Alcohol inhibits osteopontin-dependent transforming growth factor-β1 expression in human mesenchymal stem cells

Journal of Biological Chemistry

Volumn 290, Issue 16, 2015, Pages 9959-9973

  Driver, Joseph ^a   Weber, Cynthia E ^a   Callaci, John J ^a   Kothari, Anai N ^a   Zapf, Matthew A ^a   Roper, Philip M ^a   Borys, Dariusz ^a   Franzen, Carrie A ^a   Gupta, Gopal N ^a   Wai, Philip Y ^a   Zhang, Jiwang ^a   Denning, Mitchell F ^a   Kuo, Paul C ^a   Mi, Zhiyong ^a  

^a LOYOLA UNIVERSITY MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BIOMECHANICS; BONE; CELL CULTURE; FRACTURE; HEALTH RISKS; PROTEINS; TRANSCRIPTION;

FRACTURE HEALING; HUMAN MESENCHYMAL STEM CELLS; MESENCHYMAL STEM CELL; MOLECULAR MECHANISM; PROTEIN EXPRESSIONS; SIGNALING PATHWAYS; TRANSFORMING GROWTH FACTORS; TRAUMATIC INJURY;

STEM CELLS;

ALCOHOL; CELL SURFACE RECEPTOR; COLLAGEN TYPE 1; CYCLIC AMP DEPENDENT PROTEIN KINASE; MYELOID ZINC FINGER 1; OSTEOPONTIN; RNA POLYMERASE II; TRANSCRIPTION FACTOR GATA 4; TRANSCRIPTION FACTOR SOX9; TRANSFORMING GROWTH FACTOR BETA1; UNCLASSIFIED DRUG; ZINC FINGER PROTEIN; APTAMER; KRUPPEL LIKE FACTOR; LUCIFERASE; MZF1 PROTEIN, HUMAN; MZF1 PROTEIN, MOUSE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BINDING SITE; CARTILAGE CELL; CELL DIFFERENTIATION; COLLAGEN 1 GENE; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME BINDING; ENZYME PHOSPHORYLATION; FRACTURE HEALING; GATA4 GENE; GENE; GENE ACTIVATION; GENE EXPRESSION REGULATION; HUMAN; HUMAN CELL; MALE; MESENCHYMAL STEM CELL; MOUSE; MZF1 GENE; NONHUMAN; OSTEOBLAST; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN BINDING; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; PROTEIN PROTEIN INTERACTION; PROTEIN SYNTHESIS INHIBITION; SIGNAL TRANSDUCTION; SOX 9 GENE; TGF BETA1 GENE; TRANSCRIPTION INITIATION; ANIMAL; ANTAGONISTS AND INHIBITORS; C57BL MOUSE; DRUG EFFECTS; GENETICS; INJURIES; MESENCHYMAL STROMA CELL; METABOLISM; PATHOLOGY; PHOSPHORYLATION; TIBIA; TIBIA FRACTURE;

ANIMALIA;

ANIMALS; APTAMERS, NUCLEOTIDE; CELL DIFFERENTIATION; ETHANOL; FRACTURE HEALING; GENE EXPRESSION REGULATION; HUMANS; KRUPPEL-LIKE TRANSCRIPTION FACTORS; LUCIFERASES; MALE; MESENCHYMAL STROMAL CELLS; MICE; MICE, INBRED C57BL; OSTEOPONTIN; PHOSPHORYLATION; SIGNAL TRANSDUCTION; TIBIA; TIBIAL FRACTURES; TRANSFORMING GROWTH FACTOR BETA1;

EID: 84928036552     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M114.616888     Document Type: Article

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