Insights into interstitial flow, shear stress, and mass transport effects on ECM heterogeneity in bioreactor-cultivated engineered cartilage hydrogels

Biomechanics and Modeling in Mechanobiology

Volumn 11, Issue 5, 2012, Pages 689-702

  Chen, Tony ^a,b   Buckley, Mark ^c   Cohen, Itai ^c   Bonassar, Lawrence ^c   Awad, Hani A ^a,b  

^a University of Rochester   (United States)

^b UNIVERSITY OF ROCHESTER MEDICAL CENTER   (United States)

^c School of Operations Research and Industrial Engineering   (United States)

Author keywords

Bioreactors; Cartilage; Computational fluid dynamics (CFD); Fluorescence recovery after photobleaching (FRAP); Interstitial flow; Permeability; Shear Stress; Tissue engineering

Indexed keywords

BIOCONVERSION; BOUNDARY LAYERS; CARTILAGE; COMPUTATIONAL FLUID DYNAMICS; FLOW VELOCITY; FLUORESCENCE; HYDROGELS; MECHANICAL PERMEABILITY; PHOTOBLEACHING; SCAFFOLDS (BIOLOGY); SHEAR FLOW; SHEAR STRESS;

COMPUTATIONAL FLUID DYNAMIC; ENGINEERED CARTILAGE; FLUORESCENCE RECOVERY AFTER PHOTOBLEACHING; HYDROGEL SURFACES; INTERFACIAL SHEAR STRESS; INTERSTITIAL FLOW; INTERSTITIALS; PERMEABILITY; TISSUES ENGINEERINGS;

BIOREACTORS;

COLLAGEN; GLYCOSAMINOGLYCAN;

ANIMAL; ARTICLE; BIOREACTOR; CARTILAGE; EXTRACELLULAR MATRIX; FLUORESCENCE; HUMAN; HYDROGEL; METABOLISM; PERMEABILITY; PHYSIOLOGICAL STRESS; PHYSIOLOGY; TISSUE ENGINEERING;

ANIMALS; BIOREACTORS; CARTILAGE; COLLAGEN; EXTRACELLULAR MATRIX; FLUORESCENCE; GLYCOSAMINOGLYCANS; HUMANS; HYDROGELS; PERMEABILITY; STRESS, PHYSIOLOGICAL; TISSUE ENGINEERING;

EID: 84861097493     PISSN: 16177959     EISSN: 16177940     Source Type: Journal    
DOI: 10.1007/s10237-011-0343-x     Document Type: Article

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