메뉴 건너뛰기




Volumn 138, Issue 3, 2015, Pages 616-631

Differential DNA methylation profiles of coding and non-coding genes define hippocampal sclerosis in human temporal lobe epilepsy

Author keywords

DNA methylation; Epigenetics; Long non coding RNA; microRNA; Temporal lobe epilepsy

Indexed keywords

CARBAMAZEPINE; CLONAZEPAM; DIAZEPAM; ETIRACETAM; LONG UNTRANSLATED RNA; MICRORNA; NEUROTRANSMITTER; OXCARBAZEPINE; PHENYTOIN; UNTRANSLATED RNA; ZONISAMIDE;

EID: 84927976254     PISSN: 00068950     EISSN: 14602156     Source Type: Journal    
DOI: 10.1093/brain/awu373     Document Type: Article
Times cited : (138)

References (60)
  • 2
    • 84859412462 scopus 로고    scopus 로고
    • Genome-wide DNA methylation differences between late-onset Alzheimer's disease and cognitively normal controls in human frontal cortex
    • Bakulski KM, Dolinoy DC, Sartor MA, Paulson HL, Konen JR, Lieberman AP, et al. Genome-wide DNA methylation differences between late-onset Alzheimer's disease and cognitively normal controls in human frontal cortex. J Alzheimer Dis 2012; 29: 571-88.
    • (2012) J Alzheimer Dis , vol.29 , pp. 571-588
    • Bakulski, K.M.1    Dolinoy, D.C.2    Sartor, M.A.3    Paulson, H.L.4    Konen, J.R.5    Lieberman, A.P.6
  • 3
    • 84879793001 scopus 로고    scopus 로고
    • International consensus classification of hippocam-pal sclerosis in temporal lobe epilepsy: A task force report from the ILAE commission on diagnostic methods
    • Blumcke I, Thom M, Aronica E, Armstrong DD, Bartolomei F, Bernasconi A, et al. International consensus classification of hippocam-pal sclerosis in temporal lobe epilepsy: a task force report from the ILAE commission on diagnostic methods. Epilepsia 2013; 54: 1315-29.
    • (2013) Epilepsia , vol.54 , pp. 1315-1329
    • Blumcke, I.1    Thom, M.2    Aronica, E.3    Armstrong, D.D.4    Bartolomei, F.5    Bernasconi, A.6
  • 5
    • 79953172603 scopus 로고    scopus 로고
    • Genome-wide DNA methylation analysis of neuroblastic tumors reveals clinically relevant epigenetic events and large-scale epigenomic alterations localized to telomeric regions
    • Buckley PG, Das S, Bryan K, Watters KM, Alcock L, Koster J, et al. Genome-wide DNA methylation analysis of neuroblastic tumors reveals clinically relevant epigenetic events and large-scale epigenomic alterations localized to telomeric regions. Int J Cancer 2010; 128: 2296-305.
    • (2010) Int J Cancer , vol.128 , pp. 2296-2305
    • Buckley, P.G.1    Das, S.2    Bryan, K.3    Watters, K.M.4    Alcock, L.5    Koster, J.6
  • 6
    • 84879416173 scopus 로고    scopus 로고
    • Modulation of neuroblastoma disease pathogenesis by an extensive network of epigenetically regulated microRNAs
    • Das S, Bryan K, Buckley PG, Piskareva O, Bray IM, Foley N, et al. Modulation of neuroblastoma disease pathogenesis by an extensive network of epigenetically regulated microRNAs. Oncogene 2013; 32: 2927-36.
    • (2013) Oncogene , vol.32 , pp. 2927-2936
    • Das, S.1    Bryan, K.2    Buckley, P.G.3    Piskareva, O.4    Bray, I.M.5    Foley, N.6
  • 7
    • 78049265812 scopus 로고    scopus 로고
    • MicroRNA mediates DNA demethylation events triggered by retin-oic acid during neuroblastoma cell differentiation
    • Das S, Foley N, Bryan K, Watters KM, Bray I, Murphy DM, et al. MicroRNA mediates DNA demethylation events triggered by retin-oic acid during neuroblastoma cell differentiation. Cancer Res 2010; 70: 7874-81.
    • (2010) Cancer Res , vol.70 , pp. 7874-7881
    • Das, S.1    Foley, N.2    Bryan, K.3    Watters, K.M.4    Bray, I.5    Murphy, D.M.6
  • 8
    • 42449129710 scopus 로고    scopus 로고
    • Positional gene enrichment analysis of gene sets for high-resolution identification of overrepresented chromosomal regions
    • De Preter K, Barriot R, Speleman F, Vandesompele J, Moreau Y. Positional gene enrichment analysis of gene sets for high-resolution identification of overrepresented chromosomal regions. Nucleic Acid Res 2008; 36: e43.
    • (2008) Nucleic Acid Res , vol.36 , pp. e43
    • De Preter, K.1    Barriot, R.2    Speleman, F.3    Vandesompele, J.4    Moreau, Y.5
  • 11
    • 77950187447 scopus 로고    scopus 로고
    • Dnmt1 and Dnmt3a maintain DNA methylation and regulate synaptic function in adult forebrain neurons
    • Feng J, Zhou Y, Campbell SL, Le T, Li E, Sweatt JD, et al. Dnmt1 and Dnmt3a maintain DNA methylation and regulate synaptic function in adult forebrain neurons. Nat Neurosci 2010; 13: 423-30.
    • (2010) Nat Neurosci , vol.13 , pp. 423-430
    • Feng, J.1    Zhou, Y.2    Campbell, S.L.3    Le Li T, E.4    Sweatt, J.D.5
  • 13
    • 80053270332 scopus 로고    scopus 로고
    • Neuronal activity modifies the DNA methylation landscape in the adult brain
    • Guo JU, Ma DK, Mo H, Ball MP, Jang MH, Bonaguidi MA, et al. Neuronal activity modifies the DNA methylation landscape in the adult brain. Nat Neurosci 2011a; 14: 1345-51.
    • (2011) Nat Neurosci , vol.14 , pp. 1345-1351
    • Guo, J.U.1    Ma, D.K.2    Mo, H.3    Ball, M.P.4    Jang, M.H.5    Bonaguidi, M.A.6
  • 14
    • 79955538247 scopus 로고    scopus 로고
    • Hydroxylation of 5-methylcytosine by TET1 promotes active DNA demethylation in the adult brain
    • Guo JU, Su Y, Zhong C, Ming GL, Song H. Hydroxylation of 5-methylcytosine by TET1 promotes active DNA demethylation in the adult brain. Cell 2011b; 145: 423-34.
    • (2011) Cell , vol.145 , pp. 423-434
    • Guo, J.U.1    Su, Y.2    Zhong, C.3    Ming, G.L.4    Song, H.5
  • 15
    • 84896399068 scopus 로고    scopus 로고
    • MicroRNA and epilepsy: Profiling, functions and potential clinical applications
    • Henshall DC. MicroRNA and epilepsy: profiling, functions and potential clinical applications. Curr Opin Neurol 2014; 27: 199-205.
    • (2014) Curr Opin Neurol , vol.27 , pp. 199-205
    • Henshall, D.C.1
  • 16
    • 0032842207 scopus 로고    scopus 로고
    • Relationship between seizure-induced transcription of the DNA damage-inducible gene GADD45, DNA fragmentation, and neuronal death in focally evoked limbic epilepsy
    • Henshall DC, Sinclair J, Simon RP. Relationship between seizure-induced transcription of the DNA damage-inducible gene GADD45, DNA fragmentation, and neuronal death in focally evoked limbic epilepsy. J Neurochem 1999; 73: 1573-83.
    • (1999) J Neurochem , vol.73 , pp. 1573-1583
    • Henshall, D.C.1    Sinclair, J.2    Simon, R.P.3
  • 17
    • 61449172037 scopus 로고    scopus 로고
    • Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources
    • Huang da W, Sherman BT, Lempicki RA. Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources. Nat Prot 2009; 4: 44-57.
    • (2009) Nat Prot , vol.4 , pp. 44-57
    • Huang Da, W.1    Sherman, B.T.2    Lempicki, R.A.3
  • 18
    • 0037372003 scopus 로고    scopus 로고
    • Epigenetic regulation of gene expression: How the genome integrates intrinsic and environmental signals
    • Jaenisch R, Bird A. Epigenetic regulation of gene expression: how the genome integrates intrinsic and environmental signals. Nat Genet 2003; 33 (Suppl): 245-54.
    • (2003) Nat Genet , vol.33 , pp. 245-254
    • Jaenisch, R.1    Bird, A.2
  • 19
    • 84933178818 scopus 로고    scopus 로고
    • Antagomirs targeting microRNA-134 increase hippocampal pyramidal neuron spine volume in vivo and protect against pilocarpine-induced status epi-lepticus
    • Advance Access published on May 30, 2014
    • Jimenez-Mateos EM, Engel T, Merino-Serrais P, Fernaud-Espinosa I, Rodriguez-Alvarez N, Reynolds J, et al. Antagomirs targeting microRNA-134 increase hippocampal pyramidal neuron spine volume in vivo and protect against pilocarpine-induced status epi-lepticus. Brain Struct Funct 2014. Advance Access published on May 30, 2014, doi:10.1007/s00429-014-0798-5.
    • (2014) Brain Struct Funct
    • Jimenez-Mateos, E.M.1    Engel, T.2    Merino-Serrais, P.3    Fernaud-Espinosa, I.4    Rodriguez-Alvarez, N.5    Reynolds, J.6
  • 22
    • 84884471932 scopus 로고    scopus 로고
    • TET1 controls CNS 5-methylcytosine hydroxylation, active DNA demethylation, gene transcription, and memory formation
    • Kaas GA, Zhong C, Eason DE, Ross DL, Vachhani RV, Ming GL, et al. TET1 controls CNS 5-methylcytosine hydroxylation, active DNA demethylation, gene transcription, and memory formation. Neuron 2013; 79: 1086-93.
    • (2013) Neuron , vol.79 , pp. 1086-1093
    • Kaas, G.A.1    Zhong, C.2    Eason, D.E.3    Ross, D.L.4    Vachhani, R.V.5    Ming, G.L.6
  • 23
    • 84865618700 scopus 로고    scopus 로고
    • Genome-wide microRNA profiling of human temporal lobe epilepsy identifies modulators of the immune response
    • Kan AA, van Erp S, Derijck AA, de Wit M, Hessel EV, O'Duibhir E, et al. Genome-wide microRNA profiling of human temporal lobe epilepsy identifies modulators of the immune response. Cell Mol Life Sci 2012; 69: 3127-45.
    • (2012) Cell Mol Life Sci , vol.69 , pp. 3127-3145
    • Kan, A.A.1    Van Erp, S.2    Derijck, A.A.3    De Wit, M.4    Hessel, E.V.5    O'Duibhir, E.6
  • 24
    • 36448973787 scopus 로고    scopus 로고
    • Idiographica: A general-purpose web application to build idiograms on-demand for human, mouse and rat
    • Kin T, Ono Y. Idiographica: a general-purpose web application to build idiograms on-demand for human, mouse and rat. Bioinformatics 2007; 23: 2945-6.
    • (2007) Bioinformatics , vol.23 , pp. 2945-2946
    • Kin, T.1    Ono, Y.2
  • 25
    • 79960108626 scopus 로고    scopus 로고
    • The methylation hypothesis: Do epigenetic chro-matin modifications play a role in epileptogenesis?
    • Kobow K, Blumcke I. The methylation hypothesis: do epigenetic chro-matin modifications play a role in epileptogenesis? Epilepsia 2011; 52 (Suppl 4): 15-9.
    • (2011) Epilepsia , vol.52 , pp. 15-19
    • Kobow, K.1    Blumcke, I.2
  • 26
    • 64449087253 scopus 로고    scopus 로고
    • Increased reelin promoter methylation is associated with granule cell dispersion in human temporal lobe epilepsy
    • Kobow K, Jeske I, Hildebrandt M, Hauke J, Hahnen E, Buslei R, et al. Increased reelin promoter methylation is associated with granule cell dispersion in human temporal lobe epilepsy. J Neuropathol Exp Neurol 2009; 68: 356-64.
    • (2009) J Neuropathol Exp Neurol , vol.68 , pp. 356-364
    • Kobow, K.1    Jeske, I.2    Hildebrandt, M.3    Hauke, J.4    Hahnen, E.5    Buslei, R.6
  • 31
    • 84870259644 scopus 로고    scopus 로고
    • Epileptogenesis: Can the science of epigenetics give us answers?
    • Lubin FD. Epileptogenesis: can the science of epigenetics give us answers? Epilepsy Curr 2012; 12: 105-10.
    • (2012) Epilepsy Curr , vol.12 , pp. 105-110
    • Lubin, F.D.1
  • 32
    • 60749094831 scopus 로고    scopus 로고
    • Neuronal activity-induced Gadd45b promotes epigenetic DNA demethylation and adult neurogenesis
    • Ma DK, Jang MH, Guo JU, Kitabatake Y, Chang ML, Pow-Anpongkul N, et al. Neuronal activity-induced Gadd45b promotes epigenetic DNA demethylation and adult neurogenesis. Science 2009; 323: 1074-7.
    • (2009) Science , vol.323 , pp. 1074-1077
    • Ma, D.K.1    Jang, M.H.2    Guo, J.U.3    Kitabatake, Y.4    Chang, M.L.5    Pow-Anpongkul, N.6
  • 33
    • 84896739948 scopus 로고    scopus 로고
    • Single cell genomics: Advances and future perspectives
    • Macaulay IC, Voet T. Single cell genomics: advances and future perspectives. PLoS Genet 2014; 10: e1004126.
    • (2014) PLoS Genet , vol.10 , pp. e1004126
    • Macaulay, I.C.1    Voet, T.2
  • 34
    • 0038062630 scopus 로고    scopus 로고
    • Sox1-deficient mice suffer from epilepsy associated with abnormal ventral forebrain development and olfactory cortex hyperexcitability
    • Malas S, Postlethwaite M, Ekonomou A, Whalley B, Nishiguchi S, Wood H, et al. Sox1-deficient mice suffer from epilepsy associated with abnormal ventral forebrain development and olfactory cortex hyperexcitability. Neuroscience 2003; 119: 421-32.
    • (2003) Neuroscience , vol.119 , pp. 421-432
    • Malas, S.1    Postlethwaite, M.2    Ekonomou, A.3    Whalley, B.4    Nishiguchi, S.5    Wood, H.6
  • 35
    • 84866157204 scopus 로고    scopus 로고
    • Reduced mature microRNA levels in association with dicer loss in human temporal lobe epilepsy with hippocampal sclerosis
    • McKiernan RC, Jimenez-Mateos EM, Bray I, Engel T, Brennan GP, Sano T, et al. Reduced mature microRNA levels in association with dicer loss in human temporal lobe epilepsy with hippocampal sclerosis. PloS One 2012; 7: e35921.
    • (2012) PloS One , vol.7 , pp. e35921
    • McKiernan, R.C.1    Jimenez-Mateos, E.M.2    Bray, I.3    Engel, T.4    Brennan, G.P.5    Sano, T.6
  • 37
    • 84884176211 scopus 로고    scopus 로고
    • Investigating gene promoter methylation in a mouse model of status epilepticus
    • Miller-Delaney SF, Das S, Stallings RL, Henshall DC. Investigating gene promoter methylation in a mouse model of status epilepticus. Meth Mol Biol 2013; 1067: 87-101.
    • (2013) Meth Mol Biol , vol.1067 , pp. 87-101
    • Miller-Delaney, S.F.1    Das, S.2    Stallings, R.L.3    Henshall, D.C.4
  • 38
    • 33847614418 scopus 로고    scopus 로고
    • Covalent modification of DNA regulates memory formation
    • Miller CA, Sweatt JD. Covalent modification of DNA regulates memory formation. Neuron 2007; 53: 857-69.
    • (2007) Neuron , vol.53 , pp. 857-869
    • Miller, C.A.1    Sweatt, J.D.2
  • 39
    • 79551568775 scopus 로고    scopus 로고
    • A microRNA-dependent program controls p53-in-dependent survival and chemosensitivity in human and murine squa-mous cell carcinoma
    • Ory B, Ramsey MR, Wilson C, Vadysirisack DD, Forster N, Rocco JW, et al. A microRNA-dependent program controls p53-in-dependent survival and chemosensitivity in human and murine squa-mous cell carcinoma. J Clin Invest 2011; 121: 809-20.
    • (2011) J Clin Invest , vol.121 , pp. 809-820
    • Ory, B.1    Ramsey, M.R.2    Wilson, C.3    Vadysirisack, D.D.4    Forster, N.5    Rocco, J.W.6
  • 40
    • 78751488401 scopus 로고    scopus 로고
    • Mechanisms of epileptogenesis and potential treatment targets
    • Pitkanen A, Lukasiuk K. Mechanisms of epileptogenesis and potential treatment targets. Lancet Neurol 2011; 10: 173-86.
    • (2011) Lancet Neurol , vol.10 , pp. 173-186
    • Pitkanen, A.1    Lukasiuk, K.2
  • 41
    • 77952887283 scopus 로고    scopus 로고
    • Epigenetic mechanisms underlying human epileptic disorders and the process of epileptogenesis
    • Qureshi IA, Mehler MF. Epigenetic mechanisms underlying human epileptic disorders and the process of epileptogenesis. Neurobiol Dis 2010; 39: 53-60.
    • (2010) Neurobiol Dis , vol.39 , pp. 53-60
    • Qureshi, I.A.1    Mehler, M.F.2
  • 42
    • 84864126183 scopus 로고    scopus 로고
    • Emerging roles of non-coding RNAs in brain evolution, development, plasticity and disease
    • Qureshi IA, Mehler MF. Emerging roles of non-coding RNAs in brain evolution, development, plasticity and disease. Nat Rev Neurosci 2012; 13: 528-41.
    • (2012) Nat Rev Neurosci , vol.13 , pp. 528-541
    • Qureshi, I.A.1    Mehler, M.F.2
  • 43
    • 22844457491 scopus 로고    scopus 로고
    • DNA methylation and human disease
    • Robertson KD. DNA methylation and human disease. Nat Rev Genet 2005; 6: 597-610.
    • (2005) Nat Rev Genet , vol.6 , pp. 597-610
    • Robertson, K.D.1
  • 45
    • 84880935246 scopus 로고    scopus 로고
    • Status epilepticus triggers early and late alterations in brain-derived neurotrophic factor and NMDA glutamate receptor Grin2b DNA methylation levels in the hippocampus
    • Ryley Parrish R, Albertson AJ, Buckingham SC, Hablitz JJ, Mascia KL, Davis Haselden W, et al. Status epilepticus triggers early and late alterations in brain-derived neurotrophic factor and NMDA glutamate receptor Grin2b DNA methylation levels in the hippocampus. Neuroscience 2013; 248C: 602-19.
    • (2013) Neuroscience , vol.248 C , pp. 602-619
    • Ryley Parrish, R.1    Albertson, A.J.2    Buckingham, S.C.3    Hablitz, J.J.4    Mascia, K.L.5    Davis Haselden, W.6
  • 48
    • 66949168048 scopus 로고    scopus 로고
    • A functional screen implicates microRNA-138-dependent regulation of the depalmitoylation enzyme APT1 in dendritic spine morphogenesis
    • Siegel G, Obernosterer G, Fiore R, Oehmen M, Bicker S, Christensen M, et al. A functional screen implicates microRNA-138-dependent regulation of the depalmitoylation enzyme APT1 in dendritic spine morphogenesis. Nat Cell Biol 2009; 11: 705-16.
    • (2009) Nat Cell Biol , vol.11 , pp. 705-716
    • Siegel, G.1    Obernosterer, G.2    Fiore, R.3    Oehmen, M.4    Bicker, S.5    Christensen, M.6
  • 51
    • 79958020894 scopus 로고    scopus 로고
    • Deletion of astroglial dicer causes non-cell-autonomous neuronal dysfunction and degeneration
    • Tao J, Wu H, Lin Q, Wei W, Lu XH, Cantle JP, et al. Deletion of astroglial dicer causes non-cell-autonomous neuronal dysfunction and degeneration. J Neurosci 2011; 31: 8306-19.
    • (2011) J Neurosci , vol.31 , pp. 8306-8319
    • Tao, J.1    Wu, H.2    Lin, Q.3    Wei, W.4    Lu, X.H.5    Cantle, J.P.6
  • 52
    • 84900862090 scopus 로고    scopus 로고
    • The hidden genetics of epilepsy-A clinically important new paradigm
    • Thomas RH, Berkovic SF. The hidden genetics of epilepsy-a clinically important new paradigm. Nat Rev Neurol 2014; 10: 283-92.
    • (2014) Nat Rev Neurol , vol.10 , pp. 283-292
    • Thomas, R.H.1    Berkovic, S.F.2
  • 53
    • 70449725209 scopus 로고    scopus 로고
    • Epigenetic mechanisms in neurological diseases: Genes, syndromes, and therapies
    • Urdinguio RG, Sanchez-Mut JV, Esteller M. Epigenetic mechanisms in neurological diseases: genes, syndromes, and therapies. Lancet Neurol 2009; 8: 1056-72.
    • (2009) Lancet Neurol , vol.8 , pp. 1056-1072
    • Urdinguio, R.G.1    Sanchez-Mut, J.V.2    Esteller, M.3
  • 56
    • 84890540447 scopus 로고    scopus 로고
    • Demethylation of miR-9-3 and miR-193a genes suppresses proliferation and promotes apoptosis in non-small cell lung cancer cell lines
    • Wang J, Yang B, Han L, Li X, Tao H, Zhang S, et al. Demethylation of miR-9-3 and miR-193a genes suppresses proliferation and promotes apoptosis in non-small cell lung cancer cell lines. Cell Physiol Biochem 2013; 32: 1707-19.
    • (2013) Cell Physiol Biochem , vol.32 , pp. 1707-1719
    • Wang, J.1    Yang, B.2    Han, L.3    Li, X.4    Tao, H.5    Zhang, S.6
  • 57
    • 0029917254 scopus 로고    scopus 로고
    • Pathological grading system for hippocampal sclerosis: Correlation with magnetic resonance imaging-based volume measurements of the hippocampus
    • Watson C, Nielsen SL, Cobb C, Burgerman R, Williamson B. Pathological grading system for hippocampal sclerosis: correlation with magnetic resonance imaging-based volume measurements of the hippocampus. J Epilepsy 1996; 9: 56-64.
    • (1996) J Epilepsy , vol.9 , pp. 56-64
    • Watson, C.1    Nielsen, S.L.2    Cobb, C.3    Burgerman, R.4    Williamson, B.5
  • 58
    • 3042685585 scopus 로고    scopus 로고
    • Mesial temporal lobe epilepsy with hippocampal sclerosis
    • ILAE Commission Report.
    • Wieser HG. ILAE Commission Report. Mesial temporal lobe epilepsy with hippocampal sclerosis. Epilepsia 2004; 45: 695-714.
    • (2004) Epilepsia , vol.45 , pp. 695-714
    • Wieser, H.G.1
  • 60
    • 84866179730 scopus 로고    scopus 로고
    • Increased expression of DNA methyltransferase 1 and 3a in human temporal lobe epilepsy
    • Zhu Q, Wang L, Zhang Y, Zhao FH, Luo J, Xiao Z, et al. Increased expression of DNA methyltransferase 1 and 3a in human temporal lobe epilepsy. J Mol Neurosci 2012; 46: 420-6.
    • (2012) J Mol Neurosci , vol.46 , pp. 420-426
    • Zhu, Q.1    Wang, L.2    Zhang, Y.3    Zhao, F.H.4    Luo, J.5    Xiao, Z.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.