Persistence of sulfadoxine-pyrimethamine resistance despite reduction of drug pressure in Malawi

Journal of Infectious Diseases

Volumn 212, Issue 5, 2015, Pages 694-701

  Artimovich, Elena ^a   Schneider, Kristan ^d   Taylor, Terrie E ^e   Kublin, James G ^b   Dzinjalamala, Fraction K ^e   Escalante, Ananias A ^c   Plowe, Christopher V ^a   Laufer, Miriam K ^a   Takala Harrison, Shannon ^a  

^a University of Maryland School of Medicine Center for Vaccine Development   (United States)

^b USA   (United States)

^c ARIZONA STATE UNIVERSITY   (United States)

^d UNIVERSITY OF APPLIED SCIENCES MITTWEIDA   (Germany)

^e UNIVERSITY OF MALAWI   (Malawi)

Author keywords

DHFR; DHPS; Malaria; Pyrosequencing; Resistance; Selective sweeps; Sulfadoxine pyrimethamine

Indexed keywords

PYRIMETHAMINE PLUS SULFADOXINE; ANTIMALARIAL AGENT; DIHYDROFOLATE REDUCTASE; DIHYDROPTEROATE SYNTHASE; DRUG COMBINATION; FANASIL, PYRIMETHAMINE DRUG COMBINATION; PROTOZOAL DNA; PROTOZOAL PROTEIN; PYRIMETHAMINE; SULFADOXINE;

ANTIMALARIAL DRUG RESISTANCE; ARTICLE; CODON; CONTROLLED STUDY; GENE LOCUS; GENETIC VARIABILITY; GENOTYPE; HAPLOTYPE; HETEROZYGOSITY; HUMAN; MALARIA; MALAWI; MICROSATELLITE MARKER; NONHUMAN; PRIORITY JOURNAL; DRUG COMBINATION; DRUG EFFECTS; DRUG RESISTANCE; GENE FREQUENCY; GENETIC SELECTION; GENETICS; MALARIA, FALCIPARUM; MISSENSE MUTATION; PARASITOLOGY; PLASMODIUM FALCIPARUM;

ANTIMALARIALS; DIHYDROPTEROATE SYNTHASE; DNA, PROTOZOAN; DRUG COMBINATIONS; DRUG RESISTANCE; GENE FREQUENCY; GENOTYPE; HAPLOTYPES; HUMANS; MALARIA, FALCIPARUM; MALAWI; MUTATION, MISSENSE; PLASMODIUM FALCIPARUM; PROTOZOAN PROTEINS; PYRIMETHAMINE; SELECTION, GENETIC; SULFADOXINE; TETRAHYDROFOLATE DEHYDROGENASE;

EID: 84927790743     PISSN: 00221899     EISSN: 15376613     Source Type: Journal    
DOI: 10.1093/infdis/jiv078     Document Type: Article

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