Gait mechanics in patients with chronic obstructive pulmonary disease

Respiratory Research

Volumn 16, Issue 1, 2015, Pages

  Yentes, Jennifer M ^a   Schmid, Kendra K ^b   Blanke, Daniel ^a   Romberger, Debra J ^c,d   Rennard, Stephen I ^d   Stergiou, Nicholas ^a,b  

^a UNIVERSITY OF NEBRASKA AT OMAHA   (United States)

^b UNIVERSITY OF NEBRASKA MEDICAL CENTER   (United States)

^c DEPARTMENT OF VETERANS AFFAIRS   (United States)

^d UNIVERSITY OF NEBRASKA MEDICAL CENTER   (United States)

Author keywords

Biomechanics; Joint kinematics; Joint kinetics; Locomotion; Pulmonary disease

Indexed keywords

ADULT; ANKLE; ARTICLE; BIOMECHANICS; CHRONIC OBSTRUCTIVE LUNG DISEASE; CLINICAL ARTICLE; CONTROLLED STUDY; DISEASE SEVERITY; DYSPNEA; EFFECT SIZE; FALL RISK; FATIGUE; FEMALE; GAIT; HIP; HUMAN; KNEE FUNCTION; MALE; MIDDLE AGED; STANDING; TREADMILL EXERCISE; WALKING; WALKING SPEED; AGED; CASE CONTROL STUDY; COMPLICATION; EXERCISE TEST; EXERCISE TOLERANCE; GAIT DISORDERS, NEUROLOGIC; MUSCLE FATIGUE; PATHOPHYSIOLOGY; PROCEDURES; PULMONARY DISEASE, CHRONIC OBSTRUCTIVE; TIME FACTOR;

AGED; ANKLE; BIOMECHANICAL PHENOMENA; CASE-CONTROL STUDIES; EXERCISE TEST; EXERCISE TOLERANCE; FEMALE; GAIT; GAIT DISORDERS, NEUROLOGIC; HUMANS; MALE; MIDDLE AGED; MUSCLE FATIGUE; PULMONARY DISEASE, CHRONIC OBSTRUCTIVE; TIME FACTORS; WALKING;

EID: 84927757511     PISSN: 14659921     EISSN: 1465993X     Source Type: Journal    
DOI: 10.1186/s12931-015-0187-5     Document Type: Article

References (82)

1. Murray CJ, Lopez AD. Global mortality, disability, and the contribution of risk factors: Global Burden of Disease Study. Lancet 1997, 349(9063):1436-42. 10.1016/S0140-6736(96)07495-8, 9164317.
2. Fabbri LM, Rabe KF. From COPD to chronic systemic inflammatory syndrome?. Lancet 2007, 370(9589):797-9. 10.1016/S0140-6736(07)61383-X, 17765529.
3. Nici L, Donner C, Wouters E, Zuwallack R, Ambrosino N, Bourbeau J, et al. Skeletal muscle dysfunction in chronic obstructive pulmonary disease A statement of the American Thoracic Society and European Respiratory Society. Am J Respir Crit Care Med 1999, 159(4):S1-40.
4. Allaire J, Maltais F, Doyon J, Noël M, LeBlanc P, Carrier G, et al. Peripheral muscle endurance and the oxidative profile of the quadriceps in patients with COPD. Thorax 2004, 59(8):673-8. 10.1136/thx.2003.020636, 15282387.
5. Bernard S, LeBlanc P, Whittom F, Carrier G, Jobin J, Belleau R, et al. Peripheral muscle weakness in patients with chronic obstructive pulmonary disease. Am J Respir Crit Care Med 1998, 158(2):629-34. 10.1164/ajrccm.158.2.9711023, 9700144.
6. Gosker HR, van Mameren H, van Dijk PJ, Engelen MPKJ, van der Vusse GJ, Wouters EFM, et al. Skeletal muscle fibre-type shifting and metabolic profile in patients with chronic obstructive pulmonary disease. Eur Respir J 2002, 19(4):617-25. 10.1183/09031936.02.00762001, 11998989.
7. Hamilton AL, Killian KJ, Summers E, Jones NL. Muscle strength, symptom intensity, and exercise capacity in patients with cardiorespiratory disorders. Am J Respir Crit Care Med 1995, 152(6):2021-31. 10.1164/ajrccm.152.6.8520771, 8520771.
8. Hamilton AL, Killian KJ, Summers E, Jones NL. Symptom intensity and subjective limitation to exercise in patients with cardiorespiratory disorders. Chest 1996, 110(5):1255-63. 10.1378/chest.110.5.1255, 8915230.
9. Mador MJ, Deniz O, Aggarwal A, Kufel TJ. Quadriceps fatigability after single muscle exercise in patients with chronic obstructive pulmonary disease. Am J Respir Crit Care Med 2003, 168(1):102-8. 10.1164/rccm.200202-080OC, 12689846.
10. Maltais F, LeBlanc P, Whittom F, Simard C, Marquis K, Bélanger M, et al. Oxidative enzyme activities of the vastus lateralis muscle and the functional status in patients with COPD. Thorax 2000, 55(10):848-53. 10.1136/thorax.55.10.848, 10992537.
11. Wouters EFM, Creutzberg EC, Schols AMWJ. Systemic effects in COPD. Chest 2002, 121(5):127S-130s. 10.1378/chest.121.5_suppl.127S, 12010840.
12. Peruzza S, Sergi G, Vianello A, Pisent C, Tiozzo F, Manzan A, et al. Chronic obstructive pulmonary disease (COPD) in elderly subjects: impact on functional status and quality of life. Respir Med 2003, 97(6):612-7. 10.1053/rmed.2003.1488, 12814144.
13. Pitta F, Troosters T, Probst VS, Spruit MA, Decramer M, Gosselink R. Physical activity and hospitalization for exacerbation of COPD. Chest 2006, 129(3):536-44. 10.1378/chest.129.3.536, 16537849.
14. Garcia-Aymerich J, Félez MA, Escarrabill J, Marrades RM, Morera J, Elosua R, et al. Physical activity and its determinants in severe chronic obstructive pulmonary disease. Med Sci Sports Exerc 2004, 36(10):1667-73. 10.1249/01.MSS.0000142378.98039.58, 15595285.
15. Pitta F, Troosters T, Spruit MA, Probst VS, Decramer M, Gosselink R. Characteristics of physical activities in daily life in chronic obstructive pulmonary disease. Am J Respir Crit Care Med 2005, 171(9):972-7. 10.1164/rccm.200407-855OC, 15665324.
16. Saey D, Debigare R, LeBlanc P, Mador MJ, Cote CH, Jobin J, et al. Contractile leg fatigue after cycle exercise: a factor limiting exercise in patients with chronic obstructive pulmonary disease. Am J Respir Crit Care Med 2003, 168(4):425-30. 10.1164/rccm.200208-856OC, 12714348.
17. Gagnon P, Saey D, Vivodtzev I, Laviolette L, Mainguy V, Milot J, et al. Impact of preinduced quadriceps fatigue on exercise response in chronic obstructive pulmonary disease and healthy subjects. J Appl Physiol 2009, 107(3):832-40. 10.1152/japplphysiol.91546.2008, 19574500.
18. Alexandre F, Heraud N, Oliver N, Varray A. Cortical implications in lower voluntary muscle force production in non-hypoxemic COPD patients. PLoS One 2014, 9(6):e100961. 10.1371/journal.pone.0100961, 24971775.
19. Debigare R, Maltais F. The major limitation to exercise performance in COPD is lower limb muscle dysfunction. J Appl Physiol 2008, 105(2):751-3. 10.1152/japplphysiol.90336.2008a, 18678623.
20. Yentes JM, Sayles H, Meza J, Mannino DM, Rennard SI, Stergiou N. Walking abnormalities are associated with COPD: an investigation of the NHANES III dataset. Respir Med 2011, 105(1):80-7. 10.1016/j.rmed.2010.06.007, 20615681.
21. Annegarn J, Spruit MA, Savelberg HHCM, Willems PJB, Van DB, Schols AMWJ, et al. Differences in walking pattern during 6-min walk test between patients with COPD and healthy subjects. PLoS One 2012, 7(5):e37329. 10.1371/journal.pone.0037329, 22624017.
22. Winter D. Biomechanics and Motor Control of Human Movement 2005, Hoboken, New Jersey, John Wiley & Sons, Inc.
23. Baker R, Robb J. Foot models for clinical gait analysis. Gait Posture 2006, 23(4):399-400. 10.1016/j.gaitpost.2006.03.005, 16621568.
24. Fosang A, Baker R. A method for comparing manual muscle strength measurements with joint moments during walking. Gait Posture 2006, 24(4):406-11. 10.1016/j.gaitpost.2005.09.015, 16412640.
25. Chang FF, Seidl AJ, Muthusamy K, Meininger AK, Carollo JJ. Effectiveness of instrumented gait analysis in children with cerebral palsy-comparison of outcomes. J Pediatr Orthop 2006, 26(5):612-6. 10.1097/01.bpo.0000229970.55694.5c, 16932100.
26. Kawamura CM, de Morais Filho MC, Barreto MM, de Paula Asa SK, Juliano Y, Novo NF. Comparison between visual and three-dimensional gait analysis in patients with spastic diplegic cerebral palsy. Gait Posture 2007, 25(1):18-24. 10.1016/j.gaitpost.2005.12.005, 16431106.
27. Romkes J, Hell AK, Brunner R. Changes in muscle activity in children with hemiplegic cerebral palsy while walking with and without ankle-foot orthoses. Gait Posture 2006, 24(4):467-74. 10.1016/j.gaitpost.2005.12.001, 16413188.
28. McGinley JL, Morris ME, Greenwood KM, Goldie PA, Olney SJ. Accuracy of clinical observations of push-off during gait after stroke. Arch Phys Med Rehabil 2006, 87(6):779-85. 10.1016/j.apmr.2006.02.022, 16731212.
29. Tenore N, Fortugno F, Viola F, Galli M, Giaquinto S. Gait analysis as a reliable tool for rehabilitation of chronic hemiplegic patients. Clin Exp Hypertens 2006, 28(3-4):349-55. 10.1080/10641960600549504, 16833045.
30. Yavuzer G, Eser F, Karakus D, Karaoglan B, Stam HJ. The effects of balance training on gait late after stroke: a randomized controlled trial. Clin Rehabil 2006, 20(11):960-9. 10.1177/0269215506070315, 17065539.
31. Basford JR, Chou L, Kaufman KR, Brey RH, Walker A, Malec JF, et al. An assessment of gait and balance deficits after traumatic brain injury. Arch Phys Med Rehabil 2003, 84(3):343-9. 10.1053/apmr.2003.50034, 12638101.
32. Horn TS, Yablon SA, Stokic DS. Effect of intrathecal baclofen bolus injection on temporospatial gait characteristics in patients with acquired brain injury. Arch Phys Med Rehabil 2005, 86(6):1127-33. 10.1016/j.apmr.2004.11.013, 15954050.
33. Vallée M, McFadyen BJ, Swaine B, Doyon J, Cantin J, Dumas D. Effects of environmental demands on locomotion after traumatic brain injury. Arch Phys Med Rehabil 2006, 87(6):806-13. 10.1016/j.apmr.2006.02.031, 16731216.
34. Runge M, Hunter G. Determinants of musculoskeletal frailty and the risk of falls in old age. J Musculoskelet Neuronal Interact 2006, 6(2):167-73. 16849828.
35. Kerr C, McDowell B, Cosgrove A, Walsh D, Bradbury I, McDonough S. Electrical stimulation in cerebral palsy: a randomized controlled trial. Dev Med Child Neurol 2006, 48(11):870-6. 10.1017/S0012162206001915, 17044952.
36. Barker SP, Freedman W, Hillstrom H. A novel method of producing a repetitive dynamic signal to examine reliability and validity of gait analysis systems. Gait Posture 2006, 24(4):448-52. 10.1016/j.gaitpost.2005.09.008, 16413189.
37. Vestbo J, Hurd SS, Agusti AG, Jones PW, Vogelmeier C, Anzueto A, et al. Global strategy for the diagnosis, management, and prevention of chronic obstructive pulmonary disease: GOLD executive summary. Am J Respir Crit Care Med 2013, 187(4):347-65. 10.1164/rccm.201204-0596PP, 22878278.
38. Houck JR, Duncan A, De Haven KE. Knee and hip angle and moment adaptations during cutting tasks in subjects with anterior cruciate ligament deficiency classified as noncopers. J Orthop Sports Phys Ther 2005, 35(8):531-40. 10.2519/jospt.2005.35.8.531, 16187513.
39. Jackson KM. Fitting of mathematical functions to biomechanical data. IEEE Trans Biomed Eng 1979, 26(2):122-4. 10.1109/TBME.1979.326551, 761932.
40. Dempster W. Space Requirements of the Seated Operator: Geometrical, Kinematic, and Mechanical Aspects of the Body With Special Reference to the Limbs 1955, WADC Technical Report, Dayton, OH.
41. Han MK, Agusti A, Calverley PM, Celli BR, Criner G, Curtis JL, et al. Chronic obstructive pulmonary disease phenotypes: the future of COPD. Am J Respir Crit Care Med 2010, 182(5):598-604. 10.1164/rccm.200912-1843CC, 20522794.
42. Chen X, Xu X, Xiao F. Heterogeneity of chronic obstructive pulmonary disease: from phenotype to genotype. Front Med 2013, 7(4):425-32. 10.1007/s11684-013-0295-x, 24234678.
43. Marquis N, Debigaré R, Bouyer L, Saey D, Laviolette L, Brouillard C, et al. Physiology of walking in patients with moderate to severe chronic obstructive pulmonary disease. Med Sci Sports Exerc 2009, 41:1540-8. 10.1249/MSS.0b013e31819c717f, 19568207.
44. Saey D, Côté CH, Mador MJ, Laviolette L, LeBlanc P, Jobin J, et al. Assessment of muscle fatigue during exercise in chronic obstructive pulmonary disease. Muscle Nerve 2006, 34(1):62-71. 10.1002/mus.20541, 16583366.
45. DeVita P, Hortobagyi T. Age causes a redistribution of joint torques and powers during gait. J Appl Physiol 2000, 88(5):1804-11. 10797145.
46. Bruening, DA, Frimenko, RE, Goodyear, CD, Bowden, DR, Fullenkamp, AM. Sex differences in whole body gait kinematics at preferred speeds. Gait and Posture 2014; doi:10.1016/j.gaitpost.2014.12.011..
47. Kerrigan DC, Todd MK, Della Croce U. Gender differences in joint biomechanics during walking: normative study in young adults. Am J Phys Med Rehabil 1998, 77(1):2-7. 10.1097/00002060-199801000-00002, 9482373.
48. Degens, H, Gayan-Ramirez, G, van Hees, HWH. Smoking-induced skeletal muscle dysfunction: From evidence to mechanisms. American Journal of Respiratory Critical Care Medicine 2015; doi: 10.1164/rccm.201410-1830PP..
49. Caron M, Morissette MC, Theriault M, Nikota JK, Shen P, Staempfli MR, et al. Altered skeletal muscle homeostasis in a Pre-clinical model of cigarette smoke exposure. Am J Respir Crit Care Med 2011, 183:A2529.
50. Gosker HR, Hesselink MK, Duimel H, Ward KA, Schols AM. Reduced mitochondrial density in the vastus lateralis muscle of patients with COPD. Eur Respir J 2007, 30(1):73-9. 10.1183/09031936.00146906, 17428811.
51. Allaire J, Maltais F, LeBlanc P, Simard P, Whittom F, Doyon J, et al. Lipofuscin accumulation in the vastus lateralis muscle in patients with chronic obstructive pulmonary disease. Muscle Nerve 2002, 25(3):383-9. 10.1002/mus.10039, 11870715.
52. Whittom F, Jobin J, Simard PM, Leblanc P, Simard C, Bernard S, et al. Histochemical and morphological characteristics of the vastus lateralis muscle in patients with chronic obstructive pulmonary disease. Med Sci Sports Exerc 1998, 30(10):1467-74. 10.1097/00005768-199810000-00001, 9789845.
53. Gagnon P, Maltais F, Bouyer L, Ribeiro F, Coats V, Brouillard C, et al. Distal leg muscle function in patients with COPD. COPD 2013, 10(2):235-42. 10.3109/15412555.2012.719047, 23547635.
54. Maddocks M, Jones M, Snell T, Connolly B, de Wolf-Linder S, Moxham J, et al. Ankle dorsiflexor muscle size, composition and force with ageing and chronic obstructive pulmonary disease. Exp Physiol 2014, 99(8):1078-88. 10.1113/expphysiol.2014.080093, 24928952.
55. Wüst RCI, Degens H. Factors contributing to muscle wasting and dysfunction in COPD patients. Int J Chron Obstruct Pulmon Dis 2007, 2(3):289-300. 18229567.
56. Aliverti A, Macklem PT. Point: counterpoint: the major limitation to exercise performance in COPD is: 1) inadequate energy supply to the respiratory and locomotor muscles, 2) lower limb muscle dysfunction, 3) dynamic hyperinflation. J Appl Physiol 2008, 105(2):749-51. 10.1152/japplphysiol.90336.2008, 18678622.
57. Austin KG, Mengelkoch L, Hansen J, Shahady E, Sirithienthad P, Panton L. Comparison of oxygenation in peripheral muscle during submaximal aerobic exercise, in persons with COPD and healthy, matched-control persons. Int J Chron Obstruct Pulmon Dis 2006, 1(4):467-75. 18044103.
58. Beauchamp MK, Hill K, Goldstein RS, Janaudis-Ferreira T, Brooks D. Impairments in balance discriminate fallers from non-fallers in COPD. Respir Med 2009, 103(12):1885-91. 10.1016/j.rmed.2009.06.008, 19592229.
59. Beauchamp MK, Sibley KM, Lakhani B, Romano J, Mathur S, Goldstein RS, et al. Impairments in systems underlying control of balance in COPD. Chest 2012, 141(6):1496-503. 10.1378/chest.11-1708, 22116798.
60. Janssens L, Brumagne S, McConnell AK, Claeys K, Pijnenburg M, Burtin C, et al. Proprioceptive changes impair balance control in individuals with chronic obstructive pulmonary disease. PLoS One 2013, 8(3):e57949. 10.1371/journal.pone.0057949, 23469255.
61. Ozalevli S, Ilgin D, Narin S, Akkoclu A. Association between disease-related factors and balance and falls among the elderly with COPD: a cross-sectional study. Aging Clin Exp Res 2011, 23(5-6):372-7. 10.1007/BF03325235, 22526071.
62. Nordin E, Moe-Nilssen R, Ramnemark A, Lundin-Olsson L. Changes in step-width during dual-task walking predicts falls. Gait Posture 2010, 32(1):92-7. 10.1016/j.gaitpost.2010.03.012, 20399100.
63. Schulz BW. Healthy younger and older adults control foot placement to avoid small obstacles during gait primarily by modulating step width. J Neuroeng Rehabil 2012, 9:69-0003-9-69. 10.1186/1743-0003-9-69.
64. Schrager MA, Kelly VE, Price R, Ferrucci L, Shumway-Cook A. The effects of age on medio-lateral stability during normal and narrow base walking. Gait Posture 2008, 28(3):466-71. 10.1016/j.gaitpost.2008.02.009, 18400500.
65. Dean JC, Alexander NB, Kuo AD. The effect of lateral stabilization on walking in young and old adults. IEEE Trans Biomed Eng 2007, 54(11):1919-26. 10.1109/TBME.2007.901031, 18018687.
66. Owings TM, Grabiner MD. Step width variability, but not step length variability or step time variability, discriminates gait of healthy young and older adults during treadmill locomotion. J Biomech 2004, 37(6):935-8. 10.1016/j.jbiomech.2003.11.012, 15111081.
67. Brach JS, Studenski S, Perera S, VanSwearingen JM, Newman AB. Stance time and step width variability have unique contributing impairments in older persons. Gait Posture 2008, 27(3):431-9. 10.1016/j.gaitpost.2007.05.016, 17632004.
68. Brach JS, Berlin JE, VanSwearingen JM, Newman AB, Studenski SA. Too much or too little step width variability is associated with a fall history in older persons who walk at or near normal gait speed. J Neuroeng Rehabil 2005, 2:21. 10.1186/1743-0003-2-21, 16042812.
69. Decramer M, Rennard S, Troosters T, Mapel DW, Giardino N, Mannino D, et al. COPD as a lung disease with systemic consequences-clinical impact, mechanisms, and potential for early intervention. COPD 2008, 5(4):235-56. 10.1080/15412550802237531, 18671149.
70. Rennard SI. COPD heterogeneity: what this will mean in practice. Respir Care 2011, 56(8):1181-7. 10.4187/respcare.01419, 21801580.
71. Barnes PJ, Celli BR. Systemic manifestations and comorbidities of COPD. Eur Respir J 2009, 33(5):1165-85. 10.1183/09031936.00128008, 19407051.
72. Spurzem JR, Rennard SI. Pathogenesis of COPD. Semin Respir Crit Care Med 2005, 26(2):142-53. 10.1055/s-2005-869535, 16088433.
73. Sin DD, Man SFP. Skeletal muscle weakness, reduced exercise tolerance, and COPD: is systemic inflammation the missing link?. Thorax 2006, 61(1):1-3. 10.1136/thx.2005.044941, 16396949.
74. Coronell C, Orozco-Levi M, Méndez R, Ramírez-Sarmiento A, Gáldiz JB, Gea J. Relevance of assessing quadriceps endurance in patients with COPD. Eur Respir J 2004, 24(1):129-36. 10.1183/09031936.04.00079603, 15293615.
75. Biskobing DM. COPD and osteoporosis. Chest 2002, 121(2):609-20. 10.1378/chest.121.2.609, 11834678.
76. Ciric Z, Stankovic I, Pejcic T, Ristic L, Rancic M, Radovic M. Osteoporosis in patients with chronic obstructive pulmonary disease. Med Arh 2012, 66(6):385-7. 10.5455/medarh.2012.66.385-387.
77. Romme EA, Rutten EP, Geusens P, de Jong JJ, van Rietbergen B, Smeenk FW, et al. Bone stiffness and failure load are related with clinical parameters in men with chronic obstructive pulmonary disease. J Bone Miner Res 2013, 28(10):2186-93. 10.1002/jbmr.1947, 23553944.
78. Mannino DM, Thorn D, Swensen A, Holguin F. Prevalence and outcomes of diabetes, hypertension and cardiovascular disease in COPD. Eur Respir J 2008, 32(4):962-9. 10.1183/09031936.00012408, 18579551.
79. Caughey GE, Preiss AK, Vitry AI, Gilbert AL, Roughead EE. Comorbid Diabetes and COPD: Impact of corticosteroid use on diabetes complications. Diabetes Care 2013, 36(10):3009-14. 10.2337/dc12-2197, 23735725.
80. Hellstrom K, Vahlberg B, Urell C, Emtner M. Fear of falling, fall-related self-efficacy, anxiety and depression in individuals with chronic obstructive pulmonary disease. Clin Rehabil 2009, 23(12):1136-44. 10.1177/0269215509342329, 19906765.
81. Mikkelsen RL, Middelboe T, Pisinger C, Stage KB. Anxiety and depression in patients with chronic obstructive pulmonary disease (COPD). A review Nord J Psychiatrys 2004, 58(1):65-70. 10.1080/08039480310000824.
82. Quint JK, Baghai-Ravary R, Donaldson GC, Wedzicha JA. Relationship between depression and exacerbations in COPD. Eur Respir J 2008, 32(1):53-60. 10.1183/09031936.00120107, 18321938.