MiR-10b-5p expression in Huntington's disease brain relates to age of onset and the extent of striatal involvement

BMC Medical Genomics

Volumn 8, Issue 1, 2015, Pages

  Hoss, Andrew G ^a   Labadorf, Adam ^a,b   Latourelle, Jeanne C ^a   Kartha, Vinay K ^b   Hadzi, Tiffany C ^a   Gusella, James F ^c   MacDonald, Marcy E ^c   Chen, Jiang Fan ^a   Akbarian, Schahram ^d   Weng, Zhiping ^e   Vonsattel, Jean Paul ^f   Myers, Richard H ^a  

^a BOSTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b BOSTON UNIVERSITY   (United States)

^c MASSACHUSETTS GENERAL HOSPITAL   (United States)

^d MOUNT SINAI SCHOOL OF MEDICINE   (United States)

^e UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL   (United States)

^f NewYork Presbyterian Hospital   (United States)

Author keywords

Age at onset; Human; Huntington's disease; microRNA; miRNA; miRNA sequencing; Neuropathological involvement; Prefrontal cortex; RNA biology; Striatum

Indexed keywords

MICRORNA; MICRORNA 106A 5P; MICRORNA 10B; MICRORNA 10B 3P; MICRORNA 10B 5P; MICRORNA 129; MICRORNA 129 3P; MICRORNA 129 5P; MICRORNA 1298; MICRORNA 1298 5P; MICRORNA 132 3P; MICRORNA 142; MICRORNA 144; MICRORNA 144 5P; MICRORNA 148A; MICRORNA 148A 3P; MICRORNA 194 5P; MICRORNA 196A 5P; MICRORNA 196B 5P; MICRORNA 200C 3P; MICRORNA 223 3P; MICRORNA 302A; MICRORNA 302A 3P; MICRORNA 4448; MICRORNA 4449; MICRORNA 486; MICRORNA 486 5P; MICRORNA 490 5P; MICRORNA 615 3P; UNCLASSIFIED DRUG; MIRN10 MICRORNA, HUMAN;

3' UNTRANSLATED REGION; 5' UNTRANSLATED REGION; ARTICLE; ASSESSMENT OF HUMANS; CAG REPEAT; CLINICAL FEATURE; CONTROLLED STUDY; CORPUS STRIATUM; DOWN REGULATION; GENE EXPRESSION; GENE EXPRESSION REGULATION; GENE FUNCTION; GENE IDENTIFICATION; GENETIC ASSOCIATION; HADZI VONSATTEL STRIATAL AND CORTICAL SCORE; HUMAN; HUMAN TISSUE; HUNTINGTON CHOREA; NERVE DEGENERATION; NEUROPATHOLOGY; NEXT GENERATION SEQUENCING; ONSET AGE; PREDICTIVE VALUE; PREFRONTAL CORTEX; PRIORITY JOURNAL; RECEIVER OPERATING CHARACTERISTIC; RNA ANALYSIS; RNA SEQUENCE; SENSITIVITY AND SPECIFICITY; TRANSCRIPTION REGULATION; UPREGULATION; VONSATTEL GRADE; ADULT; AGED; BRAIN; BRAIN CORTEX; DISEASE COURSE; FEMALE; GENE EXPRESSION PROFILING; GENETICS; HIGH THROUGHPUT SEQUENCING; MALE; METABOLISM; MIDDLE AGED; PATHOLOGY; STATISTICAL MODEL;

ADULT; AGE OF ONSET; AGED; BRAIN; CEREBRAL CORTEX; CORPUS STRIATUM; DISEASE PROGRESSION; FEMALE; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; HIGH-THROUGHPUT NUCLEOTIDE SEQUENCING; HUMANS; HUNTINGTON DISEASE; LINEAR MODELS; MALE; MICRORNAS; MIDDLE AGED;

EID: 84928042935     PISSN: None     EISSN: 17558794     Source Type: Journal    
DOI: 10.1186/s12920-015-0083-3     Document Type: Article

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