Imbalance of dendritic cell co-stimulation in COPD

Respiratory Research

Volumn 16, Issue 1, 2015, Pages

  Stoll, Paul ^a   Ulrich, Martin ^a   Bratke, Kai ^a   Garbe, Katharina ^a   Virchow, J C ^a   Lommatzsch, Marek ^a  

^a UNIVERSITY OF ROSTOCK   (Germany)

Author keywords

Chronic inflammation; COPD; Dendritic cells; Emphysema

Indexed keywords

25 HYDROXYVITAMIN D; BLOOD DENDRITIC CELL ANTIGEN 1; BLOOD DENDRITIC CELL ANTIGEN 3; C REACTIVE PROTEIN; CD86 ANTIGEN; CELL SURFACE MARKER; CHEMOKINE RECEPTOR CCR5; FIBRINOGEN; INTERCELLULAR ADHESION MOLECULE 1; INTERLEUKIN 6; OX40 LIGAND; PROGRAMMED DEATH 1 LIGAND 1; UNCLASSIFIED DRUG; AUTACOID; BIOLOGICAL MARKER; CYTOKINE; MEMBRANE ANTIGEN;

ADULT; AGED; ARTICLE; CHRONIC OBSTRUCTIVE LUNG DISEASE; CONTROLLED STUDY; FEMALE; FLOW CYTOMETRY; HUMAN; HUMAN CELL; IMMUNOPATHOGENESIS; IMMUNOSTIMULATION; INFLAMMATION; LEUKOCYTE; LUNG EMPHYSEMA; LUNG FUNCTION; MAJOR CLINICAL STUDY; MALE; MIDDLE AGED; MYELOID DENDRITIC CELL; PLASMACYTOID DENDRITIC CELL; PROTEIN EXPRESSION; QUANTITATIVE ANALYSIS; SMOKING; ADVERSE EFFECTS; BLOOD; CASE CONTROL STUDY; DENDRITIC CELL; FORCED EXPIRATORY VOLUME; IMMUNOLOGY; LUNG; METABOLISM; PATHOPHYSIOLOGY; PHYSIOLOGY; PULMONARY DISEASE, CHRONIC OBSTRUCTIVE; PULMONARY EMPHYSEMA; SEVERITY OF ILLNESS INDEX; VERY ELDERLY;

ADULT; AGED; AGED, 80 AND OVER; ANTIGENS, SURFACE; BIOMARKERS; CASE-CONTROL STUDIES; CYTOKINES; DENDRITIC CELLS; FEMALE; FLOW CYTOMETRY; FORCED EXPIRATORY VOLUME; HUMANS; INFLAMMATION MEDIATORS; LUNG; MALE; MIDDLE AGED; PULMONARY DISEASE, CHRONIC OBSTRUCTIVE; PULMONARY EMPHYSEMA; SEVERITY OF ILLNESS INDEX; SMOKING;

EID: 84927731765     PISSN: 14659921     EISSN: 1465993X     Source Type: Journal    
DOI: 10.1186/s12931-015-0174-x     Document Type: Article

References (37)

1. Brusselle GG, Joos GF, Bracke KR. New insights into the immunology of chronic obstructive pulmonary disease. Lancet 2011, 378:1015-26. 10.1016/S0140-6736(11)60988-4, 21907865.
2. Lokke A, Lange P, Scharling H, Fabricius P, Vestbo J. Developing COPD: a 25 year follow up study of the general population. Thorax 2006, 61:935-9. 10.1136/thx.2006.062802, 17071833.
3. Demedts IK, Bracke KR, Van Pottelberge G, Testelmans D, Verleden GM, Vermassen FE, et al. Accumulation of dendritic cells and increased CCL20 levels in the airways of patients with chronic obstructive pulmonary disease. Am J Respir Crit Care Med 2007, 175:998-1005. 10.1164/rccm.200608-1113OC, 17332482.
4. Van Pottelberge GR, Bracke KR, Demedts IK, De Rijck K, Reinartz SM, van Drunen CM, et al. Selective accumulation of langerhans-type dendritic cells in small airways of patients with COPD. Respir Res 2010, 11:35. 10.1186/1465-9921-11-35, 20307269.
5. Van Pottelberge GR, Bracke KR, Van den Broeck S, Reinartz SM, van Drunen CM, Wouters EF, et al. Plasmacytoid dendritic cells in pulmonary lymphoid follicles of patients with COPD. Eur Respir J 2010, 36:781-91. 10.1183/09031936.00140409, 20351031.
6. Vassallo R, Walters PR, Lamont J, Kottom TJ, Yi ES, Limper AH. Cigarette smoke promotes dendritic cell accumulation in COPD; a Lung Tissue Research Consortium study. Respir Res 2010, 11:45. 10.1186/1465-9921-11-45, 20420706.
7. Mori M, Andersson CK, Svedberg KA, Glader P, Bergqvist A, Shikhagaie M, et al. Appearance of remodelled and dendritic cell-rich alveolar-lymphoid interfaces provides a structural basis for increased alveolar antigen uptake in chronic obstructive pulmonary disease. Thorax 2013, 68:521-31. 10.1136/thoraxjnl-2012-202879, 23412435.
8. Tsoumakidou M, Demedts IK, Brusselle GG, Jeffery PK. Dendritic cells in chronic obstructive pulmonary disease: new players in an old game. Am J Respir Crit Care Med 2008, 177:1180-6. 10.1164/rccm.200711-1727PP, 18337593.
9. Brusselle GG, Demoor T, Bracke KR, Brandsma CA, Timens W. Lymphoid follicles in (very) severe COPD: beneficial or harmful?. Eur Respir J 2009, 34:219-30. 10.1183/09031936.00150208, 19567605.
10. Bratke K, Lommatzsch M, Julius P, Kuepper M, Kleine HD, Luttmann W, et al. Dendritic cell subsets in human bronchoalveolar lavage fluid after segmental allergen challenge. Thorax 2007, 62:168-75. 10.1136/thx.2006.067793, 16928719.
11. Bratke K, Klug M, Bier A, Julius P, Kuepper M, Virchow JC, et al. Function-associated surface molecules on airway dendritic cells in cigarette smokers. Am J Respir Cell Mol Biol 2008, 38:655-60. 10.1165/rcmb.2007-0400OC, 18203971.
12. Lommatzsch M, Bratke K, Bier A, Julius P, Kuepper M, Luttmann W, et al. Airway dendritic cell phenotypes in inflammatory diseases of the human lung. Eur Respir J 2007, 30:878-86. 10.1183/09031936.00036307, 17626112.
13. Lommatzsch M, Bratke K, Knappe T, Bier A, Dreschler K, Kuepper M, et al. Acute effects of tobacco smoke on human airway dendritic cells in vivo. Eur Respir J 2010, 35:1130-6. 10.1183/09031936.00090109, 19741025.
14. Stoll P, Heinz AS, Bratke K, Bier A, Garbe K, Kuepper M, et al. Impact of smoking on dendritic cell phenotypes in the airway lumen of patients with COPD. Respir Res 2014, 15:48. 10.1186/1465-9921-15-48, 24742278.
15. Agusti A, Edwards LD, Rennard SI, MacNee W, Tal-Singer R, Miller BE, et al. Persistent systemic inflammation is associated with poor clinical outcomes in COPD: a novel phenotype. PLoS One 2012, 7:e37483. 10.1371/journal.pone.0037483, 22624038.
16. Sharpe AH, Wherry EJ, Ahmed R, Freeman GJ. The function of programmed cell death 1 and its ligands in regulating autoimmunity and infection. Nat Immunol 2007, 8:239-45. 10.1038/ni1443, 17304234.
17. Gollwitzer ES, Saglani S, Trompette A, Yadava K, Sherburn R, McCoy KD, et al. Lung microbiota promotes tolerance to allergens in neonates via PD-L1. Nat Med 2014, 20:642-7. 10.1038/nm.3568, 24813249.
18. Rabe H, Nordstrom I, Andersson K, Lundell AC, Rudin A. Staphylococcus aureus convert neonatal conventional CD4(+) T cells into FOXP3(+) CD25(+) CD127(low) T cells via the PD-1/PD-L1 axis. Immunology 2014, 141:467-81. 10.1111/imm.12209, 24708420.
19. Saresella M, Calabrese E, Marventano I, Piancone F, Gatti A, Farina E, et al. A potential role for the PD1/PD-L1 pathway in the neuroinflammation of Alzheimer's disease. Neurobiol Aging 2012, 33:624. e611-622, 10.1016/j.neurobiolaging.2011.03.004, 21514692.
20. Gehrie E, Van der Touw W, Bromberg JS, Ochando JC. Plasmacytoid dendritic cells in tolerance. Methods Mol Biol 2011, 677:127-47. 10.1007/978-1-60761-869-0_9, 20941607.
21. Kalathil SG, Lugade AA, Pradhan V, Miller A, Parameswaran GI, Sethi S, Thanavala Y. T regulatory cells and PD-1+ T cells contribute to effector T cell dysfunction in COPD patients. Am J Respir Crit Care Med 2014, 190(1):40-50. 10.1164/rccm.201312-2293OC, 24825462.
22. Kaur D, Brightling C. OX40/OX40 ligand interactions in T-cell regulation and asthma. Chest 2012, 141:494-9. 10.1378/chest.11-1730, 22315115.
23. Gauvreau GM, O'Byrne PM, Boulet LP, Wang Y, Cockcroft D, Bigler J, et al. Effects of an anti-TSLP antibody on allergen-induced asthmatic responses. N Engl J Med 2014, 370:2102-10. 10.1056/NEJMoa1402895, 24846652.
24. Ying S, O'Connor B, Ratoff J, Meng Q, Fang C, Cousins D, et al. Expression and cellular provenance of thymic stromal lymphopoietin and chemokines in patients with severe asthma and chronic obstructive pulmonary disease. J Immunol 2008, 181:2790-8. 10.4049/jimmunol.181.4.2790, 18684970.
25. Hodge G, Mukaro V, Reynolds PN, Hodge S. Role of increased CD8/CD28(null) T cells and alternative co-stimulatory molecules in chronic obstructive pulmonary disease. Clin Exp Immunol 2011, 166:94-102. 10.1111/j.1365-2249.2011.04455.x, 21910726.
26. Caramori G, Adcock IM, Di Stefano A, Chung KF. Cytokine inhibition in the treatment of COPD. Int J Chron Obstruct Pulmon Dis 2014, 9:397-412. 24812504.
27. Singh M, Lee SH, Porter P, Xu C, Ohno A, Atmar RL, et al. Human rhinovirus proteinase 2A induces TH1 and TH2 immunity in patients with chronic obstructive pulmonary disease. J Allergy Clin Immunol 2010, 125:1369-78. e1362, 10.1016/j.jaci.2010.02.035, 20430426.
28. Tuder RM, Petrache I. Pathogenesis of chronic obstructive pulmonary disease. J Clin Invest 2012, 122:2749-55. 10.1172/JCI60324, 22850885.
29. Hou J, Sun Y, Hao Y, Zhuo J, Liu X, Bai P, et al. Imbalance between subpopulations of regulatory T cells in COPD. Thorax 2013, 68:1131-9. 10.1136/thoraxjnl-2012-201956, 23749814.
30. Bracke KR, Demedts IK, Joos GF, Brusselle GG. CC-chemokine receptors in chronic obstructive pulmonary disease. Inflamm Allergy Drug Targets 2007, 6:75-9. 10.2174/187152807780832292, 17692030.
31. Bracke KR, D'Hulst AI, Maes T, Demedts IK, Moerloose KB, Kuziel WA, et al. Cigarette smoke-induced pulmonary inflammation, but not airway remodelling, is attenuated in chemokine receptor 5-deficient mice. Clin Exp Allergy 2007, 37:1467-79. 17883726.
32. Di Stefano A, Caramori G, Gnemmi I, Contoli M, Bristot L, Capelli A, et al. Association of increased CCL5 and CXCL7 chemokine expression with neutrophil activation in severe stable COPD. Thorax 2009, 64:968-75. 10.1136/thx.2009.113647, 19703829.
33. Capelli A, Di Stefano A, Gnemmi I, Balbo P, Cerutti CG, Balbi B, et al. Increased MCP-1 and MIP-1beta in bronchoalveolar lavage fluid of chronic bronchitics. Eur Respir J 1999, 14:160-5. 10.1034/j.1399-3003.1999.14a27.x, 10489845.
34. Galgani M, Fabozzi I, Perna F, Bruzzese D, Bellofiore B, Calabrese C, et al. Imbalance of circulating dendritic cell subsets in chronic obstructive pulmonary disease. Clin Immunol 2010, 137:102-10. 10.1016/j.clim.2010.06.010, 20634141.
35. Demedts IK, Brusselle GG, Vermaelen KY, Pauwels RA. Identification and characterization of human pulmonary dendritic cells. Am J Respir Cell Mol Biol 2005, 32:177-84. 10.1165/rcmb.2004-0279OC, 15576669.
36. Freeman CM, Martinez FJ, Han MK, Ames TM, Chensue SW, Todt JC, et al. Lung dendritic cell expression of maturation molecules increases with worsening chronic obstructive pulmonary disease. Am J Respir Crit Care Med 2009, 180:1179-88. 10.1164/rccm.200904-0552OC, 19729666.
37. Dzionek A, Fuchs A, Schmidt P, Cremer S, Zysk M, Miltenyi S, et al. BDCA-2, BDCA-3, and BDCA-4: three markers for distinct subsets of dendritic cells in human peripheral blood. J Immunol 2000, 165:6037-46. 10.4049/jimmunol.165.11.6037, 11086035.