A mechanistic, multiscale mathematical model of immunogenicity for therapeutic proteins: Part 1 - Theoretical model

CPT: Pharmacometrics and Systems Pharmacology

Volumn 3, Issue 9, 2014, Pages

  Chen, X ^a   Hickling, T P ^a   Vicini, P ^a  

^a PFIZER INC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

EPITOPE;

ADAPTIVE IMMUNITY; ANTIGEN PRESENTATION; B LYMPHOCYTE ACTIVATION; BINDING AFFINITY; CELL DIFFERENTIATION; CELL KINETICS; CELL PROLIFERATION; CONFERENCE PAPER; CONTROLLED STUDY; DENDRITIC CELL; HELPER CELL; HUMAN; HUMORAL IMMUNITY; IMMUNOGENICITY; IN VITRO STUDY; IN VIVO STUDY; MAJOR HISTOCOMPATIBILITY COMPLEX; MATHEMATICAL MODEL; MEMORY T LYMPHOCYTE; PRIORITY JOURNAL; SENSITIVITY ANALYSIS; T LYMPHOCYTE ACTIVATION; THEORETICAL MODEL;

EID: 84927915266     PISSN: None     EISSN: 21638306     Source Type: Journal    
DOI: 10.1038/psp.2014.30     Document Type: Conference Paper

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