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Volumn 29, Issue 5, 2015, Pages 283-291

An update on the pharmacogenetics of treating hypertension

Author keywords

[No Author keywords available]

Indexed keywords

ANGIOTENSIN RECEPTOR ANTAGONIST; ANTIHYPERTENSIVE AGENT; BETA ADRENERGIC RECEPTOR BLOCKING AGENT; CALCIUM CHANNEL BLOCKING AGENT; DIPEPTIDYL CARBOXYPEPTIDASE INHIBITOR; DIURETIC AGENT;

EID: 84927759893     PISSN: 09509240     EISSN: 14765527     Source Type: Journal    
DOI: 10.1038/jhh.2014.76     Document Type: Review
Times cited : (33)

References (51)
  • 1
    • 77951124073 scopus 로고    scopus 로고
    • Antihypertensive drug therapy and blood pressure control in men and women: An international perspective
    • Thoenes M, Neuberger HR, Volpe M, Khan BV, Kirch W, Böhm M. Antihypertensive drug therapy and blood pressure control in men and women: an international perspective. J Hum Hypertens 2010; 24(5): 336-344.
    • (2010) J Hum Hypertens , vol.24 , Issue.5 , pp. 336-344
    • Thoenes, M.1    Neuberger, H.R.2    Volpe, M.3    Khan, B.V.4    Kirch, W.5    Böhm, M.6
  • 2
    • 84862579604 scopus 로고    scopus 로고
    • Advancing management of hypertension through pharmacoge-nomics
    • Johnson JA. Advancing management of hypertension through pharmacoge-nomics. Ann Med 2012; 44(Suppl 1): S17-S22.
    • (2012) Ann Med , vol.44 , pp. S17-S22
    • Johnson, J.A.1
  • 3
    • 84888137548 scopus 로고    scopus 로고
    • Heritability analyses show visit-to-visit blood pressure variability reflects different pathological phenotypes in younger and older adults: Evidence from UK twins
    • Menni C, Mangino M, Zhang F, Clement G, Snieder H, Padmanabhan S et al. Heritability analyses show visit-to-visit blood pressure variability reflects different pathological phenotypes in younger and older adults: evidence from UK twins. J Hypertens 2013; 31(12): 2356-2361.
    • (2013) J Hypertens , vol.31 , Issue.12 , pp. 2356-2361
    • Menni, C.1    Mangino, M.2    Zhang, F.3    Clement, G.4    Snieder, H.5    Padmanabhan, S.6
  • 4
    • 84857640087 scopus 로고    scopus 로고
    • Between candidate genes and whole genomes: Time for alternative approaches in blood pressure genetics
    • Basson J, Simino J, Rao DC. Between candidate genes and whole genomes: time for alternative approaches in blood pressure genetics. Curr Hypertens Rep 2012; 14 (1): 46-61.
    • (2012) Curr Hypertens Rep , vol.14 , Issue.1 , pp. 46-61
    • Basson, J.1    Simino, J.2    Rao, D.C.3
  • 5
    • 84879808127 scopus 로고    scopus 로고
    • Advances in blood pressure genomics
    • Munroe PB, Barnes MR, Caulfield MJ. Advances in blood pressure genomics. Circ Res 2013; 112(10): 1365-1379.
    • (2013) Circ Res , vol.112 , Issue.10 , pp. 1365-1379
    • Munroe, P.B.1    Barnes, M.R.2    Caulfield, M.J.3
  • 6
    • 84875168008 scopus 로고    scopus 로고
    • Genes for blood pressure: An opportunity to understand hypertension
    • Ehret GB, Caulfield MJ. Genes for blood pressure: an opportunity to understand hypertension. Eur Heart J 2013; 34(13): 951-961.
    • (2013) Eur Heart J , vol.34 , Issue.13 , pp. 951-961
    • Ehret, G.B.1    Caulfield, M.J.2
  • 7
  • 8
    • 84876280954 scopus 로고    scopus 로고
    • The molecular basis of blood pressure variation
    • Toka HR, Koshy JM, Hariri A. The molecular basis of blood pressure variation. Pediatr Nephrol 2013; 28(3): 387-399.
    • (2013) Pediatr Nephrol , vol.28 , Issue.3 , pp. 387-399
    • Toka, H.R.1    Koshy, J.M.2    Hariri, A.3
  • 9
    • 84899417586 scopus 로고    scopus 로고
    • Clinical Pharmacogenetics Implementation Consortium Guidelines for HLA-B Genotype and Abacavir Dosing: 2014 update
    • Martin MA, Hoffman JM, Freimuth RR, Klein TE, Dong BJ, Pirmohamed M et al. Clinical Pharmacogenetics Implementation Consortium Guidelines for HLA-B Genotype and Abacavir Dosing: 2014 update. Clin Pharmacol Ther 2014; 95(5): 499-500.
    • (2014) Clin Pharmacol Ther , vol.95 , Issue.5 , pp. 499-500
    • Martin, M.A.1    Hoffman, J.M.2    Freimuth, R.R.3    Klein, T.E.4    Dong, B.J.5    Pirmohamed, M.6
  • 10
    • 84880453290 scopus 로고    scopus 로고
    • Pharmacogenomics in early-phase clinical development
    • Burt T, Dhillon S. Pharmacogenomics in early-phase clinical development. Pharmacogenomics 2013; 14(9): 1085-1097.
    • (2013) Pharmacogenomics , vol.14 , Issue.9 , pp. 1085-1097
    • Burt, T.1    Dhillon, S.2
  • 12
    • 79951809825 scopus 로고    scopus 로고
    • CPIC: Clinical Pharmacogenetics Implementation Consortium of the Pharmacogenomics Research Network
    • Relling MV, Klein TE. CPIC: Clinical Pharmacogenetics Implementation Consortium of the Pharmacogenomics Research Network. Clin Pharmacol Ther 2011; 89(3): 464-467.
    • (2011) Clin Pharmacol Ther , vol.89 , Issue.3 , pp. 464-467
    • Relling, M.V.1    Klein, T.E.2
  • 14
    • 49849084134 scopus 로고    scopus 로고
    • Genomic association analysis suggests chromosome 12 locus influencing antihypertensive response to thiazide diuretic
    • Turner ST, Bailey KR, Fridley BL, Chapman AB, Schwartz GL, Chai HS et al. Genomic association analysis suggests chromosome 12 locus influencing antihypertensive response to thiazide diuretic. Hypertension 2008; 52(2): 359-365.
    • (2008) Hypertension , vol.52 , Issue.2 , pp. 359-365
    • Turner, S.T.1    Bailey, K.R.2    Fridley, B.L.3    Chapman, A.B.4    Schwartz, G.L.5    Chai, H.S.6
  • 15
    • 84878251897 scopus 로고    scopus 로고
    • Association of chromosome 12 locus with antihypertensive response to hydrochlorothiazide may involve differential YEATS4 expression
    • Duarte JD, Turner ST, Tran B, Chapman AB, Bailey KR, Gong Y et al. Association of chromosome 12 locus with antihypertensive response to hydrochlorothiazide may involve differential YEATS4 expression. Pharmacogenomics J 2013; 13(3): 257-263.
    • (2013) Pharmacogenomics J , vol.13 , Issue.3 , pp. 257-263
    • Duarte, J.D.1    Turner, S.T.2    Tran, B.3    Chapman, A.B.4    Bailey, K.R.5    Gong, Y.6
  • 16
    • 84880932080 scopus 로고    scopus 로고
    • Genomic association analysis of common variants influencing antihypertensive response to hydrochlorothiazide
    • Turner ST, Boerwinkle E, O'Connell JR, Bailey KR, Gong Y, Chapman AB et al. Genomic association analysis of common variants influencing antihypertensive response to hydrochlorothiazide. Hypertension 2013; 62(2): 391-397.
    • (2013) Hypertension , vol.62 , Issue.2 , pp. 391-397
    • Turner, S.T.1    Boerwinkle, E.2    O'Connell, J.R.3    Bailey, K.R.4    Gong, Y.5    Chapman, A.B.6
  • 17
    • 78651273887 scopus 로고    scopus 로고
    • A functional variant of the NEDD4L gene is associated with beneficial treatment response with β-blockers and diuretics in hypertensive patients
    • Svensson-Färbom P, Wahlstrand B, Almgren P, Dahlberg J, Fava C, Kjeldsen S et al. A functional variant of the NEDD4L gene is associated with beneficial treatment response with β-blockers and diuretics in hypertensive patients. J Hypertens 2011; 29(2): 388-395.
    • (2011) J Hypertens , vol.29 , Issue.2 , pp. 388-395
    • Svensson-Färbom, P.1    Wahlstrand, B.2    Almgren, P.3    Dahlberg, J.4    Fava, C.5    Kjeldsen, S.6
  • 18
    • 84875226941 scopus 로고    scopus 로고
    • Association of variants in NEDD4L with blood pressure response and adverse cardiovascular outcomes in hypertensive patients treated with thiazide diuretics
    • McDonough CW, Burbage SE, Duarte JD, Gong Y, Langaee TY, Turner ST et al. Association of variants in NEDD4L with blood pressure response and adverse cardiovascular outcomes in hypertensive patients treated with thiazide diuretics. J Hypertens 2013; 31(4): 698-704.
    • (2013) J Hypertens , vol.31 , Issue.4 , pp. 698-704
    • McDonough, C.W.1    Burbage, S.E.2    Duarte, J.D.3    Gong, Y.4    Langaee, T.Y.5    Turner, S.T.6
  • 19
    • 84873913555 scopus 로고    scopus 로고
    • Hypertension susceptibility loci and blood pressure response to anti-hypertensives: Results from the pharmacogenomic evaluation of antihypertensive responses study
    • Gong Y, McDonough CW, Wang Z, Hou W, Cooper-DeHoff RM, Langaee TY et al. Hypertension susceptibility loci and blood pressure response to anti-hypertensives: results from the pharmacogenomic evaluation of antihypertensive responses study. Circ Cardiovasc Genet 2012; 5(6): 686-691.
    • (2012) Circ Cardiovasc Genet , vol.5 , Issue.6 , pp. 686-691
    • Gong, Y.1    McDonough, C.W.2    Wang, Z.3    Hou, W.4    Cooper-Dehoff, R.M.5    Langaee, T.Y.6
  • 20
    • 0037340242 scopus 로고    scopus 로고
    • ACE and alpha-adducin polymorphism as markers of individual response to diuretic therapy
    • Sciarrone MT, Stella P, Barlassina C, Manunta P, Lanzani C, Bianchi G et al. ACE and alpha-adducin polymorphism as markers of individual response to diuretic therapy. Hypertension 2003; 41(3): 398-403.
    • (2003) Hypertension , vol.41 , Issue.3 , pp. 398-403
    • Sciarrone, M.T.1    Stella, P.2    Barlassina, C.3    Manunta, P.4    Lanzani, C.5    Bianchi, G.6
  • 21
    • 58549094102 scopus 로고    scopus 로고
    • Renin-angiotensin system and alpha-adducin gene polymorphisms and their relation to responses to antihypertensive drugs: Results from the GENRES study
    • Suonsyrjä T, Hannila-Handelberg T, Fodstad H, Donner K, Kontula K, Hiltunen TP. Renin-angiotensin system and alpha-adducin gene polymorphisms and their relation to responses to antihypertensive drugs: results from the GENRES study. Am J Hypertens 2009; 22(2): 169-175.
    • (2009) Am J Hypertens , vol.22 , Issue.2 , pp. 169-175
    • Suonsyrjä, T.1    Hannila-Handelberg, T.2    Fodstad, H.3    Donner, K.4    Kontula, K.5    Hiltunen, T.P.6
  • 22
    • 33847153057 scopus 로고    scopus 로고
    • Association between angiotensinogen, angiotensin II receptor genes, and blood pressure response to an angiotensin-converting enzyme inhibitor
    • Su X, Lee L, Li X, Lv J, Hu Y, Zhan S et al. Association between angiotensinogen, angiotensin II receptor genes, and blood pressure response to an angiotensin-converting enzyme inhibitor. Circulation 2007; 115(6): 725-732.
    • (2007) Circulation , vol.115 , Issue.6 , pp. 725-732
    • Su, X.1    Lee, L.2    Li, X.3    Lv, J.4    Hu, Y.5    Zhan, S.6
  • 23
    • 84893130762 scopus 로고    scopus 로고
    • Effect of NR3C2 genetic polymorphisms on the blood pressure response to enalapril treatment
    • Luo JQ, Wang LY, He FZ, Sun NL, Tang GF, Wen JG et al. Effect of NR3C2 genetic polymorphisms on the blood pressure response to enalapril treatment. Pharmacogenomics 2013; 15(2): 201-208.
    • (2013) Pharmacogenomics , vol.15 , Issue.2 , pp. 201-208
    • Luo, J.Q.1    Wang, L.Y.2    He, F.Z.3    Sun, N.L.4    Tang, G.F.5    Wen, J.G.6
  • 24
    • 80051791752 scopus 로고    scopus 로고
    • Pharmacogenetic predictors of angiotensin-converting enzyme inhibitor-induced cough: The role of ACE, ABO, and BDKRB2 genes
    • Mas S, Gassò P, Alvarez S, Ortiz J, Sotoca JM, Francino A et al. Pharmacogenetic predictors of angiotensin-converting enzyme inhibitor-induced cough: the role of ACE, ABO, and BDKRB2 genes. Pharmacogenet Genomics 2011; 21(9): 531-538.
    • (2011) Pharmacogenet Genomics , vol.21 , Issue.9 , pp. 531-538
    • Mas, S.1    Gassò, P.2    Alvarez, S.3    Ortiz, J.4    Sotoca, J.M.5    Francino, A.6
  • 25
    • 78650677591 scopus 로고    scopus 로고
    • Identification of genetic factors associated with susceptibility to angiotensin-converting enzyme inhibitors-induced cough
    • Grilo A, Sáez-Rosas MP, Santos-Morano J, Sánchez E, Moreno-Rey C, Real LM et al. Identification of genetic factors associated with susceptibility to angiotensin-converting enzyme inhibitors-induced cough. Pharmacogenet Genomics 2011; 21 (1): 10-17.
    • (2011) Pharmacogenet Genomics , vol.21 , Issue.1 , pp. 10-17
    • Grilo, A.1    Sáez-Rosas, M.P.2    Santos-Morano, J.3    Sánchez, E.4    Moreno-Rey, C.5    Real, L.M.6
  • 26
    • 0036959461 scopus 로고    scopus 로고
    • Association of polymorphisms of the renin-angiotensin system and bradykinin B2 receptor with ACE-inhibitor-related cough
    • Mukae S, Itoh S, Aoki S, Iwata T, Nishio K, Sato R et al. Association of polymorphisms of the renin-angiotensin system and bradykinin B2 receptor with ACE-inhibitor-related cough. J Hum Hypertens 2002; 16(12): 857-863.
    • (2002) J Hum Hypertens , vol.16 , Issue.12 , pp. 857-863
    • Mukae, S.1    Itoh, S.2    Aoki, S.3    Iwata, T.4    Nishio, K.5    Sato, R.6
  • 28
    • 25444454850 scopus 로고    scopus 로고
    • A variant in XPNPEP2 is associated with angioedema induced by angiotensin I-converting enzyme inhibitors
    • Duan QL, Nikpoor B, Dube MP, Molinaro G, Meijer IA, Dion P et al. A variant in XPNPEP2 is associated with angioedema induced by angiotensin I-converting enzyme inhibitors. Am J Hum Genet 2005; 77(4): 617-626.
    • (2005) Am J Hum Genet , vol.77 , Issue.4 , pp. 617-626
    • Duan, Q.L.1    Nikpoor, B.2    Dube, M.P.3    Molinaro, G.4    Meijer, I.A.5    Dion, P.6
  • 29
    • 80054713052 scopus 로고    scopus 로고
    • A functional XPNPEP2 promoter haplotype leads to reduced plasma amino-peptidase P and increased risk of ACE inhibitor-induced angioedema
    • Cilia La Corte AL, Carter AM, Rice GI, Duan QL, Rouleau GA, Adam A et al. A functional XPNPEP2 promoter haplotype leads to reduced plasma amino-peptidase P and increased risk of ACE inhibitor-induced angioedema. Hum Mutat 2011; 32(11): 1326-1331.
    • (2011) Hum Mutat , vol.32 , Issue.11 , pp. 1326-1331
    • Cilia La Corte, A.L.1    Carter, A.M.2    Rice, G.I.3    Duan, Q.L.4    Rouleau, G.A.5    Adam, A.6
  • 30
    • 84856292705 scopus 로고    scopus 로고
    • Individualised therapy of angiotensin converting enzyme (ACE) inhibitors in stable coronary artery disease: Overview of the primary results of the PERindopril GENEtic association (PERGENE) study
    • Brugts JJ, de Maat MP, Danser AH, Boersma E, Simoons ML. Individualised therapy of angiotensin converting enzyme (ACE) inhibitors in stable coronary artery disease: overview of the primary results of the PERindopril GENEtic association (PERGENE) study. Neth Heart J 2012; 20(1): 24-32.
    • (2012) Neth Heart J , vol.20 , Issue.1 , pp. 24-32
    • Brugts, J.J.1    De Maat, M.P.2    Danser, A.H.3    Boersma, E.4    Simoons, M.L.5
  • 31
    • 55449103747 scopus 로고    scopus 로고
    • Genetic variations of CYP2C9 in 724 Japanese individuals and their impact on the antihypertensive effects of losartan
    • Yin T, Maekawa K, Kamide K, Saito Y, Hanada H, Miyashita K et al. Genetic variations of CYP2C9 in 724 Japanese individuals and their impact on the antihypertensive effects of losartan. Hypertens Res 2008; 31(8): 1549-1557.
    • (2008) Hypertens Res , vol.31 , Issue.8 , pp. 1549-1557
    • Yin, T.1    Maekawa, K.2    Kamide, K.3    Saito, Y.4    Hanada, H.5    Miyashita, K.6
  • 32
    • 84861510163 scopus 로고    scopus 로고
    • Genomic association analysis identifies multiple loci influencing antihypertensive response to an angiotensin II receptor blocker
    • Turner ST, Bailey KR, Schwartz GL, Chapman AB, Chai HS, Boerwinkle E. Genomic association analysis identifies multiple loci influencing antihypertensive response to an angiotensin II receptor blocker. Hypertension 2012; 59(6): 1204-1211.
    • (2012) Hypertension , vol.59 , Issue.6 , pp. 1204-1211
    • Turner, S.T.1    Bailey, K.R.2    Schwartz, G.L.3    Chapman, A.B.4    Chai, H.S.5    Boerwinkle, E.6
  • 35
  • 36
    • 10044291653 scopus 로고    scopus 로고
    • Pharma-cokinetics and CYP2D6 genotypes do not predict metoprolol adverse events or efficacy in hypertension
    • Zineh I, Beitelshees AL, Gaedigk A, Walker JR, Pauly DF, Eberst K et al. Pharma-cokinetics and CYP2D6 genotypes do not predict metoprolol adverse events or efficacy in hypertension. Clin Pharmacol Ther 2004; 76(6): 536-544.
    • (2004) Clin Pharmacol Ther , vol.76 , Issue.6 , pp. 536-544
    • Zineh, I.1    Beitelshees, A.L.2    Gaedigk, A.3    Walker, J.R.4    Pauly, D.F.5    Eberst, K.6
  • 39
    • 79951809896 scopus 로고    scopus 로고
    • Cardiovascular pharmacogenomics of adrenergic receptor signaling: Clinical implications and future directions
    • Johnson JA, Liggett SB. Cardiovascular pharmacogenomics of adrenergic receptor signaling: clinical implications and future directions. Clin Pharmacol Ther 2011; 89 (3): 366-378.
    • (2011) Clin Pharmacol Ther , vol.89 , Issue.3 , pp. 366-378
    • Johnson, J.A.1    Liggett, S.B.2
  • 40
    • 77949602777 scopus 로고    scopus 로고
    • Haplotypes of the adrenergic system predict the blood pressure response to beta-blockers in women with essential hypertension
    • Filigheddu F, Argiolas G, Degortes S, Zaninello R, Frau F, Pitzoi S et al. Haplotypes of the adrenergic system predict the blood pressure response to beta-blockers in women with essential hypertension. Pharmacogenomics 2010; 11(3): 319-325.
    • (2010) Pharmacogenomics , vol.11 , Issue.3 , pp. 319-325
    • Filigheddu, F.1    Argiolas, G.2    Degortes, S.3    Zaninello, R.4    Frau, F.5    Pitzoi, S.6
  • 41
    • 84866549853 scopus 로고    scopus 로고
    • G protein receptor kinase 4 polymorphisms: β-blocker pharmacogenetics and treatment-related outcomes in hypertension
    • Vandell AG, Lobmeyer MT, Gawronski BE, Langaee TY, Gong Y, Gums JG et al. G protein receptor kinase 4 polymorphisms: β-blocker pharmacogenetics and treatment-related outcomes in hypertension. Hypertension 2012; 60(4): 957-964.
    • (2012) Hypertension , vol.60 , Issue.4 , pp. 957-964
    • Vandell, A.G.1    Lobmeyer, M.T.2    Gawronski, B.E.3    Langaee, T.Y.4    Gong, Y.5    Gums, J.G.6
  • 42
    • 84893208653 scopus 로고    scopus 로고
    • Genome-wide response to antihypertensive medication using home blood pressure measurements: A pilot study nested within the HOMED-BP study
    • Kamide K, Asayama K, Katsuya T, Ohkubo T, Hirose T, Inoue R et al. Genome-wide response to antihypertensive medication using home blood pressure measurements: a pilot study nested within the HOMED-BP study. Pharmacogenomics 2013; 14(14): 1709-1721.
    • (2013) Pharmacogenomics , vol.14 , Issue.14 , pp. 1709-1721
    • Kamide, K.1    Asayama, K.2    Katsuya, T.3    Ohkubo, T.4    Hirose, T.5    Inoue, R.6
  • 43
    • 34547919927 scopus 로고    scopus 로고
    • KCNMB1 genotype influences response to verapamil SR and adverse outcomes in the INternational VErapamil SR/Trandolapril STudy (INVEST)
    • Beitelshees AL, Gong Y, Wang D, Schork NJ, Cooper-Dehoff RM, Langaee TY et al. KCNMB1 genotype influences response to verapamil SR and adverse outcomes in the INternational VErapamil SR/Trandolapril STudy (INVEST). Pharmacogenet Genomics 2007; 17(9): 719-729.
    • (2007) Pharmacogenet Genomics , vol.17 , Issue.9 , pp. 719-729
    • Beitelshees, A.L.1    Gong, Y.2    Wang, D.3    Schork, N.J.4    Cooper-Dehoff, R.M.5    Langaee, T.Y.6
  • 44
  • 45
    • 84861094619 scopus 로고    scopus 로고
    • Pharmacogenetic implications for eight common blood pressure-associated single-nucleotide polymorphisms
    • Hamrefors V, Sjögren M, Almgren P, Wahlstrand B, Kjeldsen S, Hedner T et al. Pharmacogenetic implications for eight common blood pressure-associated single-nucleotide polymorphisms. J Hypertens 2012; 30(6): 1151-1160.
    • (2012) J Hypertens , vol.30 , Issue.6 , pp. 1151-1160
    • Hamrefors, V.1    Sjögren, M.2    Almgren, P.3    Wahlstrand, B.4    Kjeldsen, S.5    Hedner, T.6
  • 46
    • 27644538062 scopus 로고    scopus 로고
    • Cardiovascular outcome in treated hypertensive patients with responder, masked, false resistant, and true resistant hypertension
    • Pierdomenico SD, Lapenna D, Bucci A, Di Tommaso R, Di Mascio R, Manente BM et al. Cardiovascular outcome in treated hypertensive patients with responder, masked, false resistant, and true resistant hypertension. Am J Hypertens 2005; 18 (11): 1422-1428.
    • (2005) Am J Hypertens , vol.18 , Issue.11 , pp. 1422-1428
    • Pierdomenico, S.D.1    Lapenna, D.2    Bucci, A.3    Di Tommaso, R.4    Di Mascio, R.5    Manente, B.M.6
  • 47
    • 84888861305 scopus 로고    scopus 로고
    • Genetic and Adverse Health Outcome Associations with Treatment Resistant Hypertension in GenHAT
    • Lynch AI, Irvin MR, Davis BR, Ford CE, Eckfeldt JH, Arnett DK. Genetic and Adverse Health Outcome Associations with Treatment Resistant Hypertension in GenHAT. Int J Hypertens 2013; 2013: 578578.
    • (2013) Int J Hypertens , vol.2013 , pp. 578578
    • Lynch, A.I.1    Irvin, M.R.2    Davis, B.R.3    Ford, C.E.4    Eckfeldt, J.H.5    Arnett, D.K.6
  • 48
    • 79960935778 scopus 로고    scopus 로고
    • Gene variation in resistant hypertension: Multilocus analysis of the angiotensin 1-converting enzyme, angiotensinogen, and endothelial nitric oxide synthase genes
    • Yugar-Toledo JC, Martin JF, Krieger JE, Pereira AC, Demacq C, Coelho OR et al. Gene variation in resistant hypertension: multilocus analysis of the angiotensin 1-converting enzyme, angiotensinogen, and endothelial nitric oxide synthase genes. DNA Cell Biol 2011; 30(8): 555-564.
    • (2011) DNA Cell Biol , vol.30 , Issue.8 , pp. 555-564
    • Yugar-Toledo, J.C.1    Martin, J.F.2    Krieger, J.E.3    Pereira, A.C.4    Demacq, C.5    Coelho, O.R.6
  • 49
    • 75549085532 scopus 로고    scopus 로고
    • ENOS haplotypes affect the responsiveness to antihypertensive therapy in preeclampsia but not in gestational hypertension
    • Sandrim VC, Palei AC, Luizon MR, Izidoro-Toledo TC, Cavalli RC, Tanus-Santos JE. eNOS haplotypes affect the responsiveness to antihypertensive therapy in preeclampsia but not in gestational hypertension. Pharmacogenomics J 2010; 10(1): 40-45.
    • (2010) Pharmacogenomics J , vol.10 , Issue.1 , pp. 40-45
    • Sandrim, V.C.1    Palei, A.C.2    Luizon, M.R.3    Izidoro-Toledo, T.C.4    Cavalli, R.C.5    Tanus-Santos, J.E.6
  • 50
    • 84870063498 scopus 로고    scopus 로고
    • Matrix metalloproteinase-9 polymorphisms affect plasma MMP-9 levels and antihypertensive therapy responsiveness in hypertensive disorders of pregnancy
    • Palei AC, Sandrim VC, Amaral LM, Machado JS, Cavalli RC, Lacchini R et al. Matrix metalloproteinase-9 polymorphisms affect plasma MMP-9 levels and antihypertensive therapy responsiveness in hypertensive disorders of pregnancy. Pharmacogenomics J 2012; 12(6): 489-498.
    • (2012) Pharmacogenomics J , vol.12 , Issue.6 , pp. 489-498
    • Palei, A.C.1    Sandrim, V.C.2    Amaral, L.M.3    Machado, J.S.4    Cavalli, R.C.5    Lacchini, R.6
  • 51
    • 84927175067 scopus 로고    scopus 로고
    • Tissue inhibitor of matrix metalloproteinase-1 polymorphism, plasma TIMP-1 levels, and antihypertensive therapy responsiveness in hypertensive disorders of pregnancy
    • e-pub ahead of print 10 June 2014
    • Luizon MR, Palei ACT, Sandrim VC, Amaral LM, Machado JSR, Lacchini R et al. Tissue inhibitor of matrix metalloproteinase-1 polymorphism, plasma TIMP-1 levels, and antihypertensive therapy responsiveness in hypertensive disorders of pregnancy. Pharmacogenomics J (e-pub ahead of print 10 June 2014; doi:10.1038/tpj.2014.26).
    • Pharmacogenomics J
    • Luizon, M.R.1    Act, P.2    Sandrim, V.C.3    Amaral, L.M.4    Jsr, M.5    Lacchini, R.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.