Association of chromosome 12 locus with antihypertensive response to hydrochlorothiazide may involve differential YEATS4 expression

Pharmacogenomics Journal

Volumn 13, Issue 3, 2013, Pages 257-263

  Duarte, J D ^a,b   Turner, S T ^c   Tran, B ^a   Chapman, A B ^d   Bailey, K R ^c   Gong, Y ^a   Gums, J G ^a,e   Langaee, T Y ^a   Beitelshees, A L ^f   Cooper Dehoff, R M ^a,e   Boerwinkle, E ^g   Johnson, J A ^a,e  

^a UNIVERSITY OF FLORIDA   (United States)

^b UNIVERSITY OF ILLINOIS AT CHICAGO   (United States)

^c MAYO CLINIC   (United States)

^d EMORY UNIVERSITY SCHOOL OF MEDICINE   (United States)

^e UNIVERSITY OF FLORIDA COLLEGE OF MEDICINE   (United States)

^f UNIVERSITY OF MARYLAND SCHOOL OF MEDICINE   (United States)

^g UNIVERSITY OF TEXAS MEDICAL SCHOOL   (United States)

Author keywords

Blood pressure; diuretics; hydrochlorothiazide; hypertension; YEATS4

Indexed keywords

ATENOLOL; CYSTEINE; HYDROCHLOROTHIAZIDE;

ADOLESCENT; ADULT; AFRICAN AMERICAN; AGED; ARTICLE; CAUCASIAN; CHROMOSOMAL LOCALIZATION; CHROMOSOME 12; CHROMOSOME 12Q; DIASTOLIC BLOOD PRESSURE; DOSE RESPONSE; DRUG DOSE ESCALATION; ESSENTIAL HYPERTENSION; FEMALE; GENE; GENE EXPRESSION; GENE FREQUENCY; GENE FUNCTION; GENE LOCUS; GENETIC ANALYSIS; GENETIC ASSOCIATION; GENETIC VARIABILITY; HAPLOTYPE; HETEROZYGOTE; HUMAN; HUMAN CELL; LEUKOCYTE COUNT; MAJOR CLINICAL STUDY; MALE; MULTICENTER STUDY (TOPIC); PHARMACOGENOMICS; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL (TOPIC); SINGLE NUCLEOTIDE POLYMORPHISM; SYSTOLIC BLOOD PRESSURE; YEATS DOMAIN CONTAINING 4 GENE;

ADULT; AFRICAN AMERICANS; ANTIHYPERTENSIVE AGENTS; ATENOLOL; BLOOD PRESSURE; CHROMOSOMES, HUMAN, PAIR 12; CLINICAL TRIALS AS TOPIC; EUROPEAN CONTINENTAL ANCESTRY GROUP; FEMALE; GENE EXPRESSION REGULATION; GENOME-WIDE ASSOCIATION STUDY; GENOTYPE; HAPLOTYPES; HUMANS; HYDROCHLOROTHIAZIDE; HYPERTENSION; MALE; MIDDLE AGED; POLYMORPHISM, SINGLE NUCLEOTIDE; TRANSCRIPTION FACTORS;

EID: 84878251897     PISSN: 1470269X     EISSN: 14731150     Source Type: Journal    
DOI: 10.1038/tpj.2012.4     Document Type: Article

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