The role of dihydroorotate dehydrogenase in apoptosis induction in response to inhibition of the mitochondrial respiratory Chain complex III

Acta Naturae

Volumn 6, Issue 20, 2014, Pages 69-75

  Khutornenko, A A ^a   Dalina, A A ^b   Chernyak, B V ^a   Chumakov, P M ^b   Evstafieva, A G ^a  

^a MOSCOW STATE UNIVERSITY   (Russian Federation)

^b ENGELHARDT INSTITUTE OF MOLECULAR BIOLOGY   (Russian Federation)

Author keywords

Apoptosis; de novo pyrimidine biosynthesis; Dihydroorotate dehydrogenase; Mitochondrial respiratory chain; p53 tumor suppressor

Indexed keywords

EID: 84898901267     PISSN: 20758251     EISSN: None     Source Type: Journal    
DOI: 10.32607/20758251-2014-6-1-69-75     Document Type: Article

References (15)

1. McBride H.M., Neuspiel M., Wasiak S.//Curr. Biol. 2006. Vol.16. No 5. No. 551-560.
2. Meunier B., Fisher N., Ransac S., Mazat J.P., Brasseur G.//Biochim. Biophys. Acta. 2013. V. 1827. No 11-12, P. 1346-1361.
3. Trifunovic A., Larsson N.-G.//J. Intern. Med. 2008. V. 263. No 2. No.167-178.
4. Chumakov P.M.//Biochemistry (Mosc). 2007. V. 72. No 13. P.1399-1421.
5. Khutornenko A.A., Roudko V.V., Chernyak B.V., Vartapetian A.B., Chumakov P.M., Evstafieva A.G.//Proc. Natl. Acad. Sci. U S A. 2010. V.107. No 29. No. 12828-12833.
6. Evans D.R., Guy H.I.//J. Biol. Chem. 2004. V. 279. No 32. No. 33035-33038.
7. Sukhacheva E.A., Evstafieva A.G., Fateeva T.V., Shakulov V.R., Efimova N.A., Karapetian R.N., Rubtsov Y.P., Vartapetian A.B.//J. Immunol. Methods. 2002. V. 266. No1-2. No. 185-196.
8. Guryanova O.A., Makhanov M., Chenchik A.A., Chumakov P.M., Frolova E.I.//Mol. Biol. (Mosk). 2006. V. 40. No 3. P. 396-405.
9. Painter H.J., Morrisey J.M., Mather M.W., Vaidya A.B.//Nature. 2007. V. 446. No 1. No. 88-91.
10. Baumann P., Mandl-Weber S., Völkl A., Adam C., Bumeder I., Oduncu F., Schmidmaier R.//Mol. Cancer Ther. 2009. V. 8. No 3. No. 366-375.
11. Hail N. Jr., Chen P., Bushman L.R.//Neoplasia. 2010. V. 12. No 4. No. 464-475.
12. Hail N. Jr, Chen P., Kepa J.J., Bushman L.R.//Apoptosis. 2012. V. 17. No 2. No. 258-268.
13. Agarwal M.L., Agarwal A., Taylor W.R., Chernova O., Sharma Y., Stark G.R.//Proc. Natl. Acad. Sci. U S A. 1998. V. 95. No 25. No. 14775-14780.
14. Agarwal M.K., Hastak K., Jackson M.W., Breit S.N., Stark G.R., Agarwal M.L.//Proc. Natl. Acad. Sci. U S A. 2006. V. 103. No 44. No. 16278-16283.
15. Hastak K., Paul R.K., Agarwal M.K., Thakur V.S., Amin A.R., Agrawal S., Sramkoski R.M., Jacobberger J.W., Jackson M.W., Stark G.R., Agarwal M.L.//Proc. Natl. Acad. Sci. USA. 2008. V. 105. No 17. No. 6314-6319.