Experimental evaluation and computational modeling of the effects of encapsulation on the time-profile of glucose-stimulated insulin release of pancreatic islets

BioMedical Engineering Online

Volumn 14, Issue 1, 2015, Pages

  Buchwald, Peter ^a,b   Cechin, Sirlene R ^a   Weaver, Jessica D ^a,b   Stabler, Cherie L ^a,b  

^a UNIVERSITY OF MIAMI   (United States)

^b UNIVERSITY OF MIAMI MILLER SCHOOL OF MEDICINE   (United States)

Author keywords

Alginate; Diabetes mellitus; FEM model; Glucose stimulated insulin release; Hill equation; Islet encapsulation; Islet perifusion

Indexed keywords

ALGINATE; CHARACTERIZATION; COMPUTATION THEORY; FINITE ELEMENT METHOD; GLUCOSE; MICROENCAPSULATION; PHYSIOLOGY; WELL STIMULATION;

DIABETES MELLITUS; FEM MODELING; HILL EQUATION; INSULIN RELEASE; ISLET ENCAPSULATIONS; ISLET PERIFUSION;

INSULIN;

GLUCOSE; INSULIN; MICROCAPSULE;

ANIMAL CELL; ARTICLE; CELL ENCAPSULATION; CONTROLLED STUDY; EXPERIMENTAL STUDY; FINITE ELEMENT ANALYSIS; INSULIN RELEASE; INSULIN RESPONSE; MATHEMATICAL MODEL; MICROENCAPSULATION; MOUSE; NONHUMAN; PANCREAS ISLET; PANCREAS ISLET CELL; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; ANIMAL; BIOLOGICAL MODEL; COMPUTER SIMULATION; DRUG EFFECTS; KINETICS; MICROCAPSULE; PERFUSION; SECRETION (PROCESS);

MURINAE;

ANIMALS; CAPSULES; COMPUTER SIMULATION; FINITE ELEMENT ANALYSIS; GLUCOSE; INSULIN; ISLETS OF LANGERHANS; KINETICS; MICE; MODELS, BIOLOGICAL; PERFUSION;

EID: 84928046077     PISSN: None     EISSN: 1475925X     Source Type: Journal    
DOI: 10.1186/s12938-015-0021-9     Document Type: Article

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