undetermined significance
    • Pasqualetti P, Casale R, (1997) Risk of malignant transformation in patients with monoclonal gammopathy of undetermined significance. Biomed Pharmacother 51: 74-78.
    • (1997) Biomed Pharmacother , vol.51 , pp. 74-78
    • Pasqualetti, P.1    Casale, R.2
  • 9
    • 84857400014 scopus 로고    scopus 로고
    • Multiple myeloma
    • Brody H, (2011) Multiple myeloma. Nature 480: S33.
    • (2011) Nature , vol.480
    • Brody, H.1
  • 11
    • 34547106018 scopus 로고    scopus 로고
    • Understanding multiple myeloma pathogenesis in the bone marrow to identify new therapeutic targets
    • Hideshima T, Mitsiades C, Tonon G, Richardson PG, Anderson KC, (2007) Understanding multiple myeloma pathogenesis in the bone marrow to identify new therapeutic targets. Nat Rev Cancer 7: 585-598.
    • (2007) Nat Rev Cancer , vol.7 , pp. 585-598
    • Hideshima, T.1    Mitsiades, C.2    Tonon, G.3    Richardson, P.G.4    Anderson, K.C.5
  • 12
    • 42149142956 scopus 로고    scopus 로고
    • Unraveling the biology of multiple myeloma disease: cancer stem cells, acquired intracellular changes and interactions with the surrounding micro-environment
    • Caers J, Van Valckenborgh E, Menu E, Van Camp B, Vanderkerken K, (2008) Unraveling the biology of multiple myeloma disease: cancer stem cells, acquired intracellular changes and interactions with the surrounding micro-environment. Bull Cancer 95: 301-313.
    • (2008) Bull Cancer , vol.95 , pp. 301-313
    • Caers, J.1    Van Valckenborgh, E.2    Menu, E.3    Van Camp, B.4    Vanderkerken, K.5
  • 13
    • 0027133422 scopus 로고
    • Adhesion of human myeloma-derived cell lines to bone marrow stromal cells stimulates interleukin-6 secretion
    • Uchiyama H, Barut BA, Mohrbacher AF, Chauhan D, Anderson KC, (1993) Adhesion of human myeloma-derived cell lines to bone marrow stromal cells stimulates interleukin-6 secretion. Blood 82: 3712-3720.
    • (1993) Blood , vol.82 , pp. 3712-3720
    • Uchiyama, H.1    Barut, B.A.2    Mohrbacher, A.F.3    Chauhan, D.4    Anderson, K.C.5
  • 14
    • 0035195019 scopus 로고    scopus 로고
    • Adherence of multiple myeloma cells to bone marrow stromal cells upregulates vascular endothelial growth factor secretion: therapeutic applications
    • Gupta D, Treon SP, Shima Y, Hideshima T, Podar K, Tai YT, et al. (2001) Adherence of multiple myeloma cells to bone marrow stromal cells upregulates vascular endothelial growth factor secretion: therapeutic applications. Leukemia 15: 1950-1961.
    • (2001) Leukemia , vol.15 , pp. 1950-1961
    • Gupta, D.1    Treon, S.P.2    Shima, Y.3    Hideshima, T.4    Podar, K.5    Tai, Y.T.6
  • 15
    • 0036181668 scopus 로고    scopus 로고
    • Myeloma interacts with the bone marrow microenvironment to induce osteoclastogenesis and is dependent on osteoclast activity
    • Yaccoby S, Pearse RN, Johnson CL, Barlogie B, Choi Y, Epstein J, (2002) Myeloma interacts with the bone marrow microenvironment to induce osteoclastogenesis and is dependent on osteoclast activity. Br J Haematol 116: 278-290.
    • (2002) Br J Haematol , vol.116 , pp. 278-290
    • Yaccoby, S.1    Pearse, R.N.2    Johnson, C.L.3    Barlogie, B.4    Choi, Y.5    Epstein, J.6
  • 16
    • 34247556034 scopus 로고    scopus 로고
    • Bone marrow mesenchymal stem cells are abnormal in multiple myeloma
    • Corre J, Mahtouk K, Attal M, Gadelorge M, Huynh A, et al. (2007) Bone marrow mesenchymal stem cells are abnormal in multiple myeloma. Leukemia 21: 1079-1088.
    • (2007) Leukemia , vol.21 , pp. 1079-1088
    • Corre, J.1    Mahtouk, K.2    Attal, M.3    Gadelorge, M.4    Huynh, A.5
  • 18
    • 35148897797 scopus 로고    scopus 로고
    • Mesenchymal stem cell abnormalities in patients with multiple myeloma
    • Garderet L, Mazurier C, Chapel A, Ernou I, Boutin L, (2007) Mesenchymal stem cell abnormalities in patients with multiple myeloma. Leuk Lymphoma 48: 2032-2041.
    • (2007) Leuk Lymphoma , vol.48 , pp. 2032-2041
    • Garderet, L.1    Mazurier, C.2    Chapel, A.3    Ernou, I.4    Boutin, L.5
  • 20
    • 33750566914 scopus 로고    scopus 로고
    • Bortezomib reduces serum dickkopf-1 and receptor activator of nuclear factor-kappaB ligand concentrations and normalises indices of bone remodelling in patients with relapsed multiple myeloma
    • Terpos E, Heath DJ, Rahemtulla A, Zervas K, Chantry A, Anagnostopoulos A, et al. (2006) Bortezomib reduces serum dickkopf-1 and receptor activator of nuclear factor-kappaB ligand concentrations and normalises indices of bone remodelling in patients with relapsed multiple myeloma. Br J Haematol 135: 688-692.
    • (2006) Br J Haematol , vol.135 , pp. 688-692
    • Terpos, E.1    Heath, D.J.2    Rahemtulla, A.3    Zervas, K.4    Chantry, A.5    Anagnostopoulos, A.6
  • 21
    • 70849116391 scopus 로고    scopus 로고
    • Mesenchymal stromal cells promote or suppress the proliferation of T lymphocytes from cord blood and peripheral blood: the importance of low cell ratio and role of interleukin-6
    • Najar M, Rouas R, Raicevic G, Boufker HI, Lewalle P, Meuleman N, Bron D, (2009) Mesenchymal stromal cells promote or suppress the proliferation of T lymphocytes from cord blood and peripheral blood: the importance of low cell ratio and role of interleukin-6. Cytotherapy 11: 570-583.
    • (2009) Cytotherapy , vol.11 , pp. 570-583
    • Najar, M.1    Rouas, R.2    Raicevic, G.3    Boufker, H.I.4    Lewalle, P.5    Meuleman, N.6    Bron, D.7
  • 22
    • 4544245138 scopus 로고    scopus 로고
    • Isolation of BM mesenchymal stem cells by plastic adhesion or negative selection: phenotype, proliferation kinetics and differentiation potential
    • Tondreau T, Lagneaux L, Dejeneffe M, Delforge A, Massy M, (2004) Isolation of BM mesenchymal stem cells by plastic adhesion or negative selection: phenotype, proliferation kinetics and differentiation potential. Cytotherapy 6: 372-379.
    • (2004) Cytotherapy , vol.6 , pp. 372-379
    • Tondreau, T.1    Lagneaux, L.2    Dejeneffe, M.3    Delforge, A.4    Massy, M.5
  • 23
    • 79952133607 scopus 로고    scopus 로고
    • A rapid, simple, and reproducible method for the isolation of mesenchymal stromal cells from Wharton's jelly without enzymatic treatment
    • De Bruyn C, Najar M, Raicevic G, Meuleman N, Pieters K, Stamatopoulos B, (2011) A rapid, simple, and reproducible method for the isolation of mesenchymal stromal cells from Wharton's jelly without enzymatic treatment. Stem Cells Dev 20: 547-557.
    • (2011) Stem Cells Dev , vol.20 , pp. 547-557
    • De Bruyn, C.1    Najar, M.2    Raicevic, G.3    Meuleman, N.4    Pieters, K.5    Stamatopoulos, B.6
  • 24
    • 0017694555 scopus 로고
    • Conditions controlling the proliferation of haemopoietic stem cells in vitro
    • Dexter TM, Allen TD, Lajtha LG, (1977) Conditions controlling the proliferation of haemopoietic stem cells in vitro. J Cell Physiol 91: 335-344.
    • (1977) J Cell Physiol , vol.91 , pp. 335-344
    • Dexter, T.M.1    Allen, T.D.2    Lajtha, L.G.3
  • 25
    • 61449172037 scopus 로고    scopus 로고
    • Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources
    • Huang DW, Sherman BT, Lempicki RA, (2009) Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources. Nat Protoc 4: 44-57.
    • (2009) Nat Protoc , vol.4 , pp. 44-57
    • Huang, D.W.1    Sherman, B.T.2    Lempicki, R.A.3
  • 26
    • 58549112996 scopus 로고    scopus 로고
    • Bioinformatics enrichment tools: paths toward the comprehensive functional analysis of large gene lists
    • Huang DW, Sherman BT, Lempicki RA, (2009) Bioinformatics enrichment tools: paths toward the comprehensive functional analysis of large gene lists. Nucleic Acids Res 37: 1-13.
    • (2009) Nucleic Acids Res , vol.37 , pp. 1-13
    • Huang, D.W.1    Sherman, B.T.2    Lempicki, R.A.3
  • 27
    • 47249166372 scopus 로고    scopus 로고
    • Replicative senescence of mesenchymal stem cells: a continuous and organized process
    • Wagner W, Horn P, Castoldi M, Diehlmann A, Bork S, Saffrich R, et al. (2008) Replicative senescence of mesenchymal stem cells: a continuous and organized process. PLoS One 3: e2213.
    • (2008) PLoS One , vol.3
    • Wagner, W.1    Horn, P.2    Castoldi, M.3    Diehlmann, A.4    Bork, S.5    Saffrich, R.6
  • 28
    • 79952650332 scopus 로고    scopus 로고
    • Knockdown of p21(Cip1/Waf1) enhances proliferation, the expression of stemness markers, and osteogenic potential in human mesenchymal stem cells
    • Yew TL, Chiu FY, Tsai CC, Chen HL, Lee WP, Chen YJ, Chang MC, Hung SC, (2011) Knockdown of p21(Cip1/Waf1) enhances proliferation, the expression of stemness markers, and osteogenic potential in human mesenchymal stem cells. Aging Cell 10: 349-361.
    • (2011) Aging Cell , vol.10 , pp. 349-361
    • Yew, T.L.1    Chiu, F.Y.2    Tsai, C.C.3    Chen, H.L.4    Lee, W.P.5    Chen, Y.J.6    Chang, M.C.7    Hung, S.C.8
  • 30
    • 33845513318 scopus 로고    scopus 로고
    • Phenotypic and functional characterization of bone marrow mesenchymal stem cells derived from patients with multiple myeloma
    • Arnulf B, Lecourt S, Soulier J, Ternaux B, Lacassagne MN, Crinquette A, et al. (2007) Phenotypic and functional characterization of bone marrow mesenchymal stem cells derived from patients with multiple myeloma. Leukemia 21: 158-163.
    • (2007) Leukemia , vol.21 , pp. 158-163
    • Arnulf, B.1    Lecourt, S.2    Soulier, J.3    Ternaux, B.4    Lacassagne, M.N.5    Crinquette, A.6
  • 31
    • 74249093697 scopus 로고    scopus 로고
    • Distinct transcriptional profiles characterize bone microenvironment mesenchymal cells rather than osteoblasts in relationship with multiple myeloma bone disease
    • Todoerti K, Lisignoli G, Storti P, Agnelli L, Novara F, et al. (2010) Distinct transcriptional profiles characterize bone microenvironment mesenchymal cells rather than osteoblasts in relationship with multiple myeloma bone disease. Exp Hematol 38: 141-153.
    • (2010) Exp Hematol , vol.38 , pp. 141-153
    • Todoerti, K.1    Lisignoli, G.2    Storti, P.3    Agnelli, L.4    Novara, F.5
  • 32
    • 78751705462 scopus 로고    scopus 로고
    • In vitro growth of hematopoietic progenitors and stromal bone marrow cells from patients with multiple myeloma
    • Martinez-Jaramillo G, Vela-Ojeda J, Flores-Guzman P, Mayani H, (2011) In vitro growth of hematopoietic progenitors and stromal bone marrow cells from patients with multiple myeloma. Leuk Res 35: 250-255.
    • (2011) Leuk Res , vol.35 , pp. 250-255
    • Martinez-Jaramillo, G.1    Vela-Ojeda, J.2    Flores-Guzman, P.3    Mayani, H.4
  • 33
    • 79954429504 scopus 로고    scopus 로고
    • Isolation and comparison of mesenchymal stem-like cells from human gastric cancer and adjacent non-cancerous tissues
    • Xu X, Zhang X, Wang S, Qian H, Zhu W, Cao H, Wang M, Chen Y, Xu W, (2011) Isolation and comparison of mesenchymal stem-like cells from human gastric cancer and adjacent non-cancerous tissues. J Cancer Res Clin Oncol 137: 495-504.
    • (2011) J Cancer Res Clin Oncol , vol.137 , pp. 495-504
    • Xu, X.1    Zhang, X.2    Wang, S.3    Qian, H.4    Zhu, W.5    Cao, H.6    Wang, M.7    Chen, Y.8    Xu, W.9
  • 34
    • 13944270339 scopus 로고    scopus 로고
    • Senescent cells, tumor suppression, and organismal aging: good citizens, bad neighbors
    • Campisi J, (2005) Senescent cells, tumor suppression, and organismal aging: good citizens, bad neighbors. Cell 120: 513-522.
    • (2005) Cell , vol.120 , pp. 513-522
    • Campisi, J.1
  • 36
    • 77954659535 scopus 로고    scopus 로고
    • Bone osteoblastic and mesenchymal stromal cells lack primarily tumoral features in multiple myeloma patients
    • Giuliani N, Lisignoli G, Novara F, Storti P, Zaffaroni N, Villa R, et al. (2010) Bone osteoblastic and mesenchymal stromal cells lack primarily tumoral features in multiple myeloma patients. Leukemia 24: 1368-1370.
    • (2010) Leukemia , vol.24 , pp. 1368-1370
    • Giuliani, N.1    Lisignoli, G.2    Novara, F.3    Storti, P.4    Zaffaroni, N.5    Villa, R.6
  • 37
    • 77949881221 scopus 로고    scopus 로고
    • The senescence-associated secretory phenotype: the dark side of tumor suppression
    • Coppe JP, Desprez PY, Krtolica A, Campisi J, (2010) The senescence-associated secretory phenotype: the dark side of tumor suppression. Annu Rev Pathol 5: 99-118.
    • (2010) Annu Rev Pathol , vol.5 , pp. 99-118
    • Coppe, J.P.1    Desprez, P.Y.2    Krtolica, A.3    Campisi, J.4
  • 38
    • 84911808355 scopus 로고    scopus 로고
    • Inflammation and Toll-Like Receptor Ligation Differentially Affect the Osteogenic Potential of Human Mesenchymal Stromal Cells Depending on Their Tissue Origin
    • Raicevic G, Najar M, Pieters K, De Bruyn C, Meuleman N, Bron D, Toungouz M, Lagneaux L, (2012) Inflammation and Toll-Like Receptor Ligation Differentially Affect the Osteogenic Potential of Human Mesenchymal Stromal Cells Depending on Their Tissue Origin. Tissue Eng Part A 18(13-14): 1410-8.
    • (2012) Tissue Eng Part A , vol.18 , Issue.13-14 , pp. 1410-1418
    • Raicevic, G.1    Najar, M.2    Pieters, K.3    De Bruyn, C.4    Meuleman, N.5    Bron, D.6    Toungouz, M.7    Lagneaux, L.8
  • 39
    • 80855163623 scopus 로고    scopus 로고
    • Replicative senescence of mesenchymal stem cells causes DNA-methylation changes which correlate with repressive histone marks
    • Schellenberg A, Lin Q, Schuler H, Koch CM, Joussen S, (2011) Replicative senescence of mesenchymal stem cells causes DNA-methylation changes which correlate with repressive histone marks. Aging (Albany NY) 3: 873-888.
    • (2011) Aging (Albany NY) , vol.3 , pp. 873-888
    • Schellenberg, A.1    Lin, Q.2    Schuler, H.3    Koch, C.M.4    Joussen, S.5
  • 40
    • 36249023410 scopus 로고    scopus 로고
    • Elevated tumor necrosis factor-alpha suppresses TAZ expression and impairs osteogenic potential of Flk-1+ mesenchymal stem cells in patients with multiple myeloma
    • Li B, Shi M, Li J, Zhang H, Chen B, Chen L, Gao W, Giuliani N, Zhao RC, (2007) Elevated tumor necrosis factor-alpha suppresses TAZ expression and impairs osteogenic potential of Flk-1+ mesenchymal stem cells in patients with multiple myeloma. Stem Cells Dev 16: 921-930.
    • (2007) Stem Cells Dev , vol.16 , pp. 921-930
    • Li, B.1    Shi, M.2    Li, J.3    Zhang, H.4    Chen, B.5    Chen, L.6    Gao, W.7    Giuliani, N.8    Zhao, R.C.9
  • 41
    • 69549103081 scopus 로고    scopus 로고
    • Fenretinide inhibits myeloma cell growth, osteoclastogenesis and osteoclast viability
    • Li X, Ling W, Pennisi A, Khan S, Yaccoby S, (2009) Fenretinide inhibits myeloma cell growth, osteoclastogenesis and osteoclast viability. Cancer Lett 284: 175-181.
    • (2009) Cancer Lett , vol.284 , pp. 175-181
    • Li, X.1    Ling, W.2    Pennisi, A.3    Khan, S.4    Yaccoby, S.5
  • 42
    • 0346363760 scopus 로고    scopus 로고
    • The role of the Wnt-signaling antagonist DKK1 in the development of osteolytic lesions in multiple myeloma
    • Tian E, Zhan F, Walker R, Rasmussen E, Ma Y, Barlogie B, Shaughnessy JDJ, (2003) The role of the Wnt-signaling antagonist DKK1 in the development of osteolytic lesions in multiple myeloma. N Engl J Med 349: 2483-2494.
    • (2003) N Engl J Med , vol.349 , pp. 2483-2494
    • Tian, E.1    Zhan, F.2    Walker, R.3    Rasmussen, E.4    Ma, Y.5    Barlogie, B.6    Shaughnessy, J.D.J.7
  • 43
    • 33745494534 scopus 로고    scopus 로고
    • A crosstalk between myeloma cells and marrow stromal cells stimulates production of DKK1 and interleukin-6: a potential role in the development of lytic bone disease and tumor progression in multiple myeloma
    • Gunn WG, Conley A, Deininger L, Olson SD, Prockop DJ, Gregory CA, (2006) A crosstalk between myeloma cells and marrow stromal cells stimulates production of DKK1 and interleukin-6: a potential role in the development of lytic bone disease and tumor progression in multiple myeloma. Stem Cells 24: 986-991.
    • (2006) Stem Cells , vol.24 , pp. 986-991
    • Gunn, W.G.1    Conley, A.2    Deininger, L.3    Olson, S.D.4    Prockop, D.J.5    Gregory, C.A.6
  • 44
    • 47149088471 scopus 로고    scopus 로고
    • Cytokines regulating hematopoietic stem cell function
    • Zhang CC, Lodish HF, (2008) Cytokines regulating hematopoietic stem cell function. Curr Opin Hematol 15: 307-311.
    • (2008) Curr Opin Hematol , vol.15 , pp. 307-311
    • Zhang, C.C.1    Lodish, H.F.2
  • 45
    • 0030048429 scopus 로고    scopus 로고
    • Stem cell factor as a survival and growth factor in human normal and malignant hematopoiesis
    • Hassan HT, Zander A, (1996) Stem cell factor as a survival and growth factor in human normal and malignant hematopoiesis. Acta Haematol 95: 257-262.
    • (1996) Acta Haematol , vol.95 , pp. 257-262
    • Hassan, H.T.1    Zander, A.2
  • 46
    • 0026080735 scopus 로고
    • Administration of interleukin-6 stimulates multilineage hematopoiesis and accelerates recovery from radiation-induced hematopoietic depression
    • Patchen ML, MacVittie TJ, Williams JL, Schwartz GN, Souza LM, (1991) Administration of interleukin-6 stimulates multilineage hematopoiesis and accelerates recovery from radiation-induced hematopoietic depression. Blood 77: 472-480.
    • (1991) Blood , vol.77 , pp. 472-480
    • Patchen, M.L.1    MacVittie, T.J.2    Williams, J.L.3    Schwartz, G.N.4    Souza, L.M.5
  • 47
    • 1642371165 scopus 로고    scopus 로고
    • Insulin-like growth factor 2 expressed in a novel fetal liver cell population is a growth factor for hematopoietic stem cells
    • Zhang CC, Lodish HF, (2004) Insulin-like growth factor 2 expressed in a novel fetal liver cell population is a growth factor for hematopoietic stem cells. Blood 103: 2513-2521.
    • (2004) Blood , vol.103 , pp. 2513-2521
    • Zhang, C.C.1    Lodish, H.F.2
  • 48
    • 84862907620 scopus 로고    scopus 로고
    • Human umbilical cord Wharton's jelly stem cells and its conditioned medium support hematopoietic stem cell expansion ex vivo
    • Fong CY, Gauthaman K, Cheyyatraivendran S, Lin HD, Biswas A, Bongso A, (2012) Human umbilical cord Wharton's jelly stem cells and its conditioned medium support hematopoietic stem cell expansion ex vivo. J Cell Biochem 113: 658-668.
    • (2012) J Cell Biochem , vol.113 , pp. 658-668
    • Fong, C.Y.1    Gauthaman, K.2    Cheyyatraivendran, S.3    Lin, H.D.4    Biswas, A.5    Bongso, A.6
  • 49
    • 0032213273 scopus 로고    scopus 로고
    • Stat3 activation is responsible for IL-6-dependent T cell proliferation through preventing apoptosis: generation and characterization of T cell-specific Stat3-deficient mice
    • Takeda K, Kaisho T, Yoshida N, Takeda J, Kishimoto T, Akira S, (1998) Stat3 activation is responsible for IL-6-dependent T cell proliferation through preventing apoptosis: generation and characterization of T cell-specific Stat3-deficient mice. J Immunol 161: 4652-4660.
    • (1998) J Immunol , vol.161 , pp. 4652-4660
    • Takeda, K.1    Kaisho, T.2    Yoshida, N.3    Takeda, J.4    Kishimoto, T.5    Akira, S.6
  • 51
    • 77956431440 scopus 로고    scopus 로고
    • Bone marrow stromal cells from myeloma patients support the growth of myeloma stem cells
    • Feng Y, Wen J, Mike P, Choi DS, Eshoa C, Shi ZZ, Zu Y, Chang CC, (2010) Bone marrow stromal cells from myeloma patients support the growth of myeloma stem cells. Stem Cells Dev 19: 1289-1296.
    • (2010) Stem Cells Dev , vol.19 , pp. 1289-1296
    • Feng, Y.1    Wen, J.2    Mike, P.3    Choi, D.S.4    Eshoa, C.5    Shi, Z.Z.6    Zu, Y.7    Chang, C.C.8
  • 53
    • 45849119799 scopus 로고    scopus 로고
    • Abnormal cytokine production by bone marrow stromal cells of multiple myeloma patients in response to RPMI8226 myeloma cells
    • Zdzisinska B, Bojarska-Junak A, Dmoszynska A, Kandefer-Szerszen M, (2008) Abnormal cytokine production by bone marrow stromal cells of multiple myeloma patients in response to RPMI8226 myeloma cells. Arch Immunol Ther Exp (Warsz) 56: 207-221.
    • (2008) Arch Immunol Ther Exp (Warsz) , vol.56 , pp. 207-221
    • Zdzisinska, B.1    Bojarska-Junak, A.2    Dmoszynska, A.3    Kandefer-Szerszen, M.4
  • 54
    • 77950862042 scopus 로고    scopus 로고
    • Bone progenitor dysfunction induces myelodysplasia and secondary leukaemia
    • Raaijmakers MHGP, Mukherjee S, Guo S, Zhang S, Kobayashi T, et al. (2010) Bone progenitor dysfunction induces myelodysplasia and secondary leukaemia. Nature 464: 852-857.
    • (2010) Nature , vol.464 , pp. 852-857
    • Raaijmakers, M.H.G.P.1    Mukherjee, S.2    Guo, S.3    Zhang, S.4    Kobayashi, T.5
  • 55
    • 79551627594 scopus 로고    scopus 로고
    • Association of multiple myeloma with different neoplasms: systematic analysis in consecutive patients with myeloma
    • Hasskarl J, Ihorst G, De Pasquale D, Schrottner P, Zerweck A, Wasch R, Engelhardt M, (2011) Association of multiple myeloma with different neoplasms: systematic analysis in consecutive patients with myeloma. Leuk Lymphoma 52: 247-259.
    • (2011) Leuk Lymphoma , vol.52 , pp. 247-259
    • Hasskarl, J.1    Ihorst, G.2    De Pasquale, D.3    Schrottner, P.4    Zerweck, A.5    Wasch, R.6    Engelhardt, M.7
  • 57
    • 79961006281 scopus 로고    scopus 로고
    • Human ovarian carcinoma-associated mesenchymal stem cells regulate cancer stem cells and tumorigenesis via altered BMP production
    • McLean K, Gong Y, Choi Y, Deng N, Yang K, Bai S, Cabrera L, Keller E, et al. (2011) Human ovarian carcinoma-associated mesenchymal stem cells regulate cancer stem cells and tumorigenesis via altered BMP production. J Clin Invest 121: 3206-3219.
    • (2011) J Clin Invest , vol.121 , pp. 3206-3219
    • McLean, K.1    Gong, Y.2    Choi, Y.3    Deng, N.4    Yang, K.5    Bai, S.6    Cabrera, L.7    Keller, E.8
  • 58
    • 2342640981 scopus 로고    scopus 로고
    • Radiation to stromal fibroblasts increases invasiveness of pancreatic cancer cells through tumor-stromal interactions
    • Ohuchida K, Mizumoto K, Murakami M, Qian LW, Sato N, Nagai E, et al. (2004) Radiation to stromal fibroblasts increases invasiveness of pancreatic cancer cells through tumor-stromal interactions. Cancer Res 64: 3215-3222.
    • (2004) Cancer Res , vol.64 , pp. 3215-3222
    • Ohuchida, K.1    Mizumoto, K.2    Murakami, M.3    Qian, L.W.4    Sato, N.5    Nagai, E.6
  • 59
    • 34948896045 scopus 로고    scopus 로고
    • Mesenchymal stem cells within tumour stroma promote breast cancer metastasis
    • Karnoub AE, Dash AB, Vo AP, Sullivan A, Brooks MW, Bell GW, et al. (2007) Mesenchymal stem cells within tumour stroma promote breast cancer metastasis. Nature 449: 557-563.
    • (2007) Nature , vol.449 , pp. 557-563
    • Karnoub, A.E.1    Dash, A.B.2    Vo, A.P.3    Sullivan, A.4    Brooks, M.W.5    Bell, G.W.6
  • 60
    • 0242410394 scopus 로고    scopus 로고
    • Immunosuppressive effect of mesenchymal stem cells favors tumor growth in allogeneic animals
    • Djouad F, Plence P, Bony C, Tropel P, Apparailly F, (2003) Immunosuppressive effect of mesenchymal stem cells favors tumor growth in allogeneic animals. Blood 102: 3837-3844.
    • (2003) Blood , vol.102 , pp. 3837-3844
    • Djouad, F.1    Plence, P.2    Bony, C.3    Tropel, P.4    Apparailly, F.5
  • 61
    • 77949458344 scopus 로고    scopus 로고
    • A human-like senescence-associated secretory phenotype is conserved in mouse cells dependent on physiological oxygen
    • Coppe JP, Patil CK, Rodier F, Krtolica A, Beausejour CM, Parrinello S,et al. 2010) A human-like senescence-associated secretory phenotype is conserved in mouse cells dependent on physiological oxygen. PLoS One 5: e9188.
    • (2010) PLoS One , vol.5
    • Coppe, J.P.1    Patil, C.K.2    Rodier, F.3    Krtolica, A.4    Beausejour, C.M.5    Parrinello, S.6
  • 62
    • 84891713034 scopus 로고    scopus 로고
    • Senescence-associated secretory phenotypes reveal cell-nonautonomous functions of oncogenic RAS and the p53 tumor suppressor
    • Coppe JP, Patil CK, Rodier F, Sun Y, Munoz DP, et al. (2008) Senescence-associated secretory phenotypes reveal cell-nonautonomous functions of oncogenic RAS and the p53 tumor suppressor. PLoS Biol 6: 2853-2868.
    • (2008) PLoS Biol , vol.6 , pp. 2853-2868
    • Coppe, J.P.1    Patil, C.K.2    Rodier, F.3    Sun, Y.4    Munoz, D.P.5
  • 63
    • 79959996812 scopus 로고    scopus 로고
    • Accelerated aging in the tumor microenvironment: connecting aging, inflammation and cancer metabolism with personalized medicine
    • Lisanti MP, Martinez-Outschoorn UE, Pavlides S, Whitaker-Menezes D, Pestell RG, (2011) Accelerated aging in the tumor microenvironment: connecting aging, inflammation and cancer metabolism with personalized medicine. Cell Cycle 10: 2059-2063.
    • (2011) Cell Cycle , vol.10 , pp. 2059-2063
    • Lisanti, M.P.1    Martinez-Outschoorn, U.E.2    Pavlides, S.3    Whitaker-Menezes, D.4    Pestell, R.G.5
  • 64
    • 34447639255 scopus 로고    scopus 로고
    • Transplantation of mesenchymal stem cells to enhance engraftment of hematopoietic stem cells
    • Le Blanc K, Samuelsson H, Gustafsson B, Remberger M, Sundberg B, (2007) Transplantation of mesenchymal stem cells to enhance engraftment of hematopoietic stem cells. Leukemia 21: 1733-1738.
    • (2007) Leukemia , vol.21 , pp. 1733-1738
    • Le Blanc, K.1    Samuelsson, H.2    Gustafsson, B.3    Remberger, M.4    Sundberg, B.5
  • 65
    • 84860841648 scopus 로고    scopus 로고
    • In vitro anti-myeloma activity of TRAIL-expressing adipose-derived mesenchymal stem cells
    • Ciavarella S, Grisendi G, Dominici M, Tucci M, Brunetti O, (2012) Dammacco (2012) In vitro anti-myeloma activity of TRAIL-expressing adipose-derived mesenchymal stem cells. Br J Haematol 157: 586-598.
    • (2012) Br J Haematol , vol.157 , pp. 586-598
    • Ciavarella, S.1    Grisendi, G.2    Dominici, M.3    Tucci, M.4    Brunetti, O.5    Dammacco6
  • 66
    • 10744226505 scopus 로고    scopus 로고
    • Insights into the multistep transformation of MGUS to myeloma using microarray expression analysis
    • Davies FE, Dring AM, Li C, Rawstron AC, Shammas MA, et al. (2003) Insights into the multistep transformation of MGUS to myeloma using microarray expression analysis. Blood 102: 4504-4511.
    • (2003) Blood , vol.102 , pp. 4504-4511
    • Davies, F.E.1    Dring, A.M.2    Li, C.3    Rawstron, A.C.4    Shammas, M.A.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.